Summary of Study ST000161

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000140. The data can be accessed directly via it's Project DOI: 10.21228/M8W01B This work is supported by NIH grant, U2C- DK119886.

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Study IDST000161
Study TitlePlasma Nucleotide/adenosine concentrations (Human AxP Batch 3)
Study TypeExercise and rest
Study SummaryThis experiment was performed using the following cohorts: 1) healthy controls, 2) patients with scleroderma at low risk for pulmonary hypertension, 3) pateints with scleroderma at high risk for pulmonary hypertension. Whole blood was drawn directly into stop soilution (1:1 ratio) at rest and again at peak exercise for each human subject.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Email mkachman@umich.edu
Submit Date2014-10-27
Num Groups4
Total Subjects24
Raw Data AvailableYes
Raw Data File Type(s)d
Uploaded File Size225 M
Analysis Type DetailLC-MS
Release Date2015-04-28
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M8W01B
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

Select appropriate tab below to view additional metadata details:


Project:

Project ID:PR000140
Project DOI:doi: 10.21228/M8W01B
Project Title:Human AxP Studies
Project Type:Glycolysis/TCA/Nucleotide analysis (tissue/cells)
Project Summary:Plasma Nucleotide/adenosine concentrations
Institute:University of Michigan
Department:Internal Medicine-Cardiology
Laboratory:Visovatti Lab
Last Name:Visovatti
First Name:Scott
Address:Ann Arbor, MI
Email:shv@med.umich.edu
Phone:734-657-6917

Subject:

Subject ID:SU000180
Subject Type:Human
Subject Species:Homo sapiens
Taxonomy ID:9606
Species Group:Human

Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Exercise Group
SA008587S00016694no Healthy
SA008588S00016708no Healthy
SA008589S00016692no Healthy
SA008590S00016696no Healthy
SA008591S00016688no SSc-high
SA008592S00016700no SSc-high
SA008593S00016702no SSc-high
SA008594S00016704no SSc-high
SA008595S00016710no SSc-high
SA008596S00016698no SSc-high
SA008597S00016690no SSc-high
SA008598S00016706no SSc-high
SA008599S00016693yes Healthy
SA008600S00016709yes Healthy
SA008601S00016695yes Healthy
SA008602S00016697yes Healthy
SA008603S00016707yes SSc-high
SA008604S00016711yes SSc-high
SA008605S00016699yes SSc-high
SA008606S00016689yes SSc-high
SA008607S00016691yes SSc-high
SA008608S00016701yes SSc-high
SA008609S00016703yes SSc-high
SA008610S00016705yes SSc-high
Showing results 1 to 24 of 24

Collection:

Collection ID:CO000166
Collection Summary:-
Sample Type:Plasma

Treatment:

Treatment ID:TR000186

Sample Preparation:

Sampleprep ID:SP000180
Sampleprep Summary:-
Sampleprep Protocol Filename:Gly-TCA-nucleotides_analysis_protocol-2015-03-09.docx

Combined analysis:

Analysis ID AN000253
Analysis type MS
Chromatography type HILIC
Chromatography system Agilent 1260
Column Phenomenex Luna NH2 (150 x 1mm,3um)
MS Type ESI
MS instrument type QTOF
MS instrument name Agilent 6520 QTOF
Ion Mode NEGATIVE
Units nM

Chromatography:

Chromatography ID:CH000178
Methods ID:AQM015
Methods Filename:QQQ-ATP,ADP,AMP,A-Insert.m.zip
Instrument Name:Agilent 1260
Column Name:Phenomenex Luna NH2 (150 x 1mm,3um)
Chromatography Type:HILIC

MS:

MS ID:MS000203
Analysis ID:AN000253
Instrument Name:Agilent 6520 QTOF
Instrument Type:QTOF
MS Type:ESI
Ion Mode:NEGATIVE
Acquisition Parameters File:QQQ-ATP,ADP,AMP,A-Insert.m.zip
Processing Parameters File:EX00370-Nucleotides-Quant.m.zip
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