Data for Pharmacometabolomic analysis of rat hippocampus and plasma in response to chronic stress and albiflorin treament (Study ST000903)

HILIC POSITIVE ION MODE (Analysis AN001470): Average values per metabolite and experimental factor (Units:AUC)

Metabolite structureAll dataF1F2F3F4
1-Methyladenine ME230472 89175.00 87525.00 105911.11 109525.00
1-Methyladenosine ME230412 4992500.00 5368750.00 6054444.44 6292500.00
1-Methylhistidine ME230434 5096250.00 6745000.00 5112222.22 7697500.00
2-Arachidonylglycerol ME230374 279625.00 154050.00 147555.56 125375.00
3-Hydroxydodecanoylcarnitine ME230426 705625.00 883375.00 682222.22 728000.00
3-Hydroxyisovaleryl Carnitine ME230413 23087500.00 20350000.00 21833333.33 21537500.00
5,6-trans-25-Hydroxyvitamin D3 ME230361 5120000.00 6626250.00 8266666.67 5386250.00
5-Hydroxyindoleacetic acid ME230466 3378750.00 4128750.00 3996666.67 7902500.00
5-Methyltetrahydrofolic acid ME230468 18178.75 46876.25 48253.33 50437.50
7-ketocholesterol ME230363 3316250.00 3202500.00 3308888.89 1278000.00
8-Hydroxy-deoxyguanosine ME230463 63450.00 117600.00 82022.22 87487.50
Acetylcholine ME230427 48075000.00 51325000.00 53600000.00 67287500.00
Adenine ME230421 1571750.00 1512125.00 1545555.56 1422500.00
Adenosine ME230414 18810000.00 18097500.00 20561111.11 15058750.00
Adenosine monophosphate ME230467 1737500.00 1298500.00 2361666.67 2287625.00
Alanine ME230440 27387500.00 35087500.00 28111111.11 38762500.00
Alpha-Tocopherol ME230358 1302500.00 1392375.00 1443333.33 1167500.00
Biotin ME230431 1288750.00 1038250.00 1028777.78 1093375.00
Butyrylcarnitine ME230403 21212500.00 37237500.00 20111111.11 21000000.00
Carnosine ME230456 946000.00 1115875.00 638777.78 889250.00
Cer(d18:1/18:0) ME230365 798125.00 701625.00 594111.11 669500.00
Cer(d18:1/22:0) ME230366 875750.00 927000.00 852555.56 945625.00
Cer(d18:1/22:0 OH) ME230364 843625.00 836375.00 803111.11 758875.00
Cer(d18:1/23:0) ME230372 926625.00 965000.00 987777.78 1025500.00
Cer(d18:1/24:0) ME230367 2386250.00 2546000.00 2462222.22 2520000.00
Cer(d18:1/24:1) ME230368 8387500.00 8106250.00 8893333.33 8242500.00
Cer(d18:1/24:2) ME230369 3323750.00 3422125.00 3551111.11 3747500.00
Cer(d18:1/25:0) ME230370 3123750.00 3206750.00 3117777.78 3397500.00
Cholesterol ME230360 9960000.00 7097500.00 8125555.56 6927500.00
Choline ME230381 1581250.00 1805000.00 1589333.33 1616250.00
CoQ9 ME230355 60225.00 55600.00 72677.78 40887.50
CoQ9H2 ME230356 13578.75 12992.50 15288.89 11432.50
Corticosterone ME230380 704375.00 638500.00 664000.00 928375.00
Cortisol ME230470 60037.50 73212.50 63555.56 57225.00
Creatine ME230354 304500000.00 315875000.00 297777777.78 348250000.00
Cysteamine ME230397 3307500.00 3378750.00 3233333.33 3237500.00
Cysteine ME230448 77987.50 85012.50 95777.78 92825.00
Cysteine-S-sulfate ME230469 99500.00 72657.50 38388.89 74225.00
Cytidine ME230420 19300000.00 20328750.00 29122222.22 32387500.00
Cytosine ME230411 130250000.00 136837500.00 149222222.22 157375000.00
Dihexosylcer(18:1/16:0) ME230401 102550.00 162525.00 151166.67 141850.00
Dihexosylcer(18:1/24:1) ME230402 14472.50 26475.00 17000.00 18725.00
Dimethylglycine ME230424 93825000.00 99462500.00 110088888.89 102762500.00
Dodecanoylcarnitine ME230394 3763750.00 2820000.00 2900000.00 2678750.00
Dodecenoylcarnitine ME230388 1475000.00 1231000.00 1246888.89 1376250.00
Dopamine ME230460 260250.00 332500.00 297777.78 270375.00
Epinephrine ME230465 312125.00 320750.00 307222.22 302625.00
Ethanolamine ME230418 3711250.00 3778750.00 3573333.33 3872500.00
Gamma-Aminobutyric acid ME230444 25025.00 42725.00 31611.11 38600.00
Glucosylceramide(18:1/16:0) ME230389 98575.00 149512.50 148777.78 137562.50
Glycerophosphocholine ME230433 45137500.00 36837500.00 38388888.89 32362500.00
Glycine ME230455 329375.00 361125.00 361666.67 369750.00
Histamine ME230408 80725000.00 82762500.00 91411111.11 96800000.00
Histidine ME230457 6687500.00 7732500.00 8442222.22 8578750.00
Homoarginine ME230474 887750.00 1043500.00 2805444.44 1254125.00
Hydroxykynurenine ME230417 886000.00 1059375.00 1158888.89 1093125.00
Hypotaurine ME230471 29200.00 81875.00 44577.78 45925.00
Indole ME230438 1628750.00 1476000.00 1902222.22 1822500.00
Isovalerylcarnitine ME230400 70700000.00 57100000.00 69588888.89 58875000.00
L-Acetylcarnitine ME230410 162500000.00 169500000.00 167666666.67 172250000.00
L-Asparagine ME230445 938875.00 1075375.00 1091555.56 1049125.00
L-Carnitine ME230428 23762500.00 23487500.00 23600000.00 22650000.00
L-Glutamic acid ME230462 4658750.00 5137500.00 6543333.33 6973750.00
L-Glutamine ME230446 145375000.00 155750000.00 158111111.11 150375000.00
L-Glutarylcarnitine ME230442 1398750.00 2272500.00 1620000.00 1812500.00
L-Histidinol ME230409 180250.00 181625.00 268222.22 183875.00
Linoleylcarnitine ME230396 6936250.00 7602500.00 5903333.33 10690000.00
L-Kynurenine ME230454 330000.00 310125.00 405333.33 588375.00
L-leucine ME230423 166125000.00 164575000.00 185888888.89 173875000.00
L-Methionine ME230429 20000000.00 21325000.00 22144444.44 24500000.00
L-Palmitoylcarnitine ME230390 457375.00 378500.00 365666.67 432875.00
L-Phenylalanine ME230422 36125000.00 36575000.00 39255555.56 38262500.00
L-Serine ME230450 5085000.00 5071250.00 4968888.89 4993750.00
L-Tryptophan ME230435 51112500.00 53712500.00 64433333.33 62112500.00
L-Tyrosine ME230451 1045250.00 1228000.00 1431000.00 1530000.00
L-Valine ME230430 1102500.00 1277750.00 1470000.00 1224125.00
Lysine ME230458 117250000.00 126412500.00 136555555.56 125000000.00
LysoPC(16:0) ME230393 35050000.00 37025000.00 37011111.11 33575000.00
Malonylcarnitine ME230419 13722500.00 13797500.00 12425555.56 16325000.00
Melatonin ME230382 169125.00 157375.00 149288.89 158875.00
Metanephrine ME230432 954250.00 1221875.00 1043888.89 1168125.00
Methionine sulfoxide ME230439 381500.00 518750.00 409444.44 404625.00
Myristoylcarnitine ME230395 8082500.00 6261250.00 6517777.78 7307500.00
N-alpha-Acetylarginine ME230473 925500.00 1177750.00 869444.44 1913875.00
Niacinamide ME230383 70937500.00 76500000.00 56222222.22 83400000.00
Nicotinamide N-oxide ME230399 21587500.00 25325000.00 22755555.56 25050000.00
N-oleoylethanolamine ME230373 649125.00 412125.00 468222.22 466000.00
Norepinephrine ME230437 148125.00 195125.00 183777.78 166500.00
Normetanephrine ME230416 1777500.00 2257500.00 2032222.22 2085000.00
Octadecanoylcarnitine ME230392 5463750.00 4997500.00 5002222.22 6846250.00
Oleoylcarnitine ME230391 14813750.00 12370000.00 10967777.78 17581250.00
Ornithine ME230453 138925.00 160225.00 145988.89 140175.00
Oxidized glutathione ME230464 7037.50 11735.00 11710.00 6918.75
PC(16:0/16:0) ME230377 9451250.00 12775000.00 11430000.00 12185000.00
PC(16:0/18:1) ME230378 10693750.00 13720000.00 11431111.11 8060000.00
PC(16:0/18:2) ME230385 8316250.00 10987500.00 10423333.33 7870000.00
PC(16:0/20:4) ME230386 4448750.00 5768750.00 5020000.00 4513750.00
PC(16:0/22:6) ME230384 1877500.00 2302500.00 1993333.33 1807500.00
PC(18:0/18:2) ME230379 11625000.00 16325000.00 16744444.44 12662500.00
PC(20:4/P-16:0) ME230387 665875.00 947875.00 724111.11 802875.00
PC(22:6/P-18:0) ME230376 75475.00 103375.00 77100.00 74375.00
Phosphorylcholine ME230452 1615000.00 2777500.00 2796666.67 3296250.00
Pipecolic acid ME230447 122000000.00 129487500.00 138555555.56 135375000.00
Propionylcarnitine ME230406 58637500.00 65962500.00 67611111.11 55512500.00
Purine ME230425 606750.00 613750.00 699555.56 641125.00
Retinal ME230362 76325.00 70862.50 52588.89 79112.50
Retinol ME230357 37637.50 40562.50 43455.56 57312.50
Riboflavin ME230415 38000.00 100062.50 108833.33 104675.00
Saccharopine ME230459 500000.00 756500.00 600000.00 578125.00
S-Adenosylmethionine ME230449 5942.50 7147.50 7294.44 6456.25
Sarcosine ME230441 33612500.00 42062500.00 34722222.22 46537500.00
Serotonin ME230443 873750.00 316250.00 1303333.33 1448125.00
Spermidine ME230461 137850.00 127037.50 142222.22 123925.00
Suberylcarnitine ME230436 2101250.00 2695000.00 2590000.00 2707500.00
Testosterone ME230375 183137.50 162337.50 161111.11 193625.00
Thiamine ME230405 271250.00 303350.00 521111.11 441500.00
Trihexosylcer(18:1/16:0) ME230407 30762.50 41687.50 37533.33 44262.50
Trimethylamine-N-oxide ME230404 137250000.00 139112500.00 154111111.11 98537500.00
Urea ME230398 41962500.00 44087500.00 41322222.22 44512500.00
Vitamin D3 ME230371 1158875.00 1608750.00 1213444.44 1153500.00
Vitamin K2 ME230359 1982500.00 2831000.00 1942777.78 1926250.00

Factors:

F1Genotype:CUMS model | Treatment:Albiflorin
F2Genotype:CUMS model | Treatment:Fluoxetine
F3Genotype:CUMS model | Treatment:Saline
F4Genotype:Wild-type | Treatment:Saline
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