Data for A study of changes in lipid metabolism of ovarian cancer cells co-cultured with adipocytes: UPLC-QTRAP MS analysis (Study ST000096)
(Analysis AN000152)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 11,12,15-THET | 1.0483 | NA | 1.9929 | NA | 0.0974 | NA |
| 11,12-DiHETrE | 1.5643 | NA | 1.4546 | NA | 0.1179 | NA |
| 11(12)-EpETE | NA | NA | NA | NA | NA | NA |
| 11(12)-EpETrE | 1.7267 | 2.3173 | 0.3654 | 1.0537 | 0.0730 | 0.7981 |
| 11-HETE | 2.1609 | 1.1406 | 0.4979 | 1.1160 | 0.0695 | 1.1254 |
| 12,13-DiHODE | NA | NA | NA | NA | NA | NA |
| 12,13-DiHOME | 3.3828 | 0.8311 | 0.9575 | 0.4903 | 0.2215 | 0.3699 |
| 12(13)-Ep-9-KODE | 2.8232 | 0.7236 | 1.6526 | 0.7677 | 0.1097 | 0.1874 |
| 12(13)-EpODE | 2.6585 | NA | 0.4010 | NA | 0.0810 | NA |
| 12(13)-EpOME | 3.2073 | 1.6715 | 0.5251 | 0.5053 | 0.1193 | 0.2187 |
| 12-HEPE | 1.5056 | NA | 0.8784 | NA | 0.6557 | NA |
| 12-HETE | 1.2537 | 2.5486 | 0.4759 | 1.5378 | 0.0575 | 0.3774 |
| 12-HpETE | 0.2342 | 1.5992 | 0.0580 | 2.0715 | 0.0464 | 1.7122 |
| 13-HODE | 2.3079 | 2.2778 | 0.3795 | 1.0629 | 0.0224 | 0.1973 |
| 13-HOTE | 2.7476 | NA | 0.3299 | NA | 0.0507 | NA |
| 13-HpODE | 0.1011 | 3.3147 | 0.0147 | 1.7941 | 0.0062 | 1.0341 |
| 13-KODE | 3.1858 | 1.1181 | 0.8815 | 0.5363 | 0.1388 | 0.3533 |
| 14,15-DiHETE | 1.3078 | NA | 1.2423 | NA | 0.4761 | NA |
| 14,15-DiHETrE | 1.4312 | NA | 1.1119 | NA | 0.0496 | NA |
| 14(15)-EpETE | 0.6282 | NA | 1.0151 | NA | 1.3536 | NA |
| 14(15)-EpETrE | 1.1728 | NA | 0.1362 | NA | NA | NA |
| 14-HDoHE | 2.0786 | NA | 0.5984 | NA | 0.4101 | NA |
| 15,16-DiHODE | 1.8821 | NA | 1.2190 | NA | 0.0387 | NA |
| 15(16)-EpODE | 2.4972 | NA | 0.3268 | NA | 0.0359 | NA |
| 15-deoxy PGJ2 | 0.8937 | NA | 1.6203 | NA | 0.5786 | NA |
| 15-HEPE | 1.3575 | 1.6780 | 0.6472 | 1.6841 | 0.4956 | 0.4314 |
| 15-HETE | 1.4331 | 3.2817 | 0.1689 | 1.2051 | 0.0170 | 0.1636 |
| 15-HETrE | 3.0597 | 1.4648 | 0.5690 | 0.7729 | 0.0309 | 0.2285 |
| 15-HpETE | 0.0912 | 3.2776 | 0.0350 | 1.3945 | 0.0195 | 1.3230 |
| 15-KETE | 1.6605 | NA | 0.8194 | NA | 0.6041 | NA |
| 16(17)-EpDPE | NA | NA | NA | NA | NA | NA |
| 17,18-DiHETE | 0.6330 | NA | 1.5850 | NA | 0.8905 | NA |
| 17(18)-EpETE | NA | NA | NA | NA | NA | NA |
| 17-HDoHE | 2.4943 | NA | 0.2490 | NA | 0.1315 | NA |
| 19,20-DiHDoPA | 0.8318 | NA | 1.3508 | NA | 0.9246 | NA |
| 19(20)-EpDPE | NA | NA | NA | NA | NA | NA |
| 20-carboxy-LTB4 | NA | NA | NA | NA | NA | NA |
| 20-HETE | NA | NA | NA | NA | NA | NA |
| 20-hydroxy-LTB4 | NA | NA | NA | NA | NA | NA |
| 4-HDoHE | NA | 0.4718 | NA | 0.9568 | NA | 1.4865 |
| 5,15-DiHETE | 1.7667 | NA | 0.6816 | NA | 0.3802 | NA |
| 5,6-DiHETrE | 2.1035 | NA | 0.1968 | NA | 0.0915 | NA |
| 5-HEPE | 1.9909 | NA | 0.5066 | NA | 0.3539 | NA |
| 5-HETE | 2.4131 | 0.7085 | 0.3072 | 0.8433 | 0.0967 | 1.3593 |
| 5-HpETE | 0.8998 | NA | 1.0481 | NA | 1.0145 | NA |
| 5-KETE | 2.1611 | 0.9417 | 0.3513 | 1.0612 | 0.0509 | 1.3669 |
| 6-keto PGF1a | 1.4833 | 0.6429 | 2.2834 | 0.7104 | NA | 0.0821 |
| 6-trans-LTB4 | 1.1309 | NA | 0.9640 | NA | 0.9084 | NA |
| 8,15-DiHETE | NA | NA | NA | NA | NA | NA |
| 8,9-DiHETrE | 1.8368 | NA | 0.6974 | NA | 0.2520 | NA |
| 8(9)-EpETrE | 0.5862 | NA | 1.3793 | NA | 1.0424 | NA |
| 8-HETE | 1.6282 | 0.5704 | 0.5972 | 1.4477 | 0.0840 | 1.4853 |
| 9,10-13-TriHOME | 1.2301 | 0.1431 | 4.2272 | 0.5604 | 0.0801 | 0.0422 |
| 9,10-DiHODE | 2.3986 | NA | 0.5340 | NA | 0.1815 | NA |
| 9,10-DiHOME | 3.5056 | 1.0863 | 0.8598 | 0.3405 | 0.3136 | 0.1549 |
| 9(10)-EpODE | 2.6538 | NA | 0.3787 | NA | 0.0966 | NA |
| 9(10)-EpOME | 3.2006 | 1.7488 | 0.4894 | 0.4756 | 0.1141 | 0.2286 |
| 9,12,13-TriHOME | 1.2912 | 0.1788 | 4.1430 | 0.5408 | 0.0823 | 0.0472 |
| 9-HEPE | NA | NA | NA | NA | NA | NA |
| 9-HETE | 0.7994 | 0.6142 | 0.2108 | 1.8696 | 0.1525 | 2.3324 |
| 9-HODE | 3.5394 | 1.0586 | 0.2104 | 0.3456 | 0.0317 | 0.3458 |
| 9-HOTE | 2.3733 | NA | 0.1902 | NA | 0.0364 | NA |
| 9-HpODE | 0.0355 | 4.0776 | 0.0042 | 1.1432 | 0.0004 | 0.5953 |
| 9-KODE | 3.6888 | 1.0624 | 0.6413 | 0.4834 | 0.0728 | 0.2855 |
| Lipoxin A4 | 2.3587 | NA | 0.6802 | NA | 0.0669 | NA |
| LTB4 | NA | NA | NA | NA | NA | NA |
| LTB5 | NA | NA | NA | NA | NA | NA |
| PGD2 | 1.1044 | 0.1761 | 3.8685 | 0.4200 | 0.5447 | 0.1583 |
| PGE1 | 0.8753 | NA | 1.8853 | NA | 0.3745 | NA |
| PGE2 | 1.5858 | 0.4749 | 2.9291 | 0.5003 | 0.4204 | 0.2748 |
| PGE3 | 0.5359 | NA | 1.6869 | NA | 0.9116 | NA |
| PGF2a | 2.8473 | 0.2415 | 2.1750 | 0.3002 | 0.3075 | 0.1471 |
| PGJ2/ d 12-PGJ2 | 1.2518 | NA | 1.2316 | NA | 0.5573 | NA |
| Resolvin D1 | NA | NA | NA | NA | NA | NA |
| Resolvin E1 | NA | NA | NA | NA | NA | NA |
| TXB2 | 1.3207 | NA | 1.7323 | NA | 0.0838 | NA |
Factors:
| F1 | Sample Type:Adipocyte | Timepoint:18 hours |
| F2 | Sample Type:Adipocyte | Timepoint:4 hours |
| F3 | Sample Type:Co-culture | Timepoint:18 hours |
| F4 | Sample Type:Co-culture | Timepoint:4 hours |
| F5 | Sample Type:Control | Timepoint:18 hours |
| F6 | Sample Type:Control | Timepoint:4 hours |
