Data for C2C12 stretch cessation models muscle atrophy and anaplerotic changes in metabolism (Study ST000431)

(Analysis AN000681)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7
1,3-Dihydroxyacetone 1.0110 0.9987 1.0012 1.0017 0.9850 1.0025 NA
2-Hydroxy-2-methylbutyric acid 0.9941 0.9997 0.9922 1.0072 1.0091 0.9974 NA
2-Hydroxybutyric acid 0.9940 1.0095 1.0008 1.0045 0.9951 0.9932 1.0052
2-Hydroxypyridine 1.1473 0.9790 0.9159 1.0332 0.9686 0.9072 1.0157
2-Isopropylmalic acid 0.9840 1.0218 0.9499 1.0039 1.0257 0.9869 1.0323
2-Ketoleucine 1.0336 0.9690 0.9902 1.0098 0.9743 0.9935 1.0316
2-Ketovaline 1.0487 0.9533 0.9846 1.0072 0.9585 0.9957 1.0535
5-Hydroxytryptophan 1.0790 0.9074 0.9015 0.9714 0.9115 0.9577 1.1065
Alanine 1.0244 0.9857 0.9904 1.0123 0.9760 0.9948 1.0182
alpha Ketoglutaric acid 1.0519 0.9598 0.9881 0.9999 0.9716 0.9756 1.0519
alpha-Monopalmitin 1.0080 0.9984 0.9981 1.0002 0.9881 1.0032 1.0028
alpha-Monostearin 1.0064 1.0016 0.9989 0.9988 0.9886 1.0052 0.9988
Aminomalonic acid 1.0015 1.0080 0.9858 1.0028 0.9880 0.9879 1.0299
Arginine/Citrulline 1.0304 0.9913 0.9977 1.0113 0.9852 1.0190 0.9588
Asparagine 1.0497 0.9664 0.9861 1.0013 0.9598 0.9927 1.0464
Aspartic acid 1.0267 0.9961 0.9509 1.0213 0.9708 0.9790 1.0622
Benzoic acid 1.0020 0.9978 1.0066 1.0012 0.9943 0.9869 1.0157
beta-Alanine 1.0416 1.0304 0.9884 0.7670 1.0312 1.0234 1.0230
beta-Monopalmitin 1.0027 0.9993 0.9903 1.0132 0.9961 0.9570 1.0557
beta-Monostearin 1.0074 1.0075 0.9891 0.9971 0.9817 1.0052 1.0104
C10 hydrocarbon 1.0178 0.9992 1.0231 0.9965 0.9389 1.0259 0.9898
C11 hydrocarbon 0.9606 1.0545 0.9801 0.9955 1.0301 0.9570 1.0365
C12 hydrocarbon 0.9823 1.0013 1.0113 0.9988 0.9781 1.0014 1.0263
C13 hydrocarbon 1.0043 1.0047 1.0063 0.9994 0.9907 0.9987 0.9964
C15 hydrocarbon 1.0152 NA 1.0102 1.0072 NA 1.0321 0.9550
C22 hydrocarbon 1.0122 1.0305 1.0053 0.9657 0.9855 0.9998 0.9852
Citric acid/isocitric acid 1.0524 0.9674 0.9710 0.9996 0.9349 0.9767 1.1059
Cysteine 1.0227 0.9695 0.9900 1.0052 0.9618 1.0177 1.0272
Cysteinesulfinic acid 0.9943 1.0305 0.9955 NA 1.0523 0.9903 0.9595
Cystine 1.0103 0.9949 0.9923 0.9971 0.9971 1.0019 1.0058
Dehydroascorbic acid� 1.0070 0.9777 1.0001 1.0216 0.9912 1.0268 0.9665
deuterated Myristic Acid (RTL std) 1.0018 0.9982 0.9985 1.0005 0.9973 1.0010 1.0023
Dodecamethylpentasiloxane 1.0329 0.9787 1.0018 1.0327 0.9904 0.9392 1.0446
epsilon-Caprolactam 1.0648 0.9609 0.9806 0.9656 0.9634 0.9925 1.0511
Erythronic acid/threonic acid 1.0278 0.9812 0.9744 0.9889 0.9740 0.9970 1.0428
Ethanolamine 1.0309 0.9768 0.9906 0.9910 0.9686 1.0090 1.0301
Ethylmalonic acid 1.0045 0.9839 1.0108 1.0112 0.9944 1.0121 0.9630
Fructose or similar ketohexose 1.0137 0.9773 1.0005 0.9944 1.0348 0.9968 0.9836
Fumaric acid 1.0645 0.9405 0.9779 0.9748 0.9178 0.9850 1.1447
Gentisic acid 1.0262 0.9755 0.9583 1.0086 0.9963 1.0333 NA
Gluconic acid or similar sugar acid 1.0178 1.0007 1.0101 1.0101 1.0023 1.0098 0.9459
Glucose and other aldohexoses 1 1.0015 0.9968 0.9956 0.9995 1.0003 1.0066 0.9976
Glucose and other aldohexoses 2 1.0022 0.9975 0.9987 1.0003 1.0010 1.0073 0.9906
Glucose and other aldohexoses 3 1.0013 1.0071 0.9721 1.0020 1.0086 0.9914 1.0203
Glutamic acid 1.0134 0.9916 0.9976 1.0003 0.9938 1.0007 1.0023
Glutamine 1.0033 0.9976 1.0000 0.9978 0.9991 1.0039 0.9970
Glyceric acid NA NA NA NA NA NA 1.0000
Glycerol 0.9936 1.0244 1.0277 0.9749 1.0187 1.0042 0.9551
Glycine 1.0127 0.9929 0.9950 0.9971 0.9867 1.0014 1.0138
Glycolic acid 1.0524 0.9772 0.9834 0.9785 0.9845 0.8914 1.0784
Glyoxylic acid NA 0.9982 1.0135 0.9859 1.0056 NA 0.9913
Guanine 1.0681 NA NA 0.9083 NA 1.0177 NA
Heptadecanoic acid/Octadecanol NA NA 1.0521 0.9823 0.9817 NA 1.0383
Hexacosemethyldodecasiloxane NA 0.9517 1.0618 1.0114 0.9819 0.9551 1.0599
Hexitols 1.0018 0.9994 1.0000 1.0005 0.9952 1.0012 1.0016
Hexose-6-phosphate 0.9327 0.9332 0.9755 1.0117 1.0356 1.0536 1.0422
Histidine 1.0116 0.9968 0.9954 0.9976 0.9919 1.0017 1.0045
Hydroquinone 1.0046 0.9917 0.9819 1.0018 0.9618 1.0079 1.0601
Hydroxyprolines 1.0131 0.9679 0.9605 1.0194 1.0697 1.0026 1.0400
Hypoxanthine 1.0643 1.0236 0.9612 1.0038 NA 0.9713 NA
Isoleucine 1.0088 0.9967 0.9986 0.9957 0.9959 1.0022 1.0014
Isomaltose or similar disaccharide 1.0101 0.9871 0.9930 0.9981 0.9952 1.0046 1.0103
Lactic acid 1.0162 0.9831 0.9906 1.0049 0.9804 0.9905 1.0375
Lactose or similar disaccharide 1.0219 0.9812 1.0016 0.9975 0.9926 1.0040 NA
Leucine 1.0108 0.9972 0.9933 0.9990 0.9921 1.0010 1.0063
Lysine 1.0092 0.9980 0.9976 0.9969 0.9955 1.0043 0.9970
Malic acid 1.0538 0.9665 0.9837 1.0087 0.9414 0.9753 1.0789
Malonic acid 0.9951 1.0027 1.0172 0.9812 1.0196 0.9868 1.0018
Maltose or similar disaccharide 1.0157 1.0001 1.0038 0.9963 0.9785 1.0135 0.9875
Methionine 1.0140 0.9916 0.9969 0.9967 0.9931 1.0088 0.9960
Methionine sulfoxide 1.0040 1.0213 1.0419 0.9596 0.9865 0.9815 1.0051
Methyl stearate 1.0158 1.0547 0.9957 1.0161 0.9733 0.9644 NA
MSTFA artifact 1.0223 1.0147 0.9955 1.0107 0.9481 1.0290 0.9750
Myoinositol 1.0029 0.9966 0.9959 0.9999 0.9981 1.0036 1.0017
Myristic acid or Pentadecanol 0.9692 0.9778 1.0089 1.0424 1.0357 0.9722 1.0058
Nicotinamide 1.0360 0.9761 0.9988 1.0229 0.9879 1.0174 0.9747
Ornithine 1.0151 0.9740 0.9897 0.9989 1.0011 0.9942 1.0291
Palmitic acid 1.0198 1.0029 1.0035 0.9819 0.9800 1.0101 0.9984
Pantothenic acid 1.0014 1.0043 0.9844 0.9978 0.9992 1.0064 1.0044
Pentitols 1.0980 0.8933 0.9534 0.9707 0.9186 0.9976 1.1335
Phenylalanine 1.0129 0.9924 0.9959 0.9987 0.9946 1.0047 0.9992
Phosphoric acid 0.9962 0.9797 1.0107 1.0092 1.0078 0.9850 1.0190
Proline 1.0576 0.9526 0.9701 1.0021 0.9251 0.9961 1.0976
Putrescine 0.9662 0.9729 0.9877 1.0019 0.9770 0.9576 1.1051
Pyridoxine 1.0133 0.9950 0.9428 1.0309 0.9952 1.0006 1.0220
Pyruvic acid 0.9851 1.0139 1.0114 1.0097 1.0160 1.0023 0.9607
Sedoheptulose or similar sugar 1.0099 0.9977 0.9988 0.9975 0.9974 1.0055 0.9913
Serine 1.0115 1.0041 1.0069 0.9962 1.0035 1.0091 0.9657
Stearic acid 1.0100 1.0015 1.0030 0.9950 0.9874 1.0033 0.9986
Succinic acid 1.0051 0.9976 0.9996 0.9999 0.9643 0.9878 1.0321
Succinylacetone 1.0041 0.9984 1.0111 0.9672 0.9950 1.0137 NA
Sucrose and similar disaccharides 0.9199 1.0164 0.9172 1.0264 1.0427 1.0488 0.9931
Sulfuric acid 1.0184 1.0965 0.9643 0.8983 NA 1.0978 NA
Tetracosamethylundecasiloxane 0.9456 1.0497 0.9168 NA 1.0925 NA NA
Threitol/erythritol 1.0141 NA 0.9591 0.9674 NA 0.9994 1.0220
Threonine 1.0102 0.9964 0.9991 0.9978 0.9961 1.0021 0.9976
Threose/erythrose 1.0016 1.0074 0.9605 1.0452 1.0472 0.9842 0.9962
Tryptamine/Norepinephrine 1.0352 0.9905 1.0080 0.9938 0.9758 1.0103 0.9744
Tryptophan 1.0156 0.9861 0.9872 0.9947 0.9866 1.0093 1.0175
Tyrosine 1.0116 0.9953 0.9962 0.9979 0.9960 1.0034 0.9985
Unoximated aldohexose NA NA NA NA NA NA 1.0000
Valine 1.0096 0.9954 0.9869 0.9998 0.9821 1.0074 1.0162
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Factors:

F1Group:12 hour reversal
F2Group:1 hour reversal
F3Group:3 hour reversal
F4Group:6 hour reversal
F5Group:6 hour stretch
F6Group:no stretch-serum free
F7Group:serum-no stretch
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