Data for Maternal Hypoxemia and oxidative stress in the fetus, newborn, and adult. exercise training for peripheral artery disease (Study ST000872)

(Analysis AN001404)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15
11_12-DiHETrE	0.6427	0.6723	3.3926	2.2328	1.7759	0.8131	2.6382	1.4116	1.6913	0.3511	0.3012	0.2903	0.2591	0.3259	0.2092
11(12)-EpETE	0.6398	0.4550	1.3548	1.5772	0.5779	0.4147	5.2366	0.7226	1.4092	0.6192	0.6178	0.9777	0.7296	0.5522	0.8709
11(12)-EpETrE	0.8524	0.7272	1.1406	1.2199	1.5682	0.6865	2.9781	1.4893	1.9260	0.7738	0.6049	0.7195	0.3369	0.2361	0.2935
11-HETE	0.2768	0.2863	0.6764	0.7582	1.0925	0.4290	0.8862	0.8026	0.6655	1.4694	3.1546	1.3780	2.2085	0.1491	0.0990
12_13-DiHODE	0.5713	0.9966	4.8615	2.7555	1.7812	0.9318	4.1124	0.7132	1.1830	0.0463	0.0659	0.0726	0.1709	0.0988	0.2102
12_13-DiHOME	1.1030	1.8671	2.0054	1.1978	4.0107	2.3339	1.5494	1.0346	2.0630	0.0765	0.0905	0.1200	0.1165	0.1195	0.1283
12(13)-Ep-9-KODE	0.6284	1.4662	3.5832	1.7786	1.5124	0.4893	4.8806	1.7046	0.9655	0.3341	0.2437	0.3657	0.4073	0.2883	0.2971
12(13)-EpODE	0.6196	1.2700	2.5221	2.6448	0.8696	0.7120	4.2173	1.0631	1.2499	0.0454	0.0485	0.1488	0.1671	0.0725	0.1892
12(13)-EpOME	2.8570	1.2958	0.8412	0.6418	1.4964	1.6363	1.0185	4.0352	1.2399	0.0420	0.0705	0.0438	0.0374	0.1367	0.1509
12-HEPE	0.0873	0.0513	0.1416	7.8001	0.2142	0.0512	0.5338	0.5158	0.0839	0.0368	0.0083	0.2891	0.8203	0.0524	0.5421
12-HETE	0.2701	0.1569	0.1154	5.2405	0.6663	0.1874	0.3910	1.7164	0.1914	0.2654	0.0879	0.6673	2.3081	0.5426	0.4540
13-HODE	0.9402	1.6815	1.7038	2.1255	2.1759	1.8732	1.5712	0.6237	1.4397	0.2559	0.2530	0.3770	0.3936	0.2553	0.3273
13-HOTE	0.6207	1.3800	4.0143	3.2834	1.6283	1.1302	2.7712	0.4572	1.1677	0.0200	0.0200	0.0389	0.0366	0.0876	0.2146
13-KODE	0.9957	0.9267	2.2505	1.2095	2.6166	2.2340	2.6192	1.0587	1.5112	0.3305	0.5194	0.3441	0.5874	0.2803	0.4895
14_15-DiHETE	0.2504	0.2638	5.0148	2.8686	0.7881	0.1639	8.5802	0.6277	0.7926	0.0757	0.0604	0.2847	0.0870	0.0905	0.2715
14_15-DiHETrE	0.5521	0.5653	4.5194	2.2718	2.3590	0.8243	3.5520	1.2560	1.7069	0.1768	0.1665	0.1828	0.1428	0.2413	0.1863
14(15)-EpETrE	0.9012	0.5640	1.5716	1.7297	4.2422	0.8088	2.5693	1.4463	1.7820	0.5066	0.2375	0.3945	0.2728	0.5759	0.4546
14-HDoHE	0.1291	0.2749	0.5902	6.4537	0.1318	0.2165	1.0267	0.2540	0.5984	0.0699	0.0357	0.3350	0.5783	0.1430	0.2049
15_16-DiHODE	0.9218	1.0756	4.6561	2.1689	2.7937	1.1600	3.6841	0.7237	1.3261	0.0566	0.0915	0.1462	0.1627	0.1304	0.2197
15(16)-EpODE	0.5315	1.2100	3.6362	2.1811	2.4450	1.3029	5.4674	0.6611	1.3787	0.0412	0.0719	0.0871	0.1240	0.0842	0.2008
15-deoxy PGJ2	1.0621	0.7244	0.5547	1.1706	0.3885	0.8745	0.8239	0.7679	1.1942	1.0468	1.1776	1.4947	0.7126	0.5942	1.0676
15-HEPE	0.4096	0.5872	1.4659	2.6146	0.5983	0.4639	2.8616	0.4994	0.6182	0.6453	0.3608	1.7254	1.1329	0.6842	1.2362
15-HETE	0.4811	0.4755	0.5541	1.0029	1.1576	0.7092	1.4683	0.8521	0.8166	1.1362	2.4380	1.1472	1.5963	0.7341	0.4079
15-Keto PGE2	0.7587	1.1416	1.6142	1.1619	0.2266	1.5844	0.8400	0.7515	0.9191	0.8697	1.2232	0.6465	1.3472	0.8104	0.7970
17_18-DiHETE	0.1669	0.2382	5.1028	3.3913	0.6587	0.2746	7.2223	0.7935	0.7073	0.0926	0.1060	0.3593	0.4290	0.0731	0.3316
17-HDoHE	0.4864	0.5614	2.2555	3.5899	0.6779	0.5789	1.6700	0.2473	0.5869	0.5173	0.6268	0.8744	0.4633	0.5685	1.3701
19_20-DiHDoPE	0.2420	0.3077	4.8153	3.3891	0.8360	0.2872	4.6820	0.7848	0.9148	0.2436	0.2966	0.4329	0.4469	0.1535	0.3415
19(20)-EpDPE	0.2927	0.3014	4.0160	3.2544	1.2465	0.3108	4.3499	0.8070	0.9877	0.2430	0.5165	0.4471	0.7883	0.1103	0.1290
20-HETE	0.3918	0.2818	2.1900	1.3176	2.0474	0.8643	5.5044	1.4082	1.2662	0.3889	1.1045	0.5594	0.8008	0.6948	0.5650
4-HDoHE	0.5845	0.8453	0.5122	2.5625	3.2759	0.6889	1.5607	0.5413	0.8435	0.5219	0.5161	1.1381	0.8681	1.0670	0.9141
5_6-DiHETrE	0.5585	0.4239	2.4333	2.5913	2.7492	0.7507	4.0275	1.4560	1.7087	0.0588	0.0546	0.0494	0.0708	0.2019	0.0739
5-HEPE	0.3608	0.6344	1.2658	4.2635	1.1259	0.5697	3.0706	0.6182	0.9660	0.1210	0.1278	0.2520	0.2918	0.1403	0.5115
5-HETE	0.7804	1.0185	1.2160	3.1299	3.6065	0.8495	1.5678	0.8266	1.2777	0.3005	0.0946	0.5637	0.5441	0.2872	0.2138
5-KETE	0.9102	0.9304	0.2668	3.0580	1.7075	0.9249	0.7020	0.4629	1.0478	0.6447	0.3818	0.9771	0.3066	0.3451	0.9221
8_9-DiHETrE	0.4216	0.3462	4.8488	3.2760	1.6723	0.4398	3.7851	0.9321	1.6048	0.0917	0.0823	0.1033	0.0961	0.0872	0.0651
8-HETE	0.5019	0.4803	2.0331	1.9077	2.0791	0.8946	3.4753	1.3415	1.5884	0.5052	0.6077	0.4174	0.3538	0.2691	0.2476
9_10-DiHODE	0.4000	0.7293	5.6089	2.8782	1.3186	0.6801	5.1631	0.9639	1.2014	0.0229	0.0379	0.0732	0.0981	0.0679	0.2387
9_10-DiHOME	0.8917	1.4404	2.5798	1.4660	2.8392	1.5742	2.4205	1.4339	1.9137	0.1117	0.0894	0.1935	0.4981	0.1392	0.1615
9_10-e-DiHO	1.1047	1.0498	1.9267	1.6448	1.4004	1.2536	1.5859	1.7157	1.3882	0.3805	0.3089	0.4187	1.0058	0.3464	0.4527
9(10)-EpO	3.2218	0.2049	0.2447	1.0969	0.3026	0.3699	0.3064	8.4191	0.2983	0.1426	0.1630	0.1259	0.2330	0.1931	0.1579
9(10)-EpODE	0.5933	1.3384	2.5972	2.6467	1.3047	0.8448	4.8885	0.9320	1.3282	0.0627	0.0836	0.1025	0.0984	0.1653	0.3922
9(10)-EpOME	3.7305	0.5001	0.5391	0.5045	1.4846	0.6333	1.7404	6.1138	0.7065	0.0473	0.0807	0.0601	0.0578	0.0962	0.1092
9-HEPE	0.3824	0.7055	2.5974	3.7945	1.2337	0.4640	2.3766	0.6031	0.8259	0.3107	0.2429	0.3732	0.7780	0.4274	0.7824
9-HETE	0.9507	1.3426	1.0775	2.2129	3.2275	0.4278	2.7907	0.6494	0.4613	0.7915	0.3523	1.4796	0.8910	0.7191	0.2401
9-HODE	0.9333	1.5773	1.5782	1.9494	2.1558	1.5777	1.9012	0.7996	1.4291	0.3149	0.3687	0.4875	0.5522	0.1823	0.2907
9-HOTE	0.4510	1.0797	3.0806	3.4810	1.4118	1.0117	3.8529	0.5246	0.9917	0.0340	0.0296	0.0664	0.0920	0.1925	0.5535
9-KODE	0.8145	1.6119	1.7485	2.1832	2.1194	1.6305	2.7202	1.2521	1.6565	0.1182	0.1460	0.1158	0.1726	0.1094	0.2416
PGE2	0.1269	0.2594	0.1845	0.2695	1.1729	1.2298	0.8287	1.2453	1.2800	0.7406	5.1319	0.5487	1.2265	0.2354	0.0262
PGF2a	0.2886	0.4404	0.5700	0.3336	0.4781	0.8973	0.5167	1.0481	0.7230	1.1955	2.3179	1.2117	2.3058	0.6970	0.1306
SUM-TriHOME	2.8615	0.6674	0.6780	1.3681	0.4603	1.0881	0.5876	3.4349	0.5647	0.3421	0.3831	0.3777	0.5008	0.5180	0.6384
TXB2	0.2618	0.2874	0.7947	3.6736	0.2805	0.1762	0.2666	0.4427	0.3230	0.8832	0.3957	1.1556	2.4567	1.4018	0.5298

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Factors:

F1	Life stage:Adult | Pregnancy status:Non-pregnant | Treatment group:Hypoxic | Sample origin:Arterial
F2	Life stage:Adult | Pregnancy status:Non-pregnant | Treatment group:Hypoxic | Sample origin:Venous
F3	Life stage:Adult | Pregnancy status:Non-pregnant | Treatment group:Normoxic | Sample origin:Arterial
F4	Life stage:Adult | Pregnancy status:Non-pregnant | Treatment group:Normoxic | Sample origin:Venous
F5	Life stage:Adult | Pregnancy status:Pregnant | Treatment group:Hypoxic | Sample origin:Arterial
F6	Life stage:Adult | Pregnancy status:Pregnant | Treatment group:Hypoxic | Sample origin:Venous
F7	Life stage:Adult | Pregnancy status:Pregnant | Treatment group:Normoxic | Sample origin:Venous
F8	Life stage:Adult | Pregnancy status:Unknown | Treatment group:Hypoxic | Sample origin:Arterial
F9	Life stage:Adult | Pregnancy status:Unknown | Treatment group:Hypoxic | Sample origin:Venous
F10	Life stage:Fetus | Pregnancy status:- | Treatment group:Hypoxic | Sample origin:Arterial
F11	Life stage:Fetus | Pregnancy status:- | Treatment group:Hypoxic | Sample origin:Venous
F12	Life stage:Fetus | Pregnancy status:- | Treatment group:Normoxic | Sample origin:Arterial
F13	Life stage:Fetus | Pregnancy status:- | Treatment group:Normoxic | Sample origin:Venous
F14	Life stage:Newborn | Pregnancy status:- | Treatment group:Hypoxic | Sample origin:Venous
F15	Life stage:Newborn | Pregnancy status:- | Treatment group:Normoxic | Sample origin:Venous