Metabolite Reference Standards and Reagents:

(6R)-5,10-methylenetetrahydrofolate

Compound Nomination ID74
Common Name(6R)-5,10-methylenetetrahydrofolate
IUPAC Name2-({4-[(6aR)-3-amino-1-oxo-1H,2H,5H,6H,6aH,7H,8H,9H-imidazolidino[1,5-f]pteridin-8-yl]phenyl}formamido)pentanedioic acid
InChiKeyQYNUQALWYRSVHF-OLZOCXBDSA-N
Isotopic Label TypeC-13
Synonyms1. (6R)-5,10-methylenetetrahydrofolate 2. 5,10-Methenyltetrahydropteroylglutamate 3. 5,10-Methylene-6-Hydrofolate 4. 5,10-Methylene-6-Hydrofolic acid 5. 5,10-Methylene-THF 6. 5,10-Methylenetetrahydrofolate 7. 5,10-Methylenetetrahydrofolic acid 8. N5>,N10-methylenetetrahydrofolate
PubChem ID445117
Metabolite Standards Synthesis Core (MSSC)RTI
Statussynthesis in process 

(6R)-5,10-methylenetetrahydrofolate has the following unlabelled parent compound

Compound Nomination ID174
Common Name(6R,S)-5,10-Methylene-5,6,7,8-tetrahydrofolic acid, calcium salt
IUPAC Name(2S)-2-[[4-[(6aR,S)-3-amino-1-oxo-2,5,6,6a,7,9-hexahydroimidazo[1,5- f]pteridin-8-yl]benzoyl]amino]pentanedioic acidhexahydroimidazo[1,5-f]pteridin-8-yl)benzoyl]amino]pentanedioic acid
InChiKeyAKUPTUNGFOADRT-ZEDZUCNESA-L
Isotopic Label Typeunlabelled parent
Synonyms(6R)-5,10-Methylenetetrahydrofolate calcium salt
PubChem ID108194
Metabolite Standards Synthesis Core (MSSC)RTI
Report5_10-methylene_tetrahydrofolic_acid_documentation.zip
Statuscompleted *

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(6R)-5,10-methylenetetrahydrofolate was approved for synthesis based on the following nomination:


Compound Nomination ID40
Common Name10-Formyl-tetrahydrofolic acid
IUPAC Name(2S)-2-[(4-{N-[(2-amino-4-oxo-1,4,5,6,7,8-hexahydropteridin-6-yl)methyl]formamido}phenyl)formamido]pentanedioic acid
InChiKeyAUFGTPPARQZWDO-YUZLPWPTSA-N
SynonymsN-[p-[N-[(2-Amino-5,6,7,8-tetrahydro-4-hydroxy-6-pteridinyl)methyl]formamido]benzoyl]-Glutamate N10-Formyltetrahydropteroylglutamate
PubChem ID122347
Metabolite Standards Synthesis Core (MSSC)RTI
ReportFinal_SynRpt_10-formyltetrahydrofolate__160825-kga.pdf
Statuscompleted

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* This non-target unlabelled compound was analyzed by chromatographic and spectral methods as appropriate but was not certified by GLP protocols.
 One of more compounds were approved for synthesis based on this nomination. Click the common name for details.
 This compound was approved for synthesis based on the nomination of a different compound, or a nomination that was not specific.

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