Labeled 13C_EV_2h_neg_1 13C_EV_2h_neg_2 13C_EV_2h_neg_3 13C_EV_6h_neg_1 13C_EV_6h_neg_2 13C_EV_6h_neg_3 13C_EV_24h_neg_1 13C_EV_24h_neg_2 13C_EV_24h_neg_3 13C_Cre_2h_neg_1 13C_Cre_2h_neg_2 13C_Cre_2h_neg_3 13C_Cre_6h_neg_1 13C_Cre_6h_neg_2 13C_Cre_6h_neg_3 13C_Cre_24h_neg_1 13C_Cre_24h_neg_2 13C_Cre_24h_neg_3 Ketovaline 2086469837 2025179793 1894817751 3094396715 3107754538 2901470234 4691828984 4278649388 4316237833 1440618278 1361474534 1546279407 2316530265 2392148775 2512793133 3423071325 3374641004 3827169663 Exchange Rate [%]: 0 8.738697028 8.424827097 7.949116004 8.282411166 6.942623789 7.878551337 15.62140802 26.99918349 13.23553486 6.838917169 8.55415412 8.770634999 7.09393852 6.188315131 6.48873818 11.55192461 10.72945614 11.58505604 Exchange Rate [%]: 1 0 0 0 0 0 0 0.3531601 0 0 0 0 0 0.073589521 0 0 0 0.016030755 0 Exchange Rate [%]: 2 0 0.023027127 0.007110023 0.025825689 0.014341488 0.028591096 0.118250256 0.061404666 0.041748595 0.007835343 0 0 0.008611564 0.01953999 0.014303728 0.019517649 0.04194577 0.023341339 Exchange Rate [%]: 3 0.198939814 0.202399976 0.317880113 0.210938021 0 0.19555683 0.331469602 0 0.234608512 0.137206619 1.83241E-06 0.133307243 0.259780844 0.191982533 0.242667057 0.154848661 0.264107014 0.255640526 Exchange Rate [%]: 4 3.663769275 3.259455604 3.458226891 3.742995571 4.895983578 3.349746012 3.02416197 2.075150784 2.702850368 3.197386701 2.601717116 3.130481897 4.198190072 2.83688782 3.475235152 2.463739067 3.821311237 3.396886367 Exchange Rate [%]: 5 87.39859388 88.0902902 88.26766697 87.73782955 88.14705114 88.54755472 80.55155005 70.86426106 83.78525767 89.81865417 88.84412693 87.96557586 88.36588948 90.76327453 89.77905588 85.80997001 85.12714909 84.73907573 Ketoleucine 4788649682 4263002771 4049584214 5711478602 5237983575 5483016870 4302033184 4379588034 4307812180 3423643268 2636322305 2970172606 4184787949 4273791559 4894389091 3483963554 4004149153 4410182757 Exchange Rate [%]: 0 6.660898316 6.263087414 4.938511088 8.751694472 9.276616793 8.275849495 26.77693206 20.38490507 22.49055517 5.619338566 7.070270343 5.663848595 7.748269831 6.992822611 6.965720956 18.31843066 17.15604143 14.98586521 Exchange Rate [%]: 1 0 0 0.046829972 0 0.033064631 0 0 0.3579803 0 0 0 0.01893535 0.064192165 0 0 0.160074541 0 0.223610572 Exchange Rate [%]: 2 0.097790051 0.145221871 0.125167843 0.13083379 0.188637512 0.136331803 0.259648376 0.218965047 0.191745682 0.087442248 0.128675247 0.123075086 0.14955817 0.136344123 0.119745315 0.239211313 0.224576182 0.224126724 Exchange Rate [%]: 3 0 0 0 0 0 0 0.000476063 0 0 0 0 0 0 0 0 0 0 0 Exchange Rate [%]: 4 0.113922667 0.129673083 0.117329094 0.122962246 0.131893776 0.141181185 0.154535451 0.094520485 0.096275617 0.116209567 0.134195865 0.139139631 0.174172392 0.130513086 0.170208034 0.133345045 0.114507398 0.131290561 Exchange Rate [%]: 5 4.790495791 5.460049217 4.396852071 3.891091082 5.342390646 4.564335992 3.692616933 2.935100759 3.585066007 3.7651961 4.709607311 4.891672251 4.898678626 4.707877247 4.669855322 4.712576554 4.143088096 4.96955784 Exchange Rate [%]: 6 88.33689317 88.00196842 90.37530993 87.10341841 85.02739664 86.88230153 69.11579112 76.00852834 73.63635753 90.41181352 87.95725123 89.16332909 86.96512882 88.03244293 88.07447037 76.43636189 78.36178689 79.46554909 Ketoisoleucine 1897492038 2673251145 2361685537 2806303513 3574926561 2345056395 2398164975 1964590610 1972700823 1289008399 1537861109 1799292423 2309412642 2514861777 2131248031 2909911057 2180277673 3013763275 Exchange Rate [%]: 0 6.230805981 6.234223027 6.28222098 10.72338461 5.60027386 7.29165743 20.96650111 36.01537921 30.56885577 5.894763047 5.309428335 5.616294717 5.859848082 6.718048026 6.385841058 14.21034225 14.58692671 23.43481606 Exchange Rate [%]: 1 0.149453772 0 0 0 0 0.003536038 1.504311441 0 0 0 0 0 0 0 0.000894578 0 0.110911713 0 Exchange Rate [%]: 2 0.174040401 0.07984751 0.087208812 0.154340541 0.073668494 0.198143198 0.177060489 0.338446082 0.423138185 0.198592157 0.119229541 0.105407667 0.097278015 0.160620823 0.147418357 0.201374242 0.23746972 0.177942709 Exchange Rate [%]: 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Exchange Rate [%]: 4 0.144942745 0.101527309 0.134162299 0.165577541 0.148833091 0.146629533 0.077478096 0.167617758 0.153247513 0.124001507 0.127212519 0.102221059 0.085166204 0.152216578 0.116449128 0.127125772 0.197882715 0.098469192 Exchange Rate [%]: 5 4.591794806 3.101466698 4.811166298 6.055823955 3.263886195 4.534862155 3.797636613 5.357175611 4.323616115 5.832335819 4.76368899 4.72155577 3.890814224 4.654075575 4.67616567 2.885369466 4.190854764 2.335595279 Exchange Rate [%]: 6 88.7089623 90.48293546 88.68524161 82.90087336 90.91333836 87.82517165 73.47701225 58.12138134 64.53114241 87.95030747 89.68044062 89.45452079 90.06689348 88.315039 88.67323121 82.57578827 80.67595438 73.95317676 3-Hydroxyisobutyric acid 16745107.63 16128921.74 15273383.48 38070509.53 38173520.43 35710865.17 109394908 102838244.2 103983644.1 8690400.674 8118187.883 8895428.176 19786216.96 20214717.24 21437597.61 67728374.99 67743582.09 75605178.47 Exchange Rate [%]: 0 28.25603898 29.42719455 29.82598675 13.68677771 13.14442182 13.0674269 10.1784965 10.18792439 9.451587738 32.83616329 31.06382059 28.24708704 15.15392951 13.67090544 13.47867207 11.88729199 12.4108108 12.15651041 Exchange Rate [%]: 1 0 0 0.082847168 0 0.018305777 0 0 0 0 0 0 0.025100547 0.002261432 0.020562516 0.082769546 0 0.018898819 0 Exchange Rate [%]: 2 0.286437458 1.77596E-06 0.278339886 0.326283213 0.250332366 0.312902438 0.312575871 0.27235554 0.310980567 0.200269225 0.285261961 0.249528971 0.251162807 0.293192302 0.310426562 0.311865054 0.303810733 0.305067404 Exchange Rate [%]: 3 2.17729408 2.211743686 1.967424826 2.682672088 2.540022065 2.891067861 2.939367046 3.057246476 2.935189771 2.083066569 2.115141913 2.040894592 2.618308052 2.808392913 2.735780926 2.85698829 2.900254655 2.886169676 Exchange Rate [%]: 4 69.28022948 68.36105999 67.84540137 83.30426699 84.04691797 83.7286028 86.56956058 86.4824736 87.30224192 64.88050091 66.53577553 69.43738885 81.9743382 83.20694683 83.39235089 84.94385466 84.36622499 84.65225251 Succinate 25592024.38 24658703.23 23814563.02 30375911.33 30564793.34 29895964.19 44798475.48 43891012.44 42418840.17 15681248.61 15770072.72 16199349.74 19026150.66 20572391.79 20566873.77 25810672.61 25673055.76 26263290.03 Exchange Rate [%]: 0 78.42261318 80.60637079 78.27486972 79.38467899 78.92517665 78.73140818 85.27007781 84.97650597 84.28788569 76.14769137 74.73909366 75.12828473 75.37400432 75.72862737 76.01150875 87.65071031 85.77779687 85.24606755 Exchange Rate [%]: 1 4.514608666 4.48665565 4.77068776 5.193029007 5.793326333 5.173007315 5.632603519 5.696609484 5.853992746 4.939114106 5.09662373 5.381088324 6.004527157 6.222379075 6.102786397 5.262592999 5.450164709 5.745021911 Exchange Rate [%]: 2 12.64172664 12.6206686 12.13398826 12.46763563 12.27611524 12.10699482 7.310268919 7.571771357 7.831245672 13.89769827 13.90490154 14.72799216 13.67766925 13.538095 13.78899848 6.918163939 6.7593394 7.010913559 Exchange Rate [%]: 3 4.133017933 2.017083326 4.580901159 2.684641749 2.693794897 3.723456071 1.787049747 1.616090902 1.804976353 4.748142435 5.940069259 4.51464216 4.663552288 4.1886566 3.695930435 0.015614529 1.873492648 1.831940144 Exchange Rate [%]: 4 0.28803358 0.269221632 0.239553097 0.270014623 0.311586886 0.265133609 0 0.139022291 0.221899537 0.267353819 0.319311807 0.247992625 0.280246988 0.322241954 0.400775937 0.152918219 0.139206374 0.166056835 Acetoacetate 62032971.96 65107017.27 67543363.59 60655694.95 79902598.57 61961832.95 59884222.09 97629881.3 59496943.42 54756398.64 30892806.03 28285050.96 37237393.98 43760942.82 42297215.73 53989886.83 64695233.09 38077955.49 Exchange Rate [%]: 0 84.81097527 76.11961271 74.17878221 81.47716559 79.02250472 81.90994719 89.42507846 91.7421271 79.55241983 78.94476241 76.32009891 76.0145994 74.76258253 85.01721448 76.44697597 86.83797251 91.55773672 87.23582247 Exchange Rate [%]: 1 4.665383638 6.30538604 7.44555799 4.083775749 3.890456562 4.243699664 4.042566071 2.649903808 10.58436712 4.495099519 7.545485184 7.433300203 9.792470008 2.905658869 8.204397993 6.244754046 4.241177477 5.98723694 Exchange Rate [%]: 2 9.495090225 15.99223454 16.79815912 13.27473494 16.17165548 12.75311499 6.403412594 5.328042659 9.232600472 15.05576567 14.800462 15.34243679 14.43843788 10.91551368 14.20449512 6.774951736 4.074679662 6.575198929 Exchange Rate [%]: 3 0.99363192 1.582766709 1.577500676 1.150546399 0.915383238 1.046621511 0.128942878 0.279926429 0.630612577 1.504372393 1.225680193 1.160306886 0.951722882 1.069540643 1.144130913 0.142321709 0.126406147 0.201741661 Exchange Rate [%]: 4 0.034918945 0 0 0.013777317 0 0.046616652 0 0 0 0 0.108273716 0.049356724 0.054786704 0.092072321 0 0 0 0 Oxoglutarate 34565607.03 38355318.76 37208024.12 49318358.12 57853630.88 54681916.69 92434800.15 74204969.7 82893385.03 18908662.59 19966286.38 18752161.3 26198083.01 30376928.24 26236613.64 43391288.43 43508131.57 40649782.57 Exchange Rate [%]: 0 77.13819295 78.46448965 78.3390853 78.25662379 78.97808466 78.19628803 85.36645954 84.78003891 83.69836561 75.22141254 74.19705669 73.84710629 73.23135889 73.94853533 73.16512694 85.94152547 84.04241952 86.33077838 Exchange Rate [%]: 1 5.469307928 5.072630497 5.164634018 5.881166192 6.088735782 5.89565789 5.960557222 6.171762761 6.546592932 5.720855425 6.265589292 6.116584511 7.473245041 6.907881261 7.627620568 6.001577658 7.226780856 5.791047354 Exchange Rate [%]: 2 16.05940747 15.18009493 15.2130083 14.35559802 13.48523962 14.54253699 7.591756379 8.090473313 8.629122351 17.49042393 17.74007536 18.27080601 17.37764772 17.27871675 17.3862861 7.159547385 7.874981651 6.95183983 Exchange Rate [%]: 3 0.938621029 0.960877676 0.930544088 1.042244263 1.042294595 1.030787476 0.898413387 0.782717906 0.996887819 1.152173074 1.226971336 1.250011039 1.278066123 1.313729917 1.189754909 0.700541913 0.735656775 0.800821315 Exchange Rate [%]: 4 0.302894261 0.321907249 0.352728295 0.364631603 0.3330168 0.334729614 0.182813473 0.175007107 0.12903129 0.358857182 0.4668099 0.44058933 0.531887007 0.417986101 0.50017033 0.163365778 0.108298195 0.107928212 Exchange Rate [%]: 5 0.091576369 0 0 0.099736128 0.072628536 0 0 0 0 0.056277851 0.103497425 0.074902823 0.107795218 0.133150645 0.131041155 0.033441797 0.011863008 0.017584906 Malate 488208357.9 619545795.4 613694818.8 757640632.1 669140088.7 728739832.5 808803859.4 698738214.1 916993087.1 460724832.1 405812948.1 420656930.4 594185452.2 634960708.1 573157374.1 702789057.5 524601238.6 654114442.3 Exchange Rate [%]: 0 94.15233315 92.34217246 94.0275608 92.8658906 93.14557268 93.16022651 94.26315546 92.44050876 92.34345494 92.62697856 92.97006535 93.48437973 92.04129142 91.86222698 92.39737214 93.31036623 92.13569728 93.10289696 Exchange Rate [%]: 1 2.387221881 3.910333689 2.094537052 2.863949808 2.995164082 2.835379716 1.780413995 3.377215727 3.393168742 2.848596172 2.391104781 2.385272539 3.411684439 3.415753319 2.901392674 3.162147588 3.909539965 3.209436419 Exchange Rate [%]: 2 2.029808475 2.254191287 2.831095321 2.602263232 2.6701822 2.582433937 2.113702829 2.615234464 2.765113391 2.971059025 2.70602964 2.645929317 3.072194996 3.199529621 2.910810804 2.238138432 2.564207955 2.342303855 Exchange Rate [%]: 3 1.351098422 1.446172499 0.994970544 1.562152036 1.111769508 1.367384044 1.787436476 1.474813374 1.431251994 1.44765295 1.836048858 1.406353555 1.394598128 1.398261526 1.68498677 1.239948566 1.31661672 1.258661093 Exchange Rate [%]: 4 0.079538075 0.047130063 0.051836283 0.105744327 0.077311531 0.054575789 0.055291246 0.092227672 0.067010928 0.105713291 0.096751366 0.078064855 0.080231016 0.12422855 0.105437609 0.049399179 0.073938081 0.086701671 Fumarate 39589783.19 41033962.28 40108700.26 43151287.13 46093816.01 41562757.76 45581202.38 62641054.51 70245024.74 21509158.57 23480185.31 27547512.45 28324468.12 23297168.8 30404917.82 30400505.85 35229826.84 28595192.98 Exchange Rate [%]: 0 94.32805942 93.47013456 94.33629388 92.97408426 92.81822525 93.09586052 92.5035134 92.27487101 92.24897733 93.82448786 93.86735955 93.37773323 92.28132322 92.36713428 91.99769404 92.77840949 92.80374266 92.92705531 Exchange Rate [%]: 1 1.95740074 2.51643624 2.146991622 2.82257866 3.058765775 2.627365419 3.229918901 3.60136853 3.348770454 2.073693297 2.268296748 2.359429101 3.063664162 3.053287645 3.295443171 3.307194928 3.390179324 3.358811653 Exchange Rate [%]: 2 2.270106501 2.541923451 2.276471035 2.741635356 2.813371397 2.790386752 2.810322314 2.568356205 2.869083367 2.676120214 2.570714191 2.744983678 3.209246957 3.139034168 3.265161227 2.662203094 2.545604288 2.484593695 Exchange Rate [%]: 3 1.444433341 1.471505751 1.240243463 1.461701725 1.309637576 1.48638731 1.456245384 1.555404251 1.533168849 1.42569863 1.293629515 1.517853992 1.445765663 1.440543906 1.441701561 1.252192491 1.260473731 1.229539338 Exchange Rate [%]: 4 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 2-Hydroxyisocaproic acid 19604602.14 20969059.76 19394948.57 47747074.02 48241808.43 46219698.48 280460536 262963150.7 254800095.7 16729677.22 15367386.4 17037355.4 37647872.43 38913528.77 39199508.03 182531819.6 185417501.1 201300284.8 Exchange Rate [%]: 0 66.2976562 59.53750822 55.97606745 28.54229368 23.23576561 25.73093474 19.26261339 19.43752834 18.97907131 61.60870348 64.01821676 61.1353861 27.90153934 25.84573666 25.67661948 16.2461153 15.32623779 14.3776784 Exchange Rate [%]: 1 0 0 0 0 0 0 0.778746096 0.090780681 0.08062901 0 0 0 0 0 0 0.036856747 0 0.022405481 Exchange Rate [%]: 2 0.749180456 1.128502536 1.555736283 4.862022645 6.905406493 7.048735268 12.70492983 12.81380286 12.83003079 0.281487242 0.224687559 0.49340159 5.467036227 5.332828646 5.37742539 9.003724482 8.700843541 6.767015745 Exchange Rate [%]: 3 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 0 Exchange Rate [%]: 4 0 0 0 1.1575E-06 1.33667E-06 2.06447E-06 2.51977E-06 2.26843E-06 2.56032E-06 0 0 0 1.87526E-06 1.90564E-06 1.70608E-06 2.24548E-06 2.55859E-06 2.28009E-06 Exchange Rate [%]: 5 1.48737E-05 1.77538E-05 0.498444637 2.066055101 2.306464098 3.103910962 3.198005231 2.930790887 3.250526263 0.22471615 1.61393E-05 1.73192E-05 2.882228144 2.941430781 2.716027397 3.166255997 3.407378547 3.356203653 Exchange Rate [%]: 6 32.95314847 39.33397149 41.96975163 64.52962742 67.55236246 64.11641696 64.05570293 64.72709496 64.85974007 37.88509313 35.75707954 38.37119499 63.74919442 65.88000201 66.22992603 71.54704523 72.56553756 75.47669444