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MB Sample ID: SA245081
Local Sample ID: | 47_4_15 |
Subject ID: | SU002540 |
Subject Type: | Mammal |
Subject Species: | Mus musculus |
Taxonomy ID: | 10090 |
Genotype Strain: | APOE-targeted replacement mice homozygous for human E3 (B6.129P2-Apoe^tm2(APOE*3)Mae N8, Taconic #1548-F) or human E4 (B6.129P2- Apoe^tm3(APOE*4)Mae N8, Taconic #1549-F) alleles |
Age Or Age Range: | P0-P3 |
Gender: | Pooled |
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Treatment:
Treatment ID: | TR002552 |
Treatment Summary: | APOE3/3 and APOE4/4 primary microglia were treated for 2 hours with a pro-inflammatory cocktail of 20ng/ml interferon-γ (IFNγ, R&D Systems #485-MI-100) and 50ng/ml tumor necrosis factor α (TNFα, R&D Systems #410-MT-025) or vehicle control. |