metabolite_name WT_1 WT_2 WT_3 WT_4 WT_5 WT_6 Crp_1 Crp_2 Crp_3 Crp_4 Crp_5 Crp_6 Evocrp1_1 Evocrp1_2 Evocrp1_3 Evocrp1_4 Evocrp1_5 Evocrp1_6 Evocrp2_1 Evocrp2_2 Evocrp2_3 Evocrp2_4 Evocrp2_5 Evocrp2_6 Evocrp3_1 Evocrp3_2 Evocrp3_3 Evocrp3_4 Evocrp3_5 Evocrp3_6 Evocrp4_1 Evocrp4_2 Evocrp4_3 Evocrp4_4 Evocrp4_5 Evocrp4_6 Evocrp5_1 Evocrp5_2 Evocrp5_3 Evocrp5_4 Evocrp5_5 Evocrp5_6 Leucine 0.753040153 0.965358933 1.2744693 1.382546346 0.904619928 0.922430037 2.030149845 1.745384285 1.453685764 2.027128292 2.48866209 2.086263148 2.211152814 2.047506994 2.116961658 2.059997118 1.721185159 1.878934776 2.594171087 2.522841393 1.580803861 1.553090632 2.592595527 1.748608852 1.359006361 1.428705782 1.450897575 1.476530119 1.537025194 1.51095517 1.873329902 1.811224986 2.100620975 1.687056592 1.853860253 1.683952867 2.637372139 2.453493525 2.233588135 2.375600779 2.439875412 2.516546065 Phenylalanine 0.407826029 0.496322994 0.625638283 0.562497396 0.340150371 0.347085312 0.662585798 0.598568766 0.587966631 0.671315831 0.77629815 0.654645683 0.629096881 0.648638269 0.636624277 0.632923363 0.577442762 0.622536149 0.710605573 0.754014961 0.502735658 0.496409289 0.758676633 0.553653034 0.507553866 0.548962563 0.553733228 0.547537792 0.605756254 0.562540748 0.627502701 0.595112582 0.810960149 0.671849658 0.582498143 0.658484995 0.799471115 0.965866904 0.780808764 0.799652258 0.922302662 0.958830638 Isoleucine 0.306458323 0.383794776 0.278182991 0.431539332 0.310786559 0.325690628 0.361572835 0.311966841 0.382283423 0.341883675 0.409302167 0.428951142 0.37344487 0.561136072 0.367442156 0.363839748 0.533441475 0.508335721 0.435014011 0.533652464 0.422385495 0.439828763 0.351171292 0.476747566 0.353770694 0.404078303 0.446512109 0.388654832 0.440833839 0.449780109 0.346076662 0.366296835 0.335972701 0.428482479 0.369768867 0.441310561 0.229461852 0.24372788 0.35398728 0.319172544 0.278991006 0.430232031 Methionine 0.634267572 0.837133702 0.990772047 1.386227819 0.863318528 0.909002342 1.015537167 0.974046501 0.806381228 0.637872467 0.731999802 1.093534835 1.079854896 1.333098753 1.031427133 1.016344972 1.025454042 1.188978356 1.417857502 1.446725052 0.987637611 0.963480657 1.474614082 1.100752244 0.93809627 1.040002511 1.074892659 1.042880619 1.095908192 1.051017693 1.683295006 1.687767182 2.055192907 1.728129883 1.649412971 1.710141892 2.46621218 2.412090307 1.933426574 2.492206703 2.688068745 2.513947859 Tryptophan 0.444134954 0.543101257 0.526005761 0.664933136 0.432482634 0.440435932 0.620552169 0.541125917 0.58963203 0.463603017 0.416323916 0.65854435 0.67081988 0.737097048 0.652044649 0.64116513 0.737245059 0.703328577 0.560678591 0.564577636 0.597951881 0.584750101 0.597941686 0.68551502 0.63105617 0.64899846 0.699704574 0.685028176 0.72310094 0.673191601 0.562133177 0.545093272 0.424529768 0.598336765 0.560551692 0.588392792 0.385799287 0.380583924 0.472617156 0.413762696 0.391695918 0.338949465 Proline 0.744190616 0.963356551 1.28974574 1.159193513 0.770338041 0.820289368 1.353833822 0.988149515 0.830589186 1.203329943 1.724226461 1.417276245 1.681516128 1.555762626 1.706168217 1.765076819 1.240837826 1.391451112 2.396212835 2.402000092 1.160655059 1.168353241 2.453969379 1.259254343 0.956093467 1.01794125 1.018255261 1.022311432 1.106546199 1.050103845 1.555442042 1.497168484 2.132633137 1.37063797 1.537359138 1.391245233 3.683148892 3.737990617 2.597080659 3.596156623 3.770715822 3.799191096 Valine 1.082072156 1.388245741 1.843039685 1.683405832 1.11387601 1.054986705 0.928279311 0.790923761 0.842326866 0.854816225 0.981573983 0.915703995 0.439847315 0.419126793 0.364138034 0.427597586 0.3858529 0.431404039 0.529601297 0.497644892 0.360976313 0.318475761 0.51257175 0.386487902 0.298697672 0.295016236 0.31973248 0.326457396 0.326348855 0.306281697 0.291777267 0.327374323 0.336453084 0.313707934 0.334012638 0.283011366 0.544598395 0.388704695 0.388608408 0.519760584 0.36044676 0.475126788 Tyrosine 0.277811686 0.339190618 0.364703722 0.435648717 0.28638655 0.29203444 0.257172573 0.247210208 0.224395361 0.253840366 0.229185016 0.238094007 0.311517485 0.320698998 0.299629901 0.290329082 0.289403877 0.292954104 0.352764579 0.364658069 0.264039221 0.276848274 0.359601648 0.296423249 0.264510264 0.29215648 0.298723423 0.285383632 0.322562672 0.293923916 0.286632457 0.329661589 0.386078476 0.35327869 0.334287095 0.344960599 0.435490465 0.455199203 0.409179105 0.427635627 0.468598776 0.447233342 Alanine 0.484027465 0.881073801 1.232067287 1.601952929 0.996265216 0.909162158 1.655625284 1.406886141 0.999272479 1.135253284 1.42348994 1.67495034 1.176400417 1.386120072 1.058643975 1.011964584 0.949573352 1.364770006 1.655942445 1.732690639 1.073452171 1.120988471 1.670258655 1.217792505 1.015243355 1.087166832 1.114942021 1.128534319 1.219788696 1.151151596 1.531873247 1.595316741 1.935149589 1.724011492 1.602417109 1.716861415 1.970584041 2.14627215 2.37090854 2.049548601 1.862903739 2.160418639 Threonine 0.309813241 0.396012918 0.538997986 0.506747802 0.292232441 0.307158468 0.592745972 0.49740089 0.427322216 0.405930277 0.474804697 0.646616223 0.570482251 0.508571514 0.564254916 0.449524926 0.454270225 0.418529522 0.693257313 0.693199429 0.400607618 0.425521191 0.675780848 0.474398009 0.419868462 0.434355294 0.457939674 0.443783284 0.49825367 0.448716822 0.453008372 0.479185814 0.306887599 0.339350544 0.485256529 0.348763517 0.413095383 0.317176263 0.517254998 0.377225958 0.323463843 0.333268881 Glutamine 0.214621236 0.192672302 0.363362303 0.07761426 0.052326756 0.050530653 0.473425884 0.245857305 0.202235179 0.144561824 0.353468573 0.50064034 0.383291421 0.114758115 0.372313373 0.29403713 0.122765121 0.094066224 0.533396285 0.533799488 0.088324566 0.08938931 0.524157619 0.09732566 0.084848138 0.098981793 0.089518234 0.091142238 0.106120334 0.091226694 0.070005288 0.070827251 0.111115359 0.046198907 0.068402157 0.048099655 0.438811938 0.344556836 0.137790816 0.493003229 0.284930304 0.337461855 Glycine 0.320828571 0.526437575 0.525078729 0.743777149 0.66141718 0.654225131 0.953977606 0.889002407 0.89876979 0.962759202 0.865830645 1.035653723 12.27965563 0.984106975 11.07862006 0.697177521 0.938720202 0.916522187 1.013529781 1.0028177 9.242066532 8.83198594 0.980457687 10.4520131 1.633760707 1.884162028 1.724686138 1.750755415 2.046035411 1.734202191 0.785233682 0.670486382 0.896490377 0.906623499 0.77243945 0.821149844 1.020519307 0.917042555 1.569866434 0.695048287 1.413306373 0.962587153 Aspartate 0.222158878 0.303864448 0.244547717 0.337640474 0.277791815 0.273862046 0.857791184 0.984722255 0.759788654 0.390240443 0.394847414 0.911251208 0.318743487 0.447994285 0.302009989 0.273788532 0.431380165 0.402216754 0.462102398 0.476521057 0.289507242 0.300205043 0.462217844 0.315448765 0.214596384 0.312723978 0.330725625 0.242510944 0.357141824 0.325784818 0.496946786 0.560263109 0.839806536 0.73642695 0.570573804 0.725624147 0.892460158 0.988797645 0.604036999 0.860953673 1.060884951 0.999525697 Asparagine 0.242933166 0.247679557 0.255020689 0.159152774 0.11707649 0.118756126 0.182267129 0.150313109 0.080184273 0.095179322 0.145174779 0.18962875 0.356024297 0.190970546 0.31246419 0.291656986 0.214397433 0.153181988 0.334137715 0.340997597 0.154264236 0.16020265 0.334261415 0.170543328 0.175650428 0.170280556 0.16453763 0.183542498 0.195551163 0.165534875 0.102029431 0.091635267 0.24024898 0.073790398 0.095087681 0.073726289 0.35209162 0.43162601 0.191396958 0.336434307 0.402171843 0.494735628 Serine 1.735123919 1.595280779 1.300756567 2.029647358 1.355152514 1.384734318 2.199381812 2.110155183 2.102742141 2.646482917 1.954715344 2.50987817 1.978289885 3.124690839 2.191209993 1.886741079 2.138994465 2.300740156 3.044942857 2.937836033 2.732660958 2.826848064 3.064354588 2.98721782 1.708834595 2.107862916 2.127976748 2.022088918 2.173605138 2.191161594 4.05589151 3.524868915 1.747188476 3.257952059 3.406709813 3.308675299 1.735137526 2.057276935 15.22017213 2.234448892 3.648454622 1.352531967 Glutamate 0.246087006 0.328901792 0.425818988 0.391704408 0.261603499 0.2634754 1.165142082 0.848489322 0.592146413 0.709683556 1.271788522 1.223410851 0.746921514 0.600599496 0.72471902 0.567727757 0.477469722 0.448956051 1.046314831 1.084524095 0.51865863 0.516484902 1.066864343 0.572419732 0.451451976 0.486627492 0.49523248 0.480041703 0.530766775 0.485094702 0.572672636 0.591461685 0.721486961 0.553804061 0.5975525 0.555601144 1.153806924 0.900847477 0.881455173 0.800205142 0.80916021 1.2231338 Lysine 0.117533724 0.148809534 0.179514531 0.196858983 0.117725673 0.109224491 0.226032725 0.217837115 0.173365249 0.206732393 0.220232351 0.225233522 0.194289855 0.185590511 0.180830281 0.194525736 0.175223052 0.173399211 0.208062362 0.220428582 0.148947249 0.146033644 0.209760569 0.162552282 0.16376349 0.174622577 0.191256006 0.17935665 0.183061264 0.190206755 0.163766393 0.170069328 0.184290608 0.159708233 0.17002321 0.166093915 0.253994065 0.257118523 0.188517869 0.250810515 0.261544805 0.271064839 Arginine 0.323948224 0.411528153 0.461001625 0.524759426 0.336855751 0.335480738 0.458298476 0.416993769 0.328652762 0.348029654 0.387039177 0.49331181 0.438348514 0.415146454 0.412114125 0.426280822 0.349608577 0.387333355 0.512507375 0.508749436 0.328175047 0.326669583 0.503092797 0.361433433 0.31795469 0.339482236 0.411220509 0.36478278 0.383249799 0.40208306 0.393441166 0.406800597 0.385763821 0.369563282 0.407582749 0.374419393 0.580503845 0.539631873 0.441240953 0.574249764 0.546584461 0.546298141 Histidine 0.234754366 0.278211113 0.309774983 0.34301948 0.212001178 0.211748095 0.309710991 0.289393271 0.288480978 0.277049935 0.301307874 0.340204104 0.335982731 0.322481895 0.293377837 0.299069522 0.313118949 0.303195106 0.343863352 0.351466433 0.282993418 0.280587442 0.3458421 0.313749756 0.280420123 0.317493606 0.324681922 0.31074043 0.362651548 0.336346791 0.326269651 0.325872915 0.279021412 0.319274271 0.30957184 0.325354044 1.393393605 0.305630624 0.617510902 1.372903579 0.342877704 0.28156271 NAD 0.279674933 0.348463301 0.359469004 0.412113573 0.274456662 0.280397558 0.409241922 0.394375869 0.357657023 0.357686452 0.350393461 0.431870892 0.396617563 0.397255072 0.387117681 0.387515341 0.365356755 0.360721079 0.395602575 0.384957626 0.315869959 0.3159488 0.391293885 0.349390413 0.324505309 0.357354561 0.37363465 0.355636749 0.381332425 0.377224087 0.339504803 0.331981296 0.319753485 0.32353737 0.335046995 0.321506019 0.412334935 0.404897234 0.33532928 0.408342188 0.42257718 0.421861086 NADPH 0.270013058 0.349395273 0.378461871 0.419348476 0.294903012 0.296131166 0.352925033 0.350196598 0.318925413 0.346587738 0.341559348 0.386152781 0.306997343 0.358889987 0.292273968 0.342043366 0.35274592 0.297614542 0.322133173 0.348855076 0.265321302 0.277277204 0.350463302 0.267334121 0.26142888 0.281693761 0.319971091 0.280823702 0.250818041 0.313004447 0.26861083 0.304232595 0.362211053 0.281199043 0.281802983 0.121140818 0.39120173 0.346848117 0.029194331 0.318481095 0.315053875 0.308742141 metabolite_name quantitated m/z KEGG_id Leucine 132.1019 C00123 Phenylalanine 166.0862 C00079 Isoleucine 132.1019 C00407 Methionine 150.0583 C00073 Tryptophan 205.0971 C00078 Proline 116.0706 C00148 Valine 118.0862 C00183 Tyrosine 182.0811 C00082 Alanine 90.0549 C00041 Threonine 120.0655 C00188 Glutamine 147.0764 C00064 Glycine 76.0393 C00037 Aspartate 134.0447 C00049 Asparagine 133.0607 C00152 Serine 106.0498 C00065 Glutamate 148.0604 C00025 Lysine 147.1128 C00047 Arginine 175.1189 C00062 Histidine 156.0767 C00135 NAD 664.1163 C00003 NADPH 746.0983 C00005