metabolite_name WT_1 WT_2 WT_3 WT_4 WT_5 WT_6 Crp_1 Crp_2 Crp_3 Crp_4 Crp_5 Crp_6 Evocrp1_1 Evocrp1_2 Evocrp1_3 Evocrp1_4 Evocrp1_5 Evocrp1_6 Evocrp2_1 Evocrp2_2 Evocrp2_3 Evocrp2_4 Evocrp2_5 Evocrp2_6 Evocrp3_1 Evocrp3_2 Evocrp3_3 Evocrp3_4 Evocrp3_5 Evocrp3_6 Evocrp4_1 Evocrp4_2 Evocrp4_3 Evocrp4_4 Evocrp4_5 Evocrp4_6 Evocrp5_1 Evocrp5_2 Evocrp5_3 Evocrp5_4 Evocrp5_5 Evocrp5_6 Pyruvate 0.447773684 0.850593835 1.326699998 1.385633734 0.827467543 0.821426881 0.976731638 1.451029271 0.562611482 1.133671945 1.155651818 1.043734825 1.004322492 1.199737741 0.955733348 0.936693809 1.263411334 1.098995866 1.343130545 1.292550368 1.313116205 1.451367304 1.301314823 1.414939069 0.774173798 0.99077536 0.935394562 0.845917804 1.073072852 0.953458492 1.602095484 1.734411297 1.342718146 2.499445918 1.817711042 2.64955641 1.052201381 1.144611772 1.904481689 0.989673754 1.834327073 1.101146812 alpha-Ketoglutarate 0.218478817 0.162521794 0.32587621 0.422649308 0.296941225 0.338216828 0.546881946 0.51070279 0.259763928 0.43120915 0.533682061 0.642407547 1.087819196 1.512066582 1.053663251 1.210772866 0.85705509 1.51479383 0.775721255 0.648646977 0.75420992 0.750050346 0.956624885 0.868303181 0.516674075 0.642775994 0.693127957 0.481752397 0.829170989 0.72977449 1.104124903 1.119845132 0.815635602 0.783791378 1.17805466 0.710792118 0.684200226 0.606945866 0.919787088 0.633393118 0.643017218 0.596025111 Ribose-5-Phosphate 1.03467623 2.284182232 2.659898226 2.372523161 1.545505041 2.853867056 7.425856696 4.516578368 8.902856921 3.734180286 4.054842124 7.891285084 4.65396642 10.79188911 7.168730203 3.362647599 8.464957636 5.817821659 2.338955657 2.599625431 3.292534168 1.960498804 3.798991749 2.570975202 7.107967205 9.914892551 9.342352176 7.731949952 20.86128689 15.41955598 1.517705529 1.398242044 0.904132912 3.157418571 4.059304579 4.211980742 5.673762532 2.038286083 2.327935527 1.990009425 0.801343994 3.305087089 Fructose-6-Phosphate 0.977499078 1.486339703 1.716107966 1.116220055 0.718791994 1.267000285 1.400849201 1.104534718 0.981579537 2.123973476 2.120235652 1.34317355 1.005043032 0.956339544 0.808288858 0.954706158 0.945204378 0.942637998 1.196451602 1.205797436 1.055264562 0.961390874 1.134387607 1.184413926 0.700907355 0.853657205 0.887074422 0.803140507 1.025249863 0.953955331 1.016171059 0.991731335 1.318117209 1.658094269 1.204515 1.608943576 1.042131207 1.095608435 4.241116277 1.02252011 0.764696874 1.238914128 Malate 2.330035728 1.699614667 0.935246112 5.872744068 3.129760903 3.549697101 6.963076415 6.879415336 4.109743654 5.0781514 5.481395528 7.410092985 4.305151083 6.659716194 4.299060398 4.279879451 4.693590485 6.079919495 5.939769817 5.970928174 5.500869581 5.743048253 5.832115428 6.302890846 4.431206088 4.817908607 5.472919412 4.711840753 5.418228943 5.91806645 5.677957094 5.64117237 3.781267555 5.272725506 5.666195225 5.34763145 4.597171516 3.43095121 6.30260645 4.56879093 3.519179283 3.155092837 Glucose-6-Phosphate 0.873774058 1.015109382 1.066616783 0.580389387 0.786387959 0.78673105 1.210020383 1.037458469 1.191703203 1.871207023 1.878343341 1.203875886 1.004322492 1.199737741 0.955733348 0.936693809 1.263411334 1.098995866 1.343130545 1.292550368 1.313116205 1.451367304 1.301314823 1.414939069 0.774173798 0.99077536 0.935394562 0.845917804 1.073072852 0.953458492 1.602095484 1.734411297 1.342718146 2.499445918 1.817711042 2.64955641 1.052201381 1.144611772 1.904481689 0.989673754 1.834327073 1.101146812 Phosphoenolpyruvate 0.0521336 0.046371187 0.049905043 0.804264815 0.29044104 0.286117197 2.425611426 2.079677968 2.327979178 1.780797871 2.030401219 2.558297406 0.204523708 0.552898882 0.196194858 0.196943875 0.190100814 0.498548639 0.447344893 0.440625967 0.444206278 0.451057871 0.446041113 0.501984644 0.277964266 0.327745425 0.426806919 0.304359182 0.377988321 0.42444459 1.101395622 1.178146771 4.082845145 1.556672727 1.13600538 1.563693805 3.201197568 3.288985914 3.048690225 3.094335526 3.345160163 3.318550589 Citrate 0.384205834 0.453096721 0.361451585 0.285740268 0.194593192 0.196611568 0.133118768 0.17176495 0.272847809 0.209316984 0.136419932 0.141860358 0.289913472 0.365425127 0.400238807 0.279241125 0.426415892 0.327375104 0.293790842 0.303197656 0.372237799 0.395355266 0.294886278 0.427710837 0.244394119 0.340081972 0.387448549 0.266623819 0.381541949 0.386780072 0.501576266 0.238563204 0.189045656 0.25793825 0.247583981 0.258031881 0.169855745 0.179654994 0.342362925 0.164494294 0.271581975 0.16802996 cAMP 0.04244999 0.040012814 0.063508414 0.047200206 0.030981528 0.031458716 2.216893973 2.116119892 2.040058726 3.295081282 2.073619474 2.330141838 0.428509045 0.290317864 0.409260496 0.427480868 0.359967302 0.239136697 0.188650122 0.188711478 0.086414423 0.100349877 0.182983909 0.099028222 0.20427676 0.290325678 0.353516867 0.213803118 0.346361175 0.385992383 0.321915497 0.306215806 0.874977549 0.50005776 0.348311513 0.470691201 0.872626683 1.124184732 0.51013156 0.84098451 1.071831188 1.30334019 Fructose-1,6-bisphosphate 1.654356108 2.620107083 3.206150559 3.138104929 2.359480041 2.267646145 1.709871538 1.394703924 1.228390204 2.044841216 1.892697176 1.807212999 2.253869044 2.814591134 2.031006508 2.833239121 2.268002874 2.734734668 2.627656269 3.04661111 2.761776786 0.762543988 2.994968406 2.982073565 2.197729506 2.4139482 2.388039794 2.428774695 2.697704789 2.473933834 2.902110222 0.295029545 0.71187536 2.646921459 2.486047743 2.870511006 2.015713774 0.578430189 13.18240933 1.966464603 2.364435559 1.295250288 Glycerate-3-phosphate 0.310160877 0.519340632 0.403799844 1.287861925 0.997098215 0.988821626 2.062809862 2.711624483 2.271800365 2.223505354 2.02413319 2.212150745 0.860488169 1.738385537 0.728564913 0.855002385 1.174337472 1.565851858 1.094059255 1.1049358 1.245677964 1.202691275 1.095240596 1.345383112 0.916865619 1.252898682 1.305387694 0.983368293 1.321233603 1.347271542 1.434550926 1.885656347 2.766661644 2.886624992 1.846194527 2.834474309 2.292718754 2.046380773 1.638610105 2.261677376 2.497397705 2.576696737 AMP 0.353160056 1.066339473 0.578303759 1.148710276 1.254249755 1.24010486 1.837217342 1.296377648 1.901525665 0.901194892 0.767853942 1.82669062 1.514150386 1.747213346 1.232459931 1.201496459 1.703418268 1.630246685 1.108877199 1.101006205 1.124817017 1.123165152 1.13116479 1.265044731 1.721967329 1.786236795 1.861070257 1.946236941 1.911011 2.026603708 1.038935915 1.118645253 0.631184779 1.475003227 1.083888068 1.546809428 0.714489006 0.564927415 0.456661441 0.711977245 0.472959614 0.643517184 ADP 0.485072874 0.626806245 0.606137669 0.607859615 0.332702285 0.335892466 0.588343709 0.612531894 0.526707943 0.605977168 0.514630836 0.613006869 0.650253784 0.637379366 0.615397587 0.662390586 0.664037107 0.605567948 0.59824267 0.594897125 0.523228527 0.553751215 0.596307262 0.62143502 0.446702108 0.544665125 0.583294193 0.50535064 0.581843412 0.575394114 0.453102133 0.511816314 0.398071873 0.467094441 0.553957767 0.494805773 0.596548412 0.583440637 0.426930694 0.57538649 0.464986623 0.549971847 ATP 0.904008093 0.518912837 0.819518756 0.555369623 0.151459988 0.150410687 0.305230969 0.512618817 0.264916119 0.724573407 0.753059231 0.326088569 0.473174608 0.363880953 0.502646946 0.468598468 0.384145352 0.363421535 0.597744585 0.60383827 0.523241635 0.34890646 0.571578298 0.549735264 0.230042618 0.313844867 0.299951969 0.262296165 0.295167807 0.334461024 0.409484289 0.362894124 0.725793078 0.294466217 0.385122964 0.328027065 0.78078455 0.783786546 0.803671283 0.755340615 0.840160788 0.833234235 metabolite_name quantitated m/z KEGG_id Pyruvate 87.0087 C00022 alpha-Ketoglutarate 145.0142 C00026 Ribose-5-Phosphate 229.0118 C00117 Fructose-6-Phosphate 259.0224 C00085 Malate 133.0142 C00149 Glucose-6-Phosphate 259.0224 C00092 Phosphoenolpyruvate 166.975 C00074 Citrate 191.0191 C00158 cAMP 328.0452 C00575 Fructose-1,6-bisphosphate 338.9887 C00354 Glycerate-3-phosphate 184.9856 C00190 AMP 346.0558 C00020 ADP 426.0221 C00008 ATP 505.9885 C00002