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MB Sample ID: SA005402

Local Sample ID:T30-2
Subject ID:SU000114
Subject Type:Animal
Subject Species:Mus musculus
Taxonomy ID:10090
Age Or Age Range:9 months
Animal Housing:Singly housed
Animal Feed:High fat diet (HFD, 4.73 kcal/g, 20% protein, 35% carbohydrate, and 45% fat per kcal; D12451, Research Diets, New Brunswick, NJ)
Species Group:Mammal

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Treatment ID:TR000115
Treatment Summary:1.7 mg DDT/kg body weight was administered to dams daily on gestational day 11 through postnatal day 5 and litters were culled to 6 mice at postnatal day 6. Mice were metabolically screened from 2-6 months when they consumed a high fat diet. Mice were sacrificed at 9 months of age.
Treatment Protocol Filename:Newman_Lab_Bile_Acid_Protocols_La_Merrill_WCMC_P&F.pdf
Treatment Compound:p,p`-DDT, o,p`-DDT
Treatment Route:Oral
Treatment Dose:77.2% p,p`-DDT (98.5% purity neat, AccuStandard, New Haven, CT) and 22.8% o,p`-DDT (100% purity neat, AccuStandard) were dissolved at a final concentration of 0.17 g DDT mixture/L organic olive oil
Treatment Doseduration:From 11.5 days post coitus to postnatal day 5
Treatment Vehicle:Olive oil
Animal Endp Euthanasia:9 months
Animal Endp Tissue Coll List:Liver
Animal Endp Tissue Proc Method:Dissected, placed on dry ice