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MB Sample ID: SA005403
| Local Sample ID: | T18-3 |
| Subject ID: | SU000114 |
| Subject Type: | Animal |
| Subject Species: | Mus musculus |
| Taxonomy ID: | 10090 |
| Age Or Age Range: | 9 months |
| Gender: | Female |
| Animal Housing: | Singly housed |
| Animal Feed: | High fat diet (HFD, 4.73 kcal/g, 20% protein, 35% carbohydrate, and 45% fat per kcal; D12451, Research Diets, New Brunswick, NJ) |
| Species Group: | Mammals |
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Treatment:
| Treatment ID: | TR000115 |
| Treatment Summary: | 1.7 mg DDT/kg body weight was administered to dams daily on gestational day 11 through postnatal day 5 and litters were culled to 6 mice at postnatal day 6. Mice were metabolically screened from 2-6 months when they consumed a high fat diet. Mice were sacrificed at 9 months of age. |
| Treatment Protocol Filename: | Newman_Lab_Bile_Acid_Protocols_La_Merrill_WCMC_P&F.pdf |
| Treatment: | Intervention |
| Treatment Compound: | p,p`-DDT, o,p`-DDT |
| Treatment Route: | Oral |
| Treatment Dose: | 77.2% p,p`-DDT (98.5% purity neat, AccuStandard, New Haven, CT) and 22.8% o,p`-DDT (100% purity neat, AccuStandard) were dissolved at a final concentration of 0.17 g DDT mixture/L organic olive oil |
| Treatment Doseduration: | From 11.5 days post coitus to postnatal day 5 |
| Treatment Vehicle: | Olive oil |
| Animal Endp Euthanasia: | 9 months |
| Animal Endp Tissue Coll List: | Liver |
| Animal Endp Tissue Proc Method: | Dissected, placed on dry ice |
