Summary of Study ST002155
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001368. The data can be accessed directly via it's Project DOI: 10.21228/M8WH7S This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST002155 |
| Study Title | Longitudinal metabolomic stool dynamics in primary C. difficile infections |
| Study Summary | Subjects with primary C. difficile infections followed for up to 2 months after diagnosis with stool metabolomics |
| Institute | Brigham and Women's Hospital |
| Last Name | Bry |
| First Name | Lynn |
| Address | 221 Longwood Ave, Boston, MA, 02115, USA |
| lbry@bwh.harvard.edu | |
| Phone | (617) 732-5500 |
| Submit Date | 2021-12-20 |
| Analysis Type Detail | LC-MS |
| Release Date | 2022-05-13 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
| Project ID: | PR001368 |
| Project DOI: | doi: 10.21228/M8WH7S |
| Project Title: | Longitudinal stool metabolomics in primary CDI |
| Project Summary: | Longitudinal study of primary, uncomplicated C. difficile infection. |
| Institute: | Brigham Women's Hospital |
| Department: | Internal Medicine, Gastroenterology; Pathology |
| Laboratory: | Allegretti, Bry |
| Last Name: | Bry |
| First Name: | Lynn |
| Address: | 221 Longwood Ave, Boston, MA, 02115, USA |
| Email: | lbry@bwh.harvard.edu |
| Phone: | (617) 732-5500 |
| Funding Source: | BWH Precision Medicine Institute |
Subject:
| Subject ID: | SU002241 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Human Trial Type: | Longitudinal |
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Week |
|---|---|---|
| SA206625 | 124-0 | - |
| SA206626 | 130-0 | - |
| SA206627 | 132-0 | - |
| SA206628 | 109-0 | - |
| SA206629 | 144-0 | - |
| SA206630 | 126-0 | - |
| SA206631 | 133-0 | - |
| SA206632 | 127-0 | - |
| SA206633 | 168-0 | - |
| SA206634 | 138-0 | - |
| SA206635 | 163-0 | - |
| SA206636 | 139-0 | - |
| SA206637 | 143-0 | - |
| SA206638 | 134-0 | - |
| SA206639 | 102-0 | - |
| SA206640 | 114-0 | - |
| SA206641 | 115-0 | - |
| SA206642 | 145-0 | - |
| SA206643 | 151-0 | - |
| SA206644 | 169-0 | - |
| SA206645 | 108-0 | - |
| SA206646 | 170-0 | - |
| SA206647 | 120-0 | - |
| SA206648 | 146-0 | - |
| SA206649 | 175-0 | - |
| SA206650 | 155-0 | - |
| SA206651 | 139-1 | 1 |
| SA206652 | 132-1 | 1 |
| SA206653 | 161-1 | 1 |
| SA206654 | 168-1 | 1 |
| SA206655 | 129-1 | 1 |
| SA206656 | 143-1 | 1 |
| SA206657 | 106-1 | 1 |
| SA206658 | 146-1 | 1 |
| SA206659 | 121-1 | 1 |
| SA206660 | 103-1 | 1 |
| SA206661 | 149-1 | 1 |
| SA206662 | 127-1 | 1 |
| SA206663 | 174-1 | 1 |
| SA206664 | 158-1 | 1 |
| SA206665 | 114-1 | 1 |
| SA206666 | 148-1 | 1 |
| SA206667 | 136-1 | 1 |
| SA206668 | 124-1 | 1 |
| SA206669 | 105-1 | 1 |
| SA206670 | 162-1 | 1 |
| SA206671 | 165-1 | 1 |
| SA206672 | 120-1 | 1 |
| SA206673 | 119-1 | 1 |
| SA206674 | 108-1 | 1 |
| SA206675 | 167-1 | 1 |
| SA206676 | 151-1 | 1 |
| SA206677 | 147-1 | 1 |
| SA206678 | 160-1 | 1 |
| SA206679 | 155-1 | 1 |
| SA206680 | 145-1 | 1 |
| SA206681 | 115-1 | 1 |
| SA206682 | 134-1 | 1 |
| SA206683 | 175-1 | 1 |
| SA206684 | 144-1 | 1 |
| SA206685 | 130-1 | 1 |
| SA206686 | 123-1 | 1 |
| SA206687 | 140-1 | 1 |
| SA206688 | 126-1 | 1 |
| SA206689 | 102-1 | 1 |
| SA206690 | 142-1 | 1 |
| SA206691 | 169-1 | 1 |
| SA206692 | 153-1 | 1 |
| SA206693 | 150-1 | 1 |
| SA206694 | 152-1 | 1 |
| SA206695 | 176-1 | 1 |
| SA206696 | 116-1 | 1 |
| SA206697 | 133-1 | 1 |
| SA206698 | 138-1 | 1 |
| SA206699 | 163-1 | 1 |
| SA206700 | 171-1 | 1 |
| SA206701 | 109-1 | 1 |
| SA206702 | 170-1 | 1 |
| SA206703 | 131-1 | 1 |
| SA206704 | 168-1.5 | 1.5 |
| SA206705 | 176-1.5 | 1.5 |
| SA206706 | 165-1.5 | 1.5 |
| SA206707 | 160-1.5 | 1.5 |
| SA206708 | 155-1.5 | 1.5 |
| SA206709 | 163-1.5 | 1.5 |
| SA206710 | 150-1.5 | 1.5 |
| SA206711 | 148-1.5 | 1.5 |
| SA206712 | 158-1.5 | 1.5 |
| SA206713 | 175-1.5 | 1.5 |
| SA206714 | 152-1.5 | 1.5 |
| SA206715 | 161-1.5 | 1.5 |
| SA206716 | 170-1.5 | 1.5 |
| SA206717 | 145-1.5 | 1.5 |
| SA206718 | 169-1.5 | 1.5 |
| SA206719 | 145-1a | 1a |
| SA206720 | 134-1a | 1a |
| SA206721 | 134-1b | 1b |
| SA206722 | 145-1b | 1b |
| SA206723 | 134-1c | 1c |
| SA206724 | 145-1c | 1c |
Collection:
| Collection ID: | CO002234 |
| Collection Summary: | Stool samples |
| Sample Type: | Feces |
| Storage Conditions: | -80℃ |
Treatment:
| Treatment ID: | TR002253 |
| Treatment Summary: | Patients underwent standard clinical therapy for primary CDI, as prescribed by the clinical teams. No other intervention therapies were included in the study. |
Sample Preparation:
| Sampleprep ID: | SP002247 |
| Sampleprep Summary: | Fecal samples were shipped frozen on fecal collection kits. Materials were placed at -80*C until sent for untargeted metabolomic analyses. |
| Processing Storage Conditions: | -80℃ |
Combined analysis:
| Analysis ID | AN003530 |
|---|---|
| Analysis type | MS |
| Chromatography type | Unspecified |
| Chromatography system | Unspecified |
| Column | Unspecified |
| MS Type | Unspecified |
| MS instrument type | Unspecified |
| MS instrument name | Metabolon |
| Ion Mode | UNSPECIFIED |
| Units | intensity |
Chromatography:
| Chromatography ID: | CH002607 |
| Chromatography Summary: | None available - samples analyzed at Metabolon. |
| Instrument Name: | Unspecified |
| Column Name: | Unspecified |
| Chromatography Type: | Unspecified |
MS:
| MS ID: | MS003288 |
| Analysis ID: | AN003530 |
| Instrument Name: | Metabolon |
| Instrument Type: | Unspecified |
| MS Type: | Unspecified |
| MS Comments: | Global untargeted metabolomics |
| Ion Mode: | UNSPECIFIED |
