Summary of Study ST000252

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000204. The data can be accessed directly via it's Project DOI: 10.21228/M81C7N This work is supported by NIH grant, U2C- DK119886.

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Study IDST000252
Study TitleImpact of recurrent hypoglycemia on brain metabolite profile
Study TypeInsulin treatment in diabetic rats
Study SummaryThe goal of this study is to determine the effect of mild / moderate hypoglycemia on brain metabolism. To achieve this goal insulin-treated diabetic rats will be subjected to recurrent mild / moderate hypoglycemia.
Institute
University of Florida
DepartmentSECIM
Last NameDave
First NameKunjan
EmailKdave@med.miami.edu
Phone305-243-3590
Submit Date2015-08-06
Num Groups2
Total Subjects40
Study CommentsTwo groups (i) Insulin treated diabetic + Recurrent hypoglycemia, (ii) Insulin treated diabetic + Recurrent hypoglycemia (only insulin injection) + Glucose infusion to maintain glucose to baseline levels.Total 40 samples. Description: Ten hippocampus samples and 10 hypothalamus sample from ITD+RH group of rats.Similarly, Ten hippocampus samples and 10 hypothalamus sample from ITD+RH+Glucose group of rats.
Raw Data AvailableYes
Raw Data File Type(s)mzML
Uploaded File Size4.8 G
Analysis Type DetailLC-MS
Release Date2016-12-22
Release Version1
Kunjan Dave Kunjan Dave
https://dx.doi.org/10.21228/M81C7N
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN000398 AN000399
Analysis type MS MS
Chromatography type Reversed phase Reversed phase
Chromatography system Thermo Dionex Ultimate 3000 Thermo Dionex Ultimate 3000
Column ACE Excel 2 C18-PFP (100 x 2.1mm, 2um) ACE Excel 2 C18-PFP (100 x 2.1mm, 2um)
MS Type ESI ESI
MS instrument type Orbitrap Orbitrap
MS instrument name Thermo Q Exactive Orbitrap Thermo Q Exactive Orbitrap
Ion Mode POSITIVE NEGATIVE
Units Peak area Peak Area
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