Summary of Study ST001333

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000910. The data can be accessed directly via it's Project DOI: 10.21228/M82H5K This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001333
Study TitleHuntington’s Disease Genotype Suppresses Global Manganese-Responsive Processes
Study TypeUntargeted metabolomics analysis
Study SummaryGlobal untargeted metabolomics studies performed in the striatum tissue, the brain region most sensitive to neurodegeneration in Huntington’s Disease, to investigate global Mn-dependent and Mn-responsive biology following various Mn exposures in a mouse model of HD.
Institute
Vanderbilt University
DepartmentChemistry
LaboratoryCenter for Innovative Technology
Last NameCodreanu
First NameSimona
Address1234 Stevenson Center Lane
Emailsimona.codreanu@vanderbilt.edu
Phone6158758422
Submit Date2020-03-27
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2020-09-29
Release Version1
Simona Codreanu Simona Codreanu
https://dx.doi.org/10.21228/M82H5K
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN002222
Analysis type MS
Chromatography type HILIC
Chromatography system Vanquish UHPLC binary system
Column SeQuant ZIC-HILIC 3.5-μm, 2.1 mm × 100 mm column
MS Type ESI
MS instrument type Orbitrap
MS instrument name Thermo Q Exactive HF hybrid Orbitrap
Ion Mode POSITIVE
Units peak area

Chromatography:

Chromatography ID:CH001630
Instrument Name:Vanquish UHPLC binary system
Column Name:SeQuant ZIC-HILIC 3.5-μm, 2.1 mm × 100 mm column
Column Temperature:40
Flow Rate:0.2 mL/min
Solvent A:5mM Ammonium formate in 90% water, 10% acetonitrile
Solvent B:5mM Ammonium formate in 90% acetonitrile, 10% water
Chromatography Type:HILIC
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