Summary of Study ST000785

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000571. The data can be accessed directly via it's Project DOI: 10.21228/M8VM2M This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

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Study IDST000785
Study TitlePharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock
Study Typemultiple timepoints; patients with severe sepsis or septic shock
Study Summaryphase I study of L-carnitine infusion for the treatment of vasopressor-dependent shock
Institute
University of Michigan
DepartmentClinical Pharmacy
LaboratoryThe NMR Metabolomics Laboratory (Stringer)
Last NameStringer
First NameKathleen
AddressUniversity Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105
EmailNMRmetabolomics@umich.edu
Phonenone
Submit Date2016-12-08
Num Groups2
Total Subjects31
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2017-10-03
Release Version1
Kathleen Stringer Kathleen Stringer
https://dx.doi.org/10.21228/M8VM2M
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Collection:

Collection ID:CO000802
Collection Summary:Serum collected via existing intravenous or arterial catheter
Collection Protocol Comments:T0: collected before carnitine or placebo administration, T24: collected 24h after administration of L-carnitine or placebo (±4h), T48: collected 48h after administration of L-carnitine or placebo (±4h)
Sample Type:Blood serum
Collection Method:via existing intravenous or arterial catheter
Collection Frequency:1/timepoint, 3 collections/48h
Collection Time:T0: before administration, T24: 24h after administration (±4h), T48: 48h after administration (±4h)
Volumeoramount Collected:10mL
Storage Conditions:Initial RT then -80°C following processing (within 2h of collection)
Collection Vials:SST: Becton-Dickinson 10mL vacutainer Serum Separator tubes
Storage Vials:Sterile 1mL cryovials
Collection Tube Temp:RT
Additives:None
Blood Serum Or Plasma:Serum
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