Summary of Study ST000734

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000531. The data can be accessed directly via it's Project DOI: 10.21228/M81H4W This work is supported by NIH grant, U2C- DK119886.

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Study IDST000734
Study TitleMeasuring SCFA in mice gut following colonization by C. difficile
Study TypeMS analysis
Study Summary3 cages of 5-8 week old C57B/6 mice were placed on the antibiotic cefoperazone for 10 days followed by 2 days of reovery on plain water. One cage remained on plain water the entire time. Of the three antibiotic treated cages. One was mock infected (uninfected control), one was infected with C. difficile strain VPI 10463, while the other was infected with C. difficile strain 630. Twenty-four hours after the infection the mice were eutanized and the ceal content was collected and snap frozen in liquid nitrogen. Samples were stored in the -80 until analysis.
Institute
University of Michigan
DepartmentBiomedical Research Core Facilities
LaboratoryMetabolomics core
Last NameKachman
First NameMaureen
Address6300 Brehm Tower, 1000 Wall Street, Ann Arbor, MI 48105-5714
Emailmkachman@med.umich.edu
Phone(734) 232-8175
Submit Date2017-06-19
Num Groups4
Total Subjects4
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailGC-MS
Release Date2017-12-06
Release Version1
Maureen Kachman Maureen Kachman
https://dx.doi.org/10.21228/M81H4W
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mouse; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id CEFOPERAZONE Infection
SA040994S00022595NO NO
SA040995S00022597NO NO
SA040996S00022596NO NO
SA040997S00022608YES C.difficile 630
SA040998S00022609YES C.difficile 630
SA040999S00022611YES C.difficile 630
SA041000S00022612YES C.difficile 630
SA041001S00022610YES C.difficile 630
SA041002S00022607YES C.difficile VPI 10463
SA041003S00022606YES C.difficile VPI 10463
SA041004S00022604YES C.difficile VPI 10463
SA041005S00022605YES C.difficile VPI 10463
SA041006S00022603YES C.difficile VPI 10463
SA041007S00022599YES NO
SA041008S00022598YES NO
SA041009S00022601YES NO
SA041010S00022602YES NO
SA041011S00022600YES NO
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