Summary of Study ST001140

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000761. The data can be accessed directly via it's Project DOI: 10.21228/M89Q32 This work is supported by NIH grant, U2C- DK119886.

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Study IDST001140
Study TitleChanges in the Canine Plasma Lipidome after Short- and Long-Term Excess Glucocorticoid Exposure
Study SummaryGlucocorticoids (GCs) are widely used in veterinary and human medicine. Chromic endogenous or iatrogenic GC overexposure impairs metabolic function and can result in diverse side-effects, including Cushing’s syndrome. This study examines the effects of experimentally induced short-term and long-term GC excess (induced by prednisolone and tetracosactide, respectively) on the plasma lipidome of Beale dogs. Both, long- and short-term GC resulted in significant changes of the plasma lipidome.
Institute
National University of Singapore;University of Zurich
DepartmentSingapore Lipidomics Incubator (SLING);Vetsuisse Faculty, University of Zurich
LaboratorySingapore Lipidomics Incubator (SLING), National University of Singapore
Last NameBurla
First NameBo
Address28 Medical Drive, Singapore 117456, Singapore
Emailbo.burla@nus.edu.sg
Phone+6565166683
Submit Date2019-01-19
Num Groups2
Total Subjects14
Num Males9
Num Females5
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2019-03-06
Release Version1
Bo Burla Bo Burla
https://dx.doi.org/10.21228/M89Q32
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Canis lupus familiaris (Factor headings shown in green)

mb_sample_id local_sample_id TreatmentGroup TreatmentDuration SamplingTimePoint
SA078299Prednisolone-d0-P5Prednisolone 0d before
SA078300Prednisolone-d0-P6Prednisolone 0d before
SA078301Prednisolone-d0-P1Prednisolone 0d before
SA078302Prednisolone-d0-P4Prednisolone 0d before
SA078303Prednisolone-d0-P7Prednisolone 0d before
SA078304Prednisolone-d0-P8Prednisolone 0d before
SA078305Prednisolone-d0-P2Prednisolone 0d before
SA078306Prednisolone-d0-P3Prednisolone 0d before
SA078307Prednisolone-d4-P4Prednisolone 4d after
SA078308Prednisolone-d4-P1Prednisolone 4d after
SA078309Prednisolone-d4-P7Prednisolone 4d after
SA078310Prednisolone-d4-P8Prednisolone 4d after
SA078311Prednisolone-d4-P2Prednisolone 4d after
SA078312Prednisolone-d4-P3Prednisolone 4d after
SA078313Prednisolone-d4-P6Prednisolone 4d after
SA078314Prednisolone-d4-P5Prednisolone 4d after
SA078315Tetracosactide-w00-T6Tetracosactide 00w before
SA078316Tetracosactide-w00-T5Tetracosactide 00w before
SA078317Tetracosactide-w00-T4Tetracosactide 00w before
SA078318Tetracosactide-w00-T2Tetracosactide 00w before
SA078319Tetracosactide-w00-T1Tetracosactide 00w before
SA078320Tetracosactide-w00-T3Tetracosactide 00w before
SA078321Tetracosactide-w25-T5Tetracosactide 25w after
SA078322Tetracosactide-w25-T6Tetracosactide 25w after
SA078323Tetracosactide-w25-T1Tetracosactide 25w after
SA078324Tetracosactide-w25-T2Tetracosactide 25w after
SA078325Tetracosactide-w25-T3Tetracosactide 25w after
SA078326Tetracosactide-w25-T4Tetracosactide 25w after
Showing results 1 to 28 of 28
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