Summary of Study ST001508

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001017. The data can be accessed directly via it's Project DOI: 10.21228/M87M4S This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001508
Study TitleLiver metabolomics in old liver-specific SIRT6 overexpressing mice
Study SummaryOur previous data had suggested that gluconeogenesis capacity from the precursors lactate and glycerol declines in old C57BL/6 mice. This decline was rescued by whole body SIRT6 overexpression, but not in liver-specific SIRT6 overexpression. Here we preformed liver metabolomics in old liver-specific SIRT6 overexpression and control mice.
Institute
Bar Ilan University
DepartmentThe Mina & Everard Goodman Faculty of Life Sciences
LaboratoryLaboratory of Prof. Haim Cohen
Last NameCohen
First NameChaim
AddressBar Ilan University, Ramat Gan, Israel, 5290002
EmailHaim.Cohen@biu.ac.il
Phone+97235318383
Submit Date2020-10-07
Num Groups4
Total Subjects20
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2021-03-11
Release Version1
Chaim Cohen Chaim Cohen
https://dx.doi.org/10.21228/M87M4S
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Genotype
SA12679307_Liver_CREAlbumin Cre control
SA12679408_Liver_CREAlbumin Cre control
SA12679516_Liver_CREAlbumin Cre control
SA12679604_Liver_CREAlbumin Cre control
SA12679719_Liver_CREAlbumin Cre control
SA12679812_Liver_KISSFlox control
SA12679914_Liver_KISSFlox control
SA12680011_Liver_KISSFlox control
SA12680102_Liver_KISSFlox control
SA12680206_Liver_KISSFlox control
SA12680310_Liver_OELiver specific SIRT6 overexpression
SA12680403_Liver_OELiver specific SIRT6 overexpression
SA12680518_Liver_OELiver specific SIRT6 overexpression
SA12680601_Liver_OELiver specific SIRT6 overexpression
SA12680717_Liver_OELiver specific SIRT6 overexpression
SA12680820_Liver_WTWild-type
SA12680915_Liver_WTWild-type
SA12681009_Liver_WTWild-type
SA12681113_Liver_WTWild-type
SA12681205_Liver_WTWild-type
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