Summary of Study ST001523
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001005. The data can be accessed directly via it's Project DOI: 10.21228/M8SH6G This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001523 |
| Study Title | The effect of fasting and sirtuin overexpression on serum metabolome. |
| Study Type | untargeted metabolomics |
| Study Summary | The levels of the sirtuins SIRT1 and SIRT6 are regulated by nutrient availability in several mammalian tissues. In addition, overexpressing SIRT1 in mice improves healthspan, while SIRT6 overexpression increases both healthspan and lifespan. However, little is known about the impact of these sirtuins at the in vivo metabolomics level. Thus, we performed metabolomics on serum taken from 15 months old male mice overexpressing SIRT1, SIRT6 and SIRT1+SIRT6 as well as WT controls. Sera were obtained from mice at three nutritional time points - at fed state, after 4h morning fast and after 16h fast. |
| Institute | Bar Ilan University |
| Department | The Mina & Everard Goodman Faculty of Life Sciences |
| Laboratory | Laboratory of Prof. Haim Cohen |
| Last Name | Cohen |
| First Name | Haim |
| Address | Bar Ilan University, Ramat Gan, Israel, 5290002 |
| Haim.Cohen@biu.ac.il | |
| Phone | +97235318383 |
| Submit Date | 2020-09-10 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | cdf |
| Analysis Type Detail | GC-MS |
| Release Date | 2021-03-11 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)
| mb_sample_id | local_sample_id | Treamtent group |
|---|---|---|
| SA128376 | (20) 1+6 16h_072 | Sirt1+6 OE - 16h fast |
| SA128377 | (39) 1+6 16h_075 | Sirt1+6 OE - 16h fast |
| SA128378 | (16) 1+6 16h_071 | Sirt1+6 OE - 16h fast |
| SA128379 | (28) 1+6 16h_073 | Sirt1+6 OE - 16h fast |
| SA128380 | (36) 1+6 16h_074 | Sirt1+6 OE - 16h fast |
| SA128381 | (16) 1+6 4h_066 | Sirt1+6 OE - 4h fast |
| SA128382 | (20) 1+6 4h_067 | Sirt1+6 OE - 4h fast |
| SA128383 | (28) 1+6 4h_068 | Sirt1+6 OE - 4h fast |
| SA128384 | (39) 1+6 4h_070 | Sirt1+6 OE - 4h fast |
| SA128385 | (36) 1+6 4h_069 | Sirt1+6 OE - 4h fast |
| SA128386 | (20) 1+6 fed_062 | Sirt1+6 OE - fed |
| SA128387 | (28) 1+6 fed_063 | Sirt1+6 OE - fed |
| SA128388 | (16) 1+6 fed_061 | Sirt1+6 OE - fed |
| SA128389 | (36) 1+6 fed_064 | Sirt1+6 OE - fed |
| SA128390 | (39) 1+6 fed_065 | Sirt1+6 OE - fed |
| SA128355 | (21) 1 16h_039 | Sirt1 OE - 16h fast |
| SA128356 | (8) 1 16h_037 | Sirt1 OE - 16h fast |
| SA128357 | (35) 1 16h_040 | Sirt1 OE - 16h fast |
| SA128358 | (52) 1 16h_041 | Sirt1 OE - 16h fast |
| SA128359 | (55) 1 16h_042 | Sirt1 OE - 16h fast |
| SA128360 | (6) 1 16h_036 | Sirt1 OE - 16h fast |
| SA128361 | (17) 1 16h_038 | Sirt1 OE - 16h fast |
| SA128362 | (35) 1 4h_033 | Sirt1 OE - 4h fast |
| SA128363 | (17) 1 4h_031 | Sirt1 OE - 4h fast |
| SA128364 | (8) 1 4h_030 | Sirt1 OE - 4h fast |
| SA128365 | (6) 1 4h_029 | Sirt1 OE - 4h fast |
| SA128366 | (52) 1 4h_034 | Sirt1 OE - 4h fast |
| SA128367 | (21) 1 4h_032 | Sirt1 OE - 4h fast |
| SA128368 | (55) 1 4h_035 | Sirt1 OE - 4h fast |
| SA128369 | (55) 1 fed_028 | Sirt1 OE - fed |
| SA128370 | (6) 1 fed_022 | Sirt1 OE - fed |
| SA128371 | (17) 1 fed_024 | Sirt1 OE - fed |
| SA128372 | (21) 1 fed_025 | Sirt1 OE - fed |
| SA128373 | (35) 1 fed_026 | Sirt1 OE - fed |
| SA128374 | (52) 1 fed_027 | Sirt1 OE - fed |
| SA128375 | (8) 1 fed_023 | Sirt1 OE - fed |
| SA128391 | (14) 6 16h_056 | Sirt6 OE - 16h fast |
| SA128392 | (13) 6 16h_055 | Sirt6 OE - 16h fast |
| SA128393 | (19) 6 16h_058 | Sirt6 OE - 16h fast |
| SA128394 | (15) 6 16h_057 | Sirt6 OE - 16h fast |
| SA128395 | (29) 6 16h_059 | Sirt6 OE - 16h fast |
| SA128396 | (38) 6 16h_060 | Sirt6 OE - 16h fast |
| SA128397 | (19) 6 4h_052 | Sirt6 OE - 4h fast |
| SA128398 | (15) 6 4h_051 | Sirt6 OE - 4h fast |
| SA128399 | (38) 6 4h_054 | Sirt6 OE - 4h fast |
| SA128400 | (14) 6 4h_050 | Sirt6 OE - 4h fast |
| SA128401 | (29) 6 4h_053 | Sirt6 OE - 4h fast |
| SA128402 | (13) 6 4h_049 | Sirt6 OE - 4h fast |
| SA128403 | (15) 6 fed_045 | Sirt6 OE - fed |
| SA128404 | (14) 6 fed_044 | Sirt6 OE - fed |
| SA128405 | (19) 6 fed_046 | Sirt6 OE - fed |
| SA128406 | (13) 6 fed_043 | Sirt6 OE - fed |
| SA128407 | (29) 6 fed_047 | Sirt6 OE - fed |
| SA128408 | (38) 6 fed_048 | Sirt6 OE - fed |
| SA128409 | (18) WT 16h_017 | WT - 16h fast |
| SA128410 | (7) WT 16h_015 | WT - 16h fast |
| SA128411 | (65) WT 16h_021 | WT - 16h fast |
| SA128412 | (9) WT 16h_016 | WT - 16h fast |
| SA128413 | (48) WT 16h_019 | WT - 16h fast |
| SA128414 | (27) WT 16h_018 | WT - 16h fast |
| SA128415 | (56) WT 16h_020 | WT - 16h fast |
| SA128416 | (65) WT 4h_014 | WT - 4h fast |
| SA128417 | (48) WT 4h_012 | WT - 4h fast |
| SA128418 | (18) WT 4h_010 | WT - 4h fast |
| SA128419 | (9) WT 4h_009 | WT - 4h fast |
| SA128420 | (27) WT 4h_011 | WT - 4h fast |
| SA128421 | (56) WT 4h_013 | WT - 4h fast |
| SA128422 | (7) WT 4h_008 | WT - 4h fast |
| SA128423 | (9) WT fed_002 | WT - Fed |
| SA128424 | (18) WT fed_003 | WT - Fed |
| SA128425 | (65) WT fed_007 | WT - Fed |
| SA128426 | (7) WT fed_001 | WT - Fed |
| SA128427 | (56) WT fed_006 | WT - Fed |
| SA128428 | (48) WT fed_005 | WT - Fed |
| SA128429 | (27) WT fed_004 | WT - Fed |
| Showing results 1 to 75 of 75 |
