Summary of study ST001745

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001118. The data can be accessed directly via it's Project DOI: 10.21228/M86404 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001745
Study TitleMetabolomic profiling of the rat hippocampus across developmental ages and after learning
Study TypeDevelopmental study
Study SummaryLittle is known about how the hippocampal metabolomic profile changes across development and in response to learning at different ages. To fill this knowledge gap, we employed an untargeted metabolomic analyses in rats to determine how the hippocampal metabolome changes over the course of post-natal development under basal conditions and following inhibitory avoidance (IA) training, an aversive episodic event. We found that unique metabolomic profiles accompany learning at different ages. Subsequent biochemical and behavioral studies based on unique metabolomic regulations in the infant hippocampus established that infantile learning selectively recruits the glutathione-mediated antioxidant defenses for the formation of infantile memory.
Institute
New York University
DepartmentCenter for Neural Science (NYU)
LaboratoryCristina Alberini
Last NameBessieres
First NameBenjamin
Address4 Washington Place, Room 623
Emailbjb11@nyu.edu
Phone6315684274
Submit Date2021-03-26
Num Groups8
Total Subjects52
Num Males35
Num Females17
Raw Data AvailableYes
Raw Data File Type(s).xls
Analysis Type DetailESIOther
Release Date2021-05-01
Release Version1
Benjamin Bessieres Benjamin Bessieres
https://dx.doi.org/10.21228/M86404
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id local_sample_id Treatment
SA163301NYSM-00454naive
SA163302NYSM-00481naive
SA163303NYSM-00482naive
SA163304NYSM-00479naive
SA163305NYSM-00478naive
SA163306NYSM-00476naive
SA163307NYSM-00477naive
SA163308NYSM-00483naive
SA163309NYSM-00492naive
SA163310NYSM-00496naive
SA163311NYSM-00497naive
SA163312NYSM-00498naive
SA163313NYSM-00495naive
SA163314NYSM-00494naive
SA163315NYSM-00475naive
SA163316NYSM-00493naive
SA163317NYSM-00484naive
SA163318NYSM-00480naive
SA163319NYSM-00461naive
SA163320NYSM-00459naive
SA163321NYSM-00458naive
SA163322NYSM-00463naive
SA163323NYSM-00457naive
SA163324NYSM-00460naive
SA163325NYSM-00462naive
SA163326NYSM-00472naive
SA163327NYSM-00455naive
SA163328NYSM-00471naive
SA163329NYSM-00470naive
SA163330NYSM-00469naive
SA163331NYSM-00456naive
SA163332NYSM-00502trained
SA163333NYSM-00504trained
SA163334NYSM-00505trained
SA163335NYSM-00503trained
SA163336NYSM-00501trained
SA163337NYSM-00500trained
SA163338NYSM-00499trained
SA163339NYSM-00489trained
SA163340NYSM-00466trained
SA163341NYSM-00465trained
SA163342NYSM-00467trained
SA163343NYSM-00468trained
SA163344NYSM-00474trained
SA163345NYSM-00464trained
SA163346NYSM-00485trained
SA163347NYSM-00473trained
SA163348NYSM-00490trained
SA163349NYSM-00488trained
SA163350NYSM-00487trained
SA163351NYSM-00486trained
SA163352NYSM-00491trained
Showing results 1 to 52 of 52
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