Summary of Study ST003500
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002146. The data can be accessed directly via it's Project DOI: 10.21228/M8783Z This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST003500 |
Study Title | A UHPLC-MS/MS Method for Profiling of Urinary Mercapturic Acids using Positive Ion Mode |
Study Summary | We report the first application of a UHPLC-MS/MS method using positive ion mode detection for the unbiased characterization of mercapturic acids. The proposed method utilizes a neutral loss monitoring paradigm to monitor for two diagnostic fragmentation pathways for this class of compound. Using a cohort of 20 nonsmokers and 20 smokers, we detected 180 putative mercapturic acid signatures that exhibited a high degree of reproducibility from the complex urine metabolome background. Following a combination of multivariate and univariate statistics, we found 33 putative mercapturic acids associated with smoking status. |
Institute | University of Minnesota |
Last Name | Murray |
First Name | Kevin |
Address | 2-210 CCRB, 2231 6th St SE, Minneapolis, MN 55455 |
murra668@umn.edu | |
Phone | 612-626-2182 |
Submit Date | 2024-08-01 |
Num Groups | 2 |
Total Subjects | 20 |
Raw Data Available | Yes |
Raw Data File Type(s) | mzML |
Analysis Type Detail | LC-MS |
Release Date | 2025-02-03 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)
mb_sample_id | local_sample_id | Sample source | Smoking Status |
---|---|---|---|
SA385691 | N149 | Urine | Non-Smoker |
SA385692 | N082 | Urine | Non-Smoker |
SA385693 | N215 | Urine | Non-Smoker |
SA385694 | N207 | Urine | Non-Smoker |
SA385695 | N194 | Urine | Non-Smoker |
SA385696 | N189 | Urine | Non-Smoker |
SA385697 | N167 | Urine | Non-Smoker |
SA385698 | N162 | Urine | Non-Smoker |
SA385699 | N161 | Urine | Non-Smoker |
SA385700 | N079 | Urine | Non-Smoker |
SA385701 | N142 | Urine | Non-Smoker |
SA385702 | N087 | Urine | Non-Smoker |
SA385703 | N140 | Urine | Non-Smoker |
SA385704 | N134 | Urine | Non-Smoker |
SA385705 | N133 | Urine | Non-Smoker |
SA385706 | N128 | Urine | Non-Smoker |
SA385707 | N096 | Urine | Non-Smoker |
SA385708 | N094 | Urine | Non-Smoker |
SA385709 | N088 | Urine | Non-Smoker |
SA385710 | N141 | Urine | Non-Smoker |
SA385711 | pool_10 | Urine | QC |
SA385712 | pool_09 | Urine | QC |
SA385713 | pool_08 | Urine | QC |
SA385714 | pool_07 | Urine | QC |
SA385715 | pool_06 | Urine | QC |
SA385716 | pool_05 | Urine | QC |
SA385717 | pool_03 | Urine | QC |
SA385718 | pool_02 | Urine | QC |
SA385719 | pool_01 | Urine | QC |
SA385720 | pool_04 | Urine | QC |
SA385721 | S147 | Urine | Smoker |
SA385722 | S190 | Urine | Smoker |
SA385723 | S171 | Urine | Smoker |
SA385724 | S163 | Urine | Smoker |
SA385725 | S157 | Urine | Smoker |
SA385726 | S156 | Urine | Smoker |
SA385727 | S152 | Urine | Smoker |
SA385728 | S151 | Urine | Smoker |
SA385729 | S150 | Urine | Smoker |
SA385730 | S144 | Urine | Smoker |
SA385731 | S146 | Urine | Smoker |
SA385732 | S145 | Urine | Smoker |
SA385733 | S138 | Urine | Smoker |
SA385734 | S136 | Urine | Smoker |
SA385735 | S135 | Urine | Smoker |
SA385736 | S132 | Urine | Smoker |
SA385737 | S131 | Urine | Smoker |
SA385738 | S117 | Urine | Smoker |
SA385739 | S102 | Urine | Smoker |
SA385740 | S110 | Urine | Smoker |
Showing results 1 to 50 of 50 |