Summary of Study ST003554
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR002188. The data can be accessed directly via it's Project DOI: 10.21228/M8SV5J This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST003554 |
| Study Title | Investigation of age-dependent changes in the brain of honeybee workers using targeted metabolomics for amino acid and biogenic amine determination |
| Study Summary | In the honeybee guts we measured the concentrations of 21 amino acids and 6 biogenic amines. Using a k-means clustering, the metabolites were grouped by their trends into six clusters. Tyramine and tyrosine are involved in the octopamine and dopamine biosynthesis. We found that all four metabolites were part of the same cluster, with their concentrations being significantly decreased in comparison to newly emerged workers from day 1 onwards for the entire duration of the study. |
| Institute | Helmholtz Centre for Environmental Research |
| Department | Molecular Systems Biology |
| Last Name | Engelmann |
| First Name | Beatrice |
| Address | Permoserstraße 15, Leipzipg, Saxony, 03418, Germany |
| beatrice.engelmann@ufz.de | |
| Phone | 004934160251099 |
| Submit Date | 2024-10-28 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | wiff |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-11-27 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Insect; Subject species: Apis mellifera (Factor headings shown in green)
| mb_sample_id | local_sample_id | life stage | age of workers in days | Sample source |
|---|---|---|---|---|
| SA388307 | H2_D1_3_diluted | establishment | 1 | brain |
| SA388308 | H1_D1_3_diluted | establishment | 1 | brain |
| SA388309 | H1_D1_4_diluted | establishment | 1 | brain |
| SA388310 | H1_D1_5_diluted | establishment | 1 | brain |
| SA388311 | H2_D1_1 | establishment | 1 | brain |
| SA388312 | H2_D1_2 | establishment | 1 | brain |
| SA388313 | H2_D1_3 | establishment | 1 | brain |
| SA388314 | H2_D1_4 | establishment | 1 | brain |
| SA388315 | H2_D1_5 | establishment | 1 | brain |
| SA388316 | H2_D1_1_diluted | establishment | 1 | brain |
| SA388317 | H2_D1_2_diluted | establishment | 1 | brain |
| SA388318 | H2_D1_5_diluted | establishment | 1 | brain |
| SA388319 | H1_D1_1_diluted | establishment | 1 | brain |
| SA388320 | H3_D1_1 | establishment | 1 | brain |
| SA388321 | H3_D1_2 | establishment | 1 | brain |
| SA388322 | H3_D1_3 | establishment | 1 | brain |
| SA388323 | H3_D1_4 | establishment | 1 | brain |
| SA388324 | H3_D1_5 | establishment | 1 | brain |
| SA388325 | H3_D1_1_diluted | establishment | 1 | brain |
| SA388326 | H3_D1_2_diluted | establishment | 1 | brain |
| SA388327 | H3_D1_3_diluted | establishment | 1 | brain |
| SA388328 | H3_D1_4_diluted | establishment | 1 | brain |
| SA388329 | H3_D1_5_diluted | establishment | 1 | brain |
| SA388330 | H1_D1_2_diluted | establishment | 1 | brain |
| SA388331 | H2_D1_4_diluted | establishment | 1 | brain |
| SA388332 | H1_D1_5 | establishment | 1 | brain |
| SA388333 | H1_D1_4 | establishment | 1 | brain |
| SA388334 | H1_D1_3 | establishment | 1 | brain |
| SA388335 | H1_D1_1 | establishment | 1 | brain |
| SA388336 | H1_D1_2 | establishment | 1 | brain |
| SA388337 | H2_D3_3 | establishment | 3 | brain |
| SA388338 | H2_D3_2 | establishment | 3 | brain |
| SA388339 | H2_D3_1 | establishment | 3 | brain |
| SA388340 | H2_D3_3_diluted | establishment | 3 | brain |
| SA388341 | H3_D3_1_diluted | establishment | 3 | brain |
| SA388342 | H2_D3_4 | establishment | 3 | brain |
| SA388343 | H2_D3_5 | establishment | 3 | brain |
| SA388344 | H3_D3_2_diluted | establishment | 3 | brain |
| SA388345 | H3_D3_3_diluted | establishment | 3 | brain |
| SA388346 | H3_D3_4_diluted | establishment | 3 | brain |
| SA388347 | H3_D3_5_diluted | establishment | 3 | brain |
| SA388348 | H1_D3_2 | establishment | 3 | brain |
| SA388349 | H1_D3_1 | establishment | 3 | brain |
| SA388350 | H2_D3_2_diluted | establishment | 3 | brain |
| SA388351 | H2_D3_5_diluted | establishment | 3 | brain |
| SA388352 | H1_D3_2_diluted | establishment | 3 | brain |
| SA388353 | H2_D3_1_diluted | establishment | 3 | brain |
| SA388354 | H1_D3_3 | establishment | 3 | brain |
| SA388355 | H2_D3_4_diluted | establishment | 3 | brain |
| SA388356 | H3_D3_5 | establishment | 3 | brain |
| SA388357 | H3_D3_4 | establishment | 3 | brain |
| SA388358 | H3_D3_3 | establishment | 3 | brain |
| SA388359 | H3_D3_2 | establishment | 3 | brain |
| SA388360 | H3_D3_1 | establishment | 3 | brain |
| SA388361 | H1_D3_1_diluted | establishment | 3 | brain |
| SA388362 | H1_D3_3_diluted | establishment | 3 | brain |
| SA388363 | H1_D3_4_diluted | establishment | 3 | brain |
| SA388364 | H1_D3_5_diluted | establishment | 3 | brain |
| SA388365 | H1_D3_4 | establishment | 3 | brain |
| SA388366 | H1_D3_5 | establishment | 3 | brain |
| SA388367 | H2_D5_1_diluted | establishment | 5 | brain |
| SA388368 | H2_D5_5_diluted | establishment | 5 | brain |
| SA388369 | H3_D5_5 | establishment | 5 | brain |
| SA388370 | H2_D5_4_diluted | establishment | 5 | brain |
| SA388371 | H2_D5_3_diluted | establishment | 5 | brain |
| SA388372 | H2_D5_2_diluted | establishment | 5 | brain |
| SA388373 | H2_D5_4 | establishment | 5 | brain |
| SA388374 | H1_D5_1 | establishment | 5 | brain |
| SA388375 | H2_D5_5 | establishment | 5 | brain |
| SA388376 | H3_D5_4 | establishment | 5 | brain |
| SA388377 | H2_D5_3 | establishment | 5 | brain |
| SA388378 | H3_D5_1_diluted | establishment | 5 | brain |
| SA388379 | H3_D5_3 | establishment | 5 | brain |
| SA388380 | H3_D5_2 | establishment | 5 | brain |
| SA388381 | H3_D5_1 | establishment | 5 | brain |
| SA388382 | H1_D5_1_diluted | establishment | 5 | brain |
| SA388383 | H1_D5_2_diluted | establishment | 5 | brain |
| SA388384 | H1_D5_3_diluted | establishment | 5 | brain |
| SA388385 | H1_D5_4_diluted | establishment | 5 | brain |
| SA388386 | H1_D5_5_diluted | establishment | 5 | brain |
| SA388387 | H3_D5_5_diluted | establishment | 5 | brain |
| SA388388 | H3_D5_4_diluted | establishment | 5 | brain |
| SA388389 | H3_D5_3_diluted | establishment | 5 | brain |
| SA388390 | H3_D5_2_diluted | establishment | 5 | brain |
| SA388391 | H1_D5_2 | establishment | 5 | brain |
| SA388392 | H2_D5_2 | establishment | 5 | brain |
| SA388393 | H1_D5_5 | establishment | 5 | brain |
| SA388394 | H1_D5_4 | establishment | 5 | brain |
| SA388395 | H1_D5_3 | establishment | 5 | brain |
| SA388396 | H2_D5_1 | establishment | 5 | brain |
| SA388397 | H3_EF_4 | experienced_forager | >12 | brain |
| SA388398 | H3_EF_3 | experienced_forager | >12 | brain |
| SA388399 | H3_EF_2 | experienced_forager | >12 | brain |
| SA388400 | H3_EF_1 | experienced_forager | >12 | brain |
| SA388401 | H2_EF_1_diluted | experienced_forager | >12 | brain |
| SA388402 | H2_EF_2_diluted | experienced_forager | >12 | brain |
| SA388403 | H2_EF_3_diluted | experienced_forager | >12 | brain |
| SA388404 | H2_EF_4_diluted | experienced_forager | >12 | brain |
| SA388405 | H2_EF_5_diluted | experienced_forager | >12 | brain |
| SA388406 | H3_EF_5 | experienced_forager | >12 | brain |
