Summary of Study ST000056
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000053. The data can be accessed directly via it's Project DOI: 10.21228/M8C883 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000056 |
| Study Title | Environmental impact on metabolomics and food allergy |
| Study Type | Metabolomics |
| Study Summary | This metabolomics pilot and feasibility (P&F) was conducted to determine if varying the levels of environmental LPS exposure and immunization with the vaccine adjuvant alum alters host metabolism. Additionally, the metabolomics will identify biomarkers that can predict allergic disease development and or disease severity after a peanut challenge in hypersensitive mice. Information gained from the proposed studies may allow for the identification of individuals who are at risk or not at risk for the development of allergic disease. Furthermore, completion of these studies may lead to identification of biological targets that may be used to develop novel therapies to treat or prevent allergic disease via future funding. |
| Institute | University of North Carolina |
| Department | Systems and Translational Sciences |
| Laboratory | Sumner Lab |
| Last Name | Sumner |
| First Name | Susan |
| Address | Eastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081 |
| susan_sumner @unc.edu | |
| Phone | 704-250-5066 |
| Submit Date | 2014-05-31 |
| Num Groups | 2 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | fid |
| Uploaded File Size | 68 M |
| Analysis Type Detail | NMR |
| Release Date | 2015-06-01 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
NMR:
| NMR ID: | NM000026 |
| Analysis ID: | AN000094 |
| Instrument Name: | Bruker Avance III |
| Instrument Type: | FT-NMR |
| NMR Experiment Type: | 1D 1H |
| NMR Comments: | Intellegent binning with 50% looseness |
| Field Frequency Lock: | Deuterium |
| Standard Concentration: | 0.5mM |
| Spectrometer Frequency: | 700 MHz |
| NMR Probe: | cryogenically cooled ATMA inverse probe |
| NMR Solvent: | 10 % D2O |
| NMR Tube Size: | 5mm |
| Shimming Method: | Gradient |
| Pulse Sequence: | noesypr1d |
| Water Suppression: | yes |
| Pulse Width: | 10.7 microseconds |
| Power Level: | 25.704 W |
| Receiver Gain: | 4.5 |
| Offset Frequency: | 3296.0 Hz |
| Chemical Shift Ref Cpd: | DSS |
| Temperature: | 25 degrees celsius |
| Number Of Scans: | 128 |
| Dummy Scans: | 4 |
| Acquisition Time: | 2.324 seconds |
| Relaxation Delay: | 2 s |
| Spectral Width: | 20.13580048 |
| Num Data Points Acquired: | 65536 |
| Real Data Points: | 65536 |
| Line Broadening: | 0.5 |
| Zero Filling: | yes |
| Apodization: | Lorentzian |
| Baseline Correction Method: | Polynomial |
| Chemical Shift Ref Std: | DSS |
