Summary of Study ST000255
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000207. The data can be accessed directly via it's Project DOI: 10.21228/M8N30T This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000255 |
| Study Title | NIH WCMC Pilot & Feasibility Project: “Metabolomics of Neonatal Pulmonary Hypertension” in human |
| Study Type | Case-control study |
| Study Summary | Targeted metabolomic analyses of oxylipins were performed on 40 human umbilical cord plasma samples collected from infants born prematurely (gestational age <37 weeks). Samples were analyzed by UPLC-MS/MS using a Waters Acquity UPLC and detected on an API 4000 QTrap (AB Sciex, Framingham, MA, USA) by multiple reaction monitoring (MRM) after negative mode electrospray ionization. |
| Institute | University of California, Davis |
| Department | Nutrition |
| Laboratory | Newman Lab |
| Last Name | Newman |
| First Name | John |
| Address | 430 W. Health Sciences Dr., Davis, CA 95616 |
| john.newman@ars.usda.gov | |
| Phone | +1-530-752-1009 |
| Submit Date | 2015-09-03 |
| Num Groups | 4 |
| Total Subjects | 16 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML |
| Uploaded File Size | 32 M |
| Analysis Type Detail | LC-MS |
| Release Date | 2015-09-14 |
| Release Version | 1 |
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Project:
| Project ID: | PR000207 |
| Project DOI: | doi: 10.21228/M8N30T |
| Project Title: | Metabolomics of Neonatal Pulmonary Hypertension (in Preterm Infants) |
| Project Type: | Case-control study |
| Project Summary: | This study aimed to determine metabolic patterns in cord blood associated with the development of pulmonary hypertension (PH) in human preterm infants. Umbilical cord blood was acquired from a nested case-control study of 20 premature (gestational age <37 weeks) infants with PH (cases) and 20 infants without PH (controls) selected from Prentice NICU birth cohort. Case and control infants were matched by race/ethnicity, gender, and gestational age. Archived cord blood plasma underwent metabolomics analysis. |
| Institute: | University of California, Davis |
| Department: | Department of Pediatrics, School of Medicine |
| Laboratory: | Wedgwood lab |
| Last Name: | Wedgwood |
| First Name: | Stephen |
| Address: | 1002B, Research II, 4625 2nd Ave., Sacramento, CA 95817 |
| Email: | stephen.wedwood@ucdmc.ucdavis.edu |
| Phone: | +1-916-734-1518 |
| Funding Source: | National Institute of Health U24 DK092993 |
