Summary of Study ST000785
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000571. The data can be accessed directly via it's Project DOI: 10.21228/M8VM2M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000785 |
| Study Title | Pharmacometabolomics of L-Carnitine Treatment Response Phenotypes in Patients with Septic Shock |
| Study Type | multiple timepoints; patients with severe sepsis or septic shock |
| Study Summary | phase I study of L-carnitine infusion for the treatment of vasopressor-dependent shock |
| Institute | University of Michigan |
| Department | Clinical Pharmacy |
| Laboratory | The NMR Metabolomics Laboratory (Stringer) |
| Last Name | Stringer |
| First Name | Kathleen |
| Address | University Michigan, 2900 Huron Parkway, Ann Arbor, MI 48105 |
| NMRmetabolomics@umich.edu | |
| Phone | none |
| Submit Date | 2016-12-08 |
| Num Groups | 2 |
| Total Subjects | 31 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | fid |
| Analysis Type Detail | NMR |
| Release Date | 2017-10-03 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Subject:
| Subject ID: | SU000808 |
| Subject Type: | Human |
| Subject Species: | Homo sapiens |
| Taxonomy ID: | 9606 |
| Age Or Age Range: | 39-93 years |
| Weight Or Weight Range: | 55-130 KG |
| Gender: | males and females |
| Human Race: | Caucasian (C) and African American (AA) |
| Human Inclusion Criteria: | Suspicion of or confirmed infection; two or more systemic infmammatory response syndrome criteria; hypotension requiring vasopressors despite volume resuscitation; a cumulative vasopressor index of 3 or more after 4 hours of administration; and a SOFA score of at least 5. |
| Human Exclusion Criteria: | Age less than 18; greater than 16h after septic shock recognition; a Do Not Resuscitate order; or known inborn error of metaboloism. |
| Species Group: | Human |
