Summary of Study ST000556

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000407. The data can be accessed directly via it's Project DOI: 10.21228/M8FG7D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST000556
Study TitleIROA feasibility project; plasticizers as obesogens in zebrafish
Study Type(1) IROA label (2) Zebrafish exposed to DEHP
Study SummaryZebrafish were fed IROA labelled nematodes (smaple 1-4); In a second experiment, zebrafish larvae were exposed to DEHP, a chemical that is a suspected obesogen.
Institute
University of Florida
DepartmentSECIM
Last NameMartyniuk
First NameChris
Address2187 Mowry Rd. Bldg 471
Emailcmartyn@ufl.edu
Phone352-294-4636
Submit Date2017-01-26
Num Groups2
Total Subjects20
Study CommentsExpt 2: Two groups (control) + DEHP-treated (n=10 larvae pools or biological replicates)
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2018-02-07
Release Version1
Chris Martyniuk Chris Martyniuk
https://dx.doi.org/10.21228/M8FG7D
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR000592
Treatment Summary:Expt 2: Larval zebrafish were exposed to a plastic for 96 hours.
Treatment Compound:DEHP (a plastic)
Treatment Route:waterborne
Treatment Dose:10 uM DEHP
Treatment Doseduration:96 hours
Treatment Vehicle:DMSO
Animal Vet Treatments:None
Animal Anesthesia:Tricaine
Animal Fasting:Early stage larval fish, do not feed for first 144 hours.
Animal Endp Euthanasia:MS-222 or Tricaine
Animal Endp Tissue Coll List:Whole larval fish placed into a vial. Five fish per vial.
Animal Endp Clinical Signs:No clinical signs
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