Summary of all projects

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Project Title
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PR002038 Interaction between NSCLC cells, CD8+ T cells and immune checkpoint inhibitors potentiates coagulation and promotes metabolic remodeling- new cues on CAT-VTE ITQB NOVA ITQB NOVA 1
PR002033 Phosphate availability conditions caspofungin tolerance, capsule attachment and titan cell formation in Cryptococcus neoformans Life Sciences Institute, The University of British Columbia University of British Columbia 1
PR002030 Metabolomic changes in mouse tissues following modulation of serine through the diet Salk Institute Salk Institute for Biological Studies 6
PR002026 SLC25A48 controls mitochondrial choline import and metabolism Beth Israel Deaconess Medical Center Harvard Medical School 1
PR002024 A Covalent Creatine Kinase Inhibitor Ablates Glioblastoma Migration and Sensitizes Tumors to Oxidative Stress Northwestern University, Feinberg School of Medicine Northwestern University, Feinberg School of Medicine 1
PR002023 Iron(III)-salophene catalyzes redox cycles that induce phospholipid peroxidation and deplete cancer cells of ferroptosis-protecting cofactors University of Innsbruck University of Innsbruck 2
PR002020 Analysis of Pasture-Fed vs Grain-Fed Meat in North American Ruminants Duke University Duke University 1
PR002018 Temperature change elicits lipidome adaptation in the simple organisms Mycoplasma mycoides and JCVI-syn3B TU Dresden TU Dresden 1
PR002017 Mitochondrial respiration in microglia is essential for response to demyelinating injury but not proliferation. Northwestern University Feinberg School of Medicine Northwestern University 1
PR002015 Zeb1-mediated control of the phospholipid PUFA/MUFA ratio in EMT/plasticity-associated 1 cancer cell ferroptosis University of Innsbruck University of Innsbruck 4
PR002014 Suppression of prostaglandin I2–type I interferon axis induces extramedullary hematopoiesis to promote cardiac repair after myocardial infarction Tianjin Medical University Tianjin Medical University 1
PR002013 Glutathione synthesis in the mouse liver supports lipid abundance through NRF2 repression. University of Rochester Medical Center University of Rochester Medical Center 6
PR002011 Lipidomic analysis of Axon Regeneration in Xenopus laevis Chiasm University of Miami University of Miami 3
PR002008 Obesity, sex, and depot drive distinct lipid profiles in murine white adipose tissue University of Utah University of Utah 1
PR002005 Protein restriction slows the development and progression of Alzheimer's disease in mice University of Wisconsin-Madison University of Wisconsin-Madison 1
PR002002 Fetal growth delay caused by loss of non-canonical imprinting is resolved late in pregnancy and culminates in offspring overgrowth Hudson Institute of Medical Research Hudson Institute of Medical Research 1
PR002001 Untargeted metabolomics analysis on single cells and cell clusters of TNBC cell lines using mass spectrometry NanJing Medical University Nanjing Medical University 1
PR001998 CAR-T therapy metabolomic study UNIVERSITY OF SALENTO UNIVERSITY OF SALENTO 1
PR001997 Metabolomic investigation of tear fluid biomarkers Institute for Global Food Security Institute for Global Food Security 1
PR001995 Molecular signatures of xenograft colon cancer models treated with topotecan: A Mass Spectrometry-Based Study Sharjah Institute for Medical Research Sharjah Institute for Medical Research 1
PR001989 Proteo-metabolomics and patient tumor slice functional studies point to the centrality of amino acids for re-wired mitochondria in fibrolamellar carcinoma Cornell University Cornell University 1
PR001986 A clade of receptor-like cytoplasmic kinases and 14-3-3 proteins coordinate the inositol hexaphosphate accumulation zhejiang University Zhejiang University 1
PR001985 Serum metabolites for septic shock detection in emergency department National Taiwan University National Taiwan University 1
PR001983 A multimodal drug-diet-immunotherapy combination restrains melanoma progression and metastasis University of Colorado Anschutz Medical Campus University of Colorado Anschutz Medical Campus 2
PR001981 METTL3-mediated chromatin contacts promote stress granule phase separation through metabolic reprogramming during senescence University of Texas MD Anderson Cancer Center University of Texas MD Anderson Cancer Center 1
PR001980 Depression symptoms modifies differently plasma metabolites in pre- and post-menopausal women Universidade Federal de São Paulo Federal University of São Paulo 1
PR001978 Property and Activity Refinement of Dihydroquinazolinone-3-carboxamides as Orally Efficacious Antimalarials that Target PfATP4 Monash University Monash University 1
PR001977 Deep phenotyping of Post-infectious Myalgic Encephalomyelitis/Chronic Fatigue Syndrome National Institutes of Health National Institutes of Health 1
PR001976 A Longitudinal Study in Rheumatoid Arthritis Unveils Metabolomic Biomarkers Preceding Clinical Onset, Assessing Disease Severity, and Anticipating Treatment Response to csDMARDs Department of Rheumatology and Immunology, West China Hospital,Sichuan University, Chengdu, Sichuan, China West China Hospital of Sichuan University 1
PR001974 Inactivation of mitochondrial MUL1 E3 ubiquitin ligase inhibits lipogenesis and prevents diet-induced obesity in mice University of Florida University of Florida 1
PR001973 Assessment and partial characterization of candidate genes in dihydrochalcone and arbutin biosynthesis in an apple-pear hybrid by de novo transcriptome assembly Fondazione Edmund Mach Fondazione Edmund Mach 1
PR001972 Untargeted Metabolomic Profile Of Chili Pepper (Capsicum Chinensed) Developmental Cycle University of Alberta University of Alberta 1
PR001971 Comberhincive Chemometric Metabolomic Profile for Maple Syrup Urine Disease Sick Patients King Saud University King Saud University 1
PR001970 Releasing the mitochondrial respiration brake MCJ/DnaJC15 enhances CD8 CAR-T cell therapy efficacy University of Colorado School of Medicine University of Colorado School of Medicine 4
PR001969 Spatial Lipidomics Maps Brain Alterations Associated with Mild Traumatic Brain Injury. Georgia Institute of Technology Georgia Institute of Technology 1
PR001967 Loss of dihydroceramide desaturase drives neurodegeneration by disrupting endoplasmic reticulum and lipid droplet homeostasis in glial cells Washington University in St. Louis Washington University in St. Louis 1
PR001966 Diet-omics in the Study of Urban and Rural Crohn disease Evolution (SOURCE) cohort Sheba hospital Sheba hospital 1
PR001965 New class of heterospirocyclic compounds present strong and rapid activity against artemisinin- and multidrug-resistant P. falciparum parasites Monash University Monash University 1
PR001964 Untargeted serum metabolomics in the Parkinson's Environment and Genes (PEG) Study University of California Los Angeles University of California, Los Angeles 1
PR001961 NMR-based metabolomics combined with metabolic pathway analysis reveals metabolic heterogeneity of colorectal cancer tissue at different anatomical locations and stages Radiology Department, Second Affiliated Hospital, Shantou University Medical College, Shantou Radiology Department, Second Affiliated Hospital, Shantou University Medical College, Shantou 1
PR001960 Nucleotide metabolism of tumor interstitial fluid in one murine model of pancreatic cancer VIB Center for Cancer Biology VIB-KU Leuven Center for Cancer Biology 1
PR001958 Impact of early-life exposure to a potent aryl hydrocarbon receptor ligand on gut microbiota and host glucose homeostasis in C57BL/6J male mice Pennsylvania State University Pennsylvania State University 2
PR001955 On-target, dual aminopeptidase inhibition provides cross-1 species antimalarial activity Monash University Monash University 1
PR001954 Mitochondrial complex I promotes kidney cancer metastasis University of Texas Southwestern Medical Center at Dallas University of Texas Southwestern Medical Center at Dallas 1
PR001953 Global Lipidomics of Serum Samples from control and ACOX1-LKO Mouse Washington University School of Medicine Washington University in St. Louis 1
PR001947 Targeting SOX13 inhibits the assembly of respiratory chain supercomplexes to overcome ferroptosis-resistance in gastric cancer Fudan University Shanghai Cancer Center Fudan University Shanghai Cancer Center 1
PR001945 The microbiota drives diurnal rhythms in tryptophan metabolism in the stressed gut University College Cork University College Cork 2
PR001944 High fat diet ameliorates mitochondrial cardiomyopathy in CHCHD10 mutant mice Weill Cornell Medicine Weill Cornell Medicine 3
PR001943 Pulmonary maternal immune activation does not extend through the placenta but leads to fetal metabolic adaptation University of Copenhagen University of Copenhagen 3
PR001942 Serum metabolites in inherited retinal degenerations National Taiwan University National Taiwan University 1
PR001941 The shutdown of NADH oxidation via Respiratory Complex I mimics fatty acid biosynthesis inhibition Wistar Institute Wistar Institute 5
PR001938 Role of central carbon metabolism in embryonic development Dept of Genetics, University of Cambridge Dept of Genetics, University of Cambridge 1
PR001936 Metabolomics of patients with Plasmodium vivax malaria University of Sao Paulo University of Sao Paulo 1
PR001935 Lipid unsaturation promotes BAX and BAK pore activity during apoptosis University of Cologne University of Cologne 1
PR001934 Glucose Hypometabolism Prompts RAN Translation and Exacerbates C9orf72-related ALS/FTD Phenotypes Thomas Jefferson University Thomas Jefferson University 2
PR001933 Inhibition of Asparagine Synthetase Effectively Retards Polycystic Kidney Disease Progression. San Raffaele University San Raffaele University 2
PR001931 Complete absence of GLUT1 does not impair human terminal erythroid differentiation University of Colorado University of Colorado 1
PR001930 Characterization of metabolic changes upon FGFR inhibition in ICC13-7 Xenograft mgh Massachusetts General Hospital 1
PR001929 13C-palmitate labeling experiment in ICC13-7 treated with DMSO or Infigratinib mgh Massachusetts General Hospital 1
PR001928 Activation of GFRAL+ Neurons Induces Hypothermia and Glucoregulatory Responses Associated with Nausea and Torpor University of Gothenburg University of Gothenburg 1
PR001927 The Human Cardiac “Age-OME”: Age-specific changes in myocardial molecular expression University of Sydney University of Sydney 2
PR001926 Reinforcing the Evidence of Mitochondrial Dysfunction in Long COVID Patients using a Multiplatform Mass Spectrometry-based Metabolomics Approach Universidad CEU San Pablo Universidad CEU San Pablo 1
PR001925 Cellular adaptation to cancer therapy occurs by progressive state transitions along a resistance continuum NYU Langone Health NYU Langone Health 1
PR001924 Parallel pheromonal, metabolite, and lipid analyses reveal patterns associated with early life transitions and ovary activation in honey bee (Apis mellifera) queens Life Sciences Institute, The University of British Columbia Life Sciences Institute, The University of British Columbia 1
PR001923 Lactiplantibacillus plantarum intervention on gestational health of gestational fecal microbiome transplant germ-free mice Beijing Sanyuan Foods Co. Ltd Beijing Sanyuan Foods Co. Ltd 7
PR001922 Integrative Analysis of Cytokine and Lipidomics Datasets Fol-lowing Mild Traumatic Brain Injury in the Rat Georgia Institute of Technology Georgia Institute of Technology 1
PR001921 Prediction of metabolites associated with somatic mutations in cancers by using genome-scale metabolic models and mutation data Korea Advanced Institute of Science and Technology (KAIST) Korea Advanced Institute of Science and Technology (KAIST) 1
PR001920 T cell Immune Escape in Blast Crisis Transformation of Chronic Myeloid Leukemia Translational Genomics Research Institute Translational Genomics Research Institute 1
PR001918 Metabolomics of Mouse Embryonic CSF Following Maternal Immune Activation Boston Childrens Hospital Boston Children's Hospital, Harvard Medical School 1
PR001917 Dynamic exometabolomics reveals metabolic adaptations of Staphylococcus epidermidis to pH-mimicking skin and bloodstream ITQB NOVA ITQB NOVA 1
PR001916 Data-dependent and -independent acquisition lipidomics analysis reveals the tissue-dependent effect of metformin on lipid metabolism North Carolina State University North Carolina State University 2
PR001915 Evaluation of a python-centric metabolomics data processing pipeline based on Asari. Jackson Laboratory for Genomic Medicine Jackson Laboratory for Genomic Medicine 2
PR001914 Optimized Mass Spectrometry Detection of Thyroid Hormones and Polar Metabolites in Rodent Cerebrospinal Fluid Boston Childrens Hospital Boston Childrens Hospital 3
PR001913 Attenuation of Helicobacter pylori VacA toxin-induced cell death by modulation of intracellular taurine metabolism Vanderbilt University Vanderbilt University 4
PR001912 Heritability of RBC metabolites: baseline correlation of metabolites and markers of RBC health and stability University of Iowa University of Iowa 1
PR001910 Metabolic responses of Amaranthus caudatus roots and leaves to zinc stress K.A. Timiryazev Institute of Plant Physiology RAS K.A. Timiryazev Institute of Plant Physiology RAS, Moscow, Russia 1
PR001909 Uncoupling Metabolic Health from Thermogenesis via BCAA Nitrogen Flux in Brown Fat - Serum metabolomics from control and MBC UCP1-KO BIDMC BIDMC 1
PR001907 Characterization of CsUGT73AC15 as a Multifunctional Glycosyltransferase Impacting Flavonol Triglycoside Biosynthesis in Tea Plants Fujian Agriculture and Forestry University Fujian Agriculture and Forestry University 1
PR001906 Investigation of metabolism in ER+ breast cancer University of Michigan Dartmouth College 1
PR001903 Integrated metabolomics and proteomics of symptomatic and early pre-symptomatic states of colitis University of Florence University of Florence 1
PR001902 Providing insight into the mechanism of action of Cationic Lipidated Oligomers (CLOs) using metabolomics Monash University Monash University 1
PR001900 Oxidative stress of breast cancer endocrine therapy persisters University of Michigan Dartmouth College 1
PR001899 Plasma instead of serum avoids critical confounding of clinical metabolomics studies by platelets University of Vienna University of Vienna 3
PR001898 Identification and validation of serum metabolite biomarkers for endometrial cancer diagnosis Shanghai Jiao Tong University Shanghai Jiao Tong University 1
PR001897 Defective mitochondria remodelling in B cells leads to an aged immune response Consejo Superior de Investigaciones Científicas Consejo Superior de Investigaciones Científicas 1
PR001896 Multi-Omics Plasma Signatures of Severe Injury with Influence of REBOA Intervention in a Swine Model. 1) Department of Biochemistry and Molecular Genetics, University of Colorado Denver – Anschutz Medical Campus, Aurora, CO, USA University of Colorado Anschutz Medical Campus 1
PR001895 Proteomic and metabolomic signatures of rectal tumor discriminate patients with different responses to preoperative radiotherapy Institute of Bioorganic Chemistry Polish Academy of Sciences Institute of Bioorganic Chemistry Polish Academy of Sciences 1
PR001894 Retinoid levels measurement in kidney and serum Weill Cornell Medicine Weill Cornell Medicine 1
PR001893 The metabolomic resetting effect of DY131 in cisplatin-induced AKI Children's Hospital of Nanjing Medical University Children's Hospital of Nanjing Medical University 1
PR001892 Lipid analysis of BMS309403-treated myeloma cells in vitro and in vivo Mainehealth Mainehealth 1
PR001891 A Non-Targeted Metabolomics Comparative Study on Plasma of Pfizer and Sinopharm COVID- 19 Vaccinated individuals, Assessed by (TIMS-QTOF) Mass Spectrometry. Sharjah Institute for Medical Research Sharjah Institute for Medical Research 1
PR001888 Central Transcriptional Regulator Controls Growth and Carbon Storage under High Light Stress in Photosynthetic Microalgae Model Strains National Renewable Energy Lab National Renewable Energy Lab 1
PR001887 Short chain fatty acid (SCFA) analysis in a bioreactor model system exposed to PFAS and bisphenols. Helmholtz Centre for Environmental Research Helmholtz Centre for Environmental Research 1
PR001884 Early time-restricted eating improves markers of cardiometabolic health but has no impact on nutrient absorption in healthy adults Pennington Biomedical Research Center California Polytechnic State University, San Luis Obispo 1
PR001883 A small molecule macrophage migration inhibitory factor agonist ameliorates age-related myocardial intolerance to ischemia-reperfusion insults via metabolic regulation University of Mississippi Medical Center University of Mississippi Medical Center 2
PR001882 Estrogen-mediated inhibition of purine metabolism and cell cycle arrest as a novel therapeutic approach in colorectal cancer cells Sharjah Institute for Medical Research Sharjah Institute for Medical Research 1
PR001881 Chronic stress dampens Lactobacillus johnsonii-mediated tumor suppression to enhance colorectal cancer progression China Pharmaceutical University China Pharmaceutical University 1
PR001880 Untargeted Metabolomics Reveals Unique Biomolecular Signatures in Overweight and Obesity Using UHPLC-ESI-QTOF-MS Analysis Sharjah Institute for Medical Research Sharjah Institute for Medical Research 1
PR001879 Identifying and mathematically modeling the time-course of extracellular metabolic markers associated with resistance to ceftolozane/tazobactam in Pseudomonas aeruginosa Monash Institute of Pharmaceutical Sciences Monash Institute of Pharmaceutical Sciences 2
PR001878 Lipidomics and plasma hormone reveal indicators of reproductive status in Florida manatees (Trichechus manatus latirostris) University of Florida University of Florida 1
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