Data for ST003224
| Metabolite structure | All data | F1 | F2 | F3 | F4 |
|---|---|---|---|---|---|
| 1_3-Bisphosphoglyceric acid | 2396548949.33 | 2897419008.00 | 1255277876.19 | 2604941738.67 | |
| 2-dehydro-D-gluconate | 11679947.00 | 18502547.67 | 6591535.99 | 18743964.33 | |
| 2-Hydroxy-2-methylbutanedioic acid | 139043445.33 | 177035194.67 | 78605249.67 | 145399365.33 | |
| 2-oxo-4-methylthiobutanoate | 188026.05 | 281796.99 | 190233.76 | 179640.16 | |
| 3-phosphoglycerate | 266645749.33 | 213599493.33 | 150384352.94 | 319811434.67 | |
| 3-phospho-serine | 93896994.67 | 102176712.00 | 45779063.39 | 104150213.33 | |
| 4-aminobutyrate | 179243098.67 | 153825893.33 | 84497482.08 | 180681514.67 | |
| 4-phosphopantothenate | 141802138.67 | 165284128.00 | 114289310.75 | 194879104.00 | |
| 4-Pyridoxic acid | 16710157.00 | 16721923.33 | 8583093.44 | 17954190.00 | |
| 6-phospho-D-gluconate | 85447306.67 | 81680266.67 | 41163146.84 | 92296805.33 | |
| acetyl-aspartate | 3979046.75 | 4071056.92 | 2131972.06 | 4391983.92 | |
| acetyl-CoA | 7951196.67 | 14389770.00 | 9767515.67 | 11475904.00 | |
| Acetyl-glycine | 3857064.42 | 4067235.58 | 3364028.21 | 4104605.17 | |
| Acetyllysine | 5977767.67 | 3126150.67 | 2118551.07 | 7992335.00 | |
| aconitate | 4144699.67 | 4237323.83 | 2387390.22 | 6110927.50 | |
| adenine | 24811752.00 | 23914519.33 | 15279091.62 | 25222952.00 | |
| ADP-D-glucose | 8151520.83 | 8365860.33 | 7747079.50 | 9062892.00 | |
| a-ketoglutarate | 104300666.67 | 78219592.00 | 49194490.17 | 132895789.33 | |
| alanine/sarcosine | 15768758.00 | 13088317.67 | 8624115.38 | 18491975.33 | |
| allantoin | 223529.34 | 256811.47 | 166141.00 | 270494.29 | |
| Aminoadipic acid | 375073.26 | 454656.68 | 242068.56 | 485179.34 | |
| anthranilate | 848764.77 | 534647.31 | 815761.58 | 912322.90 | |
| arginine | 51527996.61 | 30190332.52 | 27891305.58 | 38191324.48 | |
| Ascorbic acid | 3314959.50 | 7287247.50 | 3380903.30 | 5381569.67 | |
| asparagine | 198380800.00 | 187042533.33 | 100456523.08 | 219795322.67 | |
| aspartate | 1798051537.67 | 2071829594.33 | 1125274012.86 | 2838587192.33 | |
| aspartate (standard) | 337008096.00 | 333686816.00 | 335683658.67 | 321700448.00 | |
| Asp-Leu-His (DLH) | 63613341.33 | 27052206.00 | 22458028.87 | 81651090.67 | |
| Asp-Leu-Ser (DLS) | 14265841.33 | 6664112.17 | 6624953.52 | 18216448.67 | |
| Benzoyl-CoA | 60706.60 | 33752.79 | 45926.16 | 47213.55 | |
| Carbamoyl phosphate | 27760.18 | 94850.95 | 67769.50 | 47347.24 | |
| carnitine | 2949471.09 | 2335020.92 | 1642900.19 | 2984349.27 | |
| cCMP | 132958.95 | 181720.69 | 177992.46 | 136314.18 | |
| CDP | 12447796.00 | 24567397.83 | 20867798.83 | 18151474.50 | |
| CDP-choline | 3887756.83 | 6068531.33 | 4348113.83 | 7278297.17 | |
| CDP-ethanolamine | 263324949.33 | 370128789.33 | 170977837.06 | 332637152.00 | |
| cGMP | 1057612.54 | 1189339.37 | 654528.49 | 1257246.38 | |
| chlorpropamide | 395048113.87 | 388212736.00 | 375988826.67 | 387368320.00 | |
| Citraconic acid | 17603974.67 | 22729682.67 | 9639909.50 | 19330740.67 | |
| citrate/isocitrate | 69673249.50 | 90037246.00 | 48367326.53 | 109783090.33 | |
| CMP | 20527798.67 | 34820048.67 | 26261458.00 | 28315742.67 | |
| coenzyme A | 1821638.37 | 1768743.83 | 1203476.08 | 2639310.50 | |
| creatine | 1253805.21 | 1880554.62 | 897377.45 | 1880767.67 | |
| CTP | 64930661.33 | 140125250.67 | 109723674.37 | 131984186.67 | |
| cystathionine | 878171.13 | 578240.40 | 454053.87 | 927935.79 | |
| Cystine | 229495.72 | 566420.69 | 818072.74 | 225845.43 | |
| cytidine | 1225461930.67 | 968705962.67 | 576066120.33 | 1153127936.00 | |
| dAMP | 828368.50 | 769991.71 | 399510.68 | 589072.79 | |
| dATP | 39728709.33 | 30196471.33 | 19467413.59 | 35725538.67 | |
| dCDP | 1877919.96 | 2833778.33 | 2024203.75 | 1898003.17 | |
| dCMP | 4736623.83 | 6705468.17 | 3604245.49 | 5271930.83 | |
| dCTP | 12668956.67 | 18833215.33 | 17239131.00 | 18836802.67 | |
| Decanoyl-CoA | 2690150.63 | 5113375.67 | 1725197.93 | 3058944.92 | |
| deoxyadenosine | 7682840.50 | 8731666.33 | 3719019.27 | 9047309.33 | |
| deoxyguanosine (1) | 1378471.87 | 1111487.06 | 840041.67 | 1487183.42 | |
| deoxyinosine | 642577.04 | 376860.90 | 283586.55 | 475791.54 | |
| deoxyribose-phosphate | 9532867.00 | 26377019.33 | 7836090.76 | 13747415.00 | |
| deoxyuridine | 31078784.67 | 27537712.00 | 14851150.12 | 25018076.00 | |
| D-erythrose-4-phosphate | 926938.17 | 1160270.29 | 574922.94 | 1240129.50 | |
| dGDP/ADP | 455023344.00 | 417069762.67 | 183755973.72 | 426935608.00 | |
| D-gluconate | 254230186.67 | 237013434.67 | 116953590.99 | 266741189.33 | |
| D-glucosamine-1/6-phosphate | 980710.29 | 1032054.15 | 404512.79 | 1052214.38 | |
| dGMP/AMP | 107028816.00 | 96210458.67 | 42358541.28 | 90660794.67 | |
| dGTP/ATP | 3746549418.67 | 3339127466.67 | 2013026281.35 | 3937412352.00 | |
| dihydroorotate | 747486656.00 | 37131886.67 | 106249356.48 | 59091474.67 | |
| dihydroxy-acetone-phosphate | 40663809.33 | 39740002.67 | 27583596.55 | 51738394.67 | |
| DL-Pipecolic Acid | 97493141.33 | 21334952.67 | 24905437.52 | 82843664.00 | |
| D-sedoheptulose-1/7-phosphate | 38572521.33 | 40182392.00 | 20992155.60 | 36196853.33 | |
| dTDP | 4507356.92 | 10644098.58 | 5558417.90 | 9466234.00 | |
| dTMP | 2143928.00 | 3095111.00 | 1397340.97 | 2509801.58 | |
| dTTP | 52681873.33 | 111570357.33 | 51358050.81 | 124312386.67 | |
| dUMP | 669773.46 | 636705.42 | 350156.92 | 729715.25 | |
| FAD | 9916875.33 | 10199805.67 | 6586043.21 | 9984775.67 | |
| FMN | 258715.02 | 312624.80 | 282672.38 | 400287.74 | |
| folate | 11129654.67 | 11901731.00 | 10351482.67 | 12059447.33 | |
| fructose-1-6-bisphosphate | 248624362.67 | 258285968.00 | 230068450.25 | 312105013.33 | |
| fumarate | 32301487.33 | 19071788.67 | 14430376.70 | 42410070.67 | |
| GDP | 42122583.33 | 39120311.67 | 20467670.03 | 34917704.67 | |
| glucono-lactone | 47990710.67 | 55728968.00 | 26821534.77 | 60106961.33 | |
| glucose-1-phosphate | 71891372.00 | 67178919.33 | 33009448.11 | 77966016.67 | |
| glutamate | 12868225024.00 | 10363860309.33 | 5359138068.33 | 12538920960.00 | |
| glutamine | 768895082.67 | 670989845.33 | 362723436.50 | 761873450.67 | |
| glutathione | 1718928256.00 | 1656073642.67 | 678664047.75 | 2059489237.33 | |
| glutathione disulfide | 867642666.67 | 778196736.00 | 390364745.28 | 902370880.00 | |
| glycerate | 3187601.25 | 3025455.92 | 1722437.47 | 3100974.42 | |
| GMP | 77358394.67 | 50752668.00 | 23080230.60 | 63153958.67 | |
| GTP | 205020373.33 | 179699456.00 | 112007243.96 | 196698437.33 | |
| Guanidoacetic acid | 232336.58 | 195194.68 | 204564.61 | 240219.10 | |
| guanine | 47031792.33 | 39132602.00 | 16320819.57 | 32401430.33 | |
| guanosine | 4717521.33 | 4245688.92 | 1506366.94 | 2926840.25 | |
| Hexose | 490172736.00 | 455516810.67 | 243271911.17 | 487704757.33 | |
| hexose-phosphate | 319694045.33 | 371266981.33 | 188447776.01 | 425498113.33 | |
| histidine | 30702048.67 | 23163561.33 | 15256953.67 | 34373779.33 | |
| His-Val-Asp-Asp (HVDD) | 6757488.83 | 2355358.33 | 4473657.83 | 9166273.33 | |
| homocysteine | 120071.84 | 114824.13 | 75849.25 | 107393.53 | |
| Hydroxyphenylacetic acid | 2253476.08 | 2841194.33 | 2512538.62 | 2061384.17 | |
| hydroxyproline/Aminolevulinate | 59479089.33 | 56284700.00 | 28649268.31 | 61999237.33 | |
| hypoxanthine | 713437802.67 | 646134058.67 | 320750133.58 | 701089066.67 | |
| IDP | 225493.48 | 336953.78 | 118805.44 | 309159.77 | |
| IMP | 288770005.33 | 314244800.00 | 121308959.45 | 289501664.00 | |
| indole | 599271.39 | 558321.64 | 645803.06 | 618103.41 | |
| Indoleacrylic acid | 1171955.96 | 1515516.42 | 1372975.91 | 1418736.04 | |
| inosine | 57177318.33 | 53211952.67 | 26760765.37 | 61896851.33 | |
| isoleucine | 1577722282.67 | 1351212458.67 | 714521783.67 | 1473998208.00 | |
| Kynurenine | 126834.49 | 100813.48 | 67962.44 | 117825.55 | |
| lactate | 3931824469.33 | 3239024469.33 | 2918121280.00 | 4351358208.00 | |
| L-arginino-succinate | 4572601.33 | 3213977.42 | 3165951.25 | 5313733.33 | |
| Leu-Asp (LD) | 16159899.00 | 12680665.67 | 7166678.79 | 19133834.67 | |
| leucine | 2043657301.33 | 1657631146.67 | 914040938.67 | 1954083754.67 | |
| lysine | 45814229.33 | 11633127.00 | 19363234.79 | 39253692.00 | |
| malate | 2368581546.67 | 1496887253.33 | 992469534.00 | 2754281984.00 | |
| maleic acid | 183464762.67 | 91351944.00 | 67009053.91 | 167386763.33 | |
| mefloquine | 838845.29 | 890155.02 | 754850.41 | 889120.81 | |
| methionine | 306633888.00 | 242186890.67 | 135336817.76 | 288151018.67 | |
| myo-inositol | 56842818.67 | 62489708.67 | 37780375.04 | 71949778.67 | |
| N-acetyl-glucosamine | 428836.67 | 297907.36 | 131836.79 | 319029.59 | |
| N-acetyl-glucosamine-1/6-phosphate | 13848429.50 | 11416969.17 | 12438919.17 | 15605395.33 | |
| N-acetyl-glutamate | 22057738.00 | 20333047.33 | 9577271.17 | 23119450.67 | |
| N-acetyl-glutamine | 3167980.67 | 1485075.79 | 1030756.34 | 2647771.50 | |
| N-Acetyl-L-alanine | 54063274.67 | 35951254.67 | 19820392.89 | 47141204.00 | |
| N-acetyl-L-ornithine | 8327713.33 | 4407495.00 | 3263454.02 | 11231974.00 | |
| NAD+ | 603949077.33 | 616914880.00 | 366812858.69 | 776600768.00 | |
| NADH | 2264467.17 | 3508649.29 | 1866888.92 | 2202209.27 | |
| NADP+ | 170997856.00 | 180214608.00 | 120221681.72 | 196242837.33 | |
| NADPH | 31100114.67 | 42967650.00 | 27666645.49 | 35817683.33 | |
| N-carbamoyl-L-aspartate | 6012794197.33 | 451501130.67 | 1049918111.54 | 721497301.33 | |
| nicotinamide mononucleotide | 7265464.00 | 8336103.50 | 3592237.49 | 8521073.67 | |
| nicotinate | 14842933.67 | 15883502.67 | 6928369.72 | 14481833.33 | |
| Nicotinic acid mononucleotide | 54648486.67 | 64140073.33 | 27819937.76 | 72510974.67 | |
| Octulose 8/1P | 14766003.00 | 16351109.00 | 8183870.92 | 17647187.67 | |
| Octulose Bisphosphate | 6735992.83 | 4991320.33 | 8958717.83 | 7210906.83 | |
| ornithine | 12804010.67 | 10794539.50 | 5871079.24 | 12120856.33 | |
| orotate | 16673690.00 | 23236422.00 | 10103684.85 | 28447232.67 | |
| orotidine-5^-phosphate | 1033313.08 | 1012202.65 | 835823.08 | 1486822.88 | |
| oxaloacetate | 368867.98 | 421910.53 | 228964.74 | 511831.62 | |
| p-aminobenzoate | 2084492.87 | 1919289.46 | 1040970.84 | 1802368.96 | |
| pantothenate | 36404982.67 | 31460577.33 | 21622718.17 | 37364320.00 | |
| Phenol Red | 202057674.67 | 179321034.67 | 93963621.43 | 200434896.00 | |
| phenylalanine | 788823424.00 | 625832448.00 | 338830528.00 | 766213909.33 | |
| phosphoenolpyruvate | 28243118.00 | 23432801.33 | 18313935.49 | 33623086.67 | |
| p-hydroxybenzoate | 15444072.67 | 15958458.33 | 8335785.00 | 18740315.00 | |
| prephenate | 1799374.16 | 1187987.00 | 1194548.75 | 2225284.50 | |
| Pro-Asp (PD) | 663521621.33 | 157566645.33 | 192606713.57 | 712318378.67 | |
| Pro-Glu-Glu-Lys (PEEK) | 7631808.67 | 6549234.33 | 5585607.74 | 10443049.33 | |
| Pro-Glu-Glu (PEE) | 16225562.00 | 5687476.17 | 6096283.79 | 18838058.67 | |
| Pro-Glu (PE) | 72641864.00 | 21029021.33 | 27480754.80 | 74532762.67 | |
| proline | 141557594.67 | 118531101.33 | 67553391.33 | 139908128.00 | |
| propionyl-CoA | 20404.84 | 11516.24 | 23939.29 | 24002.40 | |
| Pro-Val-Asn-Phe (PVNF) | 13273418.67 | 4286366.92 | 8140159.67 | 15613940.00 | |
| pyridoxine | 79502933.33 | 71395238.67 | 36161139.77 | 70943293.33 | |
| Pyroglutamic acid | 428292234.67 | 467298357.33 | 345876600.00 | 471486400.00 | |
| Pyrophosphate | 1585342634.67 | 1227153898.67 | 544129852.14 | 1240018901.33 | |
| pyruvate | 176099760.00 | 192547600.00 | 136894250.00 | 204827029.33 | |
| quinolinate | 495173.43 | 597769.62 | 318177.44 | 512921.30 | |
| riboflavin | 670090.91 | 507297.52 | 543101.64 | 627863.79 | |
| ribose | 27241231.67 | 23597293.67 | 13074135.50 | 25779802.33 | |
| Ribose-5-phosphate | 112766536.00 | 82568114.67 | 58244521.54 | 129299720.00 | |
| Ribose-5-S-homocysteine | 218226.57 | 323335.28 | 265220.93 | 589826.21 | |
| ribose-phosphate | 33850498.00 | 25856470.00 | 16747914.13 | 39338165.33 | |
| ribulose-5-phosphate | 14231991.67 | 10502262.00 | 5287794.74 | 11950422.33 | |
| S-adenosyl-L-homocysteine | 52242950.67 | 51663634.67 | 22856381.14 | 54943166.67 | |
| S-adenosyl-L-methionine | 655119.38 | 547486.16 | 573264.09 | 649851.08 | |
| Sedoheptulose bisphosphate | 24699818.67 | 24428251.33 | 40683520.00 | 27704714.67 | |
| Ser-Asp-Leu (SDL) | 3842302.83 | 1429473.62 | 2337726.83 | 4623063.00 | |
| Ser-Asp (SD) | 25552622.33 | 14493311.17 | 11051662.73 | 29289306.50 | |
| Ser-Ile-Asp (SID) | 225580.77 | 285638.44 | 122063.08 | 228129.44 | |
| serine | 58513920.00 | 53296693.33 | 40672049.00 | 61422281.33 | |
| shikimate-3-phosphate | 22834550.67 | 21843341.33 | 14848631.05 | 35727120.00 | |
| S-methyl-5^-thioadenosine | 3873971.00 | 3842360.50 | 2853737.33 | 3649644.42 | |
| sn-glycerol-3-phosphate | 831085994.67 | 637104960.00 | 413635281.12 | 995494400.00 | |
| succinate/Methylmalonic acid | 704167488.00 | 921640021.33 | 412695748.00 | 662127936.00 | |
| succinyl-CoA/methylmalonyl-CoA | 86989.32 | 193109.78 | 126193.80 | 173175.16 | |
| taurine | 1162423.54 | 1417420.37 | 1212003.70 | 1529371.50 | |
| Tetrahydrobiopterin | 653587.42 | 471664.08 | 338435.96 | 633438.75 | |
| thiamine | 23225645.33 | 18699949.33 | 19197857.33 | 26251859.33 | |
| thiamine-phosphate | 294078.11 | 313061.99 | 259679.24 | 308270.80 | |
| Thiamine pyrophosphate | 9905821.59 | 9896566.40 | 6543939.93 | 12863623.75 | |
| threonine/homoserine | 50903004.00 | 40546860.00 | 26835612.75 | 52006384.00 | |
| thymidine | 562101.31 | 953123.25 | 472872.68 | 894982.21 | |
| trehalose-6-Phosphate | 218379.90 | 233644.30 | 170918.97 | 280916.70 | |
| tryptophan | 87621146.67 | 81805762.67 | 45781811.60 | 90181322.67 | |
| tyrosine | 712518293.33 | 627578240.00 | 322759959.33 | 688625301.33 | |
| UDP | 44507946.33 | 125506292.00 | 48124664.98 | 104491864.00 | |
| UDP-D-glucose | 221294858.67 | 246924928.00 | 117759477.02 | 245622202.67 | |
| UDP-D-glucuronate | 7838668.00 | 8427883.67 | 7780981.50 | 8952157.33 | |
| UDP-N-acetyl-glucosamine | 102214957.33 | 140368912.00 | 83118063.32 | 130105981.33 | |
| UMP | 135504861.33 | 261051125.33 | 99790900.37 | 278127354.67 | |
| uridine | 642220.42 | 2698496.42 | 490415.87 | 898485.73 | |
| UTP | 309727029.33 | 796111637.33 | 438145268.12 | 852189568.00 | |
| Val-Asp (VD) | 27339713.33 | 10856179.17 | 14945768.58 | 36607573.33 | |
| valine | 619921770.67 | 472816032.00 | 271830316.50 | 616201877.33 | |
| xanthine | 386443.15 | 355547.05 | 326203.70 | 412483.17 | |
| xanthosine | 5292236.17 | 1795777.92 | 2704669.33 | 3762268.00 | |
| xanthosine-5-phosphate | 5201774.67 | 5491202.00 | 3802240.29 | 6489630.17 | |
| Xanthurenic acid | 1457432.21 | 1485739.96 | 1026130.51 | 1518841.75 |
Factors:
| F1 | Treatment:ATQ |
| F2 | Treatment:AZD0156 |
| F3 | Treatment:N/A |
| F4 | Treatment:ND |
