Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST003347)

(Analysis AN005482)

Metabolite	Structure	F1	F2	F3	F4	F5	F6
asparagine	ME875120	0.45	0.41	0.54	0.26	0.74	2.29
N-acetylaspartate	ME875201	0.47	0.36	1.91	1.37	2.00	0.45
lanthionine	ME875192	1.03	0.56	0.57	0.78	2.50	0.78
thiamine	ME875239	1.10	0.45	0.99	1.06	2.30	0.55
isoleucine	ME875186	0.53	0.37	2.29	0.64	0.50	1.34
phenylalanine	ME875220	0.52	0.36	2.21	0.63	0.54	1.37
leucine	ME875193	0.53	0.34	2.57	0.63	0.50	1.21
N-acetylserine	ME875206	0.49	0.32	2.51	0.80	0.43	1.22
dimethyllysine	ME875149	0.53	1.18	2.87	0.60	0.55	0.64
homoarginine	ME875177	0.70	0.61	2.65	0.69	0.81	0.77
glyceraldehyde 3-phosphate	ME875164	0.71	0.92	2.36	0.51	0.75	0.88
hydroxytrimethyllysine	ME875181	0.85	0.93	2.33	0.78	0.63	0.74
tryptophan	ME875242	0.64	0.43	1.43	0.65	0.66	1.59
adenosine	ME875113	0.46	0.48	1.64	0.73	0.39	1.65
glycerol 3-phosphate	ME875165	0.51	0.33	1.71	0.42	0.42	1.80
xanthine	ME875251	0.27	1.01	1.47	1.16	1.07	1.02
NADP	ME875208	0.71	1.15	1.44	0.88	0.52	1.15
UTP	ME875249	0.72	1.01	1.52	0.94	0.59	1.11
cAMP	ME875128	0.30	2.18	0.75	1.10	2.04	0.32
glycerophosphoinositol	ME875167	0.88	1.78	1.56	0.44	1.70	0.32
myo-inositol	ME875199	0.77	1.44	1.34	0.96	1.61	0.44
propionylcarnitine	ME875224	0.52	0.69	0.64	0.76	2.04	1.18
taurine	ME875238	0.46	0.28	1.19	0.59	1.65	1.41
2-ketoglutarate	ME875109	0.67	0.93	0.52	0.39	1.27	1.61
2/3-phosphoglycerate	ME875106	1.25	0.87	1.07	0.62	1.23	0.97
dTTP	ME875150	0.99	0.68	1.10	0.36	1.17	1.39
glucose 6-phosphate	ME875158	0.78	0.78	1.55	0.70	1.14	1.02
S-(2-succinyl)cysteine	ME875229	0.79	0.83	1.29	0.46	1.34	1.14
oxidized glutathione	ME875218	0.79	1.50	0.97	0.54	0.70	1.25
betaine	ME875126	0.43	1.14	1.21	0.32	1.34	1.28
AMP	ME875117	0.61	1.41	1.32	0.28	0.98	1.20
fructose 6-Phosphate	ME875151	0.42	1.30	1.11	0.38	0.90	1.45
NADPH	ME875209	0.33	1.11	1.21	0.45	1.88	1.01
uridine	ME875248	0.38	1.27	1.25	0.45	1.69	0.98
IMP	ME875184	0.52	1.15	0.96	0.78	1.09	1.27
ADP-ribose	ME875115	0.20	1.06	0.99	0.85	1.44	1.22
carnitinamide	ME875129	0.53	1.11	0.89	0.87	1.39	1.10
methyllysine	ME875198	0.51	1.37	0.90	0.89	1.43	0.95
gluconate	ME875156	0.90	1.43	0.66	0.23	1.60	1.08
kynurenine	ME875190	0.62	1.56	0.79	0.30	1.68	1.02
guanidinobutyrate	ME875173	0.57	1.55	0.91	0.58	1.40	1.00
isovalerylcarnitine C5	ME875187	0.79	1.31	0.92	0.49	1.24	1.12
lactate	ME875191	1.02	1.21	2.14	0.28	0.44	0.96
citrulline	ME875137	0.99	1.47	1.42	0.25	0.33	1.28
cystathionine	ME875143	1.34	1.41	1.56	0.60	0.58	0.76
argininosuccinate	ME875119	0.21	2.04	1.26	0.52	1.20	0.88
GDP-glucose	ME875155	0.66	2.35	1.32	0.40	0.98	0.65
homocitrulline	ME875178	0.33	2.25	0.80	0.87	0.38	1.18
ATP	ME875123	0.34	1.31	1.19	0.70	0.39	1.54
UDP-glucose	ME875245	0.24	1.53	1.49	0.37	0.55	1.41
aspartate	ME875121	0.37	1.58	1.36	0.42	0.28	1.50
GMP	ME875171	0.59	1.61	1.20	0.44	0.37	1.40
beta-citrylglutamic acid	ME875125	0.32	1.92	1.26	0.30	0.27	1.47
carnosine	ME875131	0.33	2.10	1.39	0.34	0.28	1.28
inosine	ME875185	0.43	2.08	1.42	0.31	0.70	1.03
UMP	ME875246	0.40	1.93	1.51	0.58	0.40	1.09
dihydroorotate	ME875146	1.68	2.00	0.71	1.35	0.40	0.43
propionylcholine	ME875225	0.46	0.70	0.62	2.36	1.39	0.74
pantothenate	ME875219	0.46	1.17	1.13	1.72	0.36	1.08
3-phosphoserine	ME875110	0.64	1.48	0.61	1.60	0.57	1.05
cytidine	ME875144	0.28	1.19	0.42	1.77	0.94	1.20
cytosine	ME875145	0.26	1.29	0.53	1.70	0.83	1.20
glycerylphosphorylcholine	ME875168	0.36	1.52	0.40	2.06	1.25	0.70
beta-alanine	ME875124	1.02	1.14	0.58	2.02	0.66	0.79
hypotaurine	ME875182	0.83	1.35	0.69	2.12	0.74	0.63
citrate	ME875136	1.23	0.40	0.42	2.22	0.69	1.02
ophthalmic acid	ME875214	1.61	0.56	0.52	2.28	0.53	0.75
phosphocreatine	ME875222	0.75	0.54	0.41	1.32	0.71	1.63
alanine	ME875116	0.70	0.68	0.56	1.14	1.18	1.37
ketoleucine+ketoisoleucine	ME875188	0.56	0.83	0.44	1.36	1.45	1.18
N-acetylaspartylglutamate	ME875202	0.79	1.21	0.87	1.02	0.86	1.12
sarcosine	ME875233	1.00	1.01	1.01	1.13	1.01	0.92
glucose	ME875157	1.18	1.10	0.94	0.97	0.90	0.96
malate	ME875195	1.18	0.94	0.87	1.04	0.95	1.01
sedoheptulose 7-phosphate	ME875234	0.76	1.30	0.74	1.34	1.14	0.83
uric acid	ME875247	0.96	1.52	0.96	1.18	0.84	0.77
hypoxanthine	ME875183	1.21	1.02	1.19	1.42	0.93	0.61
S-(2-Succinyl)glutathione	ME875230	1.26	0.66	1.36	1.67	0.96	0.54
orotate	ME875216	1.02	0.44	1.02	1.47	1.02	1.02
histidine	ME875176	0.87	0.67	1.42	1.01	0.87	1.08
pyroglutamic acid	ME875227	1.05	0.90	1.18	1.27	0.47	1.06
CDP	ME875132	1.14	0.67	1.21	1.25	0.92	0.91
succinate	ME875236	1.16	0.72	1.03	1.23	0.92	0.97
ketovaline	ME875189	1.01	0.86	1.20	1.36	0.70	0.94
UDP-GlcNac	ME875244	0.93	0.80	1.36	1.29	0.87	0.88
acetylcarnitine	ME875111	1.63	0.59	0.96	1.41	1.28	0.56
glycerophosphoethanolamine	ME875166	1.51	0.74	0.94	1.39	0.75	0.83
hydroxyphenyllactate	ME875179	1.41	0.70	0.71	1.81	0.79	0.79
cyclic ADP-ribose	ME875141	1.47	0.61	0.77	1.54	0.89	0.86
nicotinamide riboside	ME875212	1.50	0.81	0.68	1.58	0.80	0.81
2-aminoadipic acid	ME875107	1.69	0.86	0.61	1.35	0.91	0.79
valine-d8	ME875105	1.86	0.58	0.59	1.53	0.93	0.76
acetylcholine	ME875112	1.77	0.65	0.49	1.70	0.79	0.80
Cys-Gly	ME875142	1.67	0.77	0.44	1.60	0.77	0.88
lysine	ME875194	1.02	0.87	0.51	1.68	1.21	0.85
noradrenaline	ME875213	1.12	0.78	0.58	1.93	1.07	0.76
pyridoxine	ME875226	1.29	0.80	0.59	1.77	0.99	0.78
CMP-acetylneuraminic acid	ME875138	1.26	0.70	0.57	1.67	1.32	0.74
aspartylglucosamine	ME875122	1.45	0.83	0.52	1.48	1.38	0.67
phosphocholine	ME875221	1.47	0.86	0.41	1.67	1.29	0.65
N-acetylneuramic acid	ME875204	1.30	1.06	0.61	1.73	1.12	0.59
serine	ME875235	1.51	0.89	0.57	1.66	1.00	0.69
orotidine	ME875217	0.78	0.88	0.63	1.49	0.89	1.16
trimethyllysine	ME875241	0.94	0.97	0.72	1.21	0.91	1.12
glycine	ME875169	1.04	0.72	0.61	1.37	0.82	1.22
NAD	ME875207	1.17	0.77	0.62	1.23	0.89	1.16
fumarate	ME875152	1.14	0.90	0.71	1.55	0.75	0.98
ornithine	ME875215	1.26	0.68	0.55	1.43	1.01	1.03
guanosine	ME875175	1.10	0.86	0.58	1.59	1.00	0.94
N-acetylglutamate	ME875203	1.11	0.86	0.51	1.57	0.93	1.01
creatinine	ME875140	1.27	0.77	0.62	1.60	0.82	0.96
glutathione	ME875163	1.38	0.81	0.51	1.61	0.95	0.88
N-acetylarginine	ME875200	1.38	0.94	0.80	1.36	1.02	0.75
N-acetylornithine	ME875205	1.36	0.96	0.78	1.47	1.12	0.66
N-carbamoylglutamate	ME875211	1.29	1.04	0.70	1.35	0.95	0.84
proline	ME875223	1.32	1.01	0.60	1.51	1.01	0.77
GABA	ME875153	1.16	0.75	0.73	1.35	1.22	0.89
2-hydroxyglutarate	ME875108	1.11	0.95	0.70	1.28	1.10	0.93
glutamine	ME875161	1.19	0.90	0.73	1.26	1.15	0.88
arginine	ME875118	1.08	0.86	0.67	1.29	1.04	1.03
glutamylproline	ME875162	1.10	0.80	0.63	1.37	1.10	1.00
glutamate	ME875160	1.09	0.86	0.69	1.53	1.16	0.84
creatine	ME875139	1.12	0.90	0.76	1.42	0.98	0.91
GDP	ME875154	1.09	0.82	0.83	1.58	0.98	0.85
methionine sulfoxide	ME875196	1.39	0.74	0.56	1.24	1.55	0.76
hydroxyproline	ME875180	1.15	1.07	0.66	0.91	1.36	0.92
methionine	ME875197	1.09	0.96	0.57	1.24	1.38	0.88
S-adenosylhomocysteine	ME875231	1.27	1.10	0.67	1.15	1.21	0.80
dimethylarginine	ME875148	1.35	0.92	0.46	1.21	0.95	1.06
threonine	ME875240	1.43	0.97	0.43	1.17	1.11	0.95
GTP	ME875172	1.44	0.75	0.85	1.26	1.13	0.78
glycylglycine	ME875170	1.36	0.72	0.64	1.27	1.23	0.89
citicoline	ME875135	1.42	0.80	0.63	1.15	1.17	0.92
valine	ME875250	1.51	0.86	0.68	1.08	1.16	0.86
carnitine	ME875130	1.70	0.36	1.28	0.92	0.65	1.05
pyruvate	ME875228	1.35	0.60	1.19	0.58	0.56	1.36
cis-aconitate	ME875134	1.66	1.03	1.31	0.29	0.95	0.88
dihydroxyacetone phosphate	ME875147	1.38	1.10	0.94	0.35	0.83	1.20
succinyladenosine	ME875237	2.03	1.19	0.75	0.47	0.80	0.85
glucuronic acid	ME875159	1.65	1.26	0.85	0.29	1.35	0.80
tyrosine	ME875243	1.57	1.19	0.70	0.60	1.14	0.90
S-adenosylmethionine	ME875232	1.31	0.69	0.50	0.57	1.64	1.14
ADP	ME875114	1.61	0.76	0.55	0.81	1.49	0.89
butyrylcarnitine	ME875127	1.64	0.87	0.68	0.67	1.64	0.75
N-carbamoylaspartate	ME875210	1.49	0.47	0.75	0.72	1.08	1.24
choline	ME875133	1.95	0.85	0.41	1.08	1.00	0.86
guanine	ME875174	1.63	0.93	0.52	0.82	0.89	1.10

Factors:

F1	Genotype:A3V/R337X \| Sex:F
F2	Genotype:M26L/R396H \| Sex:F
F3	Genotype:M26L/R396H \| Sex:M
F4	Genotype:R309H/c.1191+5G->C \| Sex:F
F5	Genotype:Wildtype \| Sex:F
F6	Genotype:Wildtype \| Sex:M

Data matrix