Clustering data with hclust algorithm for (Study ST003629)
(Analysis AN005961)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| LPI(20:4)-H | ME938937 | NA | NA | 154685063.13 | 386672971.06 | NA | 41626570.33 | NA | NA | 189601299.56 | NA | NA | 768920.29 | 193270709.13 | 139935401.34 |
| PC(12:0e_18:1)+HCOO | ME938941 | NA | NA | 5479823646.00 | NA | 2632010018.00 | NA | NA | NA | 21320225542.00 | 9340935241.00 | NA | 1567106915.00 | 21587867554.00 | 17352391661.00 |
| LPC(18:1)+HCOO | ME938914 | 63736739.91 | 51215329.74 | 25655794.83 | 28868931.39 | 41204755.26 | 42740366.51 | NA | NA | 23628935.83 | 39236118.43 | 43824751.80 | 20222938.01 | NA | 20185457.45 |
| LPE(20:5)-H | ME938930 | 282961422.02 | 287268043.59 | NA | 281724140.50 | 280301875.21 | 281783827.45 | NA | NA | NA | 282869913.40 | 282100111.21 | NA | NA | NA |
| dMePE(18:1_18:2)-H | ME938903 | 22155828.19 | NA | NA | NA | 106960168.23 | NA | NA | NA | 45020126.38 | NA | 38537657.04 | 718262.92 | 46783598.58 | 33789688.62 |
| dMePE(14:1e_20:5)-H | ME938884 | -115937034.22 | -108802719.85 | NA | NA | NA | -107021720.30 | NA | NA | NA | -107678190.95 | -106388066.22 | -100794837.83 | NA | -97022352.62 |
| dMePE(18:0_16:0)-H | ME938899 | NA | NA | 9846240.28 | NA | 247447384.69 | NA | NA | NA | 130840113.08 | NA | 37646549.79 | 72861546.73 | 162669270.09 | 91285257.42 |
| dMePE(16:0_18:2)-H | ME938888 | 37863214.83 | NA | 88063079.83 | 41500495.17 | NA | NA | NA | NA | 380208154.67 | NA | NA | 38990134.33 | 208106060.83 | 267888466.50 |
| Hex1Cer(t16:0_22:5)-H | ME938909 | NA | NA | 22633684.86 | 217541888.93 | NA | NA | NA | NA | 1433077527.36 | 833605007.71 | 341582557.64 | 419712395.14 | 1775382518.64 | 1156658117.21 |
| PC(12:0e_16:0)+HCOO | ME938940 | 467919057.90 | 467327072.79 | NA | 465467216.69 | NA | NA | NA | NA | NA | 470421451.69 | 467920866.45 | 464474945.00 | NA | 471414062.48 |
| dMePE(14:1e_20:4)-H | ME938883 | NA | NA | -1467566554.14 | NA | -1476306242.71 | NA | NA | NA | -1209798591.57 | -209851950.79 | -1436174963.14 | NA | -1196207459.86 | -668193042.00 |
| dMePE(16:0_16:0)-H | ME938886 | -102779748.62 | -99547756.61 | NA | -100768779.34 | -100915193.62 | NA | NA | NA | -99339489.09 | NA | -100240889.22 | -101259818.37 | NA | -99206719.82 |
| Cer(d20:1_24:0)+HCOO | ME938880 | 25270196.66 | NA | NA | 95187058.54 | NA | NA | NA | NA | 307415912.70 | NA | 48538027.69 | 92882724.31 | 302621782.70 | 217123614.96 |
| LPE(20:1)-H | ME938927 | NA | 454725198.52 | NA | 23182219.42 | NA | 453182442.49 | NA | NA | 155443651.60 | NA | NA | 38465884.18 | 163627987.03 | 166726299.92 |
| LPI(18:0)-H | ME938936 | 343460496.31 | 335439011.83 | 340633418.93 | 359970062.14 | 343535986.28 | 355228528.83 | NA | NA | NA | 353266051.83 | 361589463.93 | 340647142.38 | NA | 330231570.86 |
| Cer(d18:1_16:0)+HCOO | ME938871 | INF | INF | NA | INF | INF | INF | NA | NA | NA | INF | INF | INF | NA | NA |
| LBPA(18:1_20:3)-H | ME938911 | -570032239.33 | -583986849.93 | -555107847.15 | -558235886.19 | -556345352.44 | -556630196.22 | NA | NA | NA | -556827693.07 | -557787857.81 | NA | NA | NA |
| LPE(20:3)-H | ME938928 | -71861174.55 | -71424572.45 | -65920834.34 | -73375380.82 | -68214569.96 | -68907176.63 | NA | NA | NA | -70038370.32 | -69235617.97 | -64631972.85 | NA | NA |
| dMePE(14:1e_22:6)-H | ME938885 | NA | NA | -84902144.97 | -83242161.29 | -91409813.79 | -92066510.77 | NA | NA | -12371318.47 | -83871496.57 | NA | -80993890.80 | -36463007.89 | NA |
| LPE(18:1)-H | ME938923 | 71745909.85 | 74173348.77 | 70086512.49 | 72921325.60 | 73333767.12 | 72994013.91 | NA | NA | NA | 73478325.27 | 72377394.49 | 70682710.50 | NA | NA |
| Cer(d18:1_24:0)-H | ME938876 | 3790730058.50 | NA | NA | NA | NA | 527952672.50 | NA | NA | 3905384749.75 | NA | 367833169.00 | 254314560.50 | 6893881112.25 | 3016738452.75 |
| Hex1Cer(d18:1_24:0)+HCOO | ME938907 | -44812249.39 | NA | -27220861.65 | NA | -578109.08 | -28321616.94 | NA | NA | -218251441.24 | NA | NA | NA | -235417455.02 | -198234995.47 |
| LPE(18:2)-H | ME938926 | -214131999.30 | -213469633.41 | NA | -212915811.74 | -214748447.01 | -214111123.95 | NA | NA | NA | -214902901.80 | -217300489.75 | NA | NA | NA |
| dMePE(16:0_20:4)-H | ME938890 | 167618689.98 | 2717079.15 | NA | NA | NA | NA | NA | NA | 15748005.16 | 14014612.21 | NA | 61155677.26 | 19224572.91 | 5851113.66 |
| dMePE(18:0_20:5)-H | ME938901 | 104064285.95 | NA | 136490562.71 | NA | 118369315.84 | NA | NA | NA | 557634066.58 | NA | 5265085.16 | NA | 581792652.74 | 355131188.50 |
| LPE(22:5)-H | ME938933 | NA | -1597158048.04 | -55820830.19 | -541780087.85 | -723694174.30 | -926522414.07 | NA | NA | NA | -304029005.70 | -307185850.07 | NA | NA | NA |
| LPS(18:0)-H | ME938938 | NA | 106424192.60 | 105715682.97 | 105826728.33 | 105705852.56 | 105337140.63 | NA | NA | NA | NA | 105897341.95 | NA | 2621545.52 | NA |
| Cer(d18:1_16:0)-H | ME938872 | 5297186572.33 | 5274503014.00 | NA | 5273545108.33 | 5299522440.67 | 5298664411.33 | NA | NA | NA | 5261505604.67 | 5291309972.67 | 5270949167.00 | NA | NA |
| dMePE(18:1_20:2)-H | ME938904 | NA | NA | -37010322.76 | -109874485.72 | -83070125.11 | -785605315.81 | NA | NA | -331506262.19 | NA | NA | -179752241.17 | -412042496.35 | -242589787.20 |
| LPE(22:4)-H | ME938932 | -3103308571.00 | -5031115215.50 | -3193981840.50 | -3557175011.50 | -3526672809.00 | -3625679728.00 | NA | NA | NA | -3797692255.50 | -3063855833.50 | -3140644622.50 | NA | -2722947672.50 |
| Cer(d18:1_24:1)+HCOO | ME938877 | 395127520.40 | 302866661.29 | 130765953.43 | 171225927.93 | 153987775.59 | 164615812.10 | NA | NA | NA | 196780743.31 | 226288648.60 | 159733828.14 | NA | NA |
| LPE(18:1D7)-H | ME938924 | NA | -162739626.65 | -50567455.05 | -159660393.22 | NA | -35611165.49 | NA | NA | NA | NA | -73001890.96 | -116331144.34 | NA | -51007348.87 |
Factors:
| F1 | Variant/Subject:PSMC5 AM (Pittsburgh) | alteration in PSMC5 protein:R201W | comment:Patient |
| F2 | Variant/Subject:PSMC5 BC (Pittsburgh) | alteration in PSMC5 protein:None | comment:Control/mother of AM |
| F3 | Variant/Subject:PSMC5 BLG (Montpellier) | alteration in PSMC5 protein:R325W | comment:Patient |
| F4 | Variant/Subject:PSMC5 BN (Angers) | alteration in PSMC5 protein:E205V | comment:Patient |
| F5 | Variant/Subject:PSMC5 Bro (Prague) | alteration in PSMC5 protein:None | comment:Control/Brother of DelExon4 |
| F6 | Variant/Subject:PSMC5 Bro (Prague) | alteration in PSMC5 protein:None | comment:Control/Brother of DelExon5 |
| F7 | Variant/Subject:PSMC5 Bro (Prague) | alteration in PSMC5 protein:None | comment:Control/Brother of DelExon6 |
| F8 | Variant/Subject:PSMC5 Bro (Prague) | alteration in PSMC5 protein:None | comment:Control/Brother of DelExon7 |
| F9 | Variant/Subject:PSMC5 DelExon4 (Prague) | alteration in PSMC5 protein:Delta Exon 4 | comment:Patient |
| F10 | Variant/Subject:PSMC5 FN (Angers) | alteration in PSMC5 protein:None | comment:Control/father of BN |
| F11 | Variant/Subject:PSMC5 JFL (Nantes) | alteration in PSMC5 protein:PSMD11 R90* | comment:Control/father of LL |
| F12 | Variant/Subject:PSMC5 JLG (Montpellier) | alteration in PSMC5 protein:None | comment:Control/father of BLG |
| F13 | Variant/Subject:PSMC5 JS (New-York) | alteration in PSMC5 protein:P320R | comment:Patient |
| F14 | Variant/Subject:PSMC5 LL (Nantes) | alteration in PSMC5 protein:PSMD11R90*/Q221R | comment:Patient |
