Metabolomics Workbench : NIH Data Repository

Clustering data with hclust algorithm for (Study ST004239)

(Analysis AN007056)

Metabolite	Structure	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12	F13	F14	F15	F16	F17	F18
creatinine	ME1147896	0.02	0.02	0.03	0.04	0.01	0.01	0.18	0.21	0.15	0.20	0.19	0.19	5.02	7.25	1.17	3.90	1.99	1.00
anserine	ME1147850	NA	0.18	NA	0.14	NA	NA	NA	8.04	NA	NA	NA	0.33	0.70	0.88	0.68	0.95	0.63	0.83
cotinine	ME1147894	0.77	0.72	0.55	0.90	0.61	1.11	0.67	0.74	6.21	0.47	0.94	0.34	0.87	1.52	0.74	0.97	0.70	NA
homocysteine	ME1147912	0.59	0.96	2.41	NA	2.45	3.24	1.35	NA	0.38	0.18	0.30	0.74	NA	NA	NA	NA	NA	NA
thymidine	ME1147948	0.87	0.53	2.73	0.58	0.98	0.78	1.54	1.08	0.72	0.67	1.30	0.60	NA	NA	NA	NA	NA	NA
histamine	ME1147910	0.72	0.76	0.49	1.10	0.44	0.64	0.89	3.61	0.58	0.68	0.73	0.75	1.63	1.27	0.39	0.60	0.94	0.55
anthranilic acid	ME1147851	1.34	2.62	NA	NA	0.75	0.86	1.16	0.93	1.19	0.18	1.17	1.18	0.28	0.73	NA	0.38	0.44	1.03
proline[13]C1[15]N1	ME1147936	0.40	NA	0.90	0.32	0.64	0.77	1.38	NA	2.90	1.88	2.16	2.19	0.13	0.02	0.51	0.24	0.37	0.41
phenylalanine-d8	ME1147831	1.09	1.07	1.19	1.03	1.02	1.18	0.94	0.93	1.12	0.96	1.05	1.12	0.80	0.92	0.94	0.81	0.88	0.84
valine-d8	ME1147832	1.04	1.00	1.08	0.97	0.98	1.10	0.97	0.97	1.07	0.99	1.03	1.10	0.90	0.97	0.96	0.89	0.91	0.92
alpha-glycerophosphocholine	ME1147849	0.97	0.92	0.64	0.84	0.60	0.49	1.48	1.51	1.00	1.16	1.01	0.87	0.79	1.05	0.88	1.02	0.96	0.81
C20 carnitine	ME1147884	0.65	0.60	0.73	0.68	0.64	0.57	1.06	1.05	0.96	0.98	1.03	1.06	1.17	1.44	1.45	1.28	1.28	1.03
C18 carnitine	ME1147881	0.72	0.73	0.44	0.68	0.55	0.53	1.17	1.25	0.81	1.09	1.09	0.94	0.84	0.83	2.44	0.93	1.07	1.55
5-aminolevulinic acid	ME1147842	0.11	0.21	0.10	0.09	0.15	0.16	1.29	1.30	1.19	1.24	1.32	1.31	0.80	0.94	2.06	0.93	1.76	1.40
trans-hydroxyproline	ME1147949	0.11	0.21	0.10	0.09	0.15	0.16	1.29	1.30	1.19	1.25	1.32	1.31	0.80	0.94	2.06	0.93	1.76	1.40
choline	ME1147889	0.79	0.22	0.26	0.57	0.29	0.10	2.23	1.39	0.80	1.94	1.48	0.71	0.74	0.73	0.90	0.80	0.75	0.75
threonine	ME1147947	0.29	0.44	0.44	0.42	0.48	0.31	1.38	1.42	1.01	1.19	1.28	1.24	1.05	1.14	0.83	1.02	0.87	0.74
valine	ME1147956	0.32	0.43	0.29	0.31	0.37	0.34	1.38	1.67	0.95	1.22	1.43	1.42	0.94	1.49	0.80	0.91	0.89	0.77
serine	ME1147943	0.28	0.30	0.45	0.41	0.18	0.25	1.38	1.48	0.93	1.29	1.34	1.21	1.17	1.07	1.21	1.15	1.18	1.06
leucine	ME1147915	0.38	0.54	0.28	0.37	0.42	0.37	1.09	1.36	0.88	0.97	1.25	1.17	1.40	1.53	1.25	1.43	1.39	1.20
phenylalanine	ME1147927	0.35	0.52	0.29	0.35	0.40	0.35	1.18	1.51	0.95	1.03	1.35	1.30	1.14	1.53	1.08	1.13	1.24	0.98
trans-hydroxyproline[13]C1[15]N1	ME1147951	0.58	NA	0.28	0.54	0.39	0.45	1.53	1.48	0.94	1.16	1.39	1.16	0.72	0.77	1.24	0.93	0.79	0.88
methionine sulfoxide	ME1147918	0.17	0.17	0.35	0.19	0.07	0.11	1.43	1.68	1.03	1.16	1.30	1.29	1.00	0.90	1.08	0.86	0.89	0.84
asparagine	ME1147857	0.15	0.20	0.10	0.14	0.15	0.14	1.55	1.55	1.32	1.38	1.57	1.50	0.74	0.78	1.27	0.78	0.89	0.92
trans-hydroxyproline[15]N	ME1147950	0.15	0.20	0.10	0.14	0.15	0.14	1.55	1.55	1.32	1.38	1.57	1.50	0.74	0.77	1.27	0.78	0.89	0.92
proline	ME1147934	0.18	0.35	0.17	0.16	0.18	0.20	1.39	1.74	1.19	1.15	1.20	1.28	1.69	2.39	0.27	1.39	0.81	0.29
alanine	ME1147847	0.17	0.20	0.17	0.19	0.17	0.16	1.53	1.56	1.21	1.34	1.53	1.59	1.24	1.69	0.27	1.12	0.80	0.30
tyrosine	ME1147955	0.17	0.24	0.15	0.18	0.17	0.16	1.41	1.69	1.10	1.11	1.37	1.33	1.20	2.19	0.88	1.05	0.89	0.72
5-hydroxytryptophan	ME1147843	NA	NA	NA	NA	NA	NA	1.20	1.56	0.91	0.77	1.60	1.55	0.85	1.36	0.49	0.73	0.55	0.55
glutamine[15]N	ME1147906	NA	0.31	NA	NA	NA	NA	1.39	1.58	0.88	1.28	1.25	1.05	0.75	0.87	0.19	0.74	0.79	0.25
glutamine	ME1147905	0.05	0.31	0.04	0.04	0.04	0.03	1.76	2.01	1.13	1.63	1.59	1.33	0.95	1.13	0.25	0.95	0.97	0.34
pyroglutamic acid	ME1147939	0.04	0.32	0.04	0.04	0.03	0.03	1.76	2.02	1.12	1.63	1.59	1.32	0.97	1.14	0.24	0.96	0.99	0.34
5-adenosylhomocysteine	ME1147841	0.89	1.02	1.09	0.75	1.16	1.56	1.05	0.94	0.83	0.88	1.11	1.12	NA	NA	NA	NA	0.02	NA
carnosine	ME1147888	1.44	1.86	0.77	1.30	1.24	1.26	1.16	1.35	0.46	1.03	1.12	0.84	0.09	0.13	0.07	0.15	0.08	0.07
niacinamide	ME1147921	1.27	0.95	1.10	1.14	0.82	0.91	1.29	1.28	1.66	1.16	1.40	1.50	0.21	0.26	0.18	0.22	0.23	0.14
pipecolic acid	ME1147930	0.77	0.79	0.87	0.53	0.68	0.85	1.57	1.69	1.32	1.38	1.45	1.74	0.04	0.05	0.02	0.04	0.03	0.02
putrescine	ME1147938	1.18	1.20	0.64	1.03	0.98	0.80	1.63	1.67	1.31	1.53	1.54	1.38	0.01	0.02	0.00	0.01	0.01	0.00
s-adenosylmethionine	ME1147940	0.80	1.04	0.65	0.74	1.00	1.09	1.77	1.47	1.09	1.36	1.81	1.49	0.14	0.15	0.12	0.12	0.12	0.08
adenosine	ME1147845	0.98	0.97	0.84	0.98	0.91	1.05	1.27	1.33	1.15	1.51	1.60	1.57	0.29	0.27	0.20	0.22	0.26	0.15
spermidine	ME1147944	0.90	0.97	0.92	0.88	0.91	0.99	1.50	1.45	1.47	1.43	1.49	1.50	0.14	0.21	0.08	0.13	0.11	0.08
GABA	ME1147899	0.68	0.81	0.44	0.53	0.46	0.54	1.28	1.37	2.28	1.46	1.57	2.29	0.00	0.00	0.00	0.00	0.00	0.00
phosphocholine	ME1147928	0.55	0.44	0.73	0.55	0.88	0.82	1.45	1.13	1.84	1.43	2.23	1.92	0.01	0.02	0.01	0.01	0.01	0.01
glutamate[15]N	ME1147902	0.59	0.81	NA	0.45	0.45	NA	0.90	1.28	1.08	0.91	1.19	1.08	NA	NA	NA	NA	NA	NA
phosphoethanolamine	ME1147929	0.33	0.34	1.02	0.31	0.46	0.82	0.90	0.81	2.24	0.78	1.21	1.91	0.02	0.05	NA	NA	NA	NA
cAMP	ME1147887	0.51	0.43	0.98	0.33	NA	0.57	1.21	0.90	1.13	0.72	1.37	1.49	NA	NA	NA	NA	NA	NA
2-deoxycytidine	ME1147840	0.42	0.63	0.91	0.38	0.65	0.85	0.86	1.42	1.29	0.96	1.20	1.35	NA	NA	NA	NA	NA	NA
cytosine	ME1147897	0.49	0.70	0.89	0.42	0.70	0.87	0.87	1.42	1.29	0.91	1.19	1.30	NA	NA	NA	NA	NA	NA
SDMA	ME1147942	0.82	0.76	0.62	0.70	0.74	0.77	1.57	1.56	1.12	1.46	1.46	1.31	0.52	1.40	0.06	0.39	0.19	0.08
thiamine	ME1147946	0.11	0.09	0.10	0.12	0.18	0.15	1.81	1.59	1.42	1.70	2.31	2.39	0.04	0.02	0.40	0.05	0.09	0.22
NMMA	ME1147922	0.35	0.30	0.29	0.24	0.28	0.37	1.89	1.77	1.09	1.49	2.01	2.16	0.30	0.39	0.07	0.23	0.24	0.10
ADMA	ME1147846	0.63	0.56	0.49	0.53	0.60	0.69	1.93	1.79	1.17	1.62	1.80	1.66	0.13	0.20	0.03	0.09	0.08	0.03
methylthioadenosine	ME1147919	0.53	0.44	0.29	0.48	0.63	0.59	1.75	1.66	1.06	1.66	2.08	1.86	0.20	0.22	0.12	0.15	0.08	0.10
arginine	ME1147852	0.39	1.19	0.22	0.28	0.24	0.24	1.62	2.22	1.73	1.45	1.55	1.59	0.14	0.76	0.03	0.07	0.09	0.04
glutamate	ME1147901	0.62	1.08	0.20	0.41	0.42	0.33	1.60	2.03	1.38	1.52	1.77	1.59	0.15	0.13	0.29	0.17	0.19	0.25
histidine	ME1147911	0.27	0.43	0.34	0.23	0.24	0.38	1.61	1.35	1.56	1.35	1.81	1.89	0.46	0.51	0.51	0.49	0.55	0.43
lysine	ME1147916	0.33	0.31	0.25	0.23	0.27	0.33	1.77	1.59	1.62	1.28	1.62	2.15	0.31	0.41	0.47	0.31	0.36	0.35
arginine[15]N	ME1147853	0.50	0.91	0.42	0.38	0.38	0.41	1.46	1.75	1.66	1.32	1.41	1.54	0.38	0.57	0.49	0.38	0.46	0.43
aspartate	ME1147858	0.61	0.72	0.39	0.48	0.55	0.54	1.51	1.67	1.21	1.35	1.48	1.46	0.48	0.62	0.61	0.56	0.56	0.52
proline[15]N	ME1147935	0.13	0.01	0.09	0.11	0.11	0.12	0.41	0.02	1.00	0.56	0.83	1.03	1.32	0.08	4.73	2.32	3.46	3.82
glutamine[13]C5	ME1147908	0.51	0.03	0.34	0.51	0.46	0.50	0.56	0.01	1.97	0.57	1.04	1.63	0.50	0.24	3.87	0.77	1.66	2.46
ornithine[13]C1[15]N1	ME1147925	0.03	0.03	0.08	0.02	0.04	0.07	0.36	0.01	1.79	0.54	0.98	1.48	0.95	0.07	4.35	1.59	2.32	2.87
butyrobetaine	ME1147861	NA	NA	NA	NA	NA	NA	0.73	0.71	0.82	0.75	0.76	0.84	1.15	2.66	NA	0.95	1.53	NA
ornithine	ME1147923	0.07	0.13	0.11	0.08	0.05	0.08	1.22	1.53	1.61	1.03	1.02	1.17	1.69	4.65	0.15	1.07	0.58	0.18
allantoin	ME1147848	0.64	NA	0.10	0.22	NA	0.13	0.49	0.22	0.05	0.11	0.12	0.09	2.96	4.60	0.24	2.12	1.13	0.31
glucose	ME1147900	NA	2.02	0.30	0.71	0.13	NA	NA	0.36	0.35	0.42	0.45	0.46	2.12	3.41	0.58	1.11	0.62	0.25
C16 carnitine	ME1147880	0.20	0.19	0.08	0.20	0.14	0.12	0.56	0.56	0.26	0.54	0.50	0.39	2.37	2.28	4.42	2.44	2.62	3.30
C3 carnitine	ME1147864	0.01	0.01	0.02	0.01	0.01	0.01	0.38	0.47	0.47	0.36	0.45	0.56	3.41	2.99	2.74	3.26	2.92	2.52
taurine	ME1147945	0.05	0.05	0.09	0.10	0.03	0.03	0.29	0.30	0.17	0.23	0.23	0.24	3.59	3.93	2.86	3.78	3.32	2.65
C18:2 carnitine	ME1147883	0.08	0.05	NA	0.05	0.04	0.04	0.36	0.36	0.16	0.32	0.31	0.23	3.44	3.63	2.66	3.41	3.19	2.63
carnitine	ME1147862	0.02	0.02	0.02	0.02	0.01	0.01	0.47	0.46	0.33	0.41	0.43	0.39	3.70	3.39	2.65	3.63	3.05	2.53
arginine[13]C1[15]N1	ME1147854	0.87	0.05	1.13	0.70	0.88	1.00	0.84	0.02	1.34	0.91	1.07	1.23	1.23	0.17	2.08	1.45	1.76	1.82
1-pyrroline-5-carboxylate[13]C5	ME1147839	NA	NA	NA	NA	NA	NA	0.26	NA	0.86	0.36	0.58	0.84	0.50	NA	2.12	1.01	1.50	1.73
C10 carnitine	ME1147873	NA	NA	0.11	NA	NA	NA	0.32	0.64	NA	NA	NA	NA	1.29	1.04	0.88	1.07	1.21	1.15
C14:2 carnitine	ME1147879	NA	NA	NA	NA	NA	NA	0.25	0.20	NA	NA	0.28	NA	1.18	1.14	0.71	1.54	1.65	1.06
C20:4 carnitine	ME1147885	0.10	NA	NA	0.06	NA	NA	0.35	0.34	0.09	0.31	0.38	0.17	2.36	2.20	2.10	2.52	2.45	2.20
betaine	ME1147860	0.07	0.08	0.08	0.07	0.08	0.08	0.67	0.67	0.55	0.63	0.67	0.66	2.69	2.80	2.67	2.79	2.57	2.30
C2 carnitine	ME1147863	0.02	0.01	0.01	0.01	0.01	0.01	0.82	0.78	0.64	0.72	0.78	0.74	2.77	2.50	2.62	2.68	2.23	2.18
creatine	ME1147895	0.01	0.02	0.02	0.02	0.01	0.01	0.74	0.76	0.66	0.73	0.75	0.74	2.58	2.61	2.51	2.64	2.65	2.18
sarcosine	ME1147941	0.02	0.04	0.03	0.04	0.02	0.03	0.69	0.70	0.63	0.68	0.71	0.72	2.49	2.53	2.27	2.55	2.45	1.98
C14 carnitine	ME1147877	0.09	0.08	0.11	0.11	0.13	0.10	0.70	0.69	0.35	0.64	0.65	0.51	2.01	1.98	3.08	2.09	2.26	2.79
C18:1 carnitine	ME1147882	0.31	0.29	0.15	0.31	0.22	0.21	0.71	0.72	0.40	0.67	0.67	0.53	2.38	2.35	3.07	2.43	2.38	2.51
C14:1 carnitine	ME1147878	NA	NA	NA	NA	NA	NA	0.73	0.52	0.30	0.55	0.60	0.45	1.59	1.27	1.91	1.86	2.36	2.37
C6 carnitine	ME1147870	NA	NA	NA	NA	NA	NA	0.61	0.53	0.41	0.61	0.60	0.50	1.25	0.88	2.59	1.54	2.46	2.76
C12 carnitine	ME1147875	NA	NA	NA	NA	NA	NA	0.53	0.33	0.29	0.51	0.49	0.33	1.15	1.00	1.68	1.39	1.72	1.64
ornithine[15]N	ME1147924	NA	NA	NA	NA	NA	NA	0.61	0.52	0.78	0.58	0.60	0.64	0.93	1.79	2.03	0.99	1.11	1.30
1-pyrroline-5-carboxylate	ME1147836	NA	NA	NA	NA	NA	NA	0.89	0.92	0.98	0.72	0.98	0.86	0.77	1.23	1.50	1.01	1.64	1.18
C4-OH carnitine	ME1147867	NA	NA	NA	NA	NA	NA	0.93	0.88	0.72	0.83	0.87	0.81	1.40	1.34	1.50	1.39	1.15	1.14
C5:1 carnitine	ME1147869	NA	NA	NA	NA	NA	NA	0.77	0.73	0.71	0.73	0.74	0.72	1.56	1.57	1.52	1.53	1.54	1.48
beta-alanine	ME1147859	0.11	0.13	NA	0.14	0.05	0.17	0.83	0.86	0.48	0.97	0.99	1.49	1.71	2.07	1.11	1.67	1.56	1.12
1-pyrroline-5-carboxylase[15]N	ME1147837	NA	NA	NA	NA	NA	NA	0.35	0.52	0.53	0.56	0.61	0.60	1.72	1.93	2.01	2.06	1.89	1.58
C4 carnitine	ME1147866	NA	NA	NA	NA	NA	NA	0.61	0.57	0.43	0.59	0.61	0.52	2.00	1.75	1.96	2.02	1.85	1.75
C5 carnitine	ME1147868	NA	NA	NA	NA	NA	NA	0.68	0.63	0.54	0.63	0.65	0.60	1.89	1.66	1.77	1.82	1.79	1.61
isoleucine	ME1147913	0.19	0.22	0.17	0.18	0.17	0.17	0.82	0.82	0.90	0.70	0.92	0.94	2.25	1.84	2.12	2.32	2.28	1.91
methionine	ME1147917	0.19	0.25	0.11	0.18	0.18	0.14	0.86	0.94	0.71	0.72	0.95	0.82	2.15	2.34	2.09	2.28	2.24	1.84
tryptophan	ME1147954	0.13	0.19	0.15	0.16	0.13	0.12	1.01	1.21	0.84	0.88	1.03	1.03	1.77	2.47	1.85	1.66	1.77	1.58
C3-DC-CH3 carnitine	ME1147865	0.15	0.16	0.08	0.12	0.12	0.10	1.03	1.04	0.86	1.00	1.00	0.94	1.98	2.08	1.90	2.09	1.90	1.62
glycine	ME1147909	0.18	0.23	0.21	0.22	0.17	0.17	0.99	1.04	0.66	0.94	0.96	0.91	2.21	2.31	1.58	2.24	1.98	1.51
citrulline[13]C5	ME1147893	0.66	0.33	2.10	1.18	NA	0.75	0.28	0.68	0.08	0.42	0.95	0.25	1.73	1.55	1.13	1.41	1.42	1.11
citrulline	ME1147890	0.48	0.47	1.93	1.29	0.27	0.84	0.43	0.73	0.21	0.53	0.46	0.43	2.47	2.47	1.73	2.32	2.41	1.75
C26 carnitine	ME1147886	0.61	0.56	0.56	0.62	0.65	0.61	0.93	0.97	0.75	0.79	0.89	0.81	1.83	2.11	1.52	1.80	1.50	1.32
1-methylnicotinamide	ME1147835	0.71	0.74	0.76	0.68	0.74	0.72	0.64	0.70	0.76	0.62	0.63	0.80	1.91	2.05	1.75	1.97	1.98	1.69
trimethylamine-N-oxide	ME1147953	0.82	0.83	0.95	0.79	0.80	0.86	0.72	0.72	0.74	0.72	0.67	0.72	1.94	1.96	1.42	1.87	1.76	1.40

Factors:

F1	Sample source:free parasites \| Parasite_type:Saponin \| Parasite_line:Dd2 \| Timepoint:0.5 h
F2	Sample source:free parasites \| Parasite_type:Saponin \| Parasite_line:Dd2 \| Timepoint:0 h
F3	Sample source:free parasites \| Parasite_type:Saponin \| Parasite_line:Dd2 \| Timepoint:10 h
F4	Sample source:free parasites \| Parasite_type:Saponin \| Parasite_line:Dd2 \| Timepoint:1 h
F5	Sample source:free parasites \| Parasite_type:Saponin \| Parasite_line:Dd2 \| Timepoint:2 h
F6	Sample source:free parasites \| Parasite_type:Saponin \| Parasite_line:Dd2 \| Timepoint:6 h
F7	Sample source:infected RBC (iRBC) \| Parasite_type:iRBC \| Parasite_line:Dd2 \| Timepoint:0.5 h
F8	Sample source:infected RBC (iRBC) \| Parasite_type:iRBC \| Parasite_line:Dd2 \| Timepoint:0 h
F9	Sample source:infected RBC (iRBC) \| Parasite_type:iRBC \| Parasite_line:Dd2 \| Timepoint:10 h
F10	Sample source:infected RBC (iRBC) \| Parasite_type:iRBC \| Parasite_line:Dd2 \| Timepoint:1 h
F11	Sample source:infected RBC (iRBC) \| Parasite_type:iRBC \| Parasite_line:Dd2 \| Timepoint:2 h
F12	Sample source:infected RBC (iRBC) \| Parasite_type:iRBC \| Parasite_line:Dd2 \| Timepoint:6 h
F13	Sample source:uninfected RBC (uRBC) \| Parasite_type:uninfected RBCs \| Parasite_line:Control RBCs \| Timepoint:0.5 h
F14	Sample source:uninfected RBC (uRBC) \| Parasite_type:uninfected RBCs \| Parasite_line:Control RBCs \| Timepoint:0 h
F15	Sample source:uninfected RBC (uRBC) \| Parasite_type:uninfected RBCs \| Parasite_line:Control RBCs \| Timepoint:10 h
F16	Sample source:uninfected RBC (uRBC) \| Parasite_type:uninfected RBCs \| Parasite_line:Control RBCs \| Timepoint:1 h
F17	Sample source:uninfected RBC (uRBC) \| Parasite_type:uninfected RBCs \| Parasite_line:Control RBCs \| Timepoint:2 h
F18	Sample source:uninfected RBC (uRBC) \| Parasite_type:uninfected RBCs \| Parasite_line:Control RBCs \| Timepoint:6 h

Data matrix