Clustering data with hclust algorithm for (Study ST003256)
(Analysis AN005338)| Metabolite | Structure | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| PC 16:0/20:4;O3 | ME856578 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.18 | 0.50 | 0.64 | 0.49 | 0.15 | 1.61 | 2.67 | 2.49 | 0.21 | 1.13 | 3.43 | 3.17 |
| PC 18:0/22:4;O | ME856585 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.03 | 1.62 | 2.20 | 1.66 | 0.87 | 1.52 | 1.64 | 1.38 | 0.94 | 0.85 | 1.85 | 1.16 |
| PC 18:1/20:4;O | ME856582 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.96 | 0.82 | 1.10 | 1.10 | 0.72 | 1.52 | 2.79 | 2.25 | 0.90 | 0.79 | 2.61 | 2.32 |
| PC 16:0/22:4;O | ME856584 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.78 | 1.15 | 1.26 | 0.86 | 0.88 | 1.15 | 2.28 | 1.74 | 1.39 | 0.99 | 2.52 | 1.73 |
| PC 16:0/20:4;O | ME856576 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.18 | 0.86 | 1.41 | 1.32 | 0.80 | 1.40 | 2.50 | 1.83 | 1.12 | 0.78 | 2.64 | 1.99 |
| PC 18:0/20:4;O | ME856579 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 1.23 | 0.78 | 1.20 | 1.18 | 1.16 | 1.35 | 2.29 | 1.88 | 1.39 | 0.84 | 2.65 | 1.92 |
| PC 18:0/20:4;O3 | ME856581 | 0.00 | 0.00 | 0.00 | NA | 0.00 | 0.00 | 0.19 | 0.52 | 0.74 | 0.66 | 0.64 | 1.65 | 3.58 | 2.18 | 0.30 | 1.30 | 2.70 | 1.04 |
| PC 18:0/20:4;O2 | ME856580 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.54 | 0.96 | 1.47 | 1.14 | 0.89 | 2.40 | 2.52 | 1.65 | 0.99 | 1.10 | 1.96 | 1.26 |
| PC 16:0/20:4;O2 | ME856577 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.30 | 0.70 | 1.14 | 1.03 | 0.50 | 2.61 | 3.24 | 2.13 | 0.81 | 1.05 | 2.28 | 1.44 |
| PC 18:1/20:4;O2 | ME856583 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.00 | 0.27 | 0.71 | 1.11 | 0.80 | 0.48 | 2.51 | 3.17 | 2.05 | 0.70 | 1.09 | 2.60 | 1.45 |
| PI 18:1/20:4;O2 | ME856593 | 1.22 | 1.24 | 1.67 | 0.07 | 0.30 | 0.59 | NA | 0.87 | NA | NA | NA | 0.85 | NA | NA | NA | 1.59 | NA | NA |
| PI 18:0/20:4;O3 | ME856591 | 0.51 | 2.42 | 2.35 | 0.02 | 0.04 | 0.03 | NA | 0.36 | NA | NA | NA | 1.84 | NA | NA | NA | 1.43 | NA | NA |
| PI 18:0/22:4;O3* | ME856598 | 0.58 | 2.22 | 2.13 | 0.03 | 0.02 | 0.03 | NA | 0.36 | NA | NA | NA | 1.98 | NA | NA | NA | 1.66 | NA | NA |
| PI 18:0/20:4;O2 | ME856590 | 1.02 | 2.18 | 2.13 | 0.06 | 0.10 | 0.08 | NA | 0.57 | NA | NA | NA | 1.66 | NA | NA | NA | 1.20 | NA | NA |
| PI 18:0/22:4;O2* | ME856597 | 0.60 | 2.15 | 2.13 | 0.10 | 0.12 | 0.05 | NA | 0.58 | NA | NA | NA | 1.73 | NA | NA | NA | 1.23 | NA | NA |
| PI 18:1/20:4;O3 | ME856594 | 0.72 | 2.33 | 2.29 | 0.04 | 0.13 | 0.06 | NA | 0.52 | NA | NA | NA | 1.61 | NA | NA | NA | 0.99 | NA | NA |
| PI 18:0/22:4;O | ME856596 | 1.12 | 1.90 | 1.79 | 0.15 | 0.14 | 0.11 | NA | 0.73 | NA | NA | NA | 1.58 | NA | NA | NA | 1.47 | NA | NA |
| PI 18:0/20:4;O | ME856589 | 0.89 | 1.90 | 2.22 | 0.12 | 0.14 | 0.14 | NA | 0.66 | NA | NA | NA | 1.59 | NA | NA | NA | 1.34 | NA | NA |
| PI 18:1/20:4;O | ME856592 | 0.84 | 1.92 | 1.96 | 0.31 | 0.24 | 0.25 | NA | 0.63 | NA | NA | NA | 1.56 | NA | NA | NA | 1.29 | NA | NA |
| PI 16:0/20:4;O | ME856586 | 1.02 | 1.99 | 1.60 | 0.41 | 0.56 | 0.59 | NA | 0.29 | NA | NA | NA | 1.53 | NA | NA | NA | 1.01 | NA | NA |
| PI 16:0/20:4;O3 | ME856588 | 0.96 | 1.30 | 1.46 | 0.77 | 0.29 | 0.38 | NA | 0.48 | NA | NA | NA | 1.45 | NA | NA | NA | 1.34 | NA | NA |
| PE 18:1/20:4;O3 | ME856569 | 0.39 | 2.14 | 1.98 | 0.04 | 0.13 | 0.08 | 0.19 | 0.24 | 0.19 | 0.14 | 0.08 | 2.15 | 2.14 | 1.43 | 0.45 | 1.84 | 2.71 | 1.50 |
| PE 16:0/22:4;O3* | ME856572 | 0.43 | 2.69 | 3.05 | 0.06 | 0.16 | 0.11 | 0.15 | 0.17 | 0.33 | 0.20 | 0.07 | 1.70 | 1.61 | 1.08 | 0.41 | 1.27 | 2.27 | 1.27 |
| PE 18:0/22:4;O3* | ME856575 | 0.64 | 2.87 | 2.68 | 0.07 | 0.12 | 0.10 | 0.17 | 0.31 | 0.18 | 0.15 | 0.16 | 1.85 | 1.72 | 1.33 | 0.27 | 1.78 | 2.16 | 1.52 |
| PE 16:0/20:4;O3 | ME856563 | 0.46 | 2.71 | 2.92 | 0.06 | 0.20 | 0.15 | 0.18 | 0.22 | 0.18 | 0.17 | 0.15 | 2.13 | 1.67 | 0.91 | 0.33 | 2.02 | 2.14 | 1.10 |
| PE 18:0/20:4;O3 | ME856566 | 0.50 | 2.46 | 2.64 | 0.05 | 0.08 | 0.08 | 0.18 | 0.33 | 0.18 | 0.16 | 0.12 | 2.01 | 1.78 | 1.02 | 0.33 | 2.11 | 2.29 | 1.23 |
| PE 16:0/22:4;O | ME856570 | 1.60 | 1.96 | 3.17 | 0.38 | 0.65 | 0.54 | 0.25 | 0.59 | 0.48 | 0.33 | 0.17 | 2.05 | 0.92 | 0.43 | 0.29 | 1.92 | 1.01 | 0.47 |
| PE 18:0/22:4;O2* | ME856574 | 0.85 | 2.23 | 2.60 | 0.05 | 0.12 | 0.07 | 0.35 | 0.65 | 0.37 | 0.31 | 0.30 | 2.00 | 1.48 | 0.81 | 0.39 | 1.81 | 1.84 | 0.98 |
| PE 18:1/20:4;O2 | ME856568 | 1.36 | 2.21 | 2.85 | 0.05 | 0.06 | 0.04 | 0.46 | 0.64 | 0.43 | 0.56 | 0.43 | 1.90 | 1.21 | 0.71 | 0.52 | 1.70 | 1.43 | 0.81 |
| PE 18:0/22:4;O | ME856573 | 1.57 | 1.44 | 1.61 | 0.64 | 0.61 | 0.62 | 1.69 | 1.14 | 1.14 | 1.23 | 0.35 | 0.95 | 0.75 | 0.54 | 0.52 | 1.00 | 0.92 | 0.63 |
| PE 16:0/20:4;O2 | ME856562 | 1.14 | 2.02 | 1.73 | 0.31 | 0.31 | 0.16 | 0.41 | 0.78 | 0.97 | 0.38 | 0.42 | 1.40 | 1.19 | 0.50 | 0.36 | 2.10 | 1.83 | 0.85 |
| PE 18:1/20:4;O | ME856567 | 0.60 | 1.45 | 1.63 | 0.21 | 0.33 | 0.27 | 0.48 | 0.68 | 0.71 | 0.69 | 0.53 | 1.75 | 1.69 | 1.14 | 0.71 | 1.58 | 1.82 | 1.28 |
| PE 18:0/20:4;O2 | ME856565 | 0.87 | 1.36 | 1.63 | 0.24 | 0.33 | 0.26 | 0.98 | 0.83 | 0.97 | 0.98 | 0.75 | 1.36 | 1.40 | 0.97 | 0.71 | 1.28 | 1.60 | 1.13 |
| PE 16:0/20:4;O | ME856561 | 1.13 | 1.67 | 1.85 | 0.39 | 0.46 | 0.40 | 0.56 | 0.78 | 0.78 | 0.94 | 0.51 | 1.37 | 1.23 | 1.07 | 0.67 | 1.37 | 1.49 | 1.23 |
| PE 18:0/20:4;O | ME856564 | 1.29 | 1.82 | 1.98 | 0.35 | 0.37 | 0.37 | 0.74 | 0.80 | 0.66 | 0.65 | 0.42 | 1.41 | 1.28 | 0.94 | 0.64 | 1.39 | 1.53 | 1.08 |
Factors:
| F1 | Sample source:Breast cancer cells | Genotype:shCtrl | Treatment:DMSO | Treatment Time:2 h |
| F2 | Sample source:Breast cancer cells | Genotype:shCtrl | Treatment:RSL3 (10 µM) | Treatment Time:2 h |
| F3 | Sample source:Breast cancer cells | Genotype:shCtrl | Treatment:RSL3 (1 µM) | Treatment Time:2 h |
| F4 | Sample source:Breast cancer cells | Genotype:shZeb1 | Treatment:DMSO | Treatment Time:2 h |
| F5 | Sample source:Breast cancer cells | Genotype:shZeb1 | Treatment:RSL3 (10 µM) | Treatment Time:2 h |
| F6 | Sample source:Breast cancer cells | Genotype:shZeb1 | Treatment:RSL3 (1 µM) | Treatment Time:2 h |
| F7 | Sample source:Breast cancer cells | Genotype:WT | Treatment:DMSO | Treatment Time:24 h |
| F8 | Sample source:Breast cancer cells | Genotype:WT | Treatment:DMSO | Treatment Time:2 h |
| F9 | Sample source:Breast cancer cells | Genotype:WT | Treatment:DMSO | Treatment Time:4 h |
| F10 | Sample source:Breast cancer cells | Genotype:WT | Treatment:DMSO | Treatment Time:6 h |
| F11 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (10 µM) | Treatment Time:24 h |
| F12 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (10 µM) | Treatment Time:2 h |
| F13 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (10 µM) | Treatment Time:4 h |
| F14 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (10 µM) | Treatment Time:6 h |
| F15 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (1 µM) | Treatment Time:24 h |
| F16 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (1 µM) | Treatment Time:2 h |
| F17 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (1 µM) | Treatment Time:4 h |
| F18 | Sample source:Breast cancer cells | Genotype:WT | Treatment:RSL3 (1 µM) | Treatment Time:6 h |
