Data for (Study ST003642)
(Analysis AN005981)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 1_3-Bisphosphoglyceric acid | 0.7310 | 0.9096 | 1.2794 | 0.8006 |
| 2_3-Diphosphoglyceric acid | 1.4549 | 1.8165 | 0.0662 | 1.5961 |
| 3-phosphoglycerate | 1.3339 | 1.4680 | 0.2725 | 1.6531 |
| 3-phospho-serine | 0.9783 | 0.9052 | 1.1840 | 0.7485 |
| 4-aminobutyrate | 0.6778 | 0.7644 | 1.4631 | 0.6316 |
| 4-phosphopantothenate | 0.9698 | 1.0016 | 1.0913 | 0.8687 |
| 4-Pyridoxic acid | 0.1323 | 0.1431 | 2.2978 | 0.1290 |
| 5-aminopentanoic acid | 1.2760 | 1.7500 | 0.4844 | 1.0052 |
| 5-phosphoribosyl-1-pyrophosphate | 0.6431 | 1.1793 | 1.3225 | 0.6131 |
| 6-phospho-D-gluconate | 0.0605 | 0.0618 | 2.6110 | 0.0584 |
| acetyl-aspartate | 0.4286 | 0.4871 | 1.8511 | 0.3821 |
| acetyl-CoA | 0.2963 | 0.4159 | 2.0863 | 0.3867 |
| Acetyllysine | 1.1901 | 0.9754 | 0.9525 | 0.9295 |
| aconitate | 0.5263 | 0.6182 | 1.6707 | 0.5142 |
| adenine | 0.0141 | 0.0141 | 2.4776 | 0.0165 |
| a-ketoglutarate | 1.5855 | 1.6821 | 0.0790 | 1.5744 |
| alanine/sarcosine | 0.8288 | 0.9394 | 1.3363 | 0.5592 |
| arginine | 1.4359 | 1.4393 | 0.4699 | 1.1850 |
| asparagine | 0.4635 | 0.5051 | 1.8924 | 0.2467 |
| aspartate | 1.7597 | 1.7012 | 0.0551 | 1.4289 |
| CDP | 0.1462 | 0.1540 | 2.6894 | 0.1658 |
| CDP-choline | 0.0052 | 0.0062 | 2.7054 | 0.0041 |
| CDP-ethanolamine | 1.5025 | 1.7674 | 0.0724 | 1.3535 |
| chlorpropamide | 1.0244 | 1.1900 | 0.8779 | 1.0297 |
| CMP | 1.5250 | 1.7381 | 0.2161 | 1.3048 |
| CTP | 1.0215 | 1.1659 | 0.6632 | 1.4019 |
| cytidine | 1.7437 | 1.4183 | 0.0867 | 1.6647 |
| dAMP | 1.5063 | 1.9030 | 0.1518 | 1.0750 |
| dATP | 0.8935 | 0.9947 | 0.9655 | 1.1723 |
| dCDP | 1.2035 | 1.3810 | 0.4365 | 0.9790 |
| dCMP | 1.2657 | 1.4475 | 0.6688 | 0.9491 |
| dCTP | 0.9812 | 0.9930 | 0.9519 | 1.1100 |
| dGDP/ADP | 1.4785 | 1.5534 | 0.1260 | 1.7161 |
| D-gluconate | 1.1103 | 1.3606 | 0.7327 | 1.0637 |
| D-glucosamine-1/6-phosphate | 1.3279 | 1.4436 | 0.5175 | 1.1935 |
| dGMP/AMP | 1.6515 | 1.7647 | 0.0667 | 1.4505 |
| dGTP/ATP | 1.2871 | 1.4744 | 0.1647 | 1.9090 |
| dihydroorotate | 0.2070 | 0.3547 | 2.1300 | 0.1784 |
| dihydroxy-acetone-phosphate | 0.8128 | 1.0141 | 0.8664 | 1.4403 |
| DLH | 1.5711 | 1.5941 | 0.0676 | 1.4665 |
| DL-Pipecolic Acid | 1.8222 | 1.5877 | 0.0441 | 1.5020 |
| DLS | 1.6584 | 1.8469 | 0.0543 | 1.3861 |
| D-sedoheptulose-1/7-phosphate | 1.3724 | 1.8272 | 0.2226 | 1.1609 |
| dTDP | 0.3648 | 0.3775 | 2.1079 | 0.3189 |
| dTMP | 1.1995 | 1.5349 | 0.7071 | 0.7781 |
| dTTP | 1.1494 | 1.1798 | 0.5780 | 1.4094 |
| dUMP | 0.1616 | 0.4221 | 3.3236 | 0.0927 |
| EV | 0.0117 | 0.0146 | 2.4840 | 0.0057 |
| FAD | 0.4150 | 0.4078 | 2.0064 | 0.4160 |
| fructose-1-6-bisphosphate | 0.5321 | 0.7012 | 1.5918 | 0.7311 |
| fumarate | 1.4376 | 1.9347 | 0.1707 | 1.2863 |
| GDP | 0.8797 | 0.9585 | 1.1030 | 0.9558 |
| GDP-Mannose | 1.0212 | 1.7224 | 0.5550 | 1.0351 |
| glutamate | 1.5832 | 1.8602 | 0.0417 | 1.4732 |
| glutamine | 1.4045 | 2.1316 | 0.1482 | 1.1675 |
| glutathione | 1.2201 | 1.4118 | 0.4495 | 1.4692 |
| glutathione disulfide | 1.6204 | 1.7648 | 0.0380 | 1.5388 |
| GMP | 1.6360 | 1.7870 | 0.0354 | 1.5063 |
| guanine | 1.8265 | 1.8472 | 0.0451 | 1.2361 |
| hexose-phosphate | 1.4297 | 1.4246 | 0.4557 | 1.2344 |
| histidine | 0.9014 | 1.2860 | 1.0807 | 0.6513 |
| hydroxyproline/Aminolevulinate | 0.8586 | 1.1385 | 1.0962 | 0.8106 |
| hypoxanthine | 1.6300 | 1.6854 | 0.0508 | 1.5830 |
| IMP | 1.0753 | 1.2056 | 0.9366 | 0.8460 |
| isoleucine | 0.6939 | 1.0144 | 1.2524 | 0.7868 |
| lactate | 1.4412 | 1.4050 | 0.5269 | 1.1000 |
| L-arginino-succinate | 0.2654 | 0.3727 | 2.2521 | 0.1708 |
| LD | 0.2834 | 0.2743 | 2.0854 | 0.2716 |
| leucine | 1.5788 | 1.6076 | 0.1999 | 1.4138 |
| lysine | 0.6747 | 0.7055 | 1.5557 | 0.5084 |
| malate | 1.4773 | 1.9967 | 0.0995 | 1.3270 |
| maleic acid | 1.4544 | 1.9573 | 0.1435 | 1.3014 |
| methionine | 1.3752 | 1.4929 | 0.4161 | 1.2997 |
| myo-inositol | 1.4246 | 1.2820 | 0.7883 | 0.7169 |
| N-acetyl-glucosamine-1/6-phosphate | 1.2165 | 0.4824 | 1.1474 | 1.0431 |
| N-acetyl-glutamate | 1.4776 | 1.7516 | 0.1341 | 1.5025 |
| N-acetyl-glutamine | 1.4232 | 1.5441 | 0.3542 | 1.3242 |
| N-Acetyl-L-alanine | 1.5509 | 1.7423 | 0.1527 | 1.4013 |
| N-acetyl-L-ornithine | 0.7869 | 0.6845 | 1.4609 | 0.6068 |
| NAD+ | 0.5844 | 0.7406 | 1.4893 | 0.6965 |
| NADP+ | 1.3481 | 1.4948 | 0.2840 | 1.4100 |
| N-carbamoyl-L-aspartate | 1.0637 | 1.9398 | 0.2395 | 1.5174 |
| nicotinamide mononucleotide | 0.2666 | 0.3104 | 2.0859 | 0.2512 |
| nicotinate | 1.4321 | 1.4639 | 0.5852 | 0.9337 |
| Octulose 8/1P | 0.9664 | 0.7508 | 1.3052 | 0.7486 |
| Octulose Bisphosphate | 1.1108 | 1.1737 | 0.7514 | 1.0263 |
| ornithine | 0.2367 | 0.2454 | 2.1452 | 0.2276 |
| orotate | 1.0103 | 1.2731 | 0.9112 | 0.8942 |
| PD | 1.6656 | 1.8392 | 0.0548 | 1.3855 |
| PE | 1.6146 | 1.6800 | 0.2031 | 1.2992 |
| PEE | 1.5162 | 1.7303 | 0.1497 | 1.2415 |
| PEEK | 0.0780 | 0.0935 | 2.5806 | 0.0624 |
| Phenol Red | 1.3690 | 1.5499 | 0.3877 | 1.3057 |
| phenylalanine | 1.4114 | 1.4352 | 0.4338 | 1.2858 |
| phosphoenolpyruvate | 1.4628 | 1.3656 | 0.2942 | 1.5832 |
| proline | 1.5466 | 1.4372 | 0.3360 | 1.3441 |
| PTT | 0.0136 | 0.0109 | 2.4822 | 0.0111 |
| PVNF | 1.0043 | 0.8694 | 1.0080 | 1.1102 |
| pyridoxine | 0.9815 | 1.2936 | 0.6585 | 1.4078 |
| Pyroglutamic acid | 1.7354 | 1.4619 | 0.1687 | 1.4653 |
| pyruvate | 1.2796 | 1.2676 | 0.6595 | 1.1338 |
| Ribose-5-phosphate | 1.0640 | 1.2435 | 0.9437 | 0.8051 |
| ribose-phosphate | 0.8107 | 0.9331 | 1.3219 | 0.6124 |
| ribulose-5-phosphate | 1.3033 | 1.7535 | 0.2035 | 1.5363 |
| S-adenosyl-L-homocysteine | 0.1887 | 0.2010 | 2.4240 | 0.1184 |
| SD | 1.4152 | 1.5073 | 0.3441 | 1.2253 |
| SDL | 1.6574 | 1.6347 | 0.1211 | 1.4657 |
| Sedoheptulose bisphosphate | 0.0512 | 0.0604 | 2.6192 | 0.0549 |
| serine | 1.4324 | 1.6486 | 0.5329 | 0.8531 |
| SID | 1.5158 | 1.6845 | 0.2647 | 1.2702 |
| sn-glycerol-3-phosphate | 1.6803 | 1.5842 | 0.0672 | 1.6010 |
| succinate/Methylmalonic acid | 1.4785 | 1.3367 | 0.4258 | 1.3332 |
| thiamine | 0.2543 | 0.2549 | 2.1357 | 0.2193 |
| Thiamine pyrophosphate | 1.7385 | 1.4958 | 0.4245 | 0.7729 |
| threonine/homoserine | 1.4930 | 1.7912 | 0.3574 | 1.0010 |
| thymidine | 0.5915 | 0.5207 | 1.8238 | 0.2403 |
| tryptophan | 1.2742 | 1.6502 | 0.4865 | 1.1027 |
| tyrosine | 1.3195 | 1.7882 | 0.3374 | 1.2174 |
| UDP | 0.7805 | 0.7663 | 1.3837 | 0.7816 |
| UDP-D-glucose | 0.9563 | 1.1017 | 0.9951 | 0.9505 |
| UDP-D-glucuronate | 0.0300 | 0.0317 | 2.6600 | 0.0333 |
| UDP-N-acetyl-glucosamine | 1.2449 | 0.5331 | 1.0170 | 1.1922 |
| UMP | 1.6785 | 1.9300 | 0.0461 | 1.2992 |
| uridine | 1.5791 | 1.3319 | 0.5933 | 0.9023 |
| UTP | 0.5718 | 0.5834 | 1.6527 | 0.7026 |
| valine | 1.1286 | 1.5479 | 0.7172 | 0.8891 |
| VD | 0.3054 | 0.2913 | 2.1089 | 0.1855 |
| xanthosine-5-phosphate | 0.1084 | 0.1536 | 3.0684 | 0.1525 |
Factors:
| F1 | Genotype:II3 gna1-3xHA-loxP | Treatment:DMSO |
| F2 | Genotype:II3 gna1-3xHA-loxP | Treatment:Rapamycin |
| F3 | Genotype:NA | Treatment:NA |
| F4 | Genotype:WT | Treatment:None |
