Data for (Study ST003914)
(Analysis AN006427)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 | F19 | F20 | F21 | F22 | F23 | F24 | F25 | F26 | F27 | F28 | F29 | F30 | F31 | F32 | F33 | F34 | F35 | F36 | F37 | F38 | F39 | F40 | F41 | F42 | F43 | F44 | F45 | F46 | F47 | F48 | F49 | F50 | F51 | F52 | F53 | F54 | F55 | F56 | F57 | F58 | F59 | F60 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| glucose 1-phosphate M+0 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0343 | 0.9657 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose 1-phosphate M+6 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.0266 | 1.9734 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+0 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+1 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+2 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+3 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+4 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+5 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| glucose M+6 | 1.0000 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| ribose-5-phosphate M+0 | NA | 0.0390 | 0.0551 | 0.0276 | 0.0456 | 0.0207 | 0.0236 | 0.0308 | 0.0439 | 2.0940 | 0.2090 | 1.1536 | 0.5373 | 0.3586 | 0.2532 | 0.0835 | 1.1509 | 0.2029 | 1.5316 | 0.3176 | 3.1629 | 2.1816 | NA | NA | 0.2626 | 1.9998 | 1.0572 | 0.4282 | NA | NA | 2.7305 | 0.6405 | 0.2960 | 4.3844 | 0.4841 | 3.6850 | 8.2613 | 0.4582 | 0.0264 | 0.0315 | 0.0560 | 0.0292 | 0.0484 | 0.0415 | 0.0587 | 1.2256 | 0.5929 | 1.7511 | 0.1619 | 0.6574 | 3.7440 | 0.6172 | 0.0887 | 0.0239 | 4.1146 | 1.2169 | 0.4818 | 0.4745 | 0.4121 | 0.5781 |
| ribose-5-phosphate M+5 | NA | 0.4606 | 0.5831 | 0.0519 | 0.0727 | 0.0291 | 0.0468 | 0.3938 | 0.5273 | 0.3619 | 0.0269 | 0.4486 | 0.2587 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.0774 | 1.3383 | 0.1282 | 0.1859 | NA | NA | NA | NA | NA | 9.5286 | 0.0231 | 3.4693 | 7.8397 | 0.0676 | 0.1588 | 0.4033 | 0.6867 | 0.0554 | 0.0774 | 0.4910 | 0.6087 | NA | NA | NA | 0.0697 | 0.6301 | 4.8391 | 0.0221 | NA | NA | 3.5024 | 0.3007 | 0.8171 | 0.0047 | 0.0083 | 0.0115 |
| sedoheptulose 7-phosphate | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.7161 | 0.6678 | 0.0437 | 1.1894 | 0.1399 | 0.7010 | 0.4535 | 7.8588 | 1.1246 | NA | NA | NA | NA | NA | NA | NA | NA | 0.9533 | 0.2738 | 0.3275 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 0.3593 | 0.2146 | 0.7028 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| uridine diphosphate glucose M+6 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | 1.0820 | 0.9180 | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
Factors:
| F1 | Experiment title:Experiment 10 | Genotype:Wild Type | Treatment condition:Cellular glycogen isolation | Cell type:CD8 T cell |
| F2 | Experiment title:Experiment 11 | Genotype:Wild Type | Treatment condition:control treatment and treat 13C glucose for 2h | Cell type:CD8 T cell |
| F3 | Experiment title:Experiment 11 | Genotype:Wild Type | Treatment condition:control treatment and treat 13C glucose for 4h | Cell type:CD8 T cell |
| F4 | Experiment title:Experiment 11 | Genotype:Wild Type | Treatment condition:GPI treatment and treat 13C glucose for 2h | Cell type:CD8 T cell |
| F5 | Experiment title:Experiment 11 | Genotype:Wild Type | Treatment condition:GPI treatment and treat 13C glucose for 4h | Cell type:CD8 T cell |
| F6 | Experiment title:Experiment 12 | Genotype:sgGys1 | Treatment condition:GYS1 sgRNA and and treat 13C glucose for 2h | Cell type:CD8 T cell |
| F7 | Experiment title:Experiment 12 | Genotype:sgGys1 | Treatment condition:GYS1 sgRNA and and treat 13C glucose for 4h | Cell type:CD8 T cell |
| F8 | Experiment title:Experiment 12 | Genotype:Wild Type | Treatment condition:control sgRNA and and treat 13C glucose for 2h | Cell type:CD8 T cell |
| F9 | Experiment title:Experiment 12 | Genotype:Wild Type | Treatment condition:control sgRNA and and treat 13C glucose for 4h | Cell type:CD8 T cell |
| F10 | Experiment title:Experiment 13 | Genotype:sgGys1 | Treatment condition:SG gys1 sgRNA | Cell type:BMDM |
| F11 | Experiment title:Experiment 13 | Genotype:sgGys1 | Treatment condition:SG gys1 sgRNA | Cell type:CD8 T cell |
| F12 | Experiment title:Experiment 13 | Genotype:Wild Type | Treatment condition:control sgRNA | Cell type:BMDM |
| F13 | Experiment title:Experiment 13 | Genotype:Wild Type | Treatment condition:control sgRNA | Cell type:CD8 T cell |
| F14 | Experiment title:Experiment 14 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F15 | Experiment title:Experiment 14 | Genotype:Wild Type | Treatment condition:GPI and G1P treatment | Cell type:CD8 T cell |
| F16 | Experiment title:Experiment 14 | Genotype:Wild Type | Treatment condition:GPI treatment | Cell type:CD8 T cell |
| F17 | Experiment title:Experiment 15 | Genotype:sgPGM1 | Treatment condition:PGM1 sgRNA and G6P LNP treatment | Cell type:BMDM |
| F18 | Experiment title:Experiment 15 | Genotype:sgPGM1 | Treatment condition:PGM1 sgRNA and G6P LNP treatment | Cell type:CD8 T cell |
| F19 | Experiment title:Experiment 15 | Genotype:sgPGM1 | Treatment condition:PGM1 sgRNA | Cell type:BMDM |
| F20 | Experiment title:Experiment 15 | Genotype:sgPGM1 | Treatment condition:PGM1 sgRNA | Cell type:CD8 T cell |
| F21 | Experiment title:Experiment 15 | Genotype:Wild Type | Treatment condition:control sgRNA | Cell type:BMDM |
| F22 | Experiment title:Experiment 15 | Genotype:Wild Type | Treatment condition:control sgRNA | Cell type:CD8 T cell |
| F23 | Experiment title:Experiment 16 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F24 | Experiment title:Experiment 16 | Genotype:Wild Type | Treatment condition:GPI treatment | Cell type:CD8 T cell |
| F25 | Experiment title:Experiment 17 | Genotype:Wild Type | Treatment condition:control NP | Cell type:CD8 T cell |
| F26 | Experiment title:Experiment 17 | Genotype:Wild Type | Treatment condition:G1P LNP treatment | Cell type:CD8 T cell |
| F27 | Experiment title:Experiment 18 | Genotype:D421A | Treatment condition:G6PD D421 KI | Cell type:CD8 T cell |
| F28 | Experiment title:Experiment 18 | Genotype:Wild Type | Treatment condition:G6PD WT KI | Cell type:CD8 T cell |
| F29 | Experiment title:Experiment 19 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F30 | Experiment title:Experiment 19 | Genotype:Wild Type | Treatment condition:GPI treatment | Cell type:CD8 T cell |
| F31 | Experiment title:Experiment 1 | Genotype:Wild Type | Treatment condition:2-deoxy-D-glucose (2-DG, 1 mM) | Cell type:CD8 T cell |
| F32 | Experiment title:Experiment 1 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F33 | Experiment title:Experiment 1 | Genotype:Wild Type | Treatment condition:HK inhibitor Lonidamine (50 μM) | Cell type:CD8 T cell |
| F34 | Experiment title:Experiment 20 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F35 | Experiment title:Experiment 20 | Genotype:Wild Type | Treatment condition:GPI treatment | Cell type:CD8 T cell |
| F36 | Experiment title:Experiment 21 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:BMDM |
| F37 | Experiment title:Experiment 21 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F38 | Experiment title:Experiment 21 | Genotype:Wild Type | Treatment condition:HEX treatment | Cell type:CD8 T cell |
| F39 | Experiment title:Experiment 2 | Genotype:Wild Type | Treatment condition:13C_glucose treatment for 0h | Cell type:CD8 T cell |
| F40 | Experiment title:Experiment 2 | Genotype:Wild Type | Treatment condition:13C_glucose treatment for 2h | Cell type:CD8 T cell |
| F41 | Experiment title:Experiment 2 | Genotype:Wild Type | Treatment condition:13C_glucose treatment for 4h | Cell type:CD8 T cell |
| F42 | Experiment title:Experiment 3 | Genotype:sgPygb | Treatment condition:13C_glucose treatment for 2h | Cell type:CD8 T cell |
| F43 | Experiment title:Experiment 3 | Genotype:sgPygb | Treatment condition:13C_glucose treatment for 4h | Cell type:CD8 T cell |
| F44 | Experiment title:Experiment 3 | Genotype:Wild Type | Treatment condition:13C_glucose treatment for 2h | Cell type:CD8 T cell |
| F45 | Experiment title:Experiment 3 | Genotype:Wild Type | Treatment condition:13C_glucose treatment for 4h | Cell type:CD8 T cell |
| F46 | Experiment title:Experiment 4 | Genotype:sgPygb | Treatment condition:PYGB sgRNA and G1P LNP treatment | Cell type:CD8 T cell |
| F47 | Experiment title:Experiment 4 | Genotype:sgPygb | Treatment condition:PYGB sgRNA | Cell type:CD8 T cell |
| F48 | Experiment title:Experiment 4 | Genotype:Wild Type | Treatment condition:control sgRNA | Cell type:CD8 T cell |
| F49 | Experiment title:Experiment 5 | Genotype:Wild Type | Treatment condition:control NP | Cell type:CD8 T cell |
| F50 | Experiment title:Experiment 5 | Genotype:Wild Type | Treatment condition:G1P LNP treatment | Cell type:CD8 T cell |
| F51 | Experiment title:Experiment 6 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F52 | Experiment title:Experiment 6 | Genotype:Wild Type | Treatment condition:HEX treatment | Cell type:CD8 T cell |
| F53 | Experiment title:Experiment 7 | Genotype:Wild Type | Treatment condition:Cellular glycogen isolation | Cell type:CD8 T cell |
| F54 | Experiment title:Experiment 7 | Genotype:Wild Type | Treatment condition:Cytoplasmic separation | Cell type:CD8 T cell |
| F55 | Experiment title:Experiment 8 | Genotype:Wild Type | Treatment condition:control treatment | Cell type:CD8 T cell |
| F56 | Experiment title:Experiment 8 | Genotype:Wild Type | Treatment condition:GPI treatment | Cell type:CD8 T cell |
| F57 | Experiment title:Experiment 9 | Genotype:Wild Type | Treatment condition:control NP | Cell type:CD8 T cell |
| F58 | Experiment title:Experiment 9 | Genotype:Wild Type | Treatment condition:control NP | Cell type:tumor-associated Macrophages |
| F59 | Experiment title:Experiment 9 | Genotype:Wild Type | Treatment condition:G1P LNP treatment | Cell type:CD8 T cell |
| F60 | Experiment title:Experiment 9 | Genotype:Wild Type | Treatment condition:G1P LNP treatment | Cell type:tumor-associated Macrophages |
