Data for (Study ST003930)
(Analysis AN006453)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 1-methyladenosine | 0.0061 | 3.6374 | 0.2611 |
| 1-methylguanine | 1.5683 | 0.2588 | 0.8970 |
| 1-methylguanosine | 0.3637 | 3.5290 | 0.2658 |
| 1-methylhistamine | 0.3816 | 0.1313 | 1.9497 |
| 1-methylnicotinamide | 1.1839 | 2.6881 | 0.0027 |
| 2-aminoisobutyric acid | 0.9076 | 0.0576 | 1.1556 |
| 2-deoxyadenosine | 0.0823 | 0.0381 | 2.2457 |
| 2-deoxycytidine | 0.8800 | 0.8002 | 1.1999 |
| 3-methoxytyramine | 0.2303 | 0.0294 | 1.8032 |
| 3-methylhistidine | 0.5451 | 0.2632 | 1.7475 |
| 3-methylxanthine | 2.3997 | 0.0407 | 0.2508 |
| 4-acetamidobutanoate | 1.1609 | 0.2764 | 1.2278 |
| 4-aminohippuric acid | 0.7197 | 0.5921 | 1.8284 |
| 4-guanidinobutanoic acid | 1.6024 | 1.1237 | 0.4362 |
| 4-pyridoxate | 0.7664 | 0.4196 | 1.4849 |
| 5-hydroxytryptophan | 1.4508 | 1.6259 | 0.3113 |
| 5-methylcytidine | 0.5297 | 2.5098 | 0.6370 |
| 5-methylcytosine | 2.1656 | 0.4503 | 0.3036 |
| 7-methylguanine | 1.3908 | 1.2351 | 0.5568 |
| acetylcholine | 0.9957 | 0.7957 | 1.1057 |
| acetyl-galactosamine | 0.6670 | 0.2295 | 1.6628 |
| acisoga | 1.2493 | 1.2923 | 0.6461 |
| adenosine | 0.1836 | 0.0580 | 2.1513 |
| ADMA | 1.5710 | 0.8378 | 0.6052 |
| agmatine | 1.0302 | 1.1957 | 0.8770 |
| ala-ala | 0.1922 | 0.1922 | 2.0771 |
| alanine | 0.6169 | 0.1988 | 1.7199 |
| allantoin | 1.6502 | 1.2287 | 0.0156 |
| allopurinol riboside | 0.0996 | 0.2319 | 2.1344 |
| alpha-glycerophosphocholine | 1.8362 | 0.3418 | 0.6323 |
| anserine | 0.3713 | 0.4236 | 1.8121 |
| anthranilic acid | 0.3342 | 0.0510 | 2.0293 |
| arginine | 1.5437 | 0.7185 | 0.6876 |
| asparagine | 1.2269 | 1.9708 | 0.3255 |
| aspartate | 0.7473 | 0.4349 | 1.4931 |
| atenolol | 0.1874 | 0.2169 | 2.0687 |
| beta-guanidinopropionic acid | 0.4329 | 0.3840 | 1.7806 |
| betaine | 1.2747 | 0.8686 | 0.8368 |
| betalanine | 0.3647 | 0.1125 | 1.9731 |
| bilirubin | 0.2097 | 0.2868 | 2.0152 |
| biliverdin | 1.2151 | 0.8533 | 0.8941 |
| biopterin | 1.4507 | 1.9788 | 0.1350 |
| biotin | 0.9468 | 0.2187 | 1.4350 |
| butyrobetaine | 0.0263 | 0.0302 | 2.2963 |
| C10:2 carnitine | 0.7801 | 1.8638 | 0.0053 |
| C10 carnitine | 1.5561 | 1.2172 | 0.0194 |
| C12:1 carnitine | 1.6216 | 1.2543 | 0.0323 |
| C12 carnitine | 1.4442 | 1.8523 | 0.0444 |
| C14:1 carnitine | 1.7142 | 1.5475 | 0.0521 |
| C14:2 carnitine | 1.7701 | 1.5326 | 0.0093 |
| C14 carnitine | 1.6370 | 1.6202 | 0.0826 |
| C16 carnitine | 1.5565 | 1.4814 | 0.2956 |
| C16-OH carnitine | 2.0081 | 1.0348 | 0.1425 |
| C18:1 carnitine | 1.5630 | 0.9113 | 0.5752 |
| C18:1-OH carnitine | 1.7306 | 1.3992 | 0.1915 |
| C18:2 carnitine | 2.0395 | 1.0349 | 0.1162 |
| C18 carnitine | 1.3312 | 1.0220 | 0.7130 |
| C20:4 carnitine | 1.0187 | 2.0261 | 0.3656 |
| C20 carnitine | 0.4716 | 0.4994 | 1.6489 |
| C2 carnitine | 1.1156 | 2.1654 | 0.3210 |
| C34:1 DAG or TAG Na adduct | 0.8085 | 1.4100 | 0.9545 |
| C34:1 DAG or TAG NH4 adduct | 0.6408 | 0.5602 | 1.5193 |
| C34:2 DAG or TAG Na adduct | 1.0875 | 1.4876 | 0.6833 |
| C3 carnitine | 1.8819 | 1.1636 | 0.1832 |
| C3-DC-CH3 carnitine | 1.1198 | 1.1747 | 0.8128 |
| C4 carnitine | 2.1453 | 0.6737 | 0.2087 |
| C4-OH carnitine | 2.1954 | 0.4407 | 0.2835 |
| C5 carnitine | 2.3583 | 0.6611 | 0.0375 |
| C5-DC carnitine | 0.9083 | 1.6512 | 0.7508 |
| C6 carnitine | 1.6467 | 1.5283 | 0.0364 |
| C7 carnitine | 0.9852 | 0.2786 | 1.3730 |
| C8 carnitine | 1.4638 | 1.3646 | 0.0249 |
| cadaverine | 1.9324 | 0.6398 | 0.4031 |
| carnitine | 1.3490 | 1.3800 | 0.5192 |
| carnosine | 0.4900 | 1.2061 | 1.3219 |
| Cer(d18:1/16:0) | 0.6334 | 1.0421 | 1.2844 |
| Cer(d18:1/24:1) | 0.0810 | 0.1356 | 2.1260 |
| choline | 1.7561 | 1.0626 | 0.3386 |
| citrulline | 0.0231 | 0.0226 | 2.3028 |
| creatine | 1.2798 | 1.7584 | 0.3876 |
| creatinine | 1.1546 | 1.4957 | 0.6233 |
| cyclohexylamine | 0.8885 | 0.9943 | 1.0957 |
| cytidine | 0.5294 | 1.9805 | 0.9019 |
| cytosine | 0.5148 | 2.0506 | 0.8791 |
| diacetylspermine | 2.2580 | 0.0649 | 0.4192 |
| DMGV | 1.6155 | 1.1211 | 0.4265 |
| ectoine | 0.0551 | 0.0315 | 2.2716 |
| GABA | 1.0622 | 0.3960 | 1.2502 |
| glucosamine | 0.3396 | 3.3645 | 0.3681 |
| glutamate | 0.6435 | 0.4534 | 1.5704 |
| glutamine | 1.0979 | 1.5860 | 0.6254 |
| glycine | 0.8408 | 0.3340 | 1.4657 |
| glycocholate | 1.5763 | 1.6245 | 0.2075 |
| guanidinoacetic acid | 0.2144 | 0.3373 | 1.9860 |
| guanidinosuccinic acid | 0.9712 | 0.2764 | 1.3858 |
| guanosine | 0.0033 | 2.0643 | 1.2984 |
| histamine | 0.4858 | 0.1966 | 1.8302 |
| histidine | 0.5181 | 0.7129 | 1.5451 |
| histidinol | 1.1336 | 1.8643 | 0.4565 |
| homoarginine | 1.6996 | 0.5067 | 0.6636 |
| homocitrulline | 1.1290 | 0.9281 | 0.9285 |
| hydroxyproline | 0.5096 | 0.7117 | 1.5528 |
| hypotaurine | 0.1451 | 0.2231 | 1.8224 |
| imidazoleacetic acid | 0.7721 | 0.5996 | 1.3901 |
| imidazole propionate | 0.0083 | 0.0037 | 2.3246 |
| indoleacetic acid | 0.9183 | 0.0740 | 1.4539 |
| indolin-2-one | NA | NA | 1.0000 |
| inosine | 0.0063 | 0.5563 | 2.0499 |
| isoleucine | 0.5779 | 0.3617 | 1.6709 |
| kynurenic acid | 1.3502 | 0.5406 | 0.9379 |
| L-alpha-glutamyl-L-lysine | 1.6386 | 0.9071 | 0.5143 |
| leucine | 0.6263 | 0.3843 | 1.6193 |
| leu-gly | 0.3459 | 0.3445 | 1.8728 |
| linoleoyl ethanolamide | 1.4878 | 0.4380 | 0.8745 |
| LPC(16:0) | 1.2823 | 2.0028 | 0.2633 |
| LPC(16:1) | 1.0823 | 2.6989 | 0.0820 |
| LPC(18:0) | 0.9836 | 2.5795 | 0.2239 |
| LPC(18:1) | 1.4046 | 1.7443 | 0.2907 |
| LPC(18:2) | 1.5153 | 1.6846 | 0.2283 |
| LPC(18:3) | 1.4741 | 1.8771 | 0.1664 |
| LPC(20:1) | 1.1263 | 1.7042 | 0.5426 |
| LPC(20:4) | 1.1778 | 2.5947 | 0.0545 |
| LPC(20:5) | 1.6851 | 1.7259 | 0.0661 |
| LPC(24:0) | 0.7062 | 1.2496 | 1.1200 |
| LPC(P-16:0)/LPC(O-16:1) | 1.0710 | 2.3019 | 0.2899 |
| LPC(P-18:0)/LPC(O-18:1)_a | 1.2271 | 1.3685 | 0.4397 |
| LPC(P-18:0)/LPC(O-18:1)_b | 1.1141 | 1.0753 | 0.8230 |
| LPE(16:0) | 1.4336 | 1.1863 | 0.5455 |
| LPE(18:0) | 0.7219 | 2.9094 | 0.2771 |
| LPE(18:1) | 0.9206 | 1.8549 | 0.6387 |
| LPE(18:2) | 1.0530 | 1.9753 | 0.4682 |
| LPE(20:0) | 1.1929 | 2.1216 | 0.2784 |
| lysine | 0.5630 | 0.2721 | 1.7281 |
| methionine | 0.4465 | 0.1859 | 1.8683 |
| methionine sulfoxide | 0.5753 | 0.6342 | 1.5368 |
| methylguanidine | 0.6835 | 0.7425 | 1.3925 |
| methylimidazoleacetic acid | 0.1596 | 0.2481 | 2.0763 |
| methylthioadenosine | 0.0778 | 2.2336 | 1.1517 |
| myristoleic acid | 1.1504 | 1.0398 | 0.8548 |
| N1-acetylspermidine | 0.9415 | 0.6230 | 1.2373 |
| N1-methyl-2-pyridone-5-carboxamide | 1.3752 | 1.4007 | 0.4870 |
| N2,N2-dimethylguanosine | 0.0011 | 4.6495 | 0.0077 |
| N4-acetylcytidine | 0.2525 | 0.9142 | 1.6658 |
| N6-acetyllysine | 0.6411 | 0.5503 | 1.5239 |
| N6-methyllysine | 0.8423 | 1.2652 | 0.9989 |
| N6,N6-dimethyllysine | 1.0384 | 0.5233 | 1.2064 |
| N6,N6,N6-trimethyllysine | 1.4159 | 0.7636 | 0.7716 |
| N-acetylalanine | 1.8500 | 0.7172 | 0.4331 |
| N-acetylaspartic acid | 0.1534 | 0.0132 | 2.1989 |
| N-acetylglutamine | 1.3313 | 0.2070 | 1.1204 |
| N-acetylhistamine | 0.8255 | 0.0030 | 1.6440 |
| N-acetylhistidine | 0.0771 | 0.0634 | 2.2374 |
| N-acetylleucine | 0.8535 | 0.4161 | 1.4141 |
| N-acetylornithine | 0.1573 | 0.0814 | 2.1615 |
| N-acetylputrescine | 1.7351 | 0.2329 | 0.7710 |
| N-acetyltryptophan | 1.3008 | 0.5201 | 0.9893 |
| N-alpha-acetylarginine | 1.1626 | 1.6795 | 0.5247 |
| N-carbamoyletalanine | 0.4747 | 0.2581 | 1.8087 |
| niacinamide | 0.3505 | 3.2259 | 0.4283 |
| nicotinate | 0.6488 | 0.0103 | 1.7875 |
| N-lauroylglycine | 1.0658 | 1.0094 | 0.9405 |
| N-methylproline | 0.0178 | 0.0110 | 2.3130 |
| N-methylserotonin | 0.5410 | 0.2123 | 1.7763 |
| NMMA | 1.4205 | 0.7021 | 0.7985 |
| nor-psi-tropine | 1.4562 | 0.3138 | 0.9630 |
| O-methyladenosine | 0.0042 | 0.0062 | 1.7458 |
| ornithine | 0.1384 | 0.0752 | 2.1804 |
| pantothenate | 1.0811 | 0.1006 | 1.3822 |
| pantothenol | 1.7145 | 0.4178 | 0.6956 |
| PC(30:0) | 0.7821 | 1.9045 | 0.7293 |
| PC(32:2) | 0.9188 | 1.3374 | 0.8990 |
| PC(34:3) | 0.8531 | 1.3273 | 0.9588 |
| PC(36:2) | 0.8095 | 1.4530 | 0.9323 |
| PC(P-34:2)/PC(O-34:3) | 0.6771 | 1.8291 | 0.8061 |
| PC(P-36:4)/PC(O-36:5) | 0.4363 | 2.1069 | 0.9163 |
| PE(34:0) | 0.8123 | 1.3718 | 0.9705 |
| PE(34:2) | 2.4016 | 0.1241 | 0.2699 |
| PE(36:2) | 0.6592 | 1.9597 | 0.8042 |
| PE(36:4) | 1.1684 | 0.9276 | 0.8959 |
| PE(38:4) | 0.2596 | 3.3896 | 0.3066 |
| PE(P-34:1)/PE(O-34:2) | 0.9138 | 1.4889 | 0.8274 |
| PE(P-34:2)/PE(O-34:3) | 1.8597 | 0.8221 | 0.3726 |
| PE(P-36:2)/PE(O-36:3) | 0.8369 | 1.8390 | 0.7165 |
| PE(P-36:4)/PE(O-36:5) | 0.5578 | 2.3159 | 0.7105 |
| PE(P-38:4)/PE(O-38:5) | 0.6757 | 2.0576 | 0.7414 |
| PE(P-38:5)/PE(O-38:6) | 0.4812 | 2.2906 | 0.7870 |
| phenylalanine | 0.5690 | 0.3045 | 1.7069 |
| phenylalanine-d8 | 1.0035 | 0.9772 | 1.0085 |
| phosphocholine | 0.1748 | 0.0238 | 2.1758 |
| phytosphingosine | 1.4179 | 1.4433 | 0.4301 |
| pipecolic acid | 0.7222 | 0.5434 | 1.4598 |
| piperine | 0.6955 | 0.6741 | 1.4167 |
| pro-gly | 1.6388 | 1.6292 | 0.1531 |
| proline | 1.8129 | 0.3667 | 0.6392 |
| prolineetaine | 0.8691 | 0.3473 | 1.4354 |
| pseudouridine | 0.1748 | 0.3779 | 1.9987 |
| pterin | 0.0434 | 0.0086 | 2.1276 |
| putrescine | 0.8361 | 0.3030 | 1.4851 |
| pyridoxamine | 0.6668 | 0.2645 | 1.6455 |
| pyridoxine | 0.9343 | 0.1349 | 1.4873 |
| pyroglutamic acid | 2.1571 | 0.3103 | 0.3806 |
| salsolinol | 0.8459 | 0.6182 | 1.3194 |
| SDMA | 0.9721 | 0.5138 | 1.2663 |
| serine | 0.7471 | 0.7232 | 1.3492 |
| serotonin | 0.6703 | 0.3502 | 1.5996 |
| SM(d18:1/16:0) | 0.6315 | 1.1964 | 1.2088 |
| S-methyl-L-cysteine-S-oxide | 0.7426 | 0.9065 | 1.2612 |
| sphinganine | 0.6372 | 0.5962 | 1.5042 |
| sphingosine | 2.1284 | 0.2647 | 0.4273 |
| stercobilin | NA | 0.0014 | 1.0832 |
| taurine | 0.3675 | 0.2223 | 1.9160 |
| thiamine | 0.7607 | 0.7194 | 1.3397 |
| threonine | 0.4980 | 1.5389 | 1.1489 |
| trigonelline | 0.4382 | 0.2826 | 1.8269 |
| trimethylamine-N-oxide | 0.0207 | 0.3141 | 1.6412 |
| trimethylbenzene | 0.8513 | 0.7282 | 1.2598 |
| tryptamine | 0.5038 | 0.2146 | 1.8062 |
| tryptophan | 1.1105 | 0.5163 | 1.1498 |
| tyramine | 0.4985 | 0.1871 | 1.8243 |
| tyrosine | 0.5432 | 0.2982 | 1.7316 |
| urobilinogen | 2.0260 | 0.0001 | 0.3950 |
| urocanic acid | 0.2065 | 0.1423 | 2.0901 |
| valine | 0.4252 | 0.2852 | 1.8363 |
| valine-d8 | 0.9749 | 1.0178 | 1.0120 |
| xanthine | 0.1672 | 0.1922 | 2.0979 |
| xanthosine | 0.0634 | 0.3458 | 2.1076 |
Factors:
| F1 | Sample source:Fecal Samples | Type:Altered Schaedler Flora (ASF) |
| F2 | Sample source:Fecal Samples | Type:germ-free (GF) |
| F3 | Sample source:Fecal Samples | Type:specified-pathogen free (SPF) |