Data for (Study ST003959)
(Analysis AN006507)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 | F12 | F13 | F14 | F15 | F16 | F17 | F18 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1,2,3-Trihydroxybenzene_HMDB0013674 | 1.4091 | 1.3633 | 1.3701 | 0.9592 | 0.7627 | 0.8765 | 0.9007 | 1.0231 | 1.0458 | 0.2954 | 0.9335 | 0.7450 | 1.0577 | 1.4590 | 1.4806 | 0.5348 | 0.9140 | 0.8696 |
| 1-Hexadecanol_HMDB0003424 | 0.7537 | 0.7619 | 0.5779 | 0.5460 | 0.5142 | 1.4474 | 0.4550 | 0.4425 | 0.3665 | 1.4246 | 1.3527 | 0.4005 | 1.8887 | 1.6050 | 1.2189 | 1.0447 | 1.0700 | 2.1296 |
| 2,3-Dihydroxybutanedioic acid_HMDB0059916 | 0.8905 | 0.8304 | 0.7152 | 0.4058 | 0.5992 | 0.6093 | 0.9751 | 1.2441 | 1.2320 | 0.4811 | 1.4419 | 1.1027 | 1.3726 | 1.1982 | 0.7483 | 1.2462 | 1.5803 | 1.3269 |
| 2-Aminoheptanedioic acid_HMDB0034252 | 0.3117 | 0.3080 | 0.2732 | 0.3138 | 0.3037 | 0.3109 | 0.1921 | 0.1842 | 0.2079 | 0.2511 | 0.3289 | 0.2213 | 2.2345 | 2.3813 | 2.5681 | 2.3373 | 2.4922 | 2.7797 |
| 2-Aminooctanoic acid_HMDB0000991 | 0.1452 | 0.1546 | 0.1414 | 0.1374 | 0.1548 | 0.1283 | 0.1954 | 0.1690 | 0.1744 | 0.1751 | 0.1708 | 0.1736 | 2.4480 | 2.6776 | 2.9661 | 2.5556 | 2.4213 | 3.0115 |
| 2-Deoxy-D-ribose_HMDB0245099 | 0.8600 | 0.7010 | 1.2446 | 0.9523 | 1.1118 | 1.2841 | 0.6880 | 0.4443 | 0.4665 | 0.8726 | 0.6210 | 0.5089 | 1.4094 | 0.9521 | 1.5473 | 1.6502 | 1.2834 | 1.4024 |
| 2-Deoxyglucose_HMDB0062477 | 1.1256 | 1.3023 | 1.1721 | 1.2344 | 1.2001 | 1.0927 | 0.7264 | 0.6419 | 0.7286 | 0.6866 | 0.6910 | 0.7059 | 1.0659 | 1.0214 | 1.1425 | 1.1343 | 1.1399 | 1.1884 |
| (2E)-3-(4-hydroxy-3-methoxyphenyl)prop-2-enal_HMDB0141782 | 0.6817 | 1.1148 | 0.6780 | 0.9337 | 0.7858 | 1.0182 | 0.5513 | 0.4289 | 0.8501 | 0.6466 | 0.6610 | 0.6457 | 1.2634 | 1.1279 | 1.8901 | 1.4363 | 1.5670 | 1.7195 |
| 2-Hydroxy-3-methylbutyric acid_HMDB0000407 | 0.9697 | 1.0040 | 0.9421 | 0.9053 | 1.0593 | 0.9569 | 1.0482 | 0.7841 | 1.0149 | 1.0895 | 1.1378 | 0.9093 | 0.8523 | 1.0506 | 1.0179 | 1.0138 | 1.1286 | 1.1158 |
| 2-Hydroxybutyric acid_HMDB0000008 | 0.8733 | 0.9309 | 0.9268 | 0.9154 | 0.9051 | 0.8639 | 1.0436 | 0.9815 | 1.0036 | 0.9871 | 0.9518 | 0.9588 | 1.0384 | 1.0505 | 1.1468 | 1.0852 | 1.1072 | 1.2303 |
| 2-Hydroxyglutaric acid_HMDB0000694 | 0.1060 | 0.1188 | 0.1025 | 0.1061 | 0.1138 | 0.1067 | 3.0262 | 2.4755 | 2.3880 | 2.8758 | 2.6136 | 2.4627 | 0.2076 | 0.2538 | 0.2762 | 0.2337 | 0.2569 | 0.2762 |
| 2-Phosphoglyceric acid_HMDB0000362 | 1.2511 | 1.2990 | 1.3962 | 1.2007 | 1.3866 | 1.2483 | 0.4617 | 0.4778 | 0.4241 | 0.4090 | 0.3146 | 0.5248 | 1.2572 | 1.2076 | 1.2411 | 1.3391 | 1.4525 | 1.1086 |
| 3-Aminoisobutanoic acid_HMDB0003911 | 0.9522 | 0.9443 | 1.0044 | 1.0152 | 1.1142 | 0.9454 | 1.1764 | 0.9658 | 1.0115 | 0.9821 | 1.0011 | 0.9542 | 0.9013 | 0.8566 | 1.0353 | 1.0353 | 0.9837 | 1.1208 |
| 3-Dehydroshikimic acid | 0.8196 | 0.7391 | 0.7787 | 0.7950 | 0.8636 | 0.7479 | 0.7584 | 0.5756 | 0.6327 | 0.6049 | 0.5428 | 0.4922 | 1.6710 | 1.2575 | 1.6709 | 1.6639 | 1.7346 | 1.6514 |
| 3-Hydroxybutyric acid_HMDB0000357 | 1.1366 | 1.0618 | 0.8354 | 0.8209 | 0.9817 | 0.7800 | 0.9207 | 1.0010 | 0.9487 | 0.9113 | 0.9073 | 0.8643 | 0.9820 | 1.2530 | 1.3394 | 0.9942 | 1.0446 | 1.2169 |
| 3-Hydroxyglutaric acid_HMDB0000428 | 0.1127 | 0.1283 | 0.1135 | 0.1225 | 0.1261 | 0.1421 | 2.8828 | 2.4009 | 2.2553 | 2.8779 | 2.6537 | 2.4432 | 0.2735 | 0.2623 | 0.2822 | 0.2929 | 0.3034 | 0.3267 |
| 3-Hydroxyisovaleric acid_HMDB0000754 | 1.0205 | 0.9905 | 0.8739 | 0.8664 | 0.9360 | 0.9573 | 0.5834 | 0.5422 | 0.6567 | 0.6718 | 0.6645 | 0.5827 | 1.2517 | 1.5796 | 1.5808 | 1.3216 | 1.4074 | 1.5131 |
| 3-Hydroxymethylglutaric acid_HMDB0000355 | 0.4911 | 0.1553 | 0.2852 | 0.2785 | 0.5169 | 0.4855 | 0.8506 | 0.6639 | 1.0133 | 0.8520 | 0.8995 | 0.8192 | 1.9289 | 1.5550 | 2.0713 | 1.5868 | 1.9659 | 1.5809 |
| 3-Methyl-2-oxovaleric acid_HMDB0000491 | 0.7423 | 0.6496 | 0.6446 | 0.7599 | 0.7005 | 0.7053 | 1.5357 | 1.3221 | 1.4962 | 1.4799 | 1.3619 | 1.2689 | 0.8794 | 0.8376 | 0.9468 | 0.8432 | 0.8775 | 0.9485 |
| 3-Phosphoglyceric acid_HMDB0000807 | 1.5861 | 1.4460 | 1.4607 | 1.2114 | 1.2330 | 1.1096 | 0.4569 | 0.5093 | 0.5229 | 0.4740 | 0.4085 | 0.4439 | 1.3104 | 1.3240 | 0.9282 | 1.1577 | 1.3889 | 1.0286 |
| 3-Sulfinoalanine_HMDB0000996 | 0.6966 | 0.7778 | 0.3785 | 0.5734 | 0.4692 | 0.5328 | 0.3283 | 0.3486 | 0.4553 | 0.3690 | 0.3693 | 0.2474 | 2.5442 | 1.7013 | 1.7867 | 1.6126 | 1.5156 | 3.2932 |
| 4-Coumaric acid-2TMS | 0.8033 | 0.8441 | 0.9210 | 0.9357 | 0.8552 | 0.8845 | 0.6928 | 0.6603 | 0.6627 | 0.6640 | 0.5758 | 0.6825 | 1.3976 | 1.2640 | 1.4667 | 1.5099 | 1.5379 | 1.6419 |
| 4-Hydroxybenzoic acid_HMDB0000500 | 0.7448 | 0.9937 | 1.3550 | 0.8571 | 1.2083 | 0.6453 | 0.7406 | 0.5735 | 1.1161 | 1.3707 | 1.0402 | 0.7967 | 1.2994 | 0.8758 | 1.1299 | 0.9439 | 1.0316 | 1.2773 |
| 4-Hydroxyproline_HMDB0000725 | 0.8885 | 0.8898 | 0.9117 | 0.9578 | 0.9332 | 0.9578 | 0.4956 | 0.4093 | 0.4228 | 0.4772 | 0.4258 | 0.4322 | 1.5096 | 1.5153 | 1.7865 | 1.6874 | 1.5583 | 1.7413 |
| 5-Aminopentanoic acid_HMDB0003355 | 0.8918 | 0.9424 | 0.9257 | 0.9456 | 1.0083 | 0.9357 | 0.8983 | 0.7626 | 0.7684 | 0.8632 | 0.8098 | 0.7695 | 1.1443 | 1.2056 | 1.3234 | 1.2435 | 1.2033 | 1.3586 |
| Acetoacetic acid_HMDB0000060 | 0.9893 | 1.0069 | 1.0364 | 0.9946 | 1.0087 | 0.9168 | 1.0318 | 1.0452 | 1.0541 | 0.9905 | 0.9548 | 1.0167 | 0.9762 | 1.0180 | 1.0168 | 0.9589 | 1.0058 | 0.9783 |
| Adenine_HMDB0000034 | 0.7777 | 0.6897 | 0.9286 | 0.8540 | 0.8602 | 0.8177 | 1.5767 | 1.2245 | 1.5166 | 1.3963 | 1.2347 | 1.2365 | 0.9632 | 0.6690 | 0.8542 | 0.8583 | 0.7420 | 0.8001 |
| Adenosine_HMDB0000050 | 0.9390 | 0.8573 | 0.8619 | 0.7959 | 0.8040 | 1.1867 | 0.8964 | 0.8287 | 0.7519 | 0.7174 | 0.7003 | 0.7304 | 1.2809 | 1.2938 | 1.2895 | 1.1609 | 1.4565 | 1.4485 |
| Adipic acid_HMDB0000448 | 1.0891 | 0.8009 | 0.6423 | 0.5126 | 0.8035 | 1.4562 | 0.9053 | 0.7005 | 0.9919 | 1.4904 | 1.4822 | 0.7335 | 1.4840 | 1.0221 | 1.1076 | 0.6788 | 0.8501 | 1.2489 |
| Alanine_HMDB0000161 | 0.6564 | 0.6505 | 0.6957 | 0.7146 | 0.7037 | 0.7043 | 0.6691 | 0.5464 | 0.5789 | 0.6380 | 0.5754 | 0.5833 | 1.6143 | 1.6380 | 1.8061 | 1.7418 | 1.6756 | 1.8079 |
| Alpha-aminobutyric acid_HMDB0000650 | 0.9638 | 0.8558 | 0.9687 | 0.9963 | 0.9390 | 0.9613 | 0.4764 | 0.4260 | 0.4758 | 0.4434 | 0.4850 | 0.4747 | 1.4874 | 1.4587 | 1.6869 | 1.5827 | 1.5119 | 1.8061 |
| Alpha-Hydroxyisobutyric acid_HMDB0000729 | 1.0886 | 1.1990 | 0.8248 | 0.8136 | 0.7977 | 1.0474 | 0.8075 | 0.8809 | 1.1076 | 1.0200 | 0.9414 | 1.0280 | 1.0822 | 1.1981 | 1.1715 | 0.9562 | 0.9902 | 1.0451 |
| Alpha-ketoisovaleric acid_HMDB0000019 | 0.7396 | 0.5884 | 0.5973 | 0.7514 | 0.7331 | 0.7293 | 1.4544 | 1.2065 | 1.4949 | 1.4838 | 1.3820 | 1.2314 | 0.9205 | 0.8890 | 0.9548 | 0.9333 | 0.8650 | 1.0453 |
| Alpha-Lactose_HMDB0000186 | 0.8048 | 0.6954 | 0.6384 | 0.6981 | 0.7131 | 0.6432 | 1.5535 | 1.3745 | 1.8089 | 1.6190 | 1.4344 | 1.3804 | 0.8789 | 0.6041 | 0.7191 | 0.7862 | 0.7796 | 0.8681 |
| Arabinose_HMDB0029942 | 0.7641 | 0.7153 | 0.6785 | 0.7643 | 0.8223 | 0.7979 | 0.6850 | 0.4401 | 0.4644 | 0.6901 | 0.7112 | 0.4794 | 1.7044 | 1.2324 | 1.7632 | 1.7196 | 1.6085 | 1.9592 |
| Arabitol_HMDB0000568 | 1.3607 | 1.3384 | 1.1741 | 1.2167 | 1.2449 | 1.1975 | 0.5974 | 0.5022 | 0.6733 | 0.6154 | 0.6726 | 0.5221 | 1.1623 | 1.0826 | 1.1224 | 1.0502 | 1.0932 | 1.3740 |
| Arginine_HMDB0000517 | 1.0046 | 0.9409 | 0.7227 | 0.7260 | 0.6771 | 0.6636 | 0.6626 | 0.6025 | 0.7791 | 0.5900 | 0.6430 | 0.6002 | 1.6885 | 1.6381 | 1.6465 | 1.4080 | 1.4633 | 1.5433 |
| Asparagine_HMDB0000168 | 0.1167 | 0.1042 | 0.1469 | 0.1509 | 0.1557 | 0.1231 | 0.3653 | 0.2786 | 0.3013 | 0.2869 | 0.2806 | 0.3063 | 2.3366 | 2.3265 | 2.8365 | 2.7222 | 2.4873 | 2.6743 |
| Aspartic acid_HMDB0000191 | 0.3322 | 0.3283 | 0.3182 | 0.3788 | 0.3649 | 0.3552 | 0.1999 | 0.1699 | 0.1749 | 0.1910 | 0.1958 | 0.1706 | 2.2560 | 2.4069 | 2.6974 | 2.4842 | 2.4012 | 2.5747 |
| Azelaic acid_HMDB0000784 | 0.8651 | 0.6775 | 0.7862 | 0.6379 | 0.9674 | 1.2360 | 0.8969 | 0.7956 | 0.9382 | 1.3384 | 1.1925 | 0.5777 | 1.5882 | 1.0865 | 1.1198 | 0.8341 | 0.7938 | 1.6682 |
| Benzoic acid_HMDB0001870 | 1.1844 | 1.0649 | 1.0491 | 0.9703 | 1.1530 | 1.1314 | 0.6871 | 0.7294 | 0.5780 | 1.0763 | 0.7543 | 0.8792 | 1.1519 | 1.2731 | 1.1561 | 1.1052 | 0.9875 | 1.0688 |
| Beta-Alanine_HMDB0000056 | 0.8634 | 0.9167 | 0.9637 | 0.9736 | 1.0255 | 1.2453 | 0.8400 | 0.8200 | 0.7418 | 0.7564 | 0.7051 | 0.7614 | 1.1299 | 1.2527 | 1.2694 | 1.2753 | 1.1611 | 1.2986 |
| Beta-Glycerophosphoric acid_HMDB0002520 | 0.9204 | 1.1386 | 1.1480 | 1.1792 | 0.8097 | 0.9634 | 1.3474 | 0.9950 | 0.9475 | 1.2209 | 1.0431 | 1.0962 | 0.8357 | 0.7197 | 0.9582 | 1.0061 | 0.7204 | 0.9506 |
| Cadaverine_HMDB0002322 | 0.8280 | 1.1138 | 0.8969 | 0.8400 | 0.9864 | 1.0016 | 0.7820 | 0.7620 | 0.6764 | 0.8025 | 0.6625 | 0.6798 | 1.1464 | 1.4077 | 1.4086 | 1.3200 | 1.2401 | 1.4453 |
| Capric acid_HMDB0000511 | 1.1462 | 1.1921 | 0.9833 | 0.8727 | 1.0283 | 1.1771 | 0.7750 | 0.8119 | 0.7883 | 0.8974 | 0.7934 | 0.7494 | 1.2272 | 1.2879 | 1.1423 | 1.0231 | 0.9117 | 1.1925 |
| Caproic acid_HMDB0000535 | 1.1155 | 1.0755 | 0.9599 | 0.9130 | 0.9837 | 1.0477 | 0.9179 | 0.8819 | 0.8688 | 1.0789 | 0.9670 | 0.9191 | 1.1168 | 1.0985 | 1.1205 | 1.0221 | 0.9301 | 0.9832 |
| Caprylic acid_HMDB0000482 | 1.2251 | 1.1509 | 1.0351 | 0.9199 | 1.1241 | 1.1807 | 0.6255 | 0.6771 | 0.4850 | 1.0102 | 0.7711 | 0.7919 | 1.2186 | 1.2026 | 1.0945 | 1.2541 | 1.0653 | 1.1684 |
| Cholesterol_HMDB0000067 | 0.8811 | 0.9849 | 0.9034 | 0.9382 | 0.9696 | 0.9067 | 0.7906 | 0.6846 | 0.6548 | 0.7593 | 0.7432 | 0.6894 | 1.1518 | 1.2894 | 1.4783 | 1.3235 | 1.3266 | 1.5246 |
| cis-Aconitic acid_HMDB0000072 | 0.3285 | 0.3318 | 0.3290 | 0.3515 | 0.4419 | 0.3890 | 0.2859 | 0.2227 | 0.2623 | 0.3135 | 0.3040 | 0.2616 | 2.3240 | 2.1772 | 2.5027 | 2.2968 | 2.2977 | 2.5799 |
| Citramalic acid_HMDB0000426 | 0.9632 | 0.7187 | 0.7586 | 0.5303 | 0.6872 | 1.6345 | 0.7482 | 0.8555 | 1.0038 | 1.5411 | 1.5840 | 0.7539 | 1.4181 | 0.6941 | 0.8644 | 0.8176 | 1.0918 | 1.3350 |
| Citric acid_HMDB0000094 | 0.2894 | 0.3106 | 0.3029 | 0.3311 | 0.3101 | 0.3219 | 0.2075 | 0.1922 | 0.2008 | 0.2409 | 0.3085 | 0.2102 | 2.2772 | 2.3688 | 2.5364 | 2.3129 | 2.4831 | 2.7954 |
| Creatinine_HMDB0000562 | 1.0668 | 0.7500 | 1.2186 | 1.2232 | 1.2765 | 1.0216 | 1.1588 | 0.5897 | 0.7406 | 1.2184 | 1.0203 | 1.0094 | 1.2826 | 0.5239 | 1.0812 | 1.1107 | 0.9399 | 0.7678 |
| Cystathionine_HMDB0000099 | 0.9180 | 0.8165 | 0.8234 | 0.8736 | 0.8429 | 0.8191 | 0.3510 | 0.2901 | 0.3133 | 0.2643 | 0.2852 | 0.3034 | 1.7717 | 1.6294 | 2.1150 | 1.8810 | 1.6609 | 2.0410 |
| Cysteine_HMDB0000574 | 0.9663 | 0.7496 | 1.1409 | 1.2632 | 1.3533 | 1.1279 | 0.8635 | 0.6020 | 0.6961 | 0.7951 | 0.6724 | 0.6949 | 1.1175 | 0.7984 | 1.2177 | 1.3446 | 1.3374 | 1.2590 |
| Cytosine_HMDB0000630 | 0.9017 | 1.0815 | 1.1162 | 0.8577 | 0.8903 | 0.4650 | 1.1702 | 0.9991 | 1.0267 | 0.6128 | 0.5365 | 0.9750 | 0.8997 | 1.4817 | 1.4309 | 1.2541 | 1.1246 | 1.1763 |
| Dihydroxyacetone_HMDB0001882 | 1.4792 | 1.4257 | 1.4449 | 1.5803 | 1.7518 | 1.5155 | 0.6149 | 0.5458 | 0.5860 | 0.7069 | 0.7371 | 0.6173 | 0.8384 | 0.7078 | 0.8913 | 0.7869 | 0.8250 | 0.9452 |
| Dihydroxyacetone phosphate_HMDB0001473 | 0.8393 | 0.3962 | 0.7293 | 1.1087 | 1.3936 | 1.8485 | 0.0916 | 0.0824 | 0.1101 | 0.3289 | 0.2002 | 0.0591 | 3.3812 | 0.4809 | 0.8944 | 1.2781 | 1.5138 | 3.2638 |
| Dimethylglycine_HMDB0000092 | 1.5675 | 1.3814 | 1.5941 | 1.4774 | 1.5137 | 0.9744 | 0.6371 | 0.5839 | 0.6403 | 0.5120 | 0.5530 | 0.5854 | 0.6164 | 1.4342 | 1.3274 | 1.0588 | 0.8807 | 0.6621 |
| Docosahexaenoic acid_HMDB0002183 | NA | NA | -1.6624 | -3.9010 | -5.4481 | -3.8456 | -6.5630 | NA | NA | -2.3339 | NA | NA | -11.8426 | NA | NA | NA | NA | -2.2852 |
| Dodecanoic acid_HMDB0000638 | 1.5119 | 0.9880 | 0.5941 | 0.5979 | 0.6147 | 1.0638 | 0.7315 | 0.9459 | 0.7525 | 0.8230 | 1.1139 | 0.5717 | 1.5568 | 1.5105 | 1.1003 | 0.8161 | 0.9011 | 1.8062 |
| Dopamine_HMDB0000073 | 0.8820 | 0.9514 | 0.7223 | 0.8268 | 0.8652 | 0.8242 | 0.7407 | 0.6573 | 0.7220 | 0.7210 | 0.7090 | 0.6447 | 1.2428 | 1.4459 | 1.5920 | 1.4156 | 1.4940 | 1.5429 |
| Eicosapentaenoic acid_HMDB0001999 | 1.1238 | 1.2040 | 0.8216 | 0.9064 | 0.7101 | 0.5395 | 1.1550 | 1.0069 | 1.0015 | 0.6243 | 0.5720 | 1.2048 | 0.8595 | 1.2613 | 1.4238 | 1.0034 | 0.9053 | 1.6769 |
| Elaidic acid_HMDB0000573 | 1.0797 | 1.3200 | 0.8494 | 0.8727 | 0.7970 | 0.7165 | 0.7824 | 0.8340 | 0.8107 | 0.5246 | 0.6497 | 0.7466 | 1.0081 | 1.5938 | 1.5483 | 1.2091 | 1.2530 | 1.4044 |
| Erythritol_HMDB0002994 | 0.9350 | 0.8653 | 0.8174 | 0.8761 | 0.8874 | 0.8196 | 0.9067 | 0.8255 | 0.8394 | 0.8789 | 0.8038 | 0.7558 | 1.2808 | 1.2091 | 1.3664 | 1.2946 | 1.2613 | 1.3768 |
| Ethanolamine_HMDB0000149 | 1.0963 | 1.0837 | 1.0413 | 1.2328 | 1.1853 | 1.4427 | 0.9513 | 0.8743 | 0.7566 | 1.1141 | 0.9988 | 0.8966 | 0.9966 | 0.7969 | 0.9177 | 0.8656 | 0.7479 | 1.0015 |
| Fructose_HMDB0000660 | 1.0316 | 0.8749 | 0.7827 | 0.8217 | 0.8088 | 0.8633 | 1.0633 | 0.8875 | 1.1328 | 1.0849 | 0.9291 | 0.9080 | 1.4820 | 0.8712 | 1.0259 | 1.1985 | 1.0427 | 1.1912 |
| Fucose_HMDB0029196 | 1.3889 | 0.2010 | 0.6176 | 1.0053 | 1.0358 | 1.3985 | 1.1119 | 0.7173 | 0.6925 | 0.4423 | 0.6599 | 0.7961 | 1.8743 | 0.9744 | 1.0409 | 1.3764 | 1.2366 | 1.4303 |
| Fumaric acid_HMDB0000134 | 0.3855 | 0.3765 | 0.3902 | 0.4285 | 0.4665 | 0.4180 | 0.3002 | 0.2499 | 0.2860 | 0.3412 | 0.3259 | 0.2899 | 2.1650 | 2.0113 | 2.3866 | 2.2762 | 2.2361 | 2.6664 |
| Galactitol_HMDB0000107 | 1.1006 | 1.0894 | 0.9946 | 0.9891 | 0.8978 | 1.0297 | 0.9588 | 0.7833 | 1.2128 | 1.1771 | 1.1955 | 0.8216 | 1.2739 | 0.7474 | 0.8176 | 0.8219 | 0.7761 | 1.3127 |
| Gallic acid_HMDB0005807 | 0.6762 | NA | 1.3885 | 0.8100 | 0.3037 | 1.1535 | 1.4789 | 0.3435 | 0.7449 | 1.6597 | 0.3327 | 0.2784 | 1.0667 | 0.7413 | 0.5098 | 2.0683 | 1.2330 | 3.2326 |
| Gamma-Aminobutyric acid_HMDB0000112 | 0.7381 | 0.8269 | 0.7849 | 0.7934 | 0.8658 | 0.8590 | 1.4569 | 1.3135 | 1.2695 | 1.3918 | 1.3172 | 1.3024 | 0.7181 | 0.8633 | 0.9290 | 0.8249 | 0.8353 | 0.9100 |
| Glucaric acid_HMDB0000663 | 1.0558 | 1.0638 | 0.9230 | 0.9110 | 0.8871 | 0.8375 | 0.7724 | 0.6138 | 0.7681 | 0.7844 | 0.7784 | 0.6603 | 1.3409 | 1.2279 | 1.2093 | 1.2764 | 1.1747 | 1.7151 |
| Gluconic acid_HMDB0000625 | 1.0241 | 0.9106 | 0.8057 | 0.9481 | 0.7585 | 0.8606 | 0.5621 | 0.7013 | 0.6107 | 0.6088 | 0.6259 | 0.5235 | 1.6772 | 1.3429 | 1.3736 | 1.3957 | 1.4428 | 1.8278 |
| Glucosamine_HMDB0001514 | 1.2578 | 1.0376 | 0.3610 | 0.7661 | 0.3811 | 0.3224 | 1.1187 | 0.7863 | 1.1617 | 0.8888 | 0.7117 | 0.8465 | 2.2550 | 0.9468 | 0.9906 | 1.4678 | 1.2600 | 1.4402 |
| Glucose 6-phosphate_HMDB0001401 | 0.6980 | 0.5324 | 0.5231 | 0.6105 | 0.5224 | 0.6576 | 1.4505 | 1.1231 | 1.5202 | 1.5371 | 1.4747 | 1.1757 | 1.4659 | 0.7726 | 0.8867 | 1.0208 | 0.8602 | 1.1685 |
| Glucose_HMDB0000122 | 1.3173 | 0.8050 | 0.6744 | 0.6094 | 0.5688 | 0.6410 | 0.8720 | 0.8076 | 1.4082 | 1.0260 | 0.7479 | 0.8029 | 2.5561 | 0.8334 | 0.6220 | 1.3279 | 1.1684 | 1.2117 |
| Glutamate, gamma-methyl ester_HMDB0061715 | 0.7048 | 0.3497 | 0.7511 | 0.7980 | 0.6874 | 0.5490 | 0.6215 | 0.5325 | 0.5707 | 0.7201 | 0.6938 | 0.6425 | 2.0162 | 1.1113 | 1.8199 | 1.5214 | 1.9090 | 2.0011 |
| Glutamic acid_HMDB0000148 | 0.4850 | 0.6006 | 0.5536 | 0.5967 | 0.6052 | 0.5654 | 0.4430 | 0.3750 | 0.3709 | 0.4900 | 0.4227 | 0.4123 | 1.9229 | 1.9265 | 2.1037 | 2.0291 | 1.9194 | 2.1779 |
| Glutamine_HMDB0000641 | 0.9397 | 0.8786 | 0.9625 | 0.9737 | 0.9535 | 0.9190 | 0.7390 | 0.5799 | 0.6941 | 0.7130 | 0.6572 | 0.6374 | 1.4132 | 1.3258 | 1.4310 | 1.3964 | 1.3531 | 1.4330 |
| Glutaric acid_HMDB0000661 | 0.9580 | 0.9685 | 0.9189 | 0.9067 | 1.0129 | 1.0656 | 1.8367 | 1.6289 | 1.6825 | 1.8946 | 1.8391 | 1.6166 | 0.3441 | 0.2503 | 0.2482 | 0.2408 | 0.2397 | 0.3477 |
| Glutathione_HMDB0000125 | 0.1776 | 0.0755 | 1.1955 | 0.8859 | 1.1969 | 0.6961 | 0.9484 | 0.1589 | 0.2975 | 0.7952 | 0.3469 | 0.5283 | 2.3347 | 0.3351 | 1.1416 | 2.7670 | 2.5281 | 1.5908 |
| Glyceraldehyde 3-phosphate_HMDB0001112 | 1.0707 | 0.5433 | 1.0422 | 0.7844 | 1.0477 | 1.1651 | 0.2031 | 0.2964 | 0.1639 | 0.2416 | 0.1437 | 0.0704 | 4.0436 | 0.6276 | 0.9122 | 0.9073 | 1.2567 | 3.4801 |
| Glyceric acid_HMDB0000139 | 0.9275 | 0.9399 | 0.8091 | 0.9066 | 0.8758 | 1.1731 | 1.1316 | 1.0569 | 1.0893 | 1.4830 | 1.3219 | 1.1796 | 0.9700 | 0.8651 | 0.8111 | 0.7659 | 0.7458 | 0.9477 |
| Glycerol 1-octadecanoate_HMDB0031075 | 1.1026 | 1.0366 | 1.0291 | 1.0199 | 1.1186 | 1.0924 | 0.3818 | 0.2868 | 0.3113 | 0.4753 | 0.3872 | 0.3508 | 1.4906 | 1.4072 | 1.7017 | 1.5906 | 1.3836 | 1.8338 |
| Glycerol 3-phosphate_HMDB0000126 | 0.6324 | 0.7171 | 0.8543 | 0.6451 | 0.7474 | 0.6728 | 1.7897 | 1.2793 | 1.3084 | 1.6498 | 1.4200 | 1.4060 | 0.7789 | 0.7811 | 0.8538 | 0.7974 | 0.8082 | 0.8583 |
| Glycerol_HMDB0000131 | 1.0955 | 1.0036 | 0.8715 | 0.9348 | 0.9725 | 1.3797 | 0.7769 | 0.7570 | 0.5245 | 1.3902 | 1.1966 | 0.7404 | 1.2819 | 0.8639 | 1.0216 | 0.9492 | 0.8985 | 1.3417 |
| Glycine_HMDB0000123 | 1.0347 | 1.0555 | 1.0441 | 1.0278 | 1.0796 | 1.1448 | 1.0135 | 1.0303 | 0.9766 | 0.9866 | 0.9748 | 0.9626 | 0.9202 | 0.9488 | 0.9672 | 0.9564 | 0.9055 | 0.9707 |
| Glycolic acid_HMDB0000115 | 0.9576 | 0.9464 | 0.9194 | 0.9344 | 1.0229 | 1.0556 | 0.7934 | 0.7441 | 0.8041 | 1.1232 | 1.3324 | 0.9136 | 1.0385 | 1.0946 | 0.9997 | 0.8945 | 1.1586 | 1.2670 |
| Glycyl-glycine_HMDB0011733 | 0.8036 | 0.6502 | 0.7662 | 0.7251 | 0.9568 | 0.7541 | 0.6888 | 0.6232 | 0.6897 | 0.6807 | 0.6282 | 0.7427 | 1.4421 | 1.2572 | 1.6354 | 1.5564 | 1.6049 | 1.7947 |
| Glyoxylic acid_HMDB0000119 | 1.5850 | 1.3866 | 1.6086 | 1.4928 | 1.5245 | 0.9695 | 0.6170 | 0.5761 | 0.6319 | 0.4992 | 0.5409 | 0.5798 | 0.6114 | 1.4444 | 1.3431 | 1.0594 | 0.8806 | 0.6492 |
| Heptadecanoic acid_HMDB0002259 | 0.9637 | 0.9245 | 0.6143 | 0.6536 | 0.6243 | 0.7410 | 0.7054 | 0.7385 | 0.7657 | 0.6193 | 0.8693 | 0.7016 | 1.3556 | 1.5674 | 1.6453 | 1.3158 | 1.3581 | 1.8367 |
| Homocysteine_HMDB0000742 | 0.4376 | 0.3700 | 0.4873 | 0.4814 | 0.4530 | 0.3878 | 0.2214 | 0.2010 | 0.2162 | 0.1846 | 0.1721 | 0.2197 | 2.0597 | 2.0602 | 2.5622 | 2.7147 | 2.4897 | 2.2814 |
| Homoserine_HMDB0000719 | 1.0162 | 0.9343 | 0.7698 | 0.7089 | 0.8388 | 0.8980 | 0.8275 | 0.7335 | 0.8388 | 0.3879 | 0.3770 | 0.9743 | 1.3735 | 1.1368 | 1.6154 | 1.5396 | 1.6489 | 1.3807 |
| Hydroquinone_HMDB0002434 | 1.1701 | 1.3021 | 0.9748 | 1.0608 | 0.9715 | 1.0413 | 0.7336 | 0.6292 | 0.6080 | 0.8288 | 0.8070 | 0.6829 | 1.2586 | 1.2574 | 1.3211 | 1.0801 | 1.0478 | 1.2251 |
| Hydroxylamine_HMDB0003338 | 0.8499 | 1.0006 | 1.0231 | 0.9434 | 1.0612 | 1.2279 | 1.0930 | 1.2390 | 1.1048 | 1.0230 | 0.9430 | 1.0493 | 0.8461 | 1.0341 | 0.8951 | 0.9650 | 0.8957 | 0.8058 |
| Hydroxyphenyllactic acid_HMDB0000755 | 0.5352 | 0.6058 | 0.4907 | 0.5136 | 0.5939 | 0.5253 | 1.2603 | 1.0700 | 1.1153 | 1.2139 | 1.0653 | 1.0847 | 1.1725 | 1.4153 | 1.3932 | 1.3150 | 1.2465 | 1.3835 |
| Hydroxypropionic acid_HMDB0000700 | 0.9064 | 0.9617 | 0.8438 | 0.8475 | 0.9699 | 0.9698 | 0.7733 | 0.7305 | 0.7206 | 1.0240 | 1.5255 | 0.9139 | 1.0258 | 1.1454 | 1.1778 | 0.9268 | 1.2375 | 1.2997 |
| Hypotaurine_HMDB0000965 | 0.8091 | 1.2839 | 1.0126 | 0.9141 | 1.0310 | 1.0685 | 0.8480 | 0.7956 | 0.7092 | 0.7897 | 0.7080 | 0.7103 | 1.0456 | 1.3687 | 1.2762 | 1.1444 | 1.1405 | 1.3447 |
| Indoleacetic acid_HMDB0000197 | 0.7452 | 1.2780 | 0.8813 | 0.7335 | 1.0370 | 1.1826 | 1.3165 | 0.6199 | 0.9318 | 1.5192 | 0.8152 | 0.7682 | 0.8600 | 1.4780 | 1.1644 | 0.4597 | 1.3041 | 0.9055 |
| Inositol phosphate_HMDB0002985 | 1.0870 | 1.2008 | 1.3767 | 0.9734 | 1.1035 | 0.7279 | 0.8865 | 0.7450 | 0.7598 | 0.5113 | 0.5388 | 0.6785 | 0.9187 | 1.4269 | 1.4049 | 1.1155 | 1.1826 | 1.3624 |
| Isocitric acid_HMDB0000193 | 0.3797 | 0.3093 | 0.3603 | 0.3659 | 0.4145 | 0.3329 | 0.2342 | 0.2181 | 0.2562 | 0.2208 | 0.2063 | 0.2300 | 2.3510 | 2.4157 | 2.5048 | 2.1927 | 2.4323 | 2.5752 |
| Isoleucine_HMDB0000172 | 0.9656 | 0.9572 | 0.9772 | 1.0240 | 1.0163 | 0.9969 | 0.7393 | 0.6253 | 0.6674 | 0.7293 | 0.6641 | 0.6659 | 1.2302 | 1.2270 | 1.4205 | 1.3689 | 1.2982 | 1.4266 |
| ISTD_Sorbitol | 1.0076 | 0.8961 | 0.8179 | 0.7950 | 0.7417 | 0.9789 | 0.8080 | 0.7315 | 1.1856 | 1.0084 | 1.1157 | 0.7568 | 1.5735 | 1.0334 | 1.0133 | 1.0112 | 0.9887 | 1.5368 |
| ISTD_Valine | 0.9441 | 0.9625 | 0.9582 | 0.9682 | 1.0258 | 1.0565 | 1.0280 | 0.9364 | 0.9199 | 1.0550 | 0.9879 | 0.9393 | 0.9625 | 1.0222 | 1.0757 | 1.0539 | 1.0406 | 1.0633 |
| Ketoleucine_HMDB0000695 | 0.7710 | 0.6412 | 0.6717 | 0.7561 | 0.7459 | 0.6984 | 1.2964 | 1.1826 | 1.2855 | 1.3479 | 1.2276 | 1.1664 | 1.0197 | 0.9741 | 1.0702 | 1.0183 | 1.0067 | 1.1202 |
| Lactic acid_HMDB0000190 | 0.8933 | 0.9265 | 0.9063 | 0.9767 | 0.9697 | 0.8818 | 1.1921 | 1.0762 | 1.1405 | 1.1621 | 1.0843 | 1.0743 | 0.8409 | 0.9366 | 0.9869 | 0.9488 | 0.9704 | 1.0328 |
| Lactitol_HMDB0040937 | 1.0096 | 0.6479 | 0.9245 | 0.8949 | 0.8212 | 0.7193 | 0.5281 | 0.6569 | 0.8398 | 0.6562 | 0.6077 | 0.7428 | 1.5506 | 1.2387 | 1.5496 | 1.5725 | 1.4197 | 1.6201 |
| Lathosterol_HMDB0001170 | 0.8479 | 0.8806 | 0.8651 | 0.7487 | 0.7156 | 0.8886 | 0.1906 | 0.3767 | 0.4935 | 0.3055 | 0.3764 | 0.4749 | 1.6813 | 1.6201 | 1.9160 | 2.0132 | 1.7904 | 1.8149 |
| Leucine_HMDB0000687 | 0.9724 | 0.9711 | 0.9670 | 1.0211 | 1.0081 | 1.0002 | 0.8093 | 0.6928 | 0.7356 | 0.8041 | 0.7296 | 0.7330 | 1.1717 | 1.1711 | 1.3481 | 1.2916 | 1.2231 | 1.3501 |
| Levoglucosan_HMDB0000640 | 0.8674 | 0.8485 | 0.8354 | 0.8544 | 0.9003 | 1.0690 | 0.5961 | 0.6419 | 0.6438 | 0.7120 | 0.7609 | 0.5938 | 1.5977 | 1.2113 | 1.4900 | 1.1744 | 1.3480 | 1.8551 |
| Lysine_HMDB0000182 | 1.0530 | 0.8546 | 0.8517 | 0.8360 | 0.8600 | 0.8285 | 0.8025 | 0.7606 | 0.8778 | 0.7141 | 0.6698 | 0.7007 | 1.5280 | 1.2426 | 1.2867 | 1.3555 | 1.3533 | 1.4247 |
| Maleic acid_HMDB0000176 | 0.7294 | 0.4378 | 0.6705 | 0.5819 | 0.8674 | 0.7735 | 0.4639 | 0.4075 | 0.5601 | 1.0410 | 0.7799 | 0.4041 | 1.6763 | 1.5322 | 1.8484 | 1.7818 | 1.6061 | 1.8384 |
| Malic acid_HMDB0000744 | 0.3398 | 0.3477 | 0.3297 | 0.3459 | 0.3694 | 0.3306 | 0.2767 | 0.2791 | 0.2999 | 0.2908 | 0.3236 | 0.2929 | 2.0595 | 2.3647 | 2.5507 | 2.2214 | 2.4124 | 2.5652 |
| Maltose_HMDB0000163 | 0.7854 | 0.8818 | 0.6660 | 0.7456 | 0.8046 | 0.7082 | 0.4473 | 0.4467 | 0.6492 | 0.5439 | 0.4275 | 0.5690 | 1.9643 | 1.3610 | 1.6751 | 1.7437 | 1.7916 | 1.7894 |
| Mannitol_HMDB0000765 | 0.8512 | 0.7514 | 0.6609 | 0.7960 | 0.6386 | 0.7993 | 0.7743 | 0.7320 | 0.9954 | 1.0718 | 0.9484 | 0.6973 | 1.7153 | 1.2728 | 1.2526 | 1.1739 | 1.2904 | 1.5784 |
| Mannose 6-phosphate_HMDB0001078 | 0.6529 | 0.5319 | 0.5660 | 0.6681 | 0.5942 | 0.6618 | 1.4898 | 1.2008 | 1.4112 | 1.5444 | 1.4356 | 1.2741 | 1.3420 | 0.7023 | 0.9456 | 1.0149 | 0.8826 | 1.0817 |
| Mesaconic acid_HMDB0000749 | 0.5798 | 0.7143 | 0.8292 | 0.8782 | 1.0014 | 1.0311 | 0.7446 | 0.5111 | 0.4199 | 0.7151 | 1.4946 | 0.8098 | 0.9612 | 0.9707 | 0.9365 | 1.1988 | 2.2861 | 1.9175 |
| Methionine_HMDB0000696 | 0.9734 | 0.9526 | 0.9763 | 1.0213 | 0.9733 | 1.0199 | 0.6597 | 0.5644 | 0.5931 | 0.6385 | 0.5882 | 0.6015 | 1.3359 | 1.2985 | 1.5247 | 1.4538 | 1.3346 | 1.4903 |
| Methionine sulfone_HMDB0062174 | 0.8815 | 0.8026 | 0.8814 | 0.8230 | 0.9524 | 0.8157 | 0.4771 | 0.3658 | 0.4350 | 0.3844 | 0.3689 | 0.4402 | 1.5274 | 1.5633 | 1.8982 | 1.7998 | 1.7341 | 1.8494 |
| Methylmalonic acid_HMDB0000202 | 0.4407 | 0.2671 | 0.3538 | 0.2642 | 0.3199 | 0.2555 | 0.3350 | 0.2721 | 0.3172 | 0.2615 | 0.3030 | 0.2790 | 2.1676 | 1.8356 | 2.5269 | 2.3558 | 2.7047 | 2.7403 |
| Methylsuccinic acid_HMDB0001844 | 0.9437 | 0.9589 | 0.8959 | 0.9097 | 0.9082 | 0.9971 | 0.8793 | 0.8299 | 1.1030 | 0.8326 | 0.9460 | 0.7114 | 1.1550 | 0.9844 | 1.3147 | 1.0574 | 1.3093 | 1.2637 |
| MG(18:0e/0:0/0:0)_HMDB0011143 | 0.7232 | 0.5547 | 0.4253 | 0.7490 | 0.4460 | 1.7041 | 0.3792 | 0.3645 | 0.3614 | 1.5878 | 1.7044 | 0.3129 | 2.4908 | 1.0024 | 1.1100 | 0.6564 | 0.7428 | 2.6851 |
| Myristic acid_HMDB0000806 | 1.1080 | 1.0557 | 0.7489 | 0.8308 | 0.7732 | 1.1122 | 0.8232 | 0.7549 | 0.9469 | 0.8069 | 0.8859 | 0.8199 | 1.2382 | 1.3009 | 1.3240 | 1.0553 | 1.0409 | 1.3743 |
| N-Acetylglutamine_HMDB0006029 | 1.2643 | 0.7732 | 0.6907 | 0.6136 | 0.5866 | 0.6230 | 0.9228 | 0.7885 | 1.4082 | 1.0362 | 0.7674 | 0.8365 | 2.6613 | 0.7638 | 0.5881 | 1.3210 | 1.1676 | 1.1872 |
| N-Acetyl-L-alanine_HMDB0000766 | 0.8003 | 0.9178 | 0.8065 | 0.7703 | 0.8387 | 0.6923 | 0.5698 | 0.5893 | 0.5918 | 0.5266 | 0.5716 | 0.4425 | 1.2996 | 1.7334 | 1.8786 | 1.6070 | 1.6066 | 1.7575 |
| N-Acetyl-L-aspartic acid_HMDB0000812 | 0.1717 | 0.2030 | 0.2001 | 0.1548 | 0.1675 | 0.1224 | 0.1860 | 0.1713 | 0.1478 | 0.1582 | 0.1240 | 0.1816 | 2.1829 | 2.2066 | 2.9913 | 3.0607 | 2.9306 | 2.6396 |
| N-Acetyl-L-glutamic acid_HMDB0001138 | 0.3016 | 0.3942 | 0.3352 | 0.3508 | 0.3878 | 0.3530 | 0.5471 | 0.4337 | 0.4333 | 0.5205 | 0.4437 | 0.4625 | 1.8400 | 2.1991 | 2.2946 | 2.1177 | 2.2296 | 2.3556 |
| N-Acetyl-L-methionine_HMDB0011745 | 0.7745 | 0.7742 | 1.2756 | 1.1336 | 1.2429 | 0.8082 | 1.1827 | 0.6900 | 0.7302 | 0.6993 | 0.6633 | 0.9157 | 0.8692 | 0.9322 | 1.3729 | 1.3976 | 1.2996 | 1.2383 |
| N-Acetylserine_HMDB0002931 | 0.8497 | 0.8449 | 0.8405 | 0.8756 | 0.8890 | 0.8935 | 0.4256 | 0.3490 | 0.3430 | 0.4062 | 0.3599 | 0.3549 | 1.5733 | 1.7138 | 1.9495 | 1.7229 | 1.6856 | 1.9231 |
| N-Formyl-L-Methionine_HMDB0001015 | 0.9783 | 1.0498 | 1.1100 | 1.1294 | 1.1660 | 1.0427 | 1.0230 | 0.7508 | 0.7779 | 0.8757 | 0.7393 | 0.8395 | 0.9364 | 0.9881 | 1.2080 | 1.0892 | 1.0956 | 1.2001 |
| Niacinamide_HMDB0001406 | 1.0079 | 0.9874 | 1.0128 | 1.0820 | 1.0886 | 0.9523 | 0.9816 | 0.7827 | 0.7694 | 0.6487 | 0.6626 | 0.7693 | 0.9812 | 1.2363 | 1.3726 | 1.2104 | 1.1891 | 1.2652 |
| Norepinephrine_HMDB0000216 | 0.6796 | 0.7352 | 0.8630 | 0.7424 | 0.8691 | 0.8391 | 0.3055 | 0.2554 | 0.3003 | 0.2698 | 0.2766 | 0.2515 | 1.8138 | 1.6944 | 1.9624 | 1.9807 | 2.0412 | 2.1201 |
| Octadecanol_HMDB0002350 | 0.8136 | 0.7865 | 0.6640 | 0.6401 | 0.5572 | 1.5468 | 0.6296 | 0.6025 | 0.7230 | 1.5343 | 1.4368 | 0.4663 | 1.8267 | 1.2514 | 0.9506 | 0.9078 | 0.7670 | 1.8958 |
| Oleic acid_HMDB0000207 | 1.0625 | 1.0995 | 0.6311 | 0.7009 | 0.5861 | 0.6721 | 0.6964 | 0.7312 | 0.6981 | 0.4637 | 0.6945 | 0.6502 | 1.2280 | 1.5650 | 1.8159 | 1.3686 | 1.4325 | 1.9037 |
| O-Phosphoethanolamine_HMDB0000224 | 0.7524 | 0.8408 | 0.7680 | 0.7956 | 0.9023 | 1.1302 | 0.9602 | 0.9538 | 0.7810 | 0.9858 | 1.0165 | 0.8511 | 0.9739 | 1.1755 | 1.2534 | 1.2073 | 1.2524 | 1.3999 |
| Ornithine_HMDB0000214 | 1.1029 | 0.8796 | 0.8720 | 0.8489 | 0.8806 | 0.8453 | 0.7220 | 0.7057 | 0.8400 | 0.6907 | 0.7461 | 0.6446 | 1.6092 | 1.2984 | 1.3022 | 1.3363 | 1.2894 | 1.3860 |
| Oxalacetic acid_HMDB0000223 | 0.4572 | 0.6900 | 0.9717 | 0.8688 | 0.9394 | 1.3946 | 0.3048 | 0.5410 | 0.3754 | 1.5028 | 1.0687 | 0.6564 | 1.4309 | 1.4645 | 0.9902 | 1.3412 | 1.5668 | 1.4355 |
| Oxalic acid_HMDB0002329 | 0.9403 | 0.9600 | 0.9746 | 0.9675 | 0.9722 | 1.0301 | 0.9844 | 0.9867 | 1.0458 | 1.1083 | 1.0827 | 0.9790 | 1.0251 | 0.9973 | 0.9561 | 0.9246 | 1.0007 | 1.0644 |
| Oxoglutaric acid_HMDB0000208 | 0.4210 | 0.4057 | 0.4193 | 0.4693 | 0.5199 | 0.4678 | 0.7485 | 0.5895 | 0.6460 | 0.7417 | 0.6511 | 0.5645 | 1.5936 | 1.7439 | 2.1874 | 1.8605 | 1.8361 | 2.1343 |
| Palmitic acid_HMDB0000220 | 1.0957 | 1.2203 | 0.6543 | 0.7830 | 0.6808 | 0.9233 | 0.7055 | 0.7290 | 0.7622 | 0.6331 | 0.8724 | 0.6543 | 1.3854 | 1.4496 | 1.4784 | 1.1290 | 1.1514 | 1.6923 |
| Palmitoleic acid_HMDB0003229 | 1.0752 | 1.2944 | 0.8085 | 0.8496 | 0.7814 | 0.6356 | 0.7107 | 0.6752 | 0.6552 | 0.3884 | 0.5425 | 0.6408 | 1.0268 | 1.8261 | 1.7333 | 1.4126 | 1.4313 | 1.5124 |
| Pantothenic acid_HMDB0000210 | 0.8261 | 0.8576 | 0.7710 | 0.8183 | 0.8327 | 0.7393 | 0.8007 | 0.6881 | 0.7323 | 0.7660 | 0.7297 | 0.6986 | 1.3137 | 1.4061 | 1.5651 | 1.4199 | 1.4323 | 1.6023 |
| Pelargonic acid_HMDB0000847 | 1.2698 | 1.1633 | 1.0404 | 0.9914 | 1.1998 | 1.2135 | 0.7148 | 0.7678 | 0.4998 | 0.8505 | 0.6125 | 0.8061 | 1.1477 | 1.4114 | 1.0402 | 1.1660 | 1.0821 | 1.0229 |
| Phenylalanine_HMDB0000159 | 0.9512 | 0.9345 | 0.9447 | 0.9908 | 0.9823 | 0.9833 | 0.8034 | 0.6806 | 0.7209 | 0.7819 | 0.7131 | 0.7177 | 1.2660 | 1.2450 | 1.3434 | 1.3093 | 1.2818 | 1.3501 |
| Phenyllactic acid_HMDB0000779 | 1.0647 | 0.9149 | 0.8380 | 0.9215 | 0.7467 | 0.7955 | 0.5884 | 0.6885 | 0.8729 | 0.4889 | 0.9136 | 0.6788 | 1.3033 | 1.3339 | 1.5421 | 1.3636 | 1.3456 | 1.5990 |
| Phosphoenolpyruvic acid_HMDB0000263 | 1.2260 | 1.2232 | 1.2923 | 1.1167 | 1.1234 | 1.1005 | 0.4470 | 0.3447 | 0.4526 | 0.4268 | 0.3517 | 0.3571 | 1.3540 | 1.4545 | 1.2435 | 1.4073 | 1.6910 | 1.3877 |
| Phosphoric acid_HMDB0002142 | 0.9390 | 0.9156 | 1.0726 | 1.0467 | 1.0904 | 0.9762 | 1.0582 | 0.8939 | 0.9248 | 1.0091 | 0.9619 | 0.9602 | 1.0005 | 0.9717 | 1.0390 | 1.0665 | 1.0377 | 1.0358 |
| Phosphoserine_HMDB0000272 | 0.9761 | 0.8336 | 1.1376 | 0.8639 | 0.8595 | 0.5451 | 0.9570 | 0.5729 | 0.7693 | 0.6686 | 0.6144 | 0.6427 | 1.6282 | 1.1564 | 1.4282 | 1.1805 | 1.6375 | 1.5285 |
| p-Hydroxyphenylacetic acid_HMDB0000020 | 0.5520 | 1.3643 | 0.8785 | 0.8846 | 1.0472 | 0.9012 | 0.9306 | 0.7693 | 0.7507 | 0.5926 | 0.8596 | 0.5574 | 1.4849 | 1.1412 | 1.2118 | 1.4092 | 1.0739 | 1.5911 |
| Pimelic acid_HMDB0000857 | 0.3874 | 0.8616 | 0.6580 | 0.4544 | 0.6764 | 2.2853 | 0.3966 | 0.6856 | 1.3278 | 2.1014 | 1.8033 | 0.1629 | 1.8361 | 0.8642 | 0.7710 | 0.3796 | 0.8603 | 1.4881 |
| Pipecolic acid_HMDB0000070 | 0.9257 | 0.9416 | 1.1085 | 0.9413 | 1.1063 | 0.9074 | 1.0340 | 0.9100 | 0.9337 | 0.8842 | 0.8582 | 0.9326 | 0.9707 | 1.1615 | 1.1254 | 1.0421 | 1.0792 | 1.1376 |
| p-Octopamine_HMDB0004825 | 0.8193 | 0.7821 | 0.9217 | 0.7833 | 0.8255 | 0.7115 | 0.7537 | 0.6584 | 0.9048 | 0.7481 | 0.7434 | 0.7249 | 1.2191 | 1.1678 | 1.6503 | 1.5352 | 1.5533 | 1.4975 |
| Proline_HMDB0000162 | 2.0903 | 2.2697 | 2.1583 | 2.1947 | 2.2961 | 2.1446 | 0.5432 | 0.4632 | 0.4692 | 0.5338 | 0.5013 | 0.4667 | 0.2845 | 0.2892 | 0.3316 | 0.3194 | 0.3123 | 0.3321 |
| Putrescine_HMDB0001414 | 0.9040 | 0.6632 | 1.0887 | 1.0820 | 1.3416 | 1.2305 | 0.3988 | 0.4761 | 0.3739 | 0.2859 | 0.4895 | 0.1915 | 2.3038 | 0.7684 | 1.2180 | 1.2789 | 1.6587 | 2.2463 |
| Pyridoxine_HMDB0000239 | 1.0582 | 0.9956 | 0.8360 | 0.8374 | 0.7777 | 0.8611 | 0.6710 | 0.5865 | 0.7740 | 0.7267 | 0.6497 | 0.6379 | 1.6308 | 1.2763 | 1.3890 | 1.3696 | 1.3092 | 1.6135 |
| Pyroglutamic acid_HMDB0000267 | 0.7982 | 0.8234 | 0.7935 | 0.8481 | 0.8394 | 0.8515 | 0.7455 | 0.6356 | 0.6190 | 0.7145 | 0.6401 | 0.6626 | 1.3283 | 1.4406 | 1.6355 | 1.5499 | 1.4820 | 1.5923 |
| Pyruvic acid_HMDB0000243 | 0.8803 | 0.8538 | 0.8589 | 1.0352 | 1.0302 | 0.9766 | 0.7016 | 0.6015 | 0.7280 | 0.6816 | 0.6767 | 0.6382 | 1.2935 | 1.2608 | 1.5193 | 1.4389 | 1.3015 | 1.5233 |
| Ribitol_HMDB0000508 | 1.2555 | 1.3209 | 1.2122 | 1.2411 | 1.2113 | 1.1403 | 0.7286 | 0.6381 | 0.7300 | 0.7053 | 0.7036 | 0.6707 | 1.0756 | 0.9592 | 1.1000 | 1.0583 | 1.0565 | 1.1927 |
| Ribose 5-phosphate_HMDB0001548 | 0.9481 | 1.0783 | 1.1143 | 1.0549 | 1.1086 | 1.1335 | 0.7081 | 0.5017 | 0.5300 | 0.7406 | 0.6861 | 0.5774 | 1.3046 | 1.1542 | 1.3428 | 1.1775 | 1.2985 | 1.5405 |
| Ribose_HMDB0000283 | 1.0196 | 0.7101 | 0.8713 | 1.2964 | 1.3856 | 1.4651 | 0.6122 | 0.5022 | 0.6501 | 1.1372 | 1.1019 | 0.4928 | 1.4776 | 0.7132 | 0.8901 | 1.0346 | 1.1349 | 1.5051 |
| Ribulose_HMDB0000621 | 1.2827 | 0.6410 | 0.7823 | 1.3258 | 1.4961 | 2.2276 | 0.8760 | 0.5813 | 0.8885 | 1.2999 | 1.4402 | 0.6522 | 1.3662 | 0.2868 | 0.3653 | 0.6000 | 0.6126 | 1.2755 |
| (S)-3-Hydroxyisobutyric acid_HMDB0000023 | 0.6620 | 0.6163 | 0.5556 | 0.5281 | 0.5750 | 0.4879 | 0.4955 | 0.5161 | 0.5321 | 0.5091 | 0.5172 | 0.4759 | 1.6973 | 1.8701 | 2.0281 | 1.8269 | 1.9696 | 2.1372 |
| Saccharopine_HMDB0000279 | 0.2746 | 0.2176 | 0.4994 | 0.3740 | 0.4640 | 0.3586 | 4.3205 | 1.5211 | 2.0604 | 1.4661 | 1.3870 | 1.9892 | 0.5180 | 0.2314 | 0.5414 | 0.6587 | 0.5723 | 0.5458 |
| Salicylic acid_HMDB0001895 | 1.4411 | 0.8399 | 0.9616 | 0.9321 | 0.7480 | 1.2340 | 0.7314 | 0.7917 | 0.9739 | 1.0410 | 0.8749 | 0.5696 | 1.2172 | 1.2545 | 1.6689 | 0.9004 | 0.9314 | 0.8886 |
| scyllo-Inositol_HMDB0006088 | 0.6294 | 0.7278 | 0.9909 | 1.2015 | 1.4926 | 0.8549 | 1.6153 | 1.1404 | 0.7810 | 1.1241 | 1.1565 | 1.1841 | 0.3927 | 0.7879 | 0.9406 | 0.9742 | 1.1314 | 0.8745 |
| Sedoheptulose 7-phosphate_HMDB0001068 | 1.2084 | 0.7116 | 0.8589 | 1.0453 | 0.7199 | 0.6568 | 1.3474 | 1.1241 | 1.3090 | 1.2020 | 1.5344 | 1.2348 | 1.1571 | 0.5912 | 0.9598 | 0.7598 | 0.5692 | 1.0105 |
| Serine_HMDB0000187 | 0.7917 | 0.8309 | 0.7875 | 0.8689 | 0.8904 | 0.8106 | 1.8553 | 1.7317 | 1.7871 | 1.8311 | 1.8155 | 1.7873 | 0.3531 | 0.3416 | 0.4200 | 0.3592 | 0.3339 | 0.4042 |
| Serotonin_HMDB0000259 | 0.7826 | 0.8097 | 1.3413 | 1.2631 | 1.3804 | 1.0727 | 1.0447 | 0.3687 | 0.5387 | 0.8221 | 0.6486 | 0.8093 | 1.2762 | 0.8611 | 1.1203 | 1.5169 | 1.2635 | 1.0801 |
| Sorbitol_HMDB0000247 | 1.0971 | 1.0864 | 0.9824 | 0.9917 | 0.8961 | 1.0384 | 0.9495 | 0.7876 | 1.2351 | 1.1824 | 1.1918 | 0.8086 | 1.2630 | 0.7587 | 0.8228 | 0.8275 | 0.7797 | 1.3011 |
| Sorbose_HMDB0001266 | 1.0228 | 0.8591 | 0.7981 | 0.8434 | 0.8100 | 0.8460 | 1.1206 | 0.9246 | 1.1248 | 1.1104 | 0.9466 | 0.9633 | 1.3942 | 0.8449 | 0.9827 | 1.1605 | 1.0635 | 1.1846 |
| Stearic acid_HMDB0000827 | 1.0549 | 1.1030 | 0.6442 | 0.7307 | 0.6753 | 0.8748 | 0.7811 | 0.7901 | 0.8144 | 0.6112 | 0.9725 | 0.7167 | 1.4248 | 1.4916 | 1.3873 | 1.0495 | 1.0784 | 1.7994 |
| Stigmasterol_HMDB0000937 | 1.2343 | 0.8022 | 0.0052 | 0.2455 | 0.0077 | 1.4198 | 0.1859 | 0.5725 | 0.4095 | 0.7463 | 1.7729 | 0.2598 | 2.3038 | 0.9703 | 1.9010 | 0.5845 | 0.9527 | 3.6260 |
| Succinic acid_HMDB0000254 | 2.4186 | 2.5630 | 2.4723 | 2.4975 | 2.5715 | 2.4393 | 0.5030 | 0.4390 | 0.4559 | 0.4909 | 0.4718 | 0.4434 | 0.0347 | 0.0377 | 0.0408 | 0.0398 | 0.0393 | 0.0416 |
| Sucrose_HMDB0000258 | 0.6681 | 0.7028 | 0.7665 | 0.9264 | 0.6730 | 0.9384 | 0.8119 | 0.7870 | 0.8178 | 1.5333 | 1.1198 | 0.9006 | 1.2133 | 1.3463 | 1.3320 | 0.7798 | 1.2815 | 1.4016 |
| Taurine_HMDB0000251 | 0.9981 | 1.0624 | 1.0851 | 1.1514 | 1.1540 | 1.0522 | 0.9935 | 0.7394 | 0.7567 | 0.8657 | 0.7560 | 0.8457 | 0.9524 | 0.9676 | 1.2205 | 1.0994 | 1.0969 | 1.2029 |
| Theanine_HMDB0034365 | 0.4529 | 1.0445 | 1.0952 | 1.0386 | 0.3972 | 1.0622 | 0.8161 | 0.3147 | 1.6352 | 1.7312 | 1.6485 | 1.0751 | 1.1857 | 0.8317 | 1.1134 | 0.5655 | 0.6922 | 1.3001 |
| Threitol_HMDB0004136 | 1.0115 | 0.9276 | 0.9827 | 1.0267 | 1.0301 | 0.9613 | 0.7171 | 0.6298 | 0.7498 | 0.7848 | 0.6801 | 0.6700 | 1.2891 | 1.3042 | 1.3818 | 1.2824 | 1.1427 | 1.4283 |
| Threonic acid_HMDB0000943 | 0.8321 | 0.8743 | 0.8142 | 0.8416 | 0.8370 | 0.8020 | 0.8676 | 0.7396 | 0.7830 | 0.8576 | 0.8027 | 0.7723 | 1.2375 | 1.2994 | 1.4666 | 1.3207 | 1.3479 | 1.5039 |
| Threonine_HMDB0000167 | 0.9993 | 0.9914 | 1.0319 | 1.0643 | 1.0474 | 1.0777 | 0.5872 | 0.4874 | 0.5254 | 0.5820 | 0.5309 | 0.5253 | 1.3811 | 1.3721 | 1.4804 | 1.4549 | 1.3919 | 1.4695 |
| Thymine_HMDB0000262 | 0.8143 | 0.8719 | 0.8240 | 0.7464 | 0.8203 | 0.6701 | 1.1487 | 0.9081 | 1.0599 | 0.9625 | 0.8600 | 1.0655 | 1.2308 | 1.2233 | 1.2426 | 1.2200 | 1.1324 | 1.1992 |
| Triethanolamine_HMDB0032538 | 0.3876 | 0.2482 | 0.3029 | 0.5261 | 0.9829 | 2.5565 | 0.4360 | 0.3200 | 0.3823 | 3.5965 | 2.0625 | 0.3596 | 2.0797 | 0.4667 | 0.5159 | 0.5557 | 0.5073 | 1.7136 |
| Tryptamine_HMDB0000303 | 1.0552 | 0.9390 | 0.9706 | 0.8758 | 0.9841 | 0.9048 | 0.5050 | 0.4730 | 0.5338 | 0.3470 | 0.3580 | 0.3278 | 1.5152 | 1.5172 | 1.6866 | 1.5731 | 1.6984 | 1.7355 |
| Tryptophan_HMDB0000929 | 0.7188 | 0.6987 | 1.0562 | 1.0867 | 1.0946 | 0.8374 | 0.8701 | 0.4566 | 0.5352 | 0.6894 | 0.5347 | 0.6499 | 1.2776 | 1.1195 | 1.5147 | 1.7742 | 1.5486 | 1.5372 |
| Tyramine_HMDB0000306 | 1.0233 | 0.8746 | 0.8790 | 0.8385 | 0.8621 | 0.8140 | 0.8065 | 0.7688 | 0.8927 | 0.7419 | 0.6789 | 0.7264 | 1.4608 | 1.2673 | 1.2645 | 1.3371 | 1.3541 | 1.4095 |
| Tyrosine_HMDB0000158 | 0.8798 | 0.8526 | 0.8415 | 0.8909 | 0.8727 | 0.8507 | 0.7266 | 0.6166 | 0.6647 | 0.6957 | 0.6382 | 0.6478 | 1.3971 | 1.3253 | 1.5696 | 1.4983 | 1.4286 | 1.6033 |
| Uracil_HMDB0000300 | 1.0053 | 1.0472 | 1.0460 | 1.0099 | 1.0565 | 0.9886 | 1.2903 | 1.1266 | 1.1780 | 1.2374 | 1.1613 | 1.1548 | 0.7393 | 0.7892 | 0.8326 | 0.7458 | 0.7257 | 0.8655 |
| Urea_HMDB0000294 | 0.9506 | 0.9041 | 0.8765 | 0.9315 | 0.9431 | 0.8837 | 0.8029 | 0.7049 | 0.7680 | 0.7939 | 0.7469 | 0.7138 | 1.2751 | 1.2579 | 1.4147 | 1.3241 | 1.2917 | 1.4165 |
| Uric acid_HMDB0000289 | 0.7920 | 0.8124 | 0.8425 | 1.0233 | 0.8333 | 0.5556 | 1.1472 | 1.0462 | 1.0826 | 0.8527 | 0.6642 | 0.9788 | 1.4312 | 1.0296 | 1.3298 | 1.1648 | 1.1290 | 1.2850 |
| Uridine_HMDB0000296 | 1.2568 | 1.0905 | 1.0489 | 0.9954 | 1.0476 | 0.9723 | 1.2119 | 0.8944 | 1.2889 | 1.0202 | 0.8300 | 0.9074 | 0.9736 | 0.7150 | 0.8844 | 0.8090 | 0.9691 | 1.0845 |
| Valine_HMDB0000883 | 0.9672 | 0.9617 | 0.9793 | 1.0317 | 1.0143 | 0.9867 | 0.7344 | 0.6264 | 0.6699 | 0.7144 | 0.6556 | 0.6640 | 1.2254 | 1.2293 | 1.4232 | 1.3765 | 1.3000 | 1.4400 |
| Xanthine_HMDB0000292 | 0.8564 | 0.6655 | 1.1001 | 1.0680 | 1.0352 | 0.9874 | 1.0582 | 0.5190 | 0.7595 | 0.7604 | 0.5253 | 0.8872 | 1.2296 | 0.9994 | 1.2202 | 1.6255 | 1.4342 | 1.2690 |
| Xanthylic acid_HMDB0001554 | 1.1211 | 0.7168 | 1.0903 | 0.8708 | 1.0435 | 0.7246 | 1.0941 | 0.7744 | 0.9878 | 0.5847 | 0.4918 | 0.7769 | 1.3814 | 0.9123 | 1.2817 | 1.4627 | 1.4045 | 1.2805 |
| Xylitol_HMDB0002917 | 1.5207 | 1.2516 | 1.4100 | 1.4541 | 1.7649 | 1.4765 | 0.6674 | 0.5813 | 0.6211 | 0.8424 | 0.6521 | 0.4582 | 0.9781 | 0.7880 | 0.7246 | 0.8353 | 0.8052 | 1.1685 |
| Xylose_HMDB0000098 | 1.0782 | 1.5422 | 0.6719 | 0.4826 | 0.9131 | 0.4262 | 0.7897 | 1.4130 | 1.8754 | 0.6190 | 0.2872 | 0.8798 | 0.8981 | 1.7592 | 1.0563 | 1.1634 | 1.3980 | 0.7466 |
| Xylulose_HMDB0001644 | 1.3092 | 0.6510 | 0.8564 | 1.3736 | 1.5597 | 2.3320 | 0.7870 | 0.5725 | 0.8790 | 1.3083 | 1.3606 | 0.6066 | 1.4178 | 0.2453 | 0.3917 | 0.6000 | 0.5114 | 1.2381 |
Factors:
| F1 | Sample source:SDHBKO_001 | Treatment:Knock out |
| F2 | Sample source:SDHBKO_002 | Treatment:Knock out |
| F3 | Sample source:SDHBKO_003 | Treatment:Knock out |
| F4 | Sample source:SDHBKO_004 | Treatment:Knock out |
| F5 | Sample source:SDHBKO_005 | Treatment:Knock out |
| F6 | Sample source:SDHBKO_006 | Treatment:Knock out |
| F7 | Sample source:UQCRC1KO_001 | Treatment:Knock out |
| F8 | Sample source:UQCRC1KO_002 | Treatment:Knock out |
| F9 | Sample source:UQCRC1KO_003 | Treatment:Knock out |
| F10 | Sample source:UQCRC1KO_004 | Treatment:Knock out |
| F11 | Sample source:UQCRC1KO_005 | Treatment:Knock out |
| F12 | Sample source:UQCRC1KO_006 | Treatment:Knock out |
| F13 | Sample source:Wild type_001 | Treatment:Control |
| F14 | Sample source:Wild type_002 | Treatment:Control |
| F15 | Sample source:Wild type_003 | Treatment:Control |
| F16 | Sample source:Wild type_004 | Treatment:Control |
| F17 | Sample source:Wild type_005 | Treatment:Control |
| F18 | Sample source:Wild type_006 | Treatment:Control |