Data for Murine gut bile acid analysis (Study ST000212)

(Analysis AN000314)

Values for each metabolite have been scaled by dividing by the mean across all factors

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Metabolite	F1	F2	F3	F4	F5	F6	F7	F8	F9	F10	F11	F12
?a-Muricholic acid	0.0055	0.1194	0.0017	0.1470	0.0167	0.1136	0.0223	3.2926	0.0245	6.6746	0.0047	0.7250
b-Muricholic acid	0.0003	0.3245	0.0003	0.2950	0.0132	0.4466	0.0081	4.1650	0.0098	6.0669	0.0004	0.4700
Chenodeoxycholic acid	0.0499	NA	0.0300	NA	0.2330	0.8706	0.2572	3.0628	0.1908	4.2176	0.0624	NA
Cholic acid	0.0479	0.0366	0.0303	0.0833	0.2287	0.6573	0.4566	3.9958	0.3275	5.7954	0.0366	0.1300
Deoxycholic acid	NA	1.1775	NA	1.4269	NA	0.1442	NA	0.2959	NA	0.4402	NA	2.5402
Glychocholic acid	0.0203	0.0204	0.0238	0.0205	0.4891	2.6978	0.3707	4.0105	0.6821	3.5899	0.0232	0.0517
Glycochenodeoxycholic acid	0.5008	0.5150	0.6085	0.5188	1.2706	1.5758	0.9846	1.2443	1.4842	1.3590	0.5831	1.3553
Glycodeoxycholic acid	0.4410	0.5556	0.5563	0.5766	0.4375	2.2266	0.2904	1.9723	0.3680	2.7295	0.5123	1.3340
GLYCO-HYODEOXYCHOLIC ACID/GLYCOURSODEOXYCHOLIC ACID	0.3486	0.3630	0.4299	0.3600	1.9386	1.3709	1.7202	0.8332	2.4069	0.8777	0.4112	0.9399
Glycolithocholic acid	0.4834	0.9740	0.7397	1.5074	0.8701	1.2494	0.5000	1.2705	0.9669	0.6802	0.5996	2.3234
g-Muricholic acid (hyocholic acid)	0.0066	0.1156	0.0081	0.2030	0.0066	0.1125	0.0281	3.9447	0.0055	7.2898	0.0077	0.2717
Hyodeoxycholic acid	NA	1.9361	0.0018	1.7304	0.0187	0.3106	0.0197	1.1045	0.0206	1.2293	0.0028	3.2957
Lithocholic acid	0.0492	2.7832	0.0688	2.8498	0.0618	0.1355	0.0368	0.1238	0.0456	0.0818	0.0575	5.7063
Taurochenodeoxycholic acid	0.0524	0.0073	0.0429	0.0083	2.6330	1.6627	2.0553	1.3451	2.9248	1.2077	0.0451	0.0154
Taurocholic acid	1.5546	0.0764	1.1374	0.0786	NA	NA	NA	NA	NA	10.2933	1.0276	0.0835
Taurodeoxycholic acid	0.0138	0.0865	0.0170	0.1562	0.0139	4.4452	0.0092	3.0005	0.0117	3.9398	0.0163	0.2900
Taurolithocolic acid	0.3158	0.4234	0.3876	0.4385	0.7334	2.3836	0.5210	2.5269	0.7392	2.0817	0.3788	1.0701
Tauroursodeoxycholic acid/Tauro-hyodeoxycholic acid	1.6967	0.2481	1.3588	0.5381	NA	NA	NA	NA	NA	NA	1.3717	0.5024
w-Muricholic acid	NA	0.5912	NA	0.5361	0.0035	0.2044	0.0230	2.4699	0.0072	4.1711	NA	0.9919

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Factors:

F1	GI tract location:cecum | treatment:cefoperazone
F2	GI tract location:cecum | treatment:vehicle
F3	GI tract location:colon | treatment:cefoperazone
F4	GI tract location:colon | treatment:vehicle
F5	GI tract location:duodenum | treatment:cefoperazone
F6	GI tract location:duodenum | treatment:vehicle
F7	GI tract location:ileum | treatment:cefoperazone
F8	GI tract location:ileum | treatment:vehicle
F9	GI tract location:jejunum | treatment:cefoperazone
F10	GI tract location:jejunum | treatment:vehicle
F11	GI tract location:stool | treatment:cefoperazone
F12	GI tract location:stool | treatment:vehicle