Data for Analysis of DJ-1 Knockout Mouse Brains (Study ST000260)

(Analysis AN000414)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4
10-heptadecenoate (17:1n7) 1.0291 0.9152 1.1256 0.9370
10-nonadecenoate (19:1n9) 0.9601 1.0250 1.1898 0.8720
15-HETE 1.0210 0.9881 1.0337 0.9664
1-arachidonoylglycerophosphocholine (20:4n6)* 0.9702 1.1150 1.0270 0.9302
1-arachidonoylglycerophosphoethanolamine* 1.0287 1.0916 1.0701 0.8687
1-arachidonoylglycerophosphoinositol* 1.1499 0.8876 1.0113 0.9494
1-docosahexaenoylglycerol (1-monodocosahexaenoin) 0.9497 0.9952 1.1809 0.9051
1-docosahexaenoylglycerophosphoethanolamine* 0.9814 1.0238 1.1000 0.9241
1-oleoylglycerophosphoethanolamine 0.9769 1.0040 1.0776 0.9567
1-oleoylglycerophosphoglycerol* 1.0161 1.0805 1.1842 0.7995
1-oleoylglycerophosphoinositol* 1.0528 1.0015 1.0766 0.9020
1-oleoylglycerophosphoserine 0.9156 1.0533 1.1569 0.9123
1-oleoylplasmenylethanolamine* 0.8696 1.0874 0.9860 1.0537
1-palmitoylglycerophosphoethanolamine 0.9704 1.0511 1.0989 0.9160
1-palmitoylglycerophosphoglycerol* 1.0731 1.1369 1.0738 0.8043
1-palmitoylglycerophosphoinositol* 1.1064 0.8976 0.9713 1.0058
1-palmitoylplasmenylethanolamine* 0.9175 0.9559 1.0735 1.0343
1-stearoylglycerophosphoethanolamine 0.9256 1.0409 1.0776 0.9720
1-stearoylglycerophosphoinositol 1.0067 0.9031 1.1633 0.9331
1-stearoylglycerophosphoserine* 0.9784 0.9457 1.1044 0.9718
1-stearoylplasmenylethanolamine* 0.9164 0.8874 1.0420 1.1016
2-arachidonoylglycerophosphoethanolamine* 0.9083 1.0650 1.0984 0.9543
2-arachidonoylglycerophosphoinositol* 1.1553 0.9067 1.0324 0.9175
2-docosahexaenoylglycerophosphoethanolamine* 0.9349 0.9944 1.1617 0.9310
2-hydroxypalmitate 1.0118 0.9638 1.1080 0.9328
2-hydroxystearate 1.0188 0.9657 1.1342 0.9067
2-oleoylglycerophosphoethanolamine* 0.9643 1.0531 1.0964 0.9213
2-oleoylglycerophosphoglycerol* 1.1011 1.1412 1.0440 0.8030
2-oleoylglycerophosphoserine* 0.9783 0.9400 1.2661 0.8515
2-palmitoylglycerophosphoethanolamine* 0.9338 1.0274 1.1702 0.9049
2-stearoylglycerophosphoinositol* 0.9950 0.8000 1.1299 1.0358
3-(4-hydroxyphenyl)lactate 0.9107 1.1952 0.9547 0.9790
3^-dephosphocoenzyme A 1.0958 0.8981 1.0724 0.9376
3-indoxyl sulfate 1.1210 1.3096 1.0109 0.7075
5-HETE 1.1094 0.9278 0.9790 0.9789
5-oxoproline 1.0207 1.0571 1.0005 0.9484
acetyl CoA 1.2710 0.9379 0.8730 0.9150
adenosine 5^diphosphoribose 1.0518 1.0217 0.8321 1.0735
adenylosuccinate 0.9876 1.0645 0.8061 1.1144
adrenate (22:4n6) 1.1669 0.7515 0.9928 1.0355
anserine 0.8688 0.9188 1.1545 1.0333
arachidonate (20:4n6) 1.0876 0.9500 1.0044 0.9622
beta-muricholate NA NA 1.3308 0.6692
carnosine 0.9498 0.9813 1.0277 1.0285
coenzyme A 1.0007 0.9915 1.0289 0.9831
dihomo-linoleate (20:2n6) 0.9898 0.9286 1.1138 0.9669
dihomo-linolenate (20:3n3 or n6) 0.9356 0.9411 1.0749 1.0289
dihydroxyacetone phosphate (DHAP) 0.8398 1.0747 0.8188 1.2094
docosahexaenoate (DHA; 22:6n3) 1.0846 0.8825 1.0581 0.9664
docosapentaenoate (n3 DPA; 22:5n3) 1.0348 0.8494 1.1307 0.9700
docosapentaenoate (n6 DPA; 22:5n6) 1.0941 1.0971 1.0421 0.8274
eicosapentaenoate (EPA; 20:5n3) 0.8856 0.6547 1.1199 1.2116
eicosenoate (20:1n9 or 11) 1.0054 1.0343 1.0312 0.9512
flavin adenine dinucleotide (FAD) 1.0028 0.9899 1.0131 0.9944
guanosine 5^-diphospho-fucose 1.1114 0.9961 1.0111 0.9105
histidine 1.0058 1.1392 0.8815 0.9975
homocarnosine 0.8602 1.0259 1.0039 1.0858
hypoxanthine 1.0073 1.0457 1.0068 0.9608
inosine 1.0388 1.0333 0.9761 0.9680
Isobar: fructose 1,6-diphosphate, glucose 1,6-diphosphate, myo-inositol 1,4 or 1,3-diphosphate 0.8313 1.0986 0.8600 1.1699
linoleate (18:2n6) 0.9347 0.8476 1.1330 1.0444
linolenate [alpha or gamma; (18:3n3 or 6)] 0.8690 0.6377 1.2066 1.1698
margarate (17:0) 0.9783 0.9616 1.0975 0.9671
mead acid (20:3n9) 0.9204 0.9014 1.1395 1.0167
myo-inositol hexakisphosphate 0.9980 1.0094 1.0078 0.9895
N-acetylmethionine 0.9183 1.0299 0.9362 1.0905
N-oleoyltaurine 0.9631 1.0811 1.0941 0.9064
N-palmitoyltaurine 1.0713 0.9617 1.0864 0.9057
N-stearoyltaurine 0.9025 0.9857 1.0806 1.0216
oleic ethanolamide 1.0567 0.9435 1.0012 0.9919
palmitate (16:0) 1.0117 0.9994 1.0235 0.9739
palmitoleate (16:1n7) 0.9929 0.8267 1.1078 1.0328
palmitoyl ethanolamide 1.0553 1.0388 1.0126 0.9248
phenol sulfate 0.9111 0.8412 1.2974 0.9429
phosphoethanolamine 1.0054 1.0350 0.9701 0.9965
prostaglandin D2 0.9914 0.8816 1.1072 1.0000
prostaglandin E2 0.9962 0.9422 1.0343 1.0132
pseudouridine 1.0039 0.9976 1.0063 0.9938
S-adenosylhomocysteine (SAH) 1.0436 1.0065 1.0613 0.9173
stearate (18:0) 1.0088 1.0198 1.0195 0.9664
succinate 0.9928 0.9931 1.0186 0.9958
sucrose 2.3388 0.4897 0.8843 0.6243
tauro(alpha + beta)muricholate NA NA 0.1803 1.8197
taurocholate 0.2009 0.2182 0.2869 3.6507
uridine 1.0101 0.9937 0.9752 1.0150
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Factors:

F1Sex:F | Genotype:DJ-1 Knockout
F2Sex:F | Genotype:WT
F3Sex:M | Genotype:DJ-1 Knockout
F4Sex:M | Genotype:WT
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