Data for (Study ST000282)

(Analysis AN000449)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7F8F9F10F11F12F13F14
2 or 3-phosphoglycerate_13C_1 0.2181 1.2542 0.0375 NA NA 0.6069 1.4221 0.7852 1.3426 0.5545 0.7917 NA 2.0713 1.1512
2 or 3-phosphoglycerate_13C_2 0.2586 NA 0.8980 NA 0.4135 NA 3.0809 NA 0.2446 NA 0.6122 0.5570 0.4917 0.3624
2 or 3-phosphoglycerate_13C_3 0.1105 0.0734 0.0736 0.0678 NA 0.0772 4.9598 1.8494 0.2347 0.0719 1.3841 0.3924 0.4184 0.0924
2 or 3-phosphoglycerate_2PG/3PG 1.3415 0.4573 1.1246 0.6995 3.0990 1.7562 0.4923 0.3201 1.9105 0.2837 0.2449 0.1687 1.2958 0.4031
3-Glycerophosphate 0.4844 0.1787 0.3480 0.1648 0.8860 0.3699 1.2419 1.3138 2.5214 3.1425 0.3332 0.1763 0.7577 0.3182
3-Glycerophosphate_13C_1 0.4187 0.1726 0.0408 0.0957 0.2266 0.1163 5.4455 0.2984 0.2054 0.8525 1.5635 0.7052 0.1275 0.0802
3-Glycerophosphate_13C_2 NA NA NA NA NA NA NA 1.0000 NA NA NA NA NA NA
3-Glycerophosphate_13C_3 NA NA NA NA NA NA NA NA NA NA NA NA NA NA
3-phosphoglyceraldehyde 2.3491 1.3813 0.5271 1.2361 3.5118 0.8903 0.4962 0.4655 1.2461 0.6223 0.4083 0.2268 0.5699 0.3269
3-phosphoglyceraldehyde_13C_1 NA NA NA NA NA NA 2.4164 0.2191 NA 0.0682 2.0751 1.1412 0.0799 NA
3-phosphoglyceraldehyde_13C_2 NA NA NA NA NA NA NA NA NA NA NA NA NA NA
3-phosphoglyceraldehyde_13C_3 NA NA NA NA NA NA 0.8688 2.2845 NA 0.4274 0.8329 0.5864 NA NA
6-Phosphogluconate 0.2898 0.4033 0.5594 0.7178 4.3223 0.5767 1.4850 0.3344 2.1443 0.3153 0.2676 0.2030 0.4726 0.2796
6-Phosphogluconate_13C_1 NA NA NA NA NA NA NA NA 1.0000 NA NA NA NA NA
6-Phosphogluconate_13C_2 NA NA NA NA 1.1571 NA NA NA 0.8429 NA NA NA NA NA
6-Phosphogluconate_13C_3 0.4031 0.5611 NA NA NA NA 2.0659 0.4653 NA 0.4386 NA NA NA NA
6-Phosphogluconate_13C_4 0.0038 0.0052 NA NA NA NA 0.0193 6.9274 0.0209 0.0041 NA NA NA NA
6-Phosphogluconate_13C_5 1.8463 0.6356 NA NA 2.4520 NA 0.5589 NA 0.4741 NA NA NA NA NA
6-Phosphogluconate_13C_6 NA NA NA NA NA NA 1.0418 1.6649 NA 0.2516 NA NA NA NA
Acetyl-CoA 0.7317 0.8059 0.3892 0.3243 2.7748 0.5482 0.8109 NA 1.0738 2.7896 NA NA 0.5160 0.3508
Acetyl-CoA_13C_1 NA NA NA NA 0.1181 NA NA NA 1.8819 NA NA NA NA NA
Acetyl-CoA_13C_2 NA NA NA NA NA NA 1.0000 NA NA NA NA NA NA NA
Adenosine diphosphate_13C_1 0.2288 0.7604 1.0061 0.8279 2.4694 1.0286 0.5854 2.9746 0.5410 1.7724 0.2461 NA 0.6408 0.3332
Adenosine diphosphate_13C_2 0.3240 0.5212 0.3000 0.4805 0.5778 0.7010 1.6770 6.8430 0.3171 1.2132 0.4635 0.2888 0.2770 0.0218
Adenosine diphosphate_13C_3 NA NA NA NA NA NA 0.5508 3.3295 NA 0.3398 0.2290 NA NA NA
Adenosine diphosphate_13C_4 NA NA NA NA NA NA 0.2559 1.7441 NA NA NA NA NA NA
Adenosine diphosphate_13C_5 NA 0.0198 0.1060 0.0466 NA NA 0.7743 8.6360 0.0500 0.2511 0.1904 0.0882 0.0634 NA
Adenosine monophosphate_13C_1 1.2129 0.2790 2.4835 0.6168 2.4133 0.4199 1.2508 0.8966 0.8933 1.3882 1.2092 0.1286 0.4168 0.1401
Adenosine monophosphate_13C_2 0.7238 NA 0.6984 0.2304 NA NA 0.7430 2.8545 NA 0.7498 NA NA NA NA
Adenosine monophosphate_13C_3 1.1780 0.5483 NA NA NA NA NA 1.9282 1.0508 1.2431 NA 0.0008 NA NA
Adenosine monophosphate_13C_4 NA NA NA NA NA NA 0.0015 3.9953 NA NA 0.0019 0.0013 NA NA
Adenosine monophosphate_13C_5 NA NA 0.0813 NA NA NA 0.2401 6.1117 NA 0.0989 0.1294 0.0986 NA NA
Adenosine triphosphate_13C_1 NA NA 1.2701 0.0831 NA NA 1.2008 1.4242 2.0537 0.4372 0.4360 0.0940 1.1831 0.5634
Adenosine triphosphate_13C_2 NA NA NA 0.0767 0.7279 0.8805 3.5028 2.3577 0.4060 0.2299 0.5043 0.2344 0.0816 0.0896
Adenosine triphosphate_13C_3 0.8932 0.5354 0.3612 0.0391 0.7035 0.4326 3.3076 3.8611 0.3597 0.1819 0.4384 0.1649 0.2633 0.1505
Adenosine triphosphate_13C_4 0.8698 0.2644 NA 0.0848 0.3584 0.1929 2.5036 5.6365 0.2860 0.2733 0.4446 0.0669 0.2290 NA
Adenosine triphosphate_13C_5 0.0610 0.0744 0.0873 0.0471 0.0160 0.0352 4.0255 6.5150 0.0831 0.1426 0.4167 0.1130 0.2513 0.0232
ADP 1.4124 4.0887 1.0495 0.9546 2.4475 1.1224 0.4764 0.3905 0.9409 0.6641 0.2716 0.1876 0.3369 0.2395
AMP 2.2120 4.9088 0.9415 2.0673 1.5825 0.6219 0.2634 0.3121 0.4540 1.0863 0.1666 0.1929 0.3045 0.1689
Aspartate 1.5764 1.6047 0.9601 0.7021 1.1277 0.8613 2.4603 1.6970 0.9696 0.3159 0.0832 0.0724 0.0968 0.0426
Aspartate_13C_1 NA 1.9841 NA NA NA NA 0.4071 3.1490 NA NA 0.0068 0.0460 NA NA
Aspartate_13C_2 2.4113 2.1685 0.7887 0.5028 0.6089 0.4723 0.7654 3.2699 1.8282 0.2480 0.0611 0.0700 0.1421 0.0692
Aspartate_13C_3 1.3539 0.9316 0.6743 0.4676 0.6991 0.8395 0.9681 2.2625 2.9639 0.2186 0.1246 0.1468 0.2781 0.1391
Aspartate_13C_4 2.3393 1.9780 0.9616 0.5995 1.4493 0.9880 0.0124 0.2016 3.4693 0.2322 0.0134 0.0164 0.2017 0.0553
ATP 3.8842 2.0528 1.0193 0.3613 2.6846 1.4821 0.5545 0.1263 1.1721 0.0945 0.1435 0.1262 0.4286 0.1435
Citrate or Isocitrate 0.7485 0.6788 1.3153 1.4671 1.3586 1.1723 1.0531 1.0030 0.8870 0.9655 1.1419 0.8565 0.8328 0.5794
Citrate or Isocitrate_13C_1 1.9250 1.3797 1.3688 1.7020 0.3491 0.6538 0.2945 1.3493 0.7232 1.5300 0.4272 0.6991 1.2235 0.6513
Citrate or Isocitrate_13C_2 1.0432 0.6759 0.8094 1.0088 0.5171 0.4532 1.0174 3.6684 0.6146 0.6226 1.4560 1.3075 0.7423 0.4317
Citrate or Isocitrate_13C_3 1.0608 0.5585 0.7000 0.9119 0.8987 1.1406 0.2825 2.2341 1.1427 0.8273 0.7612 0.7653 2.3578 0.9335
Citrate or Isocitrate_13C_4 1.5468 1.0862 1.3720 1.5536 2.0394 1.5443 0.1589 0.8971 1.3554 0.6591 0.3681 0.4671 0.9778 0.4599
Citrate or Isocitrate_13C_5 0.4527 0.4779 0.4472 0.6603 0.6467 1.1066 0.1433 0.9295 1.2848 0.7266 0.4263 0.3686 5.3367 1.5648
Citrate or Isocitrate_13C_6 0.5238 0.4228 0.7287 0.8356 1.7235 0.8275 0.8015 2.2903 0.9949 0.9279 1.0184 1.2237 1.2498 0.6352
Erythrose 4-phosphate 2.6110 NA NA 0.0680 1.9014 0.5246 NA NA 0.7743 NA 0.1206 NA NA NA
Erythrose 4-phosphate_13C_1 NA NA NA NA 1.0000 NA NA NA NA NA NA NA NA NA
Erythrose 4-phosphate_13C_2 NA NA 0.8634 NA 0.7968 0.9537 0.9720 NA 0.6857 2.1169 0.5303 0.6941 1.3492 1.0658
Erythrose 4-phosphate_13C_3 NA NA NA NA NA NA 1.2132 1.1194 NA NA 0.4542 NA NA NA
Erythrose 4-phosphate_13C_4 NA NA NA NA NA NA NA 1.0000 NA NA NA NA NA NA
Fructose 1,6-bisphosphate 2.6283 1.7455 1.0689 0.8125 3.2602 0.8759 0.4980 0.2546 1.3502 0.3241 0.2059 0.3148 0.5618 0.2512
Fructose 1,6-bisphosphate_13C_1 1.8708 NA NA 1.3437 3.8047 0.7157 0.0956 0.6443 0.4634 NA NA NA 0.5029 NA
Fructose 1,6-bisphosphate_13C_2 2.9130 0.6116 0.5661 NA NA 1.0937 0.7933 NA 0.9340 NA NA NA 0.2950 NA
Fructose 1,6-bisphosphate_13C_3 NA NA NA NA NA NA 1.9122 0.1699 NA NA 0.0056 NA NA NA
Fructose 1,6-bisphosphate_13C_4 NA NA NA 2.1678 NA NA NA NA NA 0.7850 0.4285 NA NA 0.6187
Fructose 1,6-bisphosphate_13C_5 NA 0.0057 0.0034 0.0017 0.0120 NA 2.7455 5.4784 0.0053 0.0003 NA NA 0.0022 0.0003
Fructose 1,6-bisphosphate_13C_6 NA 0.0949 0.2336 0.1770 0.1300 NA 2.8451 4.4135 0.2810 0.4303 0.2182 NA 0.2854 0.0458
Glucose 6-phosphate or fructose-6-phosphate 1.4643 0.9347 1.1742 1.8344 2.9445 0.7102 0.4049 NA 1.3788 0.3229 0.2176 0.1967 1.3309 0.3023
Glucose 6-phosphate or fructose-6-phosphate_13C_1 0.7456 NA 2.8499 0.6305 1.9495 0.2406 0.0720 NA 1.2297 0.6756 0.7864 NA 0.8310 0.7596
Glucose 6-phosphate or fructose-6-phosphate_13C_2 0.1944 0.2329 NA 0.6733 NA NA 0.2292 1.3012 0.2321 6.0546 0.6905 NA 0.8880 0.2718
Glucose 6-phosphate or fructose-6-phosphate_13C_3 NA NA NA NA NA NA 2.1726 NA NA 0.5003 1.3100 0.0171 NA NA
Glucose 6-phosphate or fructose-6-phosphate_13C_4 NA NA 0.0430 NA NA 0.0207 NA NA NA NA NA 2.9363 NA NA
Glucose 6-phosphate or fructose-6-phosphate_13C_5 0.0042 0.0026 0.0033 NA 0.0070 0.0008 4.6288 0.0044 0.0053 NA 2.0139 1.6923 0.0064 0.0022
Glucose 6-phosphate or fructose-6-phosphate_13C_6 0.0618 0.1093 0.1070 NA 0.2083 0.2609 3.5952 2.4501 0.2364 0.1430 1.6828 1.2562 0.1393 0.1544
Glutamate 1.1602 0.9689 0.8861 0.7096 0.8064 0.6634 2.3790 3.2057 0.6049 0.8179 0.2573 0.2114 0.1912 0.1543
Glutamate_13C_1 2.6193 2.2913 1.1380 0.6825 0.3984 0.3048 0.1921 3.3134 0.7143 2.9069 0.0839 0.0597 0.2223 0.1668
Glutamate_13C_2 1.0436 0.7714 0.4094 0.3159 0.2550 0.2377 1.0567 8.1997 0.4641 0.9633 0.2420 0.2804 0.1390 0.1011
Glutamate_13C_3 2.6046 1.8894 1.2928 0.9061 1.2235 0.9867 0.0841 1.5706 1.5439 1.6689 0.0391 0.0659 0.3126 0.1839
Glutamate_13C_4 0.8941 0.5730 0.4957 0.3519 0.9327 0.7172 0.1458 5.5228 1.2828 1.4024 0.0998 0.1531 NA NA
Glutamate_13C_5 1.7207 1.1246 1.1428 0.7183 2.1042 1.5046 0.0054 0.1188 2.5024 2.0974 0.0045 0.0105 0.3022 0.1357
Lactate 1.3461 0.8932 0.8801 0.6085 1.6839 0.7606 0.6814 0.7706 1.1229 2.4783 0.5643 0.5338 1.3110 0.5610
Lactate_13C_1 0.4486 0.3734 1.7712 0.9798 NA 0.1333 1.5182 2.5146 0.1467 NA 2.0508 1.0359 0.3040 0.2055
Lactate_13C_2 0.0846 0.0691 0.1444 NA NA 0.0803 1.0317 8.6767 0.0430 0.4992 1.1479 0.7586 0.3370 0.0529
Lactate_13C_3 0.0225 0.0140 0.0332 0.0224 0.0073 0.0054 1.2625 11.2987 0.0084 0.0790 1.1404 0.8060 0.0242 0.0050
Malate 1.1039 0.8398 1.1951 1.2029 1.4868 1.0265 1.4992 1.2907 0.5002 0.4197 1.5707 1.0486 0.1992 0.6173
Malate_13C_1 2.2317 1.6371 0.6003 0.9179 0.5506 0.2871 0.2619 2.0200 0.6412 0.4429 0.8269 1.1533 2.2783 1.2480
Malate_13C_2 1.7228 1.1497 0.9656 0.9193 0.8038 0.6749 0.4765 2.5308 0.8179 0.6276 1.6231 1.0875 0.3745 0.9317
Malate_13C_3 0.8524 0.8371 0.3796 0.4013 0.7395 0.5780 0.5372 1.9193 1.8165 0.4456 1.8747 1.5624 0.4313 1.2712
Malate_13C_4 1.7579 1.1105 1.0578 0.8643 2.1442 1.1881 0.0594 0.2195 1.8281 0.7620 0.0911 0.1272 1.9020 1.0003
Malonyl-CoA 0.9203 0.7538 1.1513 1.0791 1.3124 1.0819 1.0316 1.2086 1.0620 0.9265 0.8117 0.8829 1.0129 0.6716
Malonyl-CoA_13C_1 1.0000 NA NA NA NA NA NA NA NA NA NA NA NA NA
Malonyl-CoA_13C_2 NA NA NA NA NA NA NA NA NA NA NA NA NA NA
Malonyl-CoA_13C_3 NA NA NA NA NA NA NA NA NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide oxidized 1.2513 1.2771 1.0204 0.8377 1.0646 0.6850 0.6947 NA 1.3004 0.8094 0.6663 0.3251 2.1652 0.9079
Nicotinamide Adenine Dinucleotide oxidized_13C_1 1.5194 1.1023 1.9492 NA NA 1.2851 0.2624 NA 0.5758 1.7544 0.6407 0.3574 0.9638 0.5895
Nicotinamide Adenine Dinucleotide oxidized_13C_2 0.0165 0.2299 0.0502 NA 0.0761 0.1883 2.6509 1.7563 0.8285 0.9228 2.6518 1.0779 0.4884 0.5829
Nicotinamide Adenine Dinucleotide oxidized_13C_3 NA 0.2950 NA NA NA NA 1.0917 NA NA 1.0366 2.0277 1.1915 0.2658 NA
Nicotinamide Adenine Dinucleotide oxidized_13C_4 NA NA NA NA NA NA NA 1.3124 NA NA 0.9920 0.6956 NA NA
Nicotinamide Adenine Dinucleotide oxidized_13C_5 NA NA NA NA NA NA 0.9674 0.6822 NA NA 1.4034 0.9797 NA NA
Nicotinamide Adenine Dinucleotide reduced 4.9448 0.4724 0.3082 0.0672 4.4559 0.7995 0.2955 NA 0.5957 0.2608 0.0434 0.0404 0.1205 NA
Nicotinamide Adenine Dinucleotide reduced_13C_1 0.0956 0.5443 NA NA 1.1709 1.9653 0.2834 1.9405 1.2550 0.4901 NA NA NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_2 NA 0.1998 NA NA 1.8002 NA NA NA NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_3 1.5721 NA NA NA 0.7344 NA 0.0397 1.6537 NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_4 NA NA NA NA NA NA 0.0099 1.9901 NA NA NA NA NA NA
Nicotinamide Adenine Dinucleotide reduced_13C_5 NA NA NA NA NA NA 1.4906 0.5094 NA NA NA NA NA NA
Phosphoenolpyruvate 0.7167 0.4185 1.3393 1.4467 1.9654 1.9556 0.3949 NA 1.6081 0.1127 0.3677 0.2985 1.8681 0.5049
Phosphoenolpyruvate_13C_1 NA NA 0.0994 NA 2.3047 NA 1.3260 NA NA NA NA NA NA 0.2699
Phosphoenolpyruvate_13C_2 NA NA 0.5515 NA 0.7320 NA 1.3198 1.6642 NA NA 1.1353 0.6783 0.5991 NA
Phosphoenolpyruvate_13C_3 NA NA NA NA NA NA 2.1077 0.1783 0.0823 NA 1.5407 0.9183 0.0650 NA
Ribose-5-phosphate or xylulose 5-phosphate 0.5267 0.4501 1.1542 1.0972 2.2080 0.9515 0.4007 0.0436 3.4338 0.3547 0.1059 0.0395 0.7034 0.6959
Ribose-5-phosphate or xylulose 5-phosphate_13C_1 NA 0.2975 1.7768 1.2094 3.0656 0.4490 1.2137 NA 0.6318 0.3686 NA NA 0.4251 0.3487
Ribose-5-phosphate or xylulose 5-phosphate_13C_2 0.2612 NA NA 0.1178 NA NA 2.6255 NA 0.5406 0.2889 NA NA NA NA
Ribose-5-phosphate or xylulose 5-phosphate_13C_3 NA NA NA NA NA NA NA 0.0015 NA NA 2.9971 0.0014 NA NA
Ribose-5-phosphate or xylulose 5-phosphate_13C_4 NA NA NA NA NA NA NA 1.0494 NA NA NA 0.9506 NA NA
Ribose-5-phosphate or xylulose 5-phosphate_13C_5 NA NA NA NA NA NA 1.9379 0.3706 NA NA 0.3857 0.3678 NA NA
Sedoheptulose 7-phosphate 0.6011 0.3938 1.1412 0.8360 2.0985 0.8699 0.2787 0.2177 2.1994 2.0142 0.1638 0.1235 1.5818 1.0021
Sedoheptulose 7-phosphate_13C_1 0.1411 0.8054 NA 0.4557 2.2743 NA NA NA 0.9697 NA NA NA NA 1.3841
Sedoheptulose 7-phosphate_13C_2 NA NA NA NA 1.2118 NA 1.5225 NA 0.3147 0.8517 0.5769 NA NA NA
Sedoheptulose 7-phosphate_13C_3 NA NA 0.0019 NA NA NA 2.4922 0.0087 NA NA NA 0.0050 NA NA
Sedoheptulose 7-phosphate_13C_4 NA NA 1.0151 NA 0.8176 NA 1.8856 1.1238 0.5637 NA 0.8620 0.8441 NA 0.0024
Sedoheptulose 7-phosphate_13C_5 NA NA NA NA NA NA 1.8160 NA NA NA 0.7658 0.4085 NA 0.1939
Sedoheptulose 7-phosphate_13C_6 NA NA NA NA NA NA 0.9006 1.8397 NA NA NA 0.2597 NA NA
Sedoheptulose 7-phosphate_13C_7 NA NA NA NA NA NA 1.2898 1.4164 NA NA 0.5960 0.4080 NA NA
Sucrose 0.8318 0.6732 1.0590 0.5101 1.0640 1.0073 1.2396 1.4688 1.1388 2.1872 0.7130 0.7825 0.3372 0.6091
Sucrose_13C_1 1.2139 0.7478 0.2736 0.2983 0.3751 0.3563 0.3300 1.3448 1.1272 1.1461 1.1636 0.7346 4.1867 1.2447
Sucrose_13C_2 NA NA NA NA NA NA NA NA NA NA NA NA NA NA
Sucrose_13C_3 NA NA NA NA NA NA NA NA NA NA NA NA NA NA
Sucrose_13C_4 1.5671 0.9290 0.3261 0.7546 0.7372 0.4740 NA 0.1157 0.8054 3.7062 NA NA 1.1575 0.6220
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Factors:

F1Cell line:MCF10A  | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F2Cell line:MCF10A  | 13C Label:Glutamine | RhoC overexpression:yes | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F3Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F4Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:yes
F5Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:yes | RhoC drug:no
F6Cell line:MDA-MB-231 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:yes | RhoC knockdown:no | RhoC drug:no
F7Cell line:SUM149 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F8Cell line:SUM149 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:yes
F9Cell line:SUM149 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F10Cell line:SUM149 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:yes
F11Cell line:SUM190 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F12Cell line:SUM190 | 13C Label:Glucose | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:yes | RhoC drug:no
F13Cell line:SUM190 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:no | RhoC drug:no
F14Cell line:SUM190 | 13C Label:Glutamine | RhoC overexpression:no | RhoA knockdown:no | RhoC knockdown:yes | RhoC drug:no
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