Data for Effect of BCAT1 knockdown on amino acid steady state levels of Raji cells (Study ST000458)

(Analysis AN000719)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7
Alanine 0.8517 0.8210 0.9255 0.8803 1.6291 1.4394 0.4281
Arginine 0.8514 0.5062 1.3770 1.1058 2.4062 0.5390 0.3400
Asparagine 1.1359 0.8932 0.9427 0.9717 1.5023 1.0938 0.4414
Aspartate 1.3218 1.0153 NA NA 0.8549 0.7647 NA
Citrulline NA 0.7292 0.4599 0.3314 NA 2.1065 0.3701
Glutamate 1.2581 0.7940 1.1033 1.1776 1.2689 0.8043 0.6283
Glutamine 0.8795 1.1808 NA NA NA NA NA
Glycine 0.7690 0.5974 0.8399 0.8533 2.0054 1.5114 0.3702
Histidine 1.0780 0.7295 0.8889 0.9538 1.6000 1.3108 0.4021
Isoleucine 1.0104 0.6715 1.0161 0.8598 1.7384 1.3682 0.3409
Leucine 1.0284 0.6908 0.9502 0.9350 1.6934 1.3268 0.3588
Lysine NA NA NA NA 1.0947 0.9053 NA
Ornithine NA 0.7425 NA NA NA 1.0858 NA
Phenylalanine 1.0446 0.6981 0.8535 0.8798 1.6662 1.4149 0.3941
Proline 0.5950 0.6821 0.8449 0.7510 1.7530 1.9001 0.4221
Serine 1.6085 1.6293 0.6700 0.7449 0.8851 0.3919 NA
Threonine 1.1084 0.9662 0.9436 0.9340 1.1122 0.8835 NA
Tryptophan 0.9002 NA NA 1.2622 1.1261 0.8198 NA
Tyrosine 0.9016 0.5851 0.7238 0.9406 1.5199 1.0788 NA
Valine NA NA NA NA 1.1933 0.8067 NA
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Factors:

F1Time:144(hrs) | Treatment:Doxycycline
F2Time:144(hrs) | Treatment:Vehicle
F3Time:48(hrs) | Treatment:Doxycycline
F4Time:48(hrs) | Treatment:Vehicle
F5Time:96(hrs) | Treatment:Doxycycline
F6Time:96(hrs) | Treatment:Vehicle
F7Time:- | Treatment:Vehicle
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