Data for Metabolic changes to maternal rat liver tissue during and post-pregnancy (Study ST000509)
(Analysis AN000781)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 | F11 |
|---|---|---|---|---|---|---|---|---|---|---|---|
| 2-Oxoglutarate | 1.1095 | 1.0309 | 0.7946 | 0.8823 | 0.9615 | 0.9497 | 1.0690 | 0.8788 | 1.1003 | 1.1252 | 1.0237 |
| 3-Phospho-D-erythronate | 1.1201 | 1.0213 | 1.1888 | 1.0712 | 1.0545 | 0.9830 | 0.8692 | 0.9411 | 1.0343 | 0.7652 | 1.0082 |
| 3-Phosphonooxypyruvate | 1.3329 | 0.8619 | 0.7875 | 0.8371 | 0.8885 | 1.0593 | 0.8954 | 0.8555 | 1.4327 | 1.0757 | 0.9377 |
| 3-Sulfino-L-alanine | 0.8289 | 1.1365 | 1.0697 | 0.8836 | 0.8488 | 0.9359 | 1.0347 | 1.2039 | 1.1199 | 1.1548 | 0.8360 |
| 3-Sulfocatechol | 0.5086 | 1.4904 | 2.4648 | 1.4079 | 0.6805 | 1.2325 | 0.1847 | 0.9860 | 0.7232 | 0.4008 | 0.9214 |
| 4-Pyridoxate | 0.7720 | 1.5873 | 0.9380 | 0.8985 | 0.9612 | 1.6279 | 0.7515 | 0.8679 | 1.2226 | 0.7609 | 0.6173 |
| 5-Phospho-alpha-D-ribose 1-diphosphate | 1.3846 | 0.9995 | 0.7823 | 1.1058 | 1.2106 | 0.8604 | 0.9965 | 0.7914 | 0.8152 | 0.9114 | 1.1080 |
| 6-Phospho-D-gluconate | 0.8221 | 0.9939 | 1.3518 | 0.9936 | 0.9309 | 1.2104 | 0.7396 | 1.0180 | 1.1588 | 0.8574 | 0.9966 |
| Acetoacetate | 1.0945 | 0.9029 | 0.9584 | 0.9143 | 1.0139 | 0.9948 | 1.0221 | 1.0579 | 0.9043 | 1.0039 | 1.1392 |
| ADP | 0.9950 | 0.9847 | 1.1516 | 1.2697 | 1.0468 | 1.0076 | 0.5706 | 1.1555 | 1.0658 | 0.9390 | 0.9478 |
| alpha-D-Ribose 1-phosphate | 1.2369 | 0.7911 | 0.6323 | 1.1122 | 1.1030 | 0.8925 | 0.7689 | 0.9717 | 0.9371 | 0.9190 | 1.5347 |
| alpha-N-Peptidyl-L-glutamine | 1.2911 | 0.6168 | 0.3326 | 1.0823 | 1.0076 | 1.1196 | 0.9717 | 1.3068 | 0.9665 | 1.2627 | 1.0326 |
| Ascorbate | 0.9354 | 1.0182 | 0.9159 | 0.7309 | 0.6756 | 0.9758 | 1.0819 | 0.8419 | 1.7380 | 1.4650 | 0.5508 |
| Butanoic acid | 0.9940 | 0.8979 | 1.0284 | 0.9466 | 1.0853 | 0.9900 | 0.9662 | 1.0456 | 0.9018 | 0.9318 | 1.1960 |
| Catechin | 0.6273 | 0.9813 | 0.6423 | 0.6989 | 0.8658 | 1.3122 | 0.9832 | 1.1902 | 1.4000 | 0.8946 | 1.2054 |
| D-Alanyl-alanyl-poly(glycerolphosphate) | 1.2978 | 0.2801 | 0.6351 | 0.5659 | 0.9635 | 0.2252 | 0.6918 | 1.0719 | 3.2000 | 0.5491 | 1.1246 |
| Dehydroascorbate | 1.0639 | 1.0465 | 0.8370 | 0.8852 | 0.8836 | 0.9623 | 1.0788 | 0.9004 | 1.1610 | 1.1490 | 0.9733 |
| D-Erythrose 4-phosphate | 0.6281 | 1.0500 | 1.3504 | 0.9329 | 0.7417 | 1.2626 | 0.7423 | 1.2123 | 1.4108 | 0.8333 | 0.9123 |
| D-Fructose 1-6-bisphosphate | 1.1194 | 1.0399 | 1.0350 | 1.1121 | 0.9810 | 1.0137 | 0.5878 | 1.0475 | 1.1104 | 0.8346 | 1.1860 |
| D-Glucono-1-5-lactone 6-phosphate | 0.6424 | 1.0920 | 1.4116 | 0.9646 | 0.7677 | 1.3158 | 0.6528 | 1.1306 | 1.4099 | 0.7362 | 0.9560 |
| D-Glucose | 1.0668 | 0.9085 | 0.9469 | 0.9260 | 1.0287 | 0.9917 | 1.0575 | 1.0690 | 0.8853 | 0.9990 | 1.1189 |
| D-Glucose 6-phosphate | 0.5980 | 1.0731 | 1.3839 | 0.8816 | 0.7109 | 1.3174 | 0.7272 | 1.2267 | 1.4643 | 0.8607 | 0.8479 |
| D-Glyceraldehyde 3-phosphate/Glycerone phosphate | 0.9995 | 1.0739 | 0.9838 | 1.0275 | 1.0165 | 1.2186 | 1.0106 | 0.8745 | 0.8890 | 0.8995 | 0.9957 |
| Diphosphate | 1.3800 | 1.1746 | 0.8370 | 1.0798 | 1.1523 | 1.0359 | 0.7090 | 0.8002 | 0.9781 | 0.8201 | 1.0572 |
| Ethanolamine phosphate | 1.3327 | 0.8657 | 1.2515 | 0.9923 | 1.2174 | 0.5709 | 0.8682 | 1.1569 | 1.0387 | 1.0096 | 0.8494 |
| Fumarate | 1.1735 | 0.7317 | 0.6727 | 0.8908 | 0.8600 | 1.0593 | 0.8415 | 1.2877 | 1.0790 | 1.0876 | 1.3224 |
| Lactate | 0.8789 | 1.0359 | 0.9995 | 1.0054 | 0.9211 | 1.0612 | 1.0264 | 1.0142 | 1.0749 | 1.0636 | 0.9108 |
| Malate | 1.1290 | 0.7399 | 0.6770 | 0.9227 | 0.9079 | 1.0789 | 0.7941 | 1.2705 | 1.1043 | 1.0891 | 1.2839 |
| Muramic acid | 0.9337 | 0.9088 | 0.9816 | 0.9537 | 0.9332 | 0.7023 | 1.1511 | 0.8421 | 1.2367 | 1.0893 | 1.1290 |
| N-Amidino-L-aspartate | 0.7375 | 0.4129 | 0.3471 | 0.4914 | 0.4978 | 1.9483 | 1.2696 | 1.2780 | 1.7318 | 1.1032 | 0.9624 |
| N-Methylethanolamine phosphate | 1.1918 | 0.9966 | 1.1422 | 0.9814 | 1.0875 | 0.9224 | 0.6550 | 1.1832 | 0.8659 | 0.7739 | 1.3183 |
| Orthophosphate | 1.1922 | 1.1542 | 0.9417 | 0.9882 | 1.0718 | 1.0457 | 0.7553 | 0.9302 | 1.0621 | 0.8843 | 1.0078 |
| Oxaloacetate | 1.1252 | 0.9746 | 0.9935 | 1.0588 | 1.1114 | 1.0096 | 0.8747 | 0.9427 | 0.9544 | 0.9059 | 1.0611 |
| Oxalosuccinate | 1.6699 | 1.2615 | 0.6950 | 0.6659 | 1.0155 | 0.4747 | 1.5433 | 0.7342 | 1.0232 | 1.1713 | 0.7074 |
| Peptide tryptophan | 0.8673 | 0.4463 | 0.6012 | 0.4497 | 0.8368 | 0.5959 | 1.9561 | 1.2062 | 1.2646 | 1.6730 | 0.8553 |
| Pyruvate | 0.9301 | 1.0069 | 1.0307 | 1.0255 | 0.9654 | 1.0572 | 0.9860 | 0.9547 | 1.0330 | 0.9746 | 1.0184 |
| S-Acylglutathione | 0.9441 | 0.8324 | 1.5431 | 0.9426 | 0.9225 | 0.6227 | 0.9703 | 1.1456 | 0.9358 | 1.5972 | 0.7537 |
| Sedoheptulose 7-phosphate | 0.7175 | 1.0063 | 1.0717 | 0.9306 | 0.7939 | 1.2128 | 0.7635 | 1.2233 | 1.2480 | 1.0003 | 1.0613 |
| sn-glycero-3-Phosphoethanolamine | 0.9960 | 0.9785 | 1.3837 | 0.9995 | 1.4042 | 0.9938 | 1.0406 | 1.0726 | 0.3542 | 0.8368 | 1.0591 |
| sn-Glycerol 3-phosphate | 1.1521 | 0.9487 | 1.1724 | 1.1271 | 1.0857 | 0.8447 | 0.8818 | 1.0508 | 0.9460 | 0.8500 | 1.0274 |
| Succinate | 0.8831 | 1.0552 | 1.0392 | 0.7583 | 0.8032 | 1.2988 | 1.1147 | 1.0611 | 1.3177 | 0.8709 | 0.7896 |
| threo-3-Hydroxy-L-aspartate | 1.0996 | 1.5357 | 1.0631 | 0.8096 | 1.0190 | 0.8982 | 0.8613 | 1.0925 | 0.9454 | 0.9440 | 0.8479 |
Factors:
| F1 | time_point:I10 |
| F2 | time_point:I2 |
| F3 | time_point:I4 |
| F4 | time_point:I6 |
| F5 | time_point:I8 |
| F6 | time_point:LD10 |
| F7 | time_point:NP |
| F8 | time_point:P11-13 |
| F9 | time_point:P18-20 |
| F10 | time_point:P2-4 |
| F11 | time_point:R4 |
