Data for Assessing metabolic changes to maternal rat liver tissue during and post-pregnancy (part II) (Study ST000510)

(Analysis AN000783)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2F3F4F5F6F7
11(R)-HPETE/Leukotriene B4 (isobars) 1.0900 1.1434 0.8031 0.9545 1.0327 0.9725 0.9865
13(S)-HODE 1.0029 1.5394 0.8918 0.7786 0.9235 0.6178 1.2066
1-4-beta-D-Xylan 0.9051 1.1072 1.0527 1.0724 1.1428 0.7930 0.9412
2/3-Phospho-D-glycerate 0.5769 0.8951 0.9763 1.1556 1.3965 0.6188 1.5193
2-Oxoglutarate 1.0885 1.1933 0.8256 0.9717 1.2292 0.7779 0.8853
3alpha-7alpha-12alpha-Trihydroxy-5beta-cholanate 1.7395 1.3344 1.7665 0.2125 0.8289 0.4546 0.1502
4-Pyridoxate 0.6713 0.7928 0.6955 0.9921 2.1752 0.8560 0.7773
6-Phospho-D-gluconate 0.8037 0.9526 0.9176 1.9704 1.1541 0.3902 1.1617
9(S)-HODE 0.5116 1.1058 1.1712 1.3813 0.8574 0.4386 1.6031
Acetoacetate 0.8758 1.0959 1.0755 1.0668 1.1346 0.8402 0.9201
alhpa-tocopheronolactone 1.1367 0.8424 1.1142 1.0781 0.9374 0.7443 1.2075
AMP 0.8921 1.0312 0.8738 1.2627 1.0934 0.7996 1.1617
Catechin 1.0913 1.1778 0.8883 1.0446 1.2403 0.7463 0.7915
Citrate 1.0322 1.0137 1.0060 1.0197 1.2958 0.7950 0.8130
Cortisol 0.8620 0.7924 0.9171 2.0020 1.5716 0.3223 0.5191
Dehydroascorbate 1.0108 1.2312 0.8087 1.1184 1.2291 0.7312 0.8922
D-Erythrose 4-phosphate 1.0041 1.0673 0.9635 1.4905 1.0451 0.5549 1.0458
D-Glucono-1-5-lactone 6-phosphate 0.9714 1.1632 0.9357 1.4365 1.1291 0.4740 1.0427
D-Glucose 0.8775 1.1096 1.0464 1.0967 1.1606 0.8017 0.9277
D-Glucose 6-phosphate 1.0026 1.1759 0.9482 1.4151 1.0849 0.4848 1.0323
D-Glyceraldehyde 3-phosphate/Glycerone phosphate 0.9047 0.8366 0.9738 1.5823 0.9832 0.7440 1.2034
dihydroxy-hexadecanoic acid 0.6202 0.5547 0.7190 0.7326 2.2742 0.9086 1.1218
dihydroxy-octadecanoic acid 0.9683 1.0636 1.0488 0.7170 1.1069 0.9864 1.0176
Diphosphate 0.9914 1.0893 0.7218 1.4185 1.3743 0.5913 0.9436
Dodecanedioic acid 0.9864 1.0960 0.9936 0.9346 1.0472 0.9590 0.9536
D-O-Phosphoserine 0.8139 0.8275 1.1798 0.4517 0.7665 1.9437 0.8009
D-Rhamnose 0.4663 0.5710 0.7731 1.1297 1.9329 1.1445 1.0309
D-Ribose 0.8444 1.1326 1.0163 1.0954 1.2152 0.7744 0.9441
epoxy-octadecanoic acid 0.8055 0.5742 0.8732 1.1224 0.8754 0.6878 2.3228
Fumarate 0.8504 1.1768 0.8432 1.1884 1.3727 0.7110 0.9043
Glycocholate 1.5024 0.7357 0.8896 0.9904 1.8800 0.4816 0.1460
Heptanoic acid 1.0117 0.8597 0.9723 1.4370 0.9860 0.9336 0.9343
Hydroxyacetone phosphate 0.7428 1.1085 0.6879 1.4534 1.9942 0.4617 0.6433
hydroxy-dodecanedioic acid 1.0085 0.8905 0.9780 1.3603 0.9899 0.8080 1.1018
Icosatetraenoic acid 1.0156 1.4616 0.7206 1.1039 0.8140 0.8256 1.1694
Lactate 0.8899 0.9060 0.8879 1.1172 1.2843 0.8226 1.1574
Malate 0.5460 0.8566 1.0433 1.1465 1.5370 0.7846 1.1617
Maltose 0.7572 0.7525 1.1867 1.3520 1.4927 0.5670 1.0111
Maltotriose 0.6107 0.8469 1.2789 1.3575 1.3348 0.5423 1.1470
Mannitol 0.7333 1.1205 1.6107 0.9120 1.0070 0.7180 0.8431
Octanoic acid (caprylate) 1.0222 0.9476 1.0118 1.2454 0.9388 0.8050 1.1332
Oxaloacetate 0.9506 1.0273 0.9435 1.1905 1.1955 0.7837 0.9669
Pentose phosphates (isobars) 0.9876 1.1251 0.8194 1.2589 1.3090 0.6323 0.9448
Pyruvate 0.9245 1.0806 1.0322 0.9532 1.0950 0.9460 0.9435
Sedoheptulose 7-phosphate 1.0142 1.3668 0.8350 1.2962 1.1780 0.5185 0.8680
Succinate 0.5181 2.7005 0.8497 0.4993 0.8645 0.8170 0.5008
Sulfoglycolithocholate 1.0685 1.2212 1.0148 0.2000 1.0516 1.1909 0.6857
Taurochenodeoxycholate 0.9647 0.8414 0.9263 1.3375 1.0995 1.0783 0.8375
trihydroxy-octadecenoic acid 0.9376 1.0771 0.9613 1.0066 0.9591 1.0074 1.0636
Urate 0.5167 2.4588 1.1364 0.3826 0.2040 0.9542 1.1699
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Factors:

F1time_point:I2
F2time_point:I4
F3time_point:I6
F4time_point:I8
F5time_point:LD10
F6time_point:NP
F7time_point:R4
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