Data for Tubuloglomerular feedback and salt-sensitive hypertension (Study ST000757)
(Analysis AN001188)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 |
|---|---|---|---|---|---|---|
| 18:0 LYSO-PE (M-H)- | 1.7145 | 0.2628 | 1.5274 | 0.4493 | 0.6770 | NA |
| 2-HYDROXY-3-METHYLBUTYRIC ACID (M-H)- | 2.9910 | 0.2511 | 0.1401 | NA | 0.1879 | NA |
| 2-HYDROXY-4-(METHYLTHIO)BUTYRIC ACID (M-H)- | 1.0000 | NA | NA | NA | NA | NA |
| 2-HYDROXYBUTYRATE (M-H)- | 0.5824 | 1.0597 | NA | 2.1334 | NA | NA |
| 3-(4-HYDROXYPHENYL)LACTATE (M-H)- | 0.4762 | 1.2178 | 1.2316 | 1.3312 | 1.2865 | NA |
| 3-HYDROXY-3-METHYLGLUTARATE (M-H)- | 1.2215 | 0.8435 | 0.2844 | 2.7830 | 0.2906 | NA |
| 4-HYDROXY-2-QUINOLINECARBOXYLIC ACID-KRYNURENIC ACID (M-H)- | 0.8362 | 0.6396 | 1.4617 | NA | 1.1131 | NA |
| 4-HYDROXYBENZOATE (M-H)- | 1.3691 | NA | NA | NA | 0.2618 | NA |
| 5-VALEROLACTONE (M+HCOO)- | 1.0889 | 1.4784 | NA | NA | 0.2547 | NA |
| ADENOSINE 5^-MONOPHOSPHATE (M-H)- | 1.5663 | 1.3681 | 0.5999 | 0.7032 | 0.5980 | NA |
| ADIPIC ACID (M-H)- | 1.7875 | 0.2538 | 0.5326 | 1.5783 | 0.5302 | NA |
| BEHENIC ACID (M-H)- | 1.2731 | 0.8745 | 0.5357 | 1.9334 | 0.4813 | NA |
| BENZOATE (M-H)- | 0.8779 | 0.9874 | 1.0653 | 1.0499 | 1.1381 | NA |
| CHOLATE (M-H)- | 2.4451 | 0.5962 | 0.1250 | 0.0914 | 0.1280 | NA |
| CIS-11-EICOSENOIC ACID (M-H)- | 0.4912 | 1.6083 | 0.6784 | 2.9758 | 0.3278 | NA |
| CITRAMALATE (M-H)- | 1.9279 | 0.7777 | 0.6723 | 0.5650 | 0.6758 | NA |
| DEOXYADENOSINE (M+CL)- | 0.7230 | 0.9740 | 1.0108 | 2.1390 | 0.8665 | NA |
| DEOXYCHOLIC ACID (M+CL)- | 1.3794 | 0.7456 | 0.8259 | 0.7622 | 0.7826 | NA |
| DEOXYCHOLIC ACID (M-H)- | 0.8478 | 0.4824 | 1.9743 | NA | NA | NA |
| DEOXYURIDINE (M-H)- | 0.9282 | 1.2122 | 1.0970 | 1.2873 | 0.7034 | NA |
| ERUCIC ACID (M-H)- | 0.7249 | 1.4183 | 0.6907 | 2.5654 | 0.3663 | NA |
| GIBBERELLIC ACID [ISTD] (M-H)- | 0.8337 | 1.0832 | 1.0694 | 1.0963 | 1.0834 | NA |
| GLUCONIC ACID (M-H)- | 2.0387 | 0.3171 | 0.2540 | 0.7183 | 0.2773 | NA |
| GLYCOCHOLATE (M-H)- | 1.3237 | 1.9571 | NA | 0.0694 | 0.0226 | NA |
| HYODEOXYCHOLATE (M-H)- | 1.1443 | 1.1381 | 0.6712 | 0.2441 | 1.1879 | NA |
| ISOLEUCINE (M-H)- | 1.9559 | 0.7328 | 0.2380 | 0.5141 | 0.4574 | NA |
| LAURIC ACID (M-H)- | 0.4043 | 1.2562 | 0.6063 | 1.4770 | NA | NA |
| LITHOCHOLIC ACID (M+HCOO)- | 0.9818 | NA | 1.1935 | NA | 0.9306 | NA |
| MALATE (M-H)- | 1.0393 | 0.8944 | 1.1631 | 1.0031 | 0.9635 | NA |
| MEVALONIC ACID (M-H)- | 1.7907 | 0.6361 | 0.4653 | 1.2866 | 0.3019 | NA |
| OLEIC ACID (M-H)- | 0.5053 | 2.0790 | 0.5156 | 2.0965 | 0.3570 | NA |
| PANTOTHENATE (M+CL)- | 1.7468 | 0.6168 | NA | NA | 0.6363 | NA |
| PHENYLALANINE (M-H)- | 0.4991 | 1.2342 | 1.4831 | 0.9441 | 1.4207 | NA |
| RETINOATE (M-H)- | 1.7726 | 0.4561 | 0.7878 | 1.0779 | 0.8386 | NA |
| RIBOFLAVIN (M+CL)- | 1.0000 | NA | NA | NA | NA | NA |
| S-ADENOSYL-L-HOMOCYSTEINE (M-H)- | 1.2902 | 1.0973 | 0.7002 | 0.5416 | 0.8465 | NA |
| TRICOSANOIC ACID (M-H)- | 0.9207 | 1.2298 | 0.8448 | 1.2250 | 0.8543 | NA |
| TYROSINE (M-H)- | 0.3092 | 1.3594 | 0.6840 | 1.1200 | 1.0840 | NA |
| URATE (M-H)- | 0.7763 | 1.2215 | 1.2075 | 0.8444 | 1.0882 | NA |
| URIDINE (M-H)- | 0.9791 | 1.4732 | 0.9710 | 0.8606 | 0.6424 | NA |
| URSODIOL (M-H)- | 1.2006 | 0.4539 | 1.9431 | 0.5473 | NA | NA |
| URSODIOL (M+HCOO)- | 2.0325 | 0.8191 | 0.4320 | 0.1561 | 0.2477 | NA |
Factors:
| F1 | Days:30 days | Gene:non wild type | STZ injection:yes |
| F2 | Days:3 days | Gene:non wild type | STZ injection:yes |
| F3 | Days:3 days | Gene:wild type | STZ injection:no |
| F4 | Days:NA | Gene:non wild type | STZ injection:yes |
| F5 | Days:NA | Gene:wild type | STZ injection:no |
| F6 | Days:Pooled | Gene:Pooled plasma | STZ injection:Pooled plasma |
