Data for Targeting Myelin Sphingolipids of Kallikrein 6 Signals through PAR1 and PAR2 to Enchance Recovery of Function after SCI (Study ST000851)
(Analysis AN001375)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 | F5 | F6 | F7 | F8 | F9 | F10 |
|---|---|---|---|---|---|---|---|---|---|---|
| C14-cer | 1.0000 | 1.0000 | 1.0000 | 1.0000 | 1.0000 | NA | NA | NA | NA | NA |
| C16-cer | 1.2500 | 1.2500 | 1.2500 | 1.2500 | 1.2500 | 0.6250 | 1.2500 | 0.6250 | 0.6250 | 0.6250 |
| C16-dh cer | 1.1111 | 0.8333 | NA | 0.8333 | NA | NA | NA | NA | NA | NA |
| C18:1-cer | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| C18:1-dh cer | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| C18-cer | 1.3316 | 1.3378 | 1.1083 | 1.2309 | 1.1508 | 0.8348 | 1.1681 | 0.8411 | 0.5502 | 0.4465 |
| C18-dh cer | 2.2557 | 1.7672 | 1.3506 | 1.3649 | 1.3937 | 0.6034 | 0.4310 | 0.4023 | 0.2155 | 0.2155 |
| C20-cer | 1.5784 | 1.3824 | 1.0392 | 1.1961 | 1.2647 | 0.8873 | 0.9363 | 0.7304 | 0.5049 | 0.4804 |
| C22-cer | 1.3208 | 1.2383 | 1.0640 | 1.2476 | 1.2671 | 0.8898 | 1.1743 | 0.9176 | 0.4681 | 0.4124 |
| C24:1-cer | 1.1551 | 1.0594 | 0.9703 | 1.0503 | 1.0751 | 1.0611 | 1.1477 | 1.1518 | 0.6741 | 0.6551 |
| C24-cer | 1.4524 | 1.3092 | 1.0842 | 1.4354 | 1.5752 | 0.7262 | 0.9376 | 0.7740 | 0.3648 | 0.3409 |
| C8-cer | NA | NA | NA | NA | NA | NA | NA | NA | NA | NA |
| S1P | 1.1111 | 0.6349 | 0.9524 | 0.9524 | 1.2698 | 1.2698 | 1.2698 | 0.9524 | 0.9524 | 0.6349 |
| SPA | 1.5200 | 1.4400 | 1.2800 | 1.1200 | 1.5200 | 0.7200 | 0.6400 | 0.5600 | 0.7200 | 0.4800 |
| Sph | 0.9831 | 1.0508 | 0.8814 | 0.9153 | 1.1525 | 0.9831 | 1.0847 | 1.0169 | 1.1525 | 0.7797 |
Factors:
| F1 | time pt:P21d | grouping:CTRL |
| F2 | time pt:P21d | grouping:K6-/- |
| F3 | time pt:P21d | grouping:K6+/+ |
| F4 | time pt:P21d | grouping:PAR1 |
| F5 | time pt:P21d | grouping:PAR2 |
| F6 | time pt:P60d | grouping:PAR1-/- |
| F7 | time pt:P60d | grouping:PAR2-/- |
| F8 | time pt:P60d | grouping:Wt |
| F9 | time pt:P90d | grouping:K6-/- |
| F10 | time pt:P90d | grouping:K6+/+ |
