Data for Fatty Acid Oxidation is Impaired in An Orthologous Mouse Model of Autosomal Dominant Polycystic Kidney Disease (Study ST000878)

(Analysis AN001428)

Values for each metabolite have been scaled by dividing by the mean across all factors

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MetaboliteF1F2
1,2-cyclohexanedione 0.7455 1.1909
1,5-anhydroglucitol 0.8643 1.1018
1-kestose 0.2523 1.5608
1-methyladenosine 0.0979 1.6766
1-methylgalactose NIST 0.3214 1.5089
1-methylinosine NIST 1.5094 0.6180
1-monoolein 0.8500 1.1125
1-monostearin 0.8082 1.1438
2,5-dihydroxypyrazine NIST 0.6078 1.2941
2-deoxytetronic acid NIST 0.9923 1.0058
2-hydroxyglutaric acid 0.8113 1.1415
2-ketobutyric acid 1.1518 0.8861
2-monoolein 1.0071 0.9947
3-(3-hydroxyphenyl)propionic acid 0.3068 1.5199
3,6-anhydro-D-galactose 1.0507 0.9620
3-aminoisobutyric acid 1.0412 0.9691
3-hydroxybutyric acid 0.6484 1.2637
3-phosphoglycerate 0.4146 1.4391
4-hydroxyhippuric acid NIST 0.1301 1.6524
4-hydroxyphenylacetic acid 0.2374 1.5719
5^-deoxy-5^-methylthioadenosine 0.9946 1.0040
5-methoxytryptamine 1.0657 0.9507
aconitic acid 1.1689 0.8734
adenosine 0.9318 1.0512
adenosine-5-monophosphate 1.1763 0.8678
alanine 1.1167 0.9124
alanine-alanine 0.9839 1.0120
allantoic acid 0.1346 1.6491
alpha-aminoadipic acid 0.7365 1.1976
aminomalonate 1.2307 0.8270
arachidic acid 0.9149 1.0638
arachidonic acid 0.9736 1.0198
asparagine 1.3325 0.7506
aspartic acid 1.2617 0.8037
azelaic acid 0.6068 1.2949
beta-alanine 1.2193 0.8355
beta-gentiobiose 0.2990 1.5257
beta-glycerolphosphate 1.1452 0.8911
beta-sitosterol 1.1514 0.8865
bisphosphoglycerol NIST 0.8883 1.0838
butyrolactam NIST 0.4409 1.4193
capric acid 0.7271 1.2047
cholestan-3-ol 1.2943 0.7793
cholesterol 1.1084 0.9187
citric acid 0.8187 1.1360
citrulline 0.8228 1.1329
conduritol-beta-epoxide 0.4312 1.4266
creatinine 0.9082 1.0689
cysteine 1.2364 0.8227
cystine 1.0716 0.9463
cytidine-5-monophosphate NIST 1.2312 0.8266
dehydroascorbic acid 0.7769 1.1673
diacetone alcohol NIST 0.7388 1.1959
doconexent NIST 1.1642 0.8768
dodecanoic acid, isopropanol ester NIST 0.8424 1.1182
enolpyruvate NIST 1.0712 0.9466
erythritol 0.2975 1.5269
ethanolamine 1.1311 0.9017
fructose 1.5672 0.5746
fructose-1-phosphate 1.4909 0.6318
fructose-6-phosphate 0.7445 1.1916
fucose 0.1893 1.6081
fumaric acid 0.6220 1.2835
furoylglycine NIST 0.1452 1.6411
galactinol 0.8237 1.1323
galactonic acid 0.2389 1.5709
glucose 1.0214 0.9840
glucose-6-phosphate 0.5697 1.3228
glutamic acid 1.0229 0.9829
glutamine 0.6662 1.2504
glutaric acid 0.6332 1.2751
glyceric acid 0.7397 1.1952
glycerol 1.1859 0.8606
glycerol-3-galactoside 0.8184 1.1362
glycerol-alpha-phosphate 0.9398 1.0452
glycine 1.2240 0.8320
glycolic acid 0.7933 1.1550
guanosine 1.0001 0.9999
heptadecanoic acid 0.9376 1.0468
hexitol 0.9047 1.0714
hexonic acid 0.1979 1.6016
hexuronic acid 0.6448 1.2664
hippuric acid 0.0173 1.7371
histidine 0.4837 1.3873
homoserine 1.0486 0.9636
hydroxycarbamate NIST 0.8073 1.1445
hydroxylamine 0.6626 1.2530
hypoxanthine 1.1944 0.8542
indoxyl sulfate 0.3398 1.4952
inosine 1.1514 0.8864
inosine 5^-monophosphate 0.9395 1.0453
inositol-4-monophosphate 1.1740 0.8695
isoleucine 0.9734 1.0199
isothreonic acid 0.5666 1.3251
lactamide 1.1313 0.9015
lactic acid 1.2053 0.8461
lauric acid 0.7398 1.1952
leucine 1.0200 0.9850
linoleic acid 1.1647 0.8765
lysine 0.4443 1.4168
lyxitol 0.2341 1.5744
malic acid 0.3517 1.4862
maltose 0.3263 1.5052
mannose 1.0575 0.9569
methanolphosphate 0.8411 1.1191
methionine 1.2040 0.8470
mucic acid 0.2242 1.5819
myo-inositol 0.9401 1.0449
myristic acid 0.8863 1.0853
N-acetyl-D-galactosamine 0.5113 1.3665
N-acetyl-D-hexosamine 1.1087 0.9185
N-acetylglutamate 0.9956 1.0033
N-acetylglycine NIST 1.2256 0.8308
N-acetylputrescine 0.9313 1.0515
nicotinamide 1.3017 0.7737
N-methylalanine 0.9651 1.0262
octadecanol 0.8413 1.1190
octanol NIST 0.7927 1.1555
oleic acid 1.0111 0.9917
ornithine 0.8051 1.1462
orotic acid 0.3073 1.5195
oxalic acid 0.9873 1.0095
oxoproline 1.0371 0.9722
palmitic acid 0.8647 1.1015
palmitoleic acid 0.8210 1.1343
pantothenic acid 0.4781 1.3914
parabanic acid NIST 0.6043 1.2968
pelargonic acid 0.7938 1.1547
pentadecanoic acid 0.8973 1.0771
phenaceturic acid 0.2208 1.5844
phenol 1.0250 0.9813
phenylalanine 0.9246 1.0566
phenylethylamine 0.8896 1.0828
phosphate 1.0065 0.9951
phosphoenolpyruvate 0.6987 1.2260
phosphoethanolamine 0.8211 1.1342
phosphogluconic acid 1.2208 0.8344
pinitol 0.0449 1.7163
proline 1.1717 0.8712
propane-1,3-diol NIST 0.7805 1.1646
pseudo uridine 0.2935 1.5299
p-tolyl glucuronide 0.1598 1.6302
putrescine 0.9722 1.0208
pyrophosphate 1.0001 0.9999
pyruvic acid 1.0471 0.9647
raffinose 0.2289 1.5783
ribitol 1.5061 0.6205
ribonic acid 0.8341 1.1244
ribose 1.1414 0.8939
saccharic acid 0.1355 1.6484
serine 1.0556 0.9583
sorbitol 1.1687 0.8735
spermidine 1.0408 0.9694
stearic acid 0.8338 1.1246
succinic acid 1.1216 0.9088
sucrose 0.3086 1.5186
sulfuric acid 0.9354 1.0484
taurine 0.6617 1.2537
threitol 0.5125 1.3656
threonic acid 0.8188 1.1359
threonine 0.9421 1.0434
tocopherol alpha- 0.8471 1.1147
tryptophan 0.8318 1.1261
tyrosine 0.9360 1.0480
UDP-glucuronic acid 1.1465 0.8901
UDP-N-acetylglucosamine 0.9862 1.0103
uracil 1.0533 0.9600
urea 0.7020 1.2235
uric acid 0.6266 1.2801
uridine 0.9736 1.0198
uridine-5^-monophosphate 0.5723 1.3208
valine 0.9739 1.0196
xanthine 1.1678 0.8742
xanthurenic acid 0.2021 1.5984
xylitol 1.2111 0.8417
xylose 0.5958 1.3032
xylulose NIST 0.7281 1.2040
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Factors:

F1Treatment*:control
F2Treatment*:mutant
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