Data for Alterations in Lipid, Amino Acid, and Energy Metabolism Distinguish Crohn Disease from Ulcerative Colitis and Control Subjects by Serum Metabolomic Profiling (Study ST000899)
(Analysis AN001465)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 1-arachidonoyl-GPA (20:4) | 1.0384 | 1.0176 | 0.9419 |
| 1-palmitoyl-2-arachidonoyl-GPI (16:0/20:4) | 1.0344 | 1.0522 | 0.9134 |
| 1-palmitoyl-2-linoleoyl-GPI (16:0/18:2) | 1.0236 | 1.0865 | 0.8900 |
| 1-palmitoyl-2-oleoyl-GPI (16:0/18:1)* | 0.9738 | 1.2118 | 0.8131 |
| 1-stearoyl-2-arachidonoyl-GPI (18:0/20:4) | 1.1990 | 0.8629 | 0.9381 |
| 1-stearoyl-2-linoleoyl-GPI (18:0/18:2) | 1.0818 | 1.0038 | 0.9143 |
| 2,3-dihydroxyisovalerate | 0.4685 | 1.2281 | 1.1297 |
| 2-hydroxybutyrate/2-hydroxyisobutyrate | 1.3946 | 0.5534 | 1.0520 |
| 2-hydroxyglutarate | 1.1320 | 0.8784 | 0.9897 |
| 2-isopropylmalate | 1.2518 | 0.7677 | 1.0214 |
| 3-hydroxy-2-ethylpropionate | 1.1811 | 0.7755 | 1.0434 |
| 3-hydroxy-3-methylglutarate | 1.2256 | 0.7834 | 0.9910 |
| 3-hydroxybutyrate (BHBA) | 1.2024 | 0.1093 | 1.6882 |
| 3-hydroxyisobutyrate | 1.5632 | 0.6036 | 1.2674 |
| 3-methylglutaconate | 1.3525 | 0.7077 | 0.9398 |
| 5-acetylamino-6-amino-3-methyluracil | 1.2125 | 0.9163 | 0.8368 |
| 5-acetylamino-6-formylamino-3-methyluracil | 1.1243 | 0.8996 | 0.9187 |
| alanine | 1.0711 | 1.0329 | 0.8961 |
| allantoin | 1.0712 | 0.9021 | 1.0266 |
| alpha-ketoglutarate | 1.2112 | 0.7295 | 1.0593 |
| arabitol/xylitol | 1.1129 | 0.8533 | 1.0338 |
| arabonate/xylonate | 1.0861 | 0.8352 | 1.0787 |
| asparagine | 1.0949 | 0.9542 | 0.9509 |
| citrulline | 1.0359 | 0.9776 | 0.9864 |
| creatine | 1.3366 | 0.8103 | 0.8531 |
| dihydroorotate | 1.1035 | 0.8828 | 1.0145 |
| erythritol | 2.5242 | 0.2224 | 0.2535 |
| erythronate* | 1.1157 | 0.9033 | 0.9810 |
| ethylmalonate | 1.1915 | 0.7574 | 1.0511 |
| fructose | 0.8109 | 1.1660 | 1.0231 |
| fumarate | 1.1379 | 0.8264 | 1.0357 |
| galactonate | 0.6783 | 1.5971 | 0.5696 |
| gluconate | 1.1045 | 0.8317 | 1.0638 |
| glucose | 1.0474 | 0.9491 | 1.0035 |
| glucuronate | 1.0356 | 0.9009 | 1.0636 |
| glutarate (pentanedioate) | 0.8414 | 1.4187 | 0.7399 |
| glycerate | 1.1042 | 0.8247 | 1.0710 |
| glycerophosphoethanolamine | 0.9281 | 0.9276 | 1.1443 |
| glycerophosphorylcholine (GPC) | 0.9321 | 0.9192 | 1.1487 |
| guanidinoacetate | 1.0464 | 0.9390 | 1.0146 |
| gulonic acid* | 1.0202 | 0.8687 | 1.1287 |
| hydantoin-5-propionic acid | 1.0785 | 0.6392 | 1.2352 |
| imidazole lactate | 1.2391 | 0.8752 | 0.8857 |
| maleate | 0.9288 | 1.0967 | 0.9745 |
| malonate | 1.2097 | 0.8278 | 0.9626 |
| maltose | 0.8055 | 1.0982 | 1.0801 |
| mannitol/sorbitol | 1.0376 | 1.6017 | 0.3607 |
| mannose | 1.0716 | 0.7370 | 1.1915 |
| methylmalonate (MMA) | 1.1450 | 1.0081 | 0.8469 |
| methylsuccinate | 1.1183 | 0.8433 | 1.0383 |
| myo-inositol | 1.3549 | 0.7451 | 0.9000 |
| N-acetylalanine | 1.1450 | 0.8294 | 1.0256 |
| N-acetylaspartate (NAA) | 1.1945 | 0.7340 | 1.0716 |
| N-acetylglutamate | 1.1715 | 0.8799 | 0.9426 |
| N-acetylserine | 1.1718 | 0.7398 | 1.0884 |
| N-acetylthreonine | 1.1492 | 0.7583 | 1.0925 |
| N-delta-acetylornithine | 1.2108 | 0.9038 | 0.8853 |
| orotate | 1.0422 | 0.7609 | 1.1969 |
| orotidine | 1.0919 | 0.7514 | 1.1566 |
| phenylpyruvate | 1.0255 | 0.9956 | 0.9787 |
| pyruvate | 1.1983 | 0.8186 | 0.9831 |
| quinate | 0.9405 | 1.2787 | 0.6381 |
| ribitol | 1.0371 | 0.9172 | 1.0463 |
| ribonate | 1.0380 | 0.8312 | 1.1308 |
| salicylate | 0.1733 | 0.0899 | 2.7368 |
| serine | 1.1350 | 0.8369 | 1.0281 |
| succinate | 1.0946 | 0.8599 | 1.0456 |
| threonate | 1.0911 | 0.9243 | 0.9846 |
| trans-4-hydroxyproline | 1.2597 | 0.8811 | 0.8592 |
Factors:
| F1 | Type:Control |
| F2 | Type:Crohn disease |
| F3 | Type:Ulcerative Colitis |
