Data for Evidence that the metabolite repair enzyme NAD(P)HX epimerase has a moonlighting function (Study ST000900)
(Analysis AN001466)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 |
|---|---|---|---|
| 2,5-dihydroxypyrazine NIST | 1.0881 | 1.0222 | 0.8897 |
| 2,6-diaminopimelic acid | 1.2133 | 0.6351 | 1.1516 |
| 2-hydroxybutanoic acid | 1.4743 | 0.8330 | 0.6926 |
| 2-hydroxyglutaric acid | 1.1395 | 0.7186 | 1.1419 |
| 2-isopropylmalic acid | 1.2669 | 0.8820 | 0.8512 |
| 3-hydroxypalmitic acid | 1.5088 | 0.8013 | 0.6899 |
| 3-phosphoglycerate | 0.9908 | 1.0219 | 0.9873 |
| 4-hydroxybenzoate | 1.0594 | 0.9282 | 1.0124 |
| 5^-deoxy-5^-methylthioadenosine | 0.8901 | 0.9955 | 1.1145 |
| adenine | 0.8349 | 1.0803 | 1.0849 |
| adenosine-5-monophosphate | 1.0057 | 0.9827 | 1.0116 |
| alanine | 0.9631 | 1.0468 | 0.9901 |
| alpha-ketoglutarate | 1.3080 | 0.8240 | 0.8680 |
| arachidic acid | 0.7704 | 1.0741 | 1.1555 |
| asparagine | 0.7242 | 1.2842 | 0.9916 |
| aspartic acid | 0.6765 | 1.1819 | 1.1416 |
| benzoic acid | 0.9897 | 0.9960 | 1.0142 |
| beta-hydroxymyristic acid | 1.1378 | 1.0030 | 0.8592 |
| bisphosphoglycerol NIST | 0.9908 | 0.7725 | 1.2367 |
| capric acid | 0.8327 | 1.1278 | 1.0395 |
| citric acid | 0.9116 | 1.0149 | 1.0735 |
| cysteine-glycine | 1.1085 | 1.0404 | 0.8511 |
| dodecanoic acid, isopropanol ester NIST | 0.9823 | 1.1131 | 0.9046 |
| fructose | 0.9320 | 0.9666 | 1.1014 |
| fructose-1,6-bisphosphate | 0.8278 | 0.9467 | 1.2255 |
| fructose-6-phosphate | 0.8577 | 1.0259 | 1.1164 |
| fumaric acid | 0.7495 | 1.1959 | 1.0546 |
| galactose | 0.9382 | 0.8441 | 1.2176 |
| glucose | 0.8951 | 0.8316 | 1.2733 |
| glucose-1-phosphate | 0.9310 | 1.1148 | 0.9542 |
| glucose-6-phosphate | 0.8607 | 0.9520 | 1.1873 |
| glutamate | 1.0989 | 0.9086 | 0.9925 |
| glutamic acid | 0.9654 | 1.0155 | 1.0190 |
| glutamine | 0.8844 | 1.3273 | 0.7882 |
| glyceric acid | 0.9595 | 0.7984 | 1.2421 |
| glycerol-alpha-phosphate | 0.9417 | 0.9867 | 1.0715 |
| glycine | 0.9683 | 0.9926 | 1.0391 |
| glycolic acid | 0.9801 | 0.9348 | 1.0851 |
| guanine | 0.7333 | 0.9224 | 1.3443 |
| heptadecanoic acid | 0.8823 | 1.0718 | 1.0459 |
| hexadecane | 0.9713 | 1.0641 | 0.9646 |
| hexose-6-phosphate | 1.0490 | 0.9855 | 0.9656 |
| hydroxycarbamate NIST | 1.0242 | 0.8403 | 1.1355 |
| hydroxylamine | 1.0116 | 0.9721 | 1.0163 |
| hypoxanthine | 0.9502 | 1.0376 | 1.0122 |
| inosine-5^-monophosphate | 0.6984 | 1.0377 | 1.2639 |
| isoleucine | 0.7103 | 0.6889 | 1.6008 |
| isomaltose | 1.1302 | 1.0849 | 0.7849 |
| lactic acid | 1.3385 | 0.7823 | 0.8792 |
| lauric acid | 0.8869 | 0.7477 | 1.3653 |
| leucine | 0.7826 | 1.0915 | 1.1259 |
| levoglucosan | 0.9814 | 1.0195 | 0.9991 |
| lysine | 1.1337 | 0.6792 | 1.1870 |
| malic acid | 0.9493 | 0.9551 | 1.0955 |
| maltose | 2.4489 | 0.2654 | 0.2857 |
| mannitol | 1.0427 | 1.0471 | 0.9103 |
| mannose | 1.0517 | 0.8601 | 1.0882 |
| mannose-6-phosphate NIST | 0.7012 | 1.0901 | 1.2086 |
| methionine | 0.4695 | 1.2861 | 1.2444 |
| methyltetrahydrophenanthrenone3 NIST | 0.8422 | 1.1278 | 1.0300 |
| myristic acid | 0.8057 | 1.1193 | 1.0750 |
| N-acetylaspartic acid | 0.9898 | 0.6822 | 1.3279 |
| N-acetylglutamate | 0.6891 | 0.9019 | 1.4090 |
| N-carbamoylaspartate | 0.6163 | 1.5646 | 0.8191 |
| nicotinamide | 0.9201 | 1.0550 | 1.0249 |
| N-methylalanine | 0.9974 | 1.1777 | 0.8249 |
| norleucine | 1.4237 | 0.8481 | 0.7282 |
| norvaline | 1.9575 | 0.6345 | 0.4080 |
| octadecanol | 0.7736 | 1.3082 | 0.9182 |
| octanol NIST | 0.9942 | 0.9543 | 1.0515 |
| oleic acid | 0.9014 | 0.9269 | 1.1717 |
| O-phosphoserine | 0.4724 | 1.4267 | 1.1008 |
| orotic acid | 0.8611 | 1.1103 | 1.0285 |
| O-succinylhomoserine | 0.5492 | 1.1969 | 1.2540 |
| oxalic acid | 1.2530 | 0.7405 | 1.0065 |
| oxoproline | 1.0534 | 1.0414 | 0.9052 |
| palmitic acid | 0.8790 | 1.0540 | 1.0669 |
| palmitoleic acid | 0.8358 | 0.8596 | 1.3046 |
| pantothenic acid | 0.8665 | 1.2352 | 0.8983 |
| pelargonic acid | 0.9914 | 1.0778 | 0.9308 |
| phenylalanine | 0.7865 | 0.7526 | 1.4609 |
| phosphate | 1.0692 | 0.9218 | 1.0090 |
| phosphoenolpyruvate | 0.9576 | 1.0363 | 1.0061 |
| phosphoethanolamine | 0.9307 | 0.8949 | 1.1744 |
| proline | 1.0090 | 1.0639 | 0.9271 |
| propane-1,3-diol NIST | 0.9626 | 0.9458 | 1.0916 |
| putrescine | 0.9890 | 0.8186 | 1.1924 |
| pyrophosphate | 0.9938 | 0.9782 | 1.0280 |
| pyruvic acid | 0.9663 | 1.0646 | 0.9691 |
| ribose | 0.7758 | 1.1359 | 1.0883 |
| ribose-5-phosphate | 1.0059 | 1.0346 | 0.9594 |
| sarcosine | 0.9963 | 0.9884 | 1.0153 |
| serine | 0.5226 | 1.1864 | 1.2910 |
| spermidine | 0.5996 | 0.9700 | 1.4304 |
| stearic acid | 0.8285 | 1.1133 | 1.0582 |
| succinic acid | 1.0160 | 1.0734 | 0.9106 |
| sucrose | 0.7880 | 1.6135 | 0.5985 |
| sulfuric acid | 1.2555 | 0.6955 | 1.0490 |
| threonine | 0.9730 | 0.9131 | 1.1139 |
| thymidine-5-phosphate | 1.2069 | 1.0729 | 0.7202 |
| thymine | 1.0905 | 1.1261 | 0.7835 |
| trehalose | 2.9552 | 0.0238 | 0.0210 |
| tryptophan | 0.9805 | 0.8584 | 1.1611 |
| tyrosine | 0.8118 | 0.9415 | 1.2467 |
| UDP-N-acetylglucosamine | 0.7792 | 1.0374 | 1.1834 |
| uracil | 0.7814 | 1.5106 | 0.7080 |
| uridine-5-monophosphate | 0.9542 | 1.0371 | 1.0087 |
| valine | 0.8260 | 0.9642 | 1.2097 |
| xanthine | 0.7822 | 1.1581 | 1.0598 |
Factors:
| F1 | Treatment*:KA pt mut |
| F2 | Treatment*:wild type |
| F3 | Treatment*:yjeF KO |
