Data for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Plasma (Study ST000916)
(Analysis AN001492)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| 14-demethyl-14-dehydrolanosterol | 0.2193 | 1.5082 | 0.9493 | 1.4130 |
| 14-Demethyllanosterol | 1.4121 | 0.7801 | 0.9172 | 0.9247 |
| 19-hydroxycholesterol | NA | NA | NA | NA |
| 20-hydroxycholesterol | NA | NA | NA | NA |
| 22R-hydroxy-cholesterol | 0.8216 | 1.3594 | 0.9619 | 0.8461 |
| 24,25-epoxy-cholesterol | 0.6518 | 1.4706 | 0.8989 | 1.0199 |
| 24-dihydro Lanosterol | 1.0807 | 1.0343 | 0.8957 | 1.0599 |
| 24-oxocholesterol | 1.1000 | 1.0733 | 0.8082 | 1.1458 |
| 24S-hydroxy-cholesterol | 1.1786 | 1.0573 | 0.8744 | 0.9515 |
| 25-hydroxy-cholesterol | 0.8707 | 1.1282 | 1.0744 | 0.8656 |
| 25-hydroxy Vitamin D2 | 0.2186 | 0.9746 | 1.0529 | 1.6535 |
| 25-hydroxy Vitamin D3 | 0.6013 | 0.9015 | 1.3168 | 1.0073 |
| 27-hydroxy-cholesterol | 0.7616 | 1.2343 | 0.9841 | 1.0338 |
| 3beta,5alpha,6beta-trihydroxycholestanol | NA | NA | NA | NA |
| 3-oxo,7alpha-hydroxycholesterol | 0.2716 | 1.2558 | 0.9355 | 1.6737 |
| 4beta-hydroxy-cholesterol | 0.9700 | 0.8244 | 1.2441 | 0.7969 |
| 5,6alpha-epoxy-cholesterol | 0.7039 | 0.9966 | 1.0676 | 1.2292 |
| 5,6beta-epoxy-cholesterol | 0.6591 | 1.2392 | 1.0079 | 1.1053 |
| 5alpha,6alpha-24S,25-diepoxy-cholesterol | 1.0717 | 0.8315 | 0.5851 | 2.4022 |
| 5alpha-hydroxycholesterol | 0.6186 | 1.0601 | 1.0701 | 1.2501 |
| 6alpha-hydroxy-cholestanol | 1.6457 | 0.8847 | 0.8851 | 0.7255 |
| 7alpha,24S-dihydroxycholesterol | NA | NA | NA | NA |
| 7alpha,25-dihydroxycholesterol | 1.1075 | 0.9101 | 0.5707 | 1.7827 |
| 7alpha,27-dihydroxy cholesterol | 0.6093 | 1.2837 | 1.0533 | 1.0287 |
| 7alpha-hydroxy-cholesterol | 0.3529 | 1.5293 | 0.9373 | 1.2529 |
| 7-Dehydrochol | 0.4224 | 1.3718 | 0.8444 | 1.5259 |
| 7-oxo-cholesterol | 0.5766 | 1.9140 | 0.7995 | 0.7885 |
| 8-Dehydrochol | 0.4345 | 1.6886 | 0.7946 | 1.2297 |
| Campesterol | 1.2946 | 0.9398 | 0.8968 | 0.9124 |
| Cholestanol | 1.2424 | 0.8612 | 0.9608 | 0.9496 |
| Cholestenone | 0.5341 | 1.2462 | 1.1017 | 1.0731 |
| Cholesterol-total | 0.6456 | 1.1791 | 1.0494 | 1.1161 |
| Desmosterol | 0.8354 | 1.1909 | 0.8616 | 1.2215 |
| Lanosterol | 0.5162 | 1.3339 | 0.9766 | 1.1996 |
| Sitosterol | 1.6133 | 0.7717 | 0.8228 | 0.8701 |
| Stigmastanol | 1.4271 | 1.0223 | 0.7742 | 0.8831 |
| Stigmasterol | 1.4621 | 0.8550 | 0.9114 | 0.8815 |
| Zymosterol | 0.8187 | 0.9439 | 0.7569 | 1.6667 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
