Data for Biomarkers of NAFLD progression: a lipidomics approach to an epidemic. Part 2:Plasma (Study ST000916)
(Analysis AN001495)Values for each metabolite have been scaled by dividing by the mean across all factors Run Hierarchial cluster analysis on this study | Run Heatmap cluster analysis on this study| Metabolite | F1 | F2 | F3 | F4 |
|---|---|---|---|---|
| C14 Cer | 0.9316 | 1.0018 | 1.0442 | 0.9978 |
| C14DH Cer | 1.0852 | 0.8182 | 1.0270 | 1.0645 |
| C14DH HexCer | 1.2090 | 0.8607 | 0.9922 | 0.9322 |
| C14DH Sphingomyelin | 0.8781 | 1.0893 | 0.9758 | 1.0825 |
| C14 GalCer | 0.8184 | 1.0892 | 1.1813 | 0.7888 |
| C14 GlcCer | 1.0086 | 1.0180 | 1.0242 | 0.9245 |
| C14 HexCer | 0.9905 | 1.0265 | 1.0374 | 0.9118 |
| C14 Sphingomyelin | 0.8887 | 1.0649 | 0.9905 | 1.0719 |
| C16 1-deoxyCer | 1.4447 | 0.9393 | 0.8523 | 0.8176 |
| C16 Cer | 1.0002 | 1.1350 | 0.9424 | 0.9461 |
| C16DH 1-deoxyCer | 0.6146 | 1.2920 | 1.1589 | 0.8201 |
| C16DH Cer | 1.0121 | 1.1370 | 0.9112 | 0.9865 |
| C16DH HexCer | 1.1701 | 0.9033 | 1.0139 | 0.8883 |
| C16DH Sphingomyelin | 1.0038 | 1.0848 | 0.9358 | 1.0129 |
| C16 GalCer | 0.8590 | 1.3394 | 0.8724 | 0.9994 |
| C16 GlcCer | 1.1075 | 1.0761 | 0.9439 | 0.8862 |
| C16 HexCer | 1.1032 | 1.0807 | 0.9427 | 0.8881 |
| C16 Sphingomyelin | 1.0477 | 1.0806 | 0.9597 | 0.9225 |
| C18:1 Cer | 0.8108 | 1.0826 | 1.0142 | 1.0995 |
| C18 1-deoxyCer | 0.5632 | 1.1077 | 1.1011 | 1.2029 |
| C18:1DH Cer | 0.8422 | 1.0685 | 0.9947 | 1.1148 |
| C18:1DH HexCer | 1.0676 | 0.8646 | 1.0525 | 0.9840 |
| C18:1 GalCer | 0.7804 | 1.2099 | 0.9745 | 1.0579 |
| C18:1 GlcCer | 0.9270 | 1.0604 | 0.9881 | 1.0364 |
| C18:1 HexCer | 0.9157 | 1.0719 | 0.9871 | 1.0381 |
| C18:1 Sphingomyelin | 0.5101 | 1.1669 | 1.1245 | 1.1530 |
| C18 Cer | 0.4534 | 1.3928 | 1.0546 | 1.0812 |
| C18DH 1-deoxyCer | 0.3179 | 1.3408 | 1.1594 | 1.1109 |
| C18DH Cer | 0.6636 | 1.3758 | 0.9466 | 1.0510 |
| C18DH HexCer | 1.1661 | 1.0445 | 1.0135 | 0.7277 |
| C18DH Sphingomyelin | 0.5631 | 1.3627 | 0.9622 | 1.1562 |
| C18 GalCer | 0.9125 | 1.2658 | 1.0049 | 0.7817 |
| C18 GlcCer | 0.9460 | 1.1715 | 0.9857 | 0.8879 |
| C18 HexCer | 0.9451 | 1.1756 | 0.9856 | 0.8843 |
| C18 Sphingomyelin | 0.5345 | 1.2737 | 1.0926 | 1.0567 |
| C20 1-deoxyCer | 0.7714 | 1.0953 | 1.0191 | 1.1220 |
| C20 Cer | 0.5915 | 1.2791 | 1.0669 | 1.0302 |
| C20DH 1-deoxyCer | 0.3878 | 1.3506 | 1.1323 | 1.0665 |
| C20DH Cer | 0.9107 | 1.1628 | 0.9739 | 0.9612 |
| C20DH HexCer | 1.4277 | 0.9491 | 0.9515 | 0.6333 |
| C20DH Sphingomyelin | 0.7852 | 1.1635 | 1.0018 | 1.0570 |
| C20 GalCer | 1.0584 | 1.1085 | 0.8804 | 1.0216 |
| C20 GlcCer | 1.2784 | 1.0621 | 0.8729 | 0.8313 |
| C20 HexCer | 1.2711 | 1.0637 | 0.8731 | 0.8376 |
| C20 Sphingomyelin | 0.4966 | 1.2248 | 1.0974 | 1.1502 |
| C22 1-deoxyCer | 0.6798 | 1.1444 | 1.0122 | 1.1846 |
| C22 Cer | 0.4861 | 1.3330 | 1.0726 | 1.0805 |
| C22DH 1-deoxyCer | 0.3552 | 1.4284 | 1.1116 | 1.0509 |
| C22DH Cer | 0.8529 | 1.2551 | 0.9043 | 1.0474 |
| C22DH HexCer | 1.0645 | 1.1387 | 0.9214 | 0.9039 |
| C22DH Sphingomyelin | 0.4865 | 1.2513 | 1.0667 | 1.1868 |
| C22 GalCer | 1.1130 | 1.0763 | 0.8227 | 1.1188 |
| C22 GlcCer | 1.3447 | 1.0190 | 0.8336 | 0.8688 |
| C22 HexCer | 1.3406 | 1.0201 | 0.8336 | 0.8728 |
| C22 Sphingomyelin | 0.5124 | 1.3130 | 1.0819 | 1.0561 |
| C24:1 1-deoxyCer | 0.9447 | 1.1278 | 0.9494 | 1.0070 |
| C24:1 Cer | 0.6717 | 1.2506 | 0.9985 | 1.0943 |
| C24 1-deoxyCer | 0.6278 | 1.1488 | 1.0246 | 1.2180 |
| C24:1DH 1-deoxyCer | 0.6618 | 1.3983 | 1.0319 | 0.8713 |
| C24:1DH Cer | 0.7310 | 1.2813 | 0.9097 | 1.1503 |
| C24:1DH HexCer | 1.6453 | 0.7279 | 0.8345 | 0.8628 |
| C24:1 GalCer | 0.3141 | 1.5203 | 1.1527 | 0.9164 |
| C24:1 GlcCer | 1.7390 | 0.8542 | 0.7419 | 0.7727 |
| C24:1 HexCer | 1.6729 | 0.8851 | 0.7610 | 0.7794 |
| C24:1 Sphingomyelin | 0.8790 | 1.0723 | 1.0295 | 1.0034 |
| C24 Cer | 0.4634 | 1.2399 | 1.0977 | 1.1709 |
| C24DH 1-deoxyCer | 0.4490 | 1.4126 | 1.0905 | 0.9977 |
| C24DH Cer | 0.9125 | 1.1553 | 0.8742 | 1.1497 |
| C24DH HexCer | 1.5047 | 0.8811 | 0.7860 | 0.8981 |
| C24DH Sphingomyelin | 0.5321 | 1.2243 | 1.0592 | 1.1786 |
| C24 GalCer | 1.2140 | 1.1830 | 0.7281 | 1.0288 |
| C24 GlcCer | 1.6410 | 0.8687 | 0.7797 | 0.8021 |
| C24 HexCer | 1.6338 | 0.8739 | 0.7788 | 0.8059 |
| C24 Sphingomyelin | 0.6638 | 1.2774 | 1.0242 | 1.0250 |
| C26:1 1-deoxyCer | 1.8558 | 0.8045 | 0.7665 | 0.6489 |
| C26:1 Cer | 0.8700 | 1.0328 | 1.0161 | 1.0851 |
| C26 1-deoxyCer | 1.2617 | 1.1218 | 0.7339 | 1.0341 |
| C26:1DH 1-deoxyCer | 0.7316 | 1.4836 | 1.0347 | 0.6834 |
| C26:1DH Cer | 0.9857 | 0.9656 | 0.9812 | 1.0916 |
| C26:1DH HexCer | 1.2593 | 0.6326 | 0.9480 | 1.2373 |
| C26:1 GalCer | 0.8476 | 0.8954 | 0.9663 | 1.3865 |
| C26:1 GlcCer | 1.8258 | 0.7580 | 0.7535 | 0.7627 |
| C26:1 HexCer | 1.7046 | 0.7767 | 0.7815 | 0.8321 |
| C26:1 Sphingomyelin | 1.0231 | 1.0139 | 0.9740 | 1.0038 |
| C26 Cer | 0.7368 | 1.0259 | 1.0690 | 1.1534 |
| C26DH 1-deoxyCer | 0.6209 | 1.4582 | 1.0676 | 0.7614 |
| C26DH Cer | 1.1539 | 0.8083 | 0.9538 | 1.1287 |
| C26DH HexCer | 1.1731 | 0.6980 | 1.0970 | 0.9570 |
| C26DH Sphingomyelin | 0.5354 | 1.2678 | 1.0756 | 1.0936 |
| C26 GalCer | 0.9484 | 1.2795 | 0.7863 | 1.1216 |
| C26 GlcCer | 1.5412 | 0.9018 | 0.8197 | 0.8076 |
| C26 HexCer | 1.4351 | 0.9695 | 0.8137 | 0.8638 |
| C26 Sphingomyelin | 0.6677 | 1.2673 | 1.0328 | 1.0166 |
| Sphinganine | 0.9327 | 1.0978 | 0.9421 | 1.0698 |
| Sphinganine-P | 0.6074 | 1.1238 | 1.0742 | 1.1810 |
| Sphingosine | 0.6426 | 0.8710 | 1.0895 | 1.4090 |
| Sphingosine-P | 0.6108 | 0.9970 | 1.0808 | 1.3141 |
Factors:
| F1 | Diagnosis:Cirrhosis |
| F2 | Diagnosis:NASH |
| F3 | Diagnosis:Normal |
| F4 | Diagnosis:Steatosis |
